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NO923271L - expression - Google Patents

expression

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Publication number
NO923271L
NO923271L NO92923271A NO923271A NO923271L NO 923271 L NO923271 L NO 923271L NO 92923271 A NO92923271 A NO 92923271A NO 923271 A NO923271 A NO 923271A NO 923271 L NO923271 L NO 923271L
Authority
NO
Norway
Prior art keywords
expression systems
desired polypeptide
cdna
vector
expression
Prior art date
Application number
NO92923271A
Other languages
Norwegian (no)
Other versions
NO923271D0 (en
Inventor
Melvyn Hollis
Maurice Ronald Charles Needham
Clare Gooding
Franklin Geradus Grosveld
Michael Antoniou
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909027917A external-priority patent/GB9027917D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of NO923271D0 publication Critical patent/NO923271D0/en
Publication of NO923271L publication Critical patent/NO923271L/en

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Abstract

Ekspresjonssystemer som omfatter en pattedyr-vert slik. som erytroide celler, transformert med en vektor som omfatter en promotor, en DNA-sekvens som koder for et ønsket polypeptid og et dominant kontrollområde. Vektorene og fremgangs-måtene for fremstilling av polypeptidene ved bruk av ekspresjonssystemene er også beskrevet. I en foretrukket utførelsesform inneholder vektoren cDNA for det ønskede poly-peptidet og en sekvens som er i stand til å stabilisere mRNA laget fra cDNA. Disse ekspresjonssystemene er spesielt effektive og i stand til å utskille det ønskede polypeptidet.Expression systems comprising such a mammalian host. as erythroid cells, transformed with a vector comprising a promoter, a DNA sequence encoding a desired polypeptide and a dominant control region. The vectors and methods of making the polypeptides using the expression systems are also described. In a preferred embodiment, the vector contains cDNA for the desired polypeptide and a sequence capable of stabilizing mRNA made from cDNA. These expression systems are particularly effective and capable of secreting the desired polypeptide.

NO92923271A 1990-12-21 1992-08-20 expression NO923271L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909027917A GB9027917D0 (en) 1990-12-21 1990-12-21 Expression systems
PCT/GB1991/002274 WO1992011380A1 (en) 1990-12-21 1991-12-19 Expression systems

Publications (2)

Publication Number Publication Date
NO923271D0 NO923271D0 (en) 1992-08-20
NO923271L true NO923271L (en) 1992-10-16

Family

ID=26298168

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92923271A NO923271L (en) 1990-12-21 1992-08-20 expression

Country Status (1)

Country Link
NO (1) NO923271L (en)

Also Published As

Publication number Publication date
NO923271D0 (en) 1992-08-20

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