[go: up one dir, main page]

NO922316L - Forbedret konjugert polysakkarid meningokokkvaksine - Google Patents

Forbedret konjugert polysakkarid meningokokkvaksine

Info

Publication number
NO922316L
NO922316L NO92922316A NO922316A NO922316L NO 922316 L NO922316 L NO 922316L NO 92922316 A NO92922316 A NO 92922316A NO 922316 A NO922316 A NO 922316A NO 922316 L NO922316 L NO 922316L
Authority
NO
Norway
Prior art keywords
meningocokkvaksine
polysaccharid
conjugated
improved
improved conjugated
Prior art date
Application number
NO92922316A
Other languages
English (en)
Other versions
NO305275B1 (no
NO922316D0 (no
Inventor
Harold J Jennings
Francis Michon
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Publication of NO922316D0 publication Critical patent/NO922316D0/no
Publication of NO922316L publication Critical patent/NO922316L/no
Publication of NO305275B1 publication Critical patent/NO305275B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
NO922316A 1989-12-14 1992-06-12 FremgangsmÕte ved fremstilling av modifisert gruppe B polysakkarid fra Neisseria meningitidis eller modifisert E.coli K1 kapsulµrt polysakkarid NO305275B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44819589A 1989-12-14 1989-12-14
PCT/CA1990/000437 WO1991008772A1 (en) 1989-12-14 1990-12-13 Improved meningococcal polysaccharide conjugate vaccine

Publications (3)

Publication Number Publication Date
NO922316D0 NO922316D0 (no) 1992-06-12
NO922316L true NO922316L (no) 1992-08-14
NO305275B1 NO305275B1 (no) 1999-05-03

Family

ID=23779371

Family Applications (2)

Application Number Title Priority Date Filing Date
NO922316A NO305275B1 (no) 1989-12-14 1992-06-12 FremgangsmÕte ved fremstilling av modifisert gruppe B polysakkarid fra Neisseria meningitidis eller modifisert E.coli K1 kapsulµrt polysakkarid
NO973311A NO307835B1 (no) 1989-12-14 1997-07-17 Ikke-farmasøytisk polysakkaridkonjugat

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO973311A NO307835B1 (no) 1989-12-14 1997-07-17 Ikke-farmasøytisk polysakkaridkonjugat

Country Status (30)

