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NO934852D0 - Hexahydronafthalenesterderivater, deres fremstilling og terapeutiske anvendelse - Google Patents

Hexahydronafthalenesterderivater, deres fremstilling og terapeutiske anvendelse

Info

Publication number
NO934852D0
NO934852D0 NO934852A NO934852A NO934852D0 NO 934852 D0 NO934852 D0 NO 934852D0 NO 934852 A NO934852 A NO 934852A NO 934852 A NO934852 A NO 934852A NO 934852 D0 NO934852 D0 NO 934852D0
Authority
NO
Norway
Prior art keywords
hydrogen
preparation
therapeutic use
ester derivatives
alkyl
Prior art date
Application number
NO934852A
Other languages
English (en)
Other versions
NO300730B1 (no
NO934852L (no
Inventor
Hiroshi Kogen
Sadao Ishihara
Teiichiro Koga
Eiichi Kitazawa
Nobufusa Serizawa
Kiyoshi Hamano
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO934852D0 publication Critical patent/NO934852D0/no
Publication of NO934852L publication Critical patent/NO934852L/no
Publication of NO300730B1 publication Critical patent/NO300730B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/33Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with hydroxy compounds having more than three hydroxy groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0093Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Indole Compounds (AREA)
NO934852A 1992-12-28 1993-12-27 Heksahydronaftalenesterderivater og farmasöytiske preparater inneholdende disse NO300730B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34903492 1992-12-28

Publications (3)

Publication Number Publication Date
NO934852D0 true NO934852D0 (no) 1993-12-27
NO934852L NO934852L (no) 1994-06-29
NO300730B1 NO300730B1 (no) 1997-07-14

Family

ID=18401049

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934852A NO300730B1 (no) 1992-12-28 1993-12-27 Heksahydronaftalenesterderivater og farmasöytiske preparater inneholdende disse

Country Status (23)

Country Link
US (2) US5451688A (no)
EP (1) EP0605230B1 (no)
JP (1) JPH06247894A (no)
KR (1) KR100286596B1 (no)
CN (1) CN1039642C (no)
AT (1) ATE157346T1 (no)
AU (1) AU670468B2 (no)
CA (1) CA2112442A1 (no)
CZ (1) CZ280492B6 (no)
DE (1) DE69313427T2 (no)
DK (1) DK0605230T3 (no)
ES (1) ES2108238T3 (no)
FI (1) FI935895A7 (no)
GR (1) GR3025412T3 (no)
HK (1) HK1000937A1 (no)
HU (1) HU221845B1 (no)
IL (1) IL108194A (no)
MX (1) MX9400060A (no)
NO (1) NO300730B1 (no)
NZ (1) NZ250609A (no)
RU (1) RU2104997C1 (no)
TW (1) TW289753B (no)
ZA (1) ZA939741B (no)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114250254A (zh) * 2021-12-20 2022-03-29 宁夏清研高分子新材料有限公司 一种对羟基苯甲酸的微生物合成方法

