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NO934320L - T celle reseptor peptider som terapeutiske midler for immum-relaterte sykdommer - Google Patents

T celle reseptor peptider som terapeutiske midler for immum-relaterte sykdommer

Info

Publication number
NO934320L
NO934320L NO934320A NO934320A NO934320L NO 934320 L NO934320 L NO 934320L NO 934320 A NO934320 A NO 934320A NO 934320 A NO934320 A NO 934320A NO 934320 L NO934320 L NO 934320L
Authority
NO
Norway
Prior art keywords
immune
cell receptor
therapeutic agents
related diseases
tcr
Prior art date
Application number
NO934320A
Other languages
English (en)
Other versions
NO934320D0 (no
Inventor
Arthur Allen Vandenbark
Original Assignee
Xoma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Corp filed Critical Xoma Corp
Publication of NO934320D0 publication Critical patent/NO934320D0/no
Publication of NO934320L publication Critical patent/NO934320L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Peptider og farmasøytiske sammensetninger omfattende immunogene peptider av en markør T celle reseptor (TCR) karakteristisk for en immun-relatert sykdom som kan forhindre, undertrykke eller behandle sykdommen, er beskrevet. I en foretrukket utførelsesform tilsvarer aminosyresekvensen til peptidet i det minste en del av en komplementårltetsbes-temmende region (CDR) eller en hypervariabel region til TCR. Antistoffer og/eller T celler som er immunologisk reaktive for TCR peptidet som kan forhindre, undertrykke eller behandle en immun- relatert sykdom ved passiv overføring er også beskrevet.
NO934320A 1991-05-31 1993-11-29 T celle reseptor peptider som terapeutiske midler for immum-relaterte sykdommer NO934320L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70802291A 1991-05-31 1991-05-31
US73561291A 1991-07-16 1991-07-16
PCT/US1992/004492 WO1992021367A1 (en) 1991-05-31 1992-06-01 T cell receptor peptides as therapeutics for immune-related disease

Publications (2)

Publication Number Publication Date
NO934320D0 NO934320D0 (no) 1993-11-29
NO934320L true NO934320L (no) 1994-01-27

Family

ID=27108005

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934320A NO934320L (no) 1991-05-31 1993-11-29 T celle reseptor peptider som terapeutiske midler for immum-relaterte sykdommer

Country Status (11)

Country Link
EP (1) EP0587735B1 (no)
JP (1) JPH07502977A (no)
AT (1) ATE189230T1 (no)
AU (1) AU674494B2 (no)
CA (1) CA2110055C (no)
DE (1) DE69230612T2 (no)
DK (1) DK0587735T3 (no)
ES (1) ES2144418T3 (no)
GR (1) GR3033318T3 (no)
NO (1) NO934320L (no)
WO (1) WO1992021367A1 (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5667967A (en) * 1990-05-01 1997-09-16 The Board Of Trustees Of The Leland Stanford Junior University T-cell receptor varible transcripts as disease related markers
US5776459A (en) * 1989-07-19 1998-07-07 Connetics Corporation TCR V beta 5 peptides
AU689091B2 (en) * 1992-12-18 1998-03-26 Cell Med, Inc. Assay and treatment for demyelinating diseases such as multiple sclerosis
GB9308581D0 (en) * 1993-04-26 1993-06-09 Univ Manitoba A method for induction of antigen-specific suppression of immune-response
EP0698087A1 (en) * 1993-05-14 1996-02-28 Dr. L. Willems Instituut Human t cell monoclone, process for its production and its use, diagnostic of infectious diseases, autoimmune diseases, t-cell mediated allergies and cancer
WO1995008572A1 (en) * 1993-09-22 1995-03-30 The Board Of Trustees For The Leland Stanford Junior University Interaction of t-cell receptors and antigen in autoimmune disease
US5552300A (en) * 1994-01-13 1996-09-03 T Cell Sciences, Inc. T cell antigen receptor V region proteins and methods of preparation thereof
US6329499B1 (en) * 1994-11-18 2001-12-11 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein
US6251396B1 (en) 1994-11-18 2001-06-26 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6379670B1 (en) 1994-11-18 2002-04-30 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
DE69525544T2 (de) * 1994-11-18 2002-08-22 Neurocrine Biosciences, Inc. Peptidanaloga des menschlichen myelinbasischen proteins mit substitution in position 91 zur behandlung von multipler sklerose
AU5360796A (en) * 1995-03-09 1996-10-02 Neurocrine Biosciences, Inc. Peptide analogues of human myelin basic protein useful in treating multiple sclerosis
IL113159A0 (en) * 1995-03-28 1995-06-29 Yeda Res & Dev Synthetic peptides and pharmaceutical compositions comprising them
AU2651997A (en) * 1996-05-10 1997-12-05 Kirin Beer Kabushiki Kaisha T-cell receptor alpha-chain constant-region peptides, processes for producing the peptides, and use thereof
WO1998042377A1 (fr) 1997-03-21 1998-10-01 Chugai Seiyaku Kabushiki Kaisha Substances servant a la prevention ou au traitement de maladies liees a la cellule-t sensibilisee contenant comme principe actif des antagonistes de l'il-6
EP2050814A1 (en) 2007-10-17 2009-04-22 Txcell Compositions for treating multiple sclerosis
WO2015145449A2 (en) * 2014-03-27 2015-10-01 Yeda Research And Development Co. Ltd. T-cell receptor cdr3 peptides and antibodies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886743A (en) * 1985-04-24 1989-12-12 California Institute Of Technology Diagnostic reagents based on unique sequences within the variable region of the T cell receptor and uses thereof
KR920700674A (ko) * 1989-03-21 1992-08-10 원본미기재 특정 t세포 집단에 의한 발명 반응으로부터 야기되는 질병에 대한 예방접종 및 방법
DE69031919T3 (de) * 1989-07-19 2005-01-27 Connetics Corp., Palo Alto T-zell-rezeptor-peptide als heilmittel für autoimmune und bösartige krankheiten
CA2101065A1 (en) * 1991-01-22 1992-07-23 Mark D. Howell Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations

Also Published As

Publication number Publication date
CA2110055C (en) 2002-08-20
EP0587735A1 (en) 1994-03-23
DK0587735T3 (da) 2000-09-11
JPH07502977A (ja) 1995-03-30
EP0587735B1 (en) 2000-01-26
EP0587735A4 (en) 1995-05-03
CA2110055A1 (en) 1992-12-10
GR3033318T3 (en) 2000-09-29
DE69230612T2 (de) 2000-06-21
AU2147292A (en) 1993-01-08
AU674494B2 (en) 1997-01-02
ES2144418T3 (es) 2000-06-16
NO934320D0 (no) 1993-11-29
ATE189230T1 (de) 2000-02-15
DE69230612D1 (de) 2000-03-02
WO1992021367A1 (en) 1992-12-10

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