Country Link
US (3) US5576002A (no)
EP (1) EP0504202B1 (no)
JP (1) JP2637845B2 (no)
KR (1) KR0158436B1 (no)
CN (4) CN1049223C (no)
AR (1) AR243934A1 (no)
AT (1) ATE121947T1 (no)
AU (1) AU641715B2 (no)
BR (1) BR9007917A (no)
CA (1) CA2071811C (no)
CZ (1) CZ283530B6 (no)
DE (1) DE69019164T2 (no)
DK (1) DK0504202T3 (no)
ES (1) ES2071288T3 (no)
FI (2) FI104539B (no)
HR (1) HRP920872A2 (no)
HU (2) HU218146B (no)
IE (1) IE68414B1 (no)
IL (1) IL96676A (no)
IN (1) IN171747B (no)
NO (2) NO305275B1 (no)
NZ (1) NZ236471A (no)
PH (1) PH30305A (no)
PL (2) PL166659B1 (no)
RO (1) RO111416B1 (no)
RU (1) RU2105568C1 (no)
SI (1) SI20008B (no)
WO (1) WO1991008772A1 (no)
YU (1) YU24391A (no)
ZA (1) ZA9010065B (no)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648241A (en) * 1989-09-15 1997-07-15 The General Hospital Corporation Conjugate vaccine against group B streptococcus
WO1991008772A1 (en) * 1989-12-14 1991-06-27 National Research Council Of Canada Improved meningococcal polysaccharide conjugate vaccine
ATE203167T1 (de) * 1992-09-24 2001-08-15 Brigham & Womens Hospital Gruppe b streptococcus typ ii und typ v polysaccharid-protein konjugate als impfstoffe
US5439808A (en) * 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US6153406A (en) * 1993-07-23 2000-11-28 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane protein P2 from Haemophilus influenzae type B
US5679654A (en) * 1994-09-02 1997-10-21 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5700787A (en) * 1994-09-02 1997-12-23 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5747287A (en) * 1995-04-28 1998-05-05 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
ATE205724T1 (de) * 1995-06-07 2001-10-15 Smithkline Beecham Biolog Vakzine mit einem polysaccharide antigen- trägerprotein konjugat und freien trägerprotein
US6284884B1 (en) 1995-06-07 2001-09-04 North American Vaccine, Inc. Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2,5-anhydro-D-mannose terminal structure and conjugate vaccine thereof
US5811102A (en) 1995-06-07 1998-09-22 National Research Council Of Canada Modified meningococcal polysaccharide conjugate vaccines
ZA97248B (en) * 1996-01-18 1997-07-18 Rohm & Haas Method for identifying and quantifying polymers utilizing immunoassay techniques
DE69708318T3 (de) † 1996-08-27 2006-11-16 Novartis Vaccines and Diagnostics, Inc., Emeryville Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung
WO1998008874A1 (en) * 1996-08-27 1998-03-05 Chiron Corporation Monoclonal antibodies that define unique meningococcal b epitopes and their use in the preparation of vaccine compositions
US6426074B1 (en) 1997-03-19 2002-07-30 The Brigham And Women's Hospital Inc. Group B Streptococcus vaccine
JP2002506448A (ja) 1997-06-24 2002-02-26 カイロン コーポレイション 抗髄膜炎菌ワクチン組成物を使用して成体を免疫する方法
AU9120898A (en) * 1997-08-27 1999-03-16 Chiron Corporation Molecular mimetics of meningococcal b epitopes
EP1051506B2 (en) 1997-12-23 2019-08-21 Pfizer Ireland Pharmaceuticals Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugates vaccines
PL346645A1 (en) * 1998-08-19 2002-02-25 North American Vaccine IMMUNOGENIC β-PROPIONAMIDO-LINKED POLYSACCHARIDE PROTEIN CONJUGATE USEFUL AS A VACCINE PRODUCED USING AN N-ACRYLOYLATED POLYSACCHARIDE