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JPH0251582A (ja) * 1988-08-12 1990-02-21 Kyokado Eng Co Ltd 地盤注入用薬液
US5989877A (en) * 1995-08-03 1999-11-23 Gist-Brocades B.V. Selective process for the deacylation of acylated compounds
KR100186758B1 (ko) * 1996-08-09 1999-04-01 영진약품공업 주식회사 프라바스타틴(pravastatin)전구체의제조방법
CA2226996C (en) * 1997-01-24 2006-08-15 Kose Corporation Whitening cosmetic composition comprising polyhydric alcohol
EP1007033B1 (en) * 1997-08-28 2008-04-23 Novartis AG Lymphocyte function antigen-1 antagonists
DE19848597C2 (de) * 1998-04-16 2000-04-20 Georg Dietz Zubereitung aus Calciumhydroxid, einem zwei- oder mehrwertigen Alkohol und einem fetten Öl vegetarischen oder animalischen Ursprungs und seine Verwendung zur Kollagenneubildung
SI20305A (sl) * 1999-08-06 2001-02-28 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristali natrijeve soli pravastatina
US6682913B1 (en) 1999-02-03 2004-01-27 Institute For Drug Research Ltd. Microbial process for preparing pravastatin
CO5140104A1 (es) * 1999-02-16 2002-03-22 Novartis Ag Derivados de mevinolina y preparacion farmaceuticas que los contienen
AU751849B2 (en) * 1999-03-08 2002-08-29 Kitasato Institute, The Substances WK-5344A and WK-5344B and process for producing the same
HUP9902352A1 (hu) * 1999-07-12 2000-09-28 Gyógyszerkutató Intézet Kft. Eljárás pravasztatin mikrobiológiai előállítására
JP3881240B2 (ja) * 1999-11-30 2007-02-14 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ 醗酵ブロスからスタチン化合物を回収するための方法
IL150187A0 (en) 1999-12-14 2002-12-01 Biogal Pharmaceutical Co Ltd Novel forms of pravastatin sodium
IL155194A0 (en) * 2000-10-05 2003-11-23 Biogal Pharmaceutical Co Ltd Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
JP3236282B1 (ja) * 2000-10-16 2001-12-10 三共株式会社 プラバスタチンを精製する方法
JP2002121172A (ja) * 2000-10-16 2002-04-23 Sankyo Co Ltd プラバスタチン又はその薬理上許容される塩の精製方法
KR100458151B1 (ko) * 2001-05-14 2004-11-26 씨제이 주식회사 프락토실 트랜스퍼라제를 생산하는 신규 미생물 및 이를이용하여 프락토올리고당 및 네오프락토올리고당을생산하는 방법
RU2206330C1 (ru) * 2002-05-30 2003-06-20 Кулемин Леонид Михайлович Средство, обладающее иммуномодулирующей, энтеросорбционной, антитоксической и противовоспалительной активностью и способ его получения
US7071197B2 (en) 2002-06-14 2006-07-04 Recordati S.A. N,N-disubstituted diazocycloalkanes
ITMI20021327A1 (it) * 2002-06-14 2003-12-15 Recordati Chem Pharm Nuove ossialchilpiperazine
US7029178B2 (en) * 2002-10-04 2006-04-18 Ght Ventures, Llc Zip-lock closure
DE202004020671U1 (de) * 2003-11-24 2005-12-08 Teva Gyogyszergyar Reszvenytarsasag Pravastatin
US20070185193A1 (en) * 2003-12-01 2007-08-09 Huaibei Huike Pharmaceutical, Co. Ltd. Huvastatin and its preparation and formulation comprising the huvastatin
CN1277826C (zh) * 2003-12-01 2006-10-04 叶红平 辉伐他汀及其合成方法和以辉伐他汀为原料药的制剂
WO2005121062A2 (en) * 2004-06-09 2005-12-22 Ranbaxy Laboratories Limited Process for the preparation of pravastatin
RU2007115522A (ru) * 2004-10-12 2008-10-27 Декод Дженетикс Ехф (Is) Пери-замещенные бициклические карбоновые кислоты для лечения окклюзионного заболевания артерий
TWI307360B (en) 2004-12-03 2009-03-11 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Process for constructing strain having compactin hydroxylation ability
US20090068325A1 (en) * 2007-09-10 2009-03-12 Gil Depicciotto Method of treatment of fresh produce
EP2241561A1 (en) * 2009-04-16 2010-10-20 Neuron Biopharma, S.A. Neuroprotective, hypocholesterolemic and antiepileptic compound
ES2380473B1 (es) * 2010-10-13 2013-02-19 Neuron Biopharma, S.A. Compuesto neuroprotector, hipocolesterolémico, antiinflamatorio y antiepiléptico.
US9796752B2 (en) 2013-03-19 2017-10-24 Daiichi Sankyo Company, Limited Terpenoid derivatives
CN108546721B (zh) * 2018-04-20 2021-04-13 安徽大学 一种利用微生物合成对羟基苯甲酸的方法
US20240150279A1 (en) * 2021-02-01 2024-05-09 The University Of Toledo C prime agents for treating metabolic disorders

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114250254A (zh) * 2021-12-20 2022-03-29 宁夏清研高分子新材料有限公司 一种对羟基苯甲酸的微生物合成方法
CN114250254B (zh) * 2021-12-20 2024-01-05 宁夏清研高分子新材料有限公司 一种对羟基苯甲酸的微生物合成方法

Also Published As

Publication number Publication date
EP0605230B1 (en) 1997-08-27
FI935895A7 (fi) 1994-10-19
CN1039642C (zh) 1998-09-02
DK0605230T3 (da) 1998-04-20
KR940014294A (ko) 1994-07-18
TW289753B (no) 1996-11-01
HU9303762D0 (en) 1994-04-28
AU670468B2 (en) 1996-07-18
ZA939741B (en) 1994-08-15
RU2104997C1 (ru) 1998-02-20
CZ280492B6 (cs) 1996-01-17
US5827855A (en) 1998-10-27
DE69313427T2 (de) 1998-03-26
US5451688A (en) 1995-09-19
NZ250609A (en) 1995-07-26
CA2112442A1 (en) 1994-06-29
JPH06247894A (ja) 1994-09-06
IL108194A0 (en) 1994-04-12
IL108194A (en) 1998-02-22
CZ290093A3 (en) 1994-08-17
AU5269993A (en) 1994-07-07
NO300730B1 (no) 1997-07-14
ATE157346T1 (de) 1997-09-15
HK1000937A1 (en) 1998-05-08
HU221845B1 (hu) 2003-02-28
HUT65593A (en) 1994-07-28
ES2108238T3 (es) 1997-12-16
FI935895A0 (fi) 1993-12-28
MX9400060A (es) 1994-07-29
CN1094707A (zh) 1994-11-09
KR100286596B1 (ko) 2001-04-16
NO934852L (no) 1994-06-29
GR3025412T3 (en) 1998-02-27
DE69313427D1 (de) 1997-10-02
EP0605230A1 (en) 1994-07-06

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