WO2000010599A2 (en) * 1998-08-19 2000-03-02 North American Vaccine, Inc. IMMUNOGENIC β-PROPIONAMIDO-LINKED POLYSACCHARIDE PROTEIN CONJUGATE USEFUL AS A VACCINE PRODUCED USING AN N-ACRYLOYLATED POLYSACCHARIDE
US6436653B1 (en) 1998-12-15 2002-08-20 Exiqon A/S Method for introduction of reporter groups into bacterial lipopolysaccharide-derived carbohydrates and the subsequent coupling of such derivatives onto solid surfaces
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
US6518037B2 (en) * 1999-11-12 2003-02-11 University Of Iowa Research Foundation Two-component system that controls bacterial membrane synthesis
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
GB0011108D0 (en) * 2000-05-08 2000-06-28 Microscience Ltd Virulence gene and protein and their use
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
CN1306956C (zh) * 2001-04-17 2007-03-28 希龙公司 诱导功能活性抗体的脑膜炎球菌b抗原表位的分子模拟物
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
GB0121591D0 (en) * 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
NZ535968A (en) * 2002-03-26 2006-08-31 Chiron S Modified saccharides having improved stability in water
MXPA04011248A (es) * 2002-05-14 2005-02-17 Chiron Srl Vacunas mucosales en combinacion para la meningitis bacteriana.
RU2317106C2 (ru) * 2002-08-02 2008-02-20 ГлаксоСмитКлайн Байолоджикалз с.а. Нейссериальные вакцинные композиции, содержащие комбинацию антигенов
GB0227346D0 (en) * 2002-11-22 2002-12-31 Chiron Spa 741
AU2004227852B2 (en) * 2003-03-31 2010-01-14 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
WO2005016974A1 (en) * 2003-08-12 2005-02-24 Lipoxen Technologies Limited Sialic acid derivatives for protein derivatisation and conjugation
US8148335B2 (en) 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy
BRPI0512413A (pt) 2004-06-23 2008-03-04 Childrens Hosp & Res Ct Oak derivados de polissacarìdeo e usos na indução de uma resposta imune
GB0428394D0 (en) * 2004-12-24 2005-02-02 Chiron Srl Saccharide conjugate vaccines
UA95237C2 (uk) 2005-06-27 2011-07-25 Ґлаксосмітклайн Байолоджікалз С.А. Імуногенна композиція
US8206726B2 (en) 2006-02-06 2012-06-26 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
GB0611914D0 (en) 2006-06-15 2006-07-26 Teti Giuseppe Peptides that mimic non-human cross-reactive protective epitopes of the group Bmeningococcal capsulsar polysaccharide
EP1872791A1 (en) * 2006-06-30 2008-01-02 Institut Pasteur Use of bacterial polysaccharides for biofilm inhibition
CN101754773A (zh) * 2007-06-20 2010-06-23 巴克斯特国际有限公司 用于缀合疫苗的经过修饰的多糖
ES2664753T3 (es) 2007-12-07 2018-04-23 Glaxosmithkline Biologicals Sa Composiciones de inducción de respuestas inmunes
US9050283B2 (en) 2009-01-16 2015-06-09 University Of Maryland, Baltimore Broad spectrum vaccine against non-typhoidal Salmonella
EP2731617A4 (en) 2011-07-12 2015-07-01 Brigham & Womens Hospital LIPID-BASED PSA COMPOSITIONS, METHOD FOR THEIR INSULATION AND USE METHOD THEREFOR
EP2752403A1 (de) * 2013-01-08 2014-07-09 Sika Technology AG Amin für emissionsarme Epoxidharz-Produkte
CN108135167B (zh) 2015-08-19 2021-07-09 哈佛学院院长及董事 脂化psa组合物和方法
EP3484441A4 (en) 2016-07-15 2020-03-18 President and Fellows of Harvard College GLYCOLIPID COMPOSITIONS AND METHOD FOR USE
PE20191107A1 (es) * 2017-01-31 2019-08-26 Pfizer Composiciones de neisseria meningitidis y metodos respectivos

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4057685A (en) * 1972-02-02 1977-11-08 Abbott Laboratories Chemically modified endotoxin immunizing agent
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4673574A (en) * 1981-08-31 1987-06-16 Anderson Porter W Immunogenic conjugates
US4644059A (en) * 1982-07-06 1987-02-17 Connaught Laboratories, Inc. Haemophilus influenzae B polysaccharide-diptheria toxoid conjugate vaccine
US4496538A (en) * 1982-07-06 1985-01-29 Connaught Laboratories, Inc. Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine
US4619828A (en) * 1982-07-06 1986-10-28 Connaught Laboratories, Inc. Polysaccharide exotoxoid conjugate vaccines
US4695624A (en) * 1984-05-10 1987-09-22 Merck & Co., Inc. Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
US4727136A (en) * 1985-10-01 1988-02-23 Canadian Patents And Development Ltd. Modified meningococcal group B polysaccharide for conjugate vaccine
WO1991008772A1 (en) * 1989-12-14 1991-06-27 National Research Council Of Canada Improved meningococcal polysaccharide conjugate vaccine

Also Published As

Publication number Publication date
NO973311L (no) 1992-08-14
CN1072506C (zh) 2001-10-10
DE69019164D1 (de) 1995-06-08
CN1055541A (zh) 1991-10-23
FI19991917A7 (fi) 1999-09-09
CZ628490A3 (en) 1997-12-17
HRP920872A2 (en) 1997-06-30
IE904513A1 (en) 1991-06-19
CN1100428A (zh) 1995-03-22
IL96676A (en) 1996-09-12
NZ236471A (en) 1992-10-28
HU9201966D0 (en) 1992-10-28
RO111416B1 (ro) 1996-10-31
HU218146B (hu) 2000-06-28
PL166659B1 (pl) 1995-06-30
IE68414B1 (en) 1996-06-12
US5683699A (en) 1997-11-04
PH30305A (en) 1997-02-20
US5576002A (en) 1996-11-19
BR9007917A (pt) 1992-10-20
US5902586A (en) 1999-05-11
CN1036522C (zh) 1997-11-26
WO1991008772A1 (en) 1991-06-27
KR0158436B1 (ko) 1998-12-01
RU2105568C1 (ru) 1998-02-27
CA2071811A1 (en) 1991-06-15
EP0504202A1 (en) 1992-09-23
EP0504202B1 (en) 1995-05-03
CZ283530B6 (cs) 1998-04-15
CN1100656A (zh) 1995-03-29
FI104539B (fi) 2000-02-29
CN1049223C (zh) 2000-02-09
YU24391A (sh) 1995-12-04
ATE121947T1 (de) 1995-05-15
JPH05505392A (ja) 1993-08-12
ZA9010065B (en) 1992-02-26
AU641715B2 (en) 1993-09-30
NO973311D0 (no) 1997-07-17
SI20008B (en) 2001-02-28
AR243934A1 (es) 1993-09-30
FI19991917L (fi) 1999-09-09
DE69019164T2 (de) 1995-09-07
IN171747B (no) 1992-12-26
FI922737A0 (fi) 1992-06-12
NO307835B1 (no) 2000-06-05
AU6898791A (en) 1991-07-18
ES2071288T3 (es) 1995-06-16
DK0504202T3 (da) 1995-10-02
CA2071811C (en) 2003-11-04
SI20008A (sl) 2000-02-29
IL96676A0 (en) 1991-09-16
JP2637845B2 (ja) 1997-08-06
PL288271A1 (en) 1991-12-16
NO305275B1 (no) 1999-05-03
PL166035B1 (pl) 1995-03-31
CN1036504C (zh) 1997-11-26
HUT64480A (en) 1994-01-28
NO922316D0 (no) 1992-06-12
CN1096516A (zh) 1994-12-21

Similar Documents

Publication Publication Date Title
NO922316D0 (no) Forbedret konjugert polysakkarid meningokokkvaksine
BR8906392A (pt) Conexao
DE59000343D1 (de) Schaelmesser.
DE59007662D1 (de) Karde.
DK0385610T3 (da) Konjugater
DE69020982D1 (de) Vulkanisierungsform.
DK0382322T3 (da) Forbindelsesliste
DE69011307D1 (de) Modifizierter Asphalt.
FI915769A0 (fi) Permanent taetning foer paofyllningsbehaollare.
DE69014770D1 (de) Trennschalter.
DE59010722D1 (de) 2,4-Dimethyl-6-s-alkylphenole
IT9020625A0 (it) cuscinetto
DE59004522D1 (de) Mikrodosiergerät.
DE69020041D1 (de) Ladungsgekoppelte Vorrichtungen.
FI901177A7 (fi) Tiofeenejä
FI890299L (fi) Form.
FI906116A0 (fi) 17/21-alkylerade 19-norprogesteronderivat.
BR9000750A (pt) Conexao segmental
DE69008037D1 (de) Satteldecke.
FI903559A0 (fi) Faestanordning foer baerhandtag.
UA13213A1 (uk) Пересувhа виправочhо-підбивочhо-обробhа машиhа
FI890300L (fi) Form.
BR8905286A (pt) Maquina conjugada
FI904454A0 (fi) Insektresistent elkabel.
BR6602561U (pt) Copa-cozinha conjugada