[go: up one dir, main page]

NO922005L - Farmasoeytiske preparater - Google Patents

Farmasoeytiske preparater

Info

Publication number
NO922005L
NO922005L NO92922005A NO922005A NO922005L NO 922005 L NO922005 L NO 922005L NO 92922005 A NO92922005 A NO 92922005A NO 922005 A NO922005 A NO 922005A NO 922005 L NO922005 L NO 922005L
Authority
NO
Norway
Prior art keywords
polyethylene glycol
capsule
dissolved
filler
weight
Prior art date
Application number
NO92922005A
Other languages
English (en)
Other versions
NO922005D0 (no
Inventor
Alfred Paul Launchbury
Frank Samuel Short Morton
Dennis Rowe
Original Assignee
Erba Farmitalia
Scherer Ltd R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia, Scherer Ltd R P filed Critical Erba Farmitalia
Publication of NO922005D0 publication Critical patent/NO922005D0/no
Publication of NO922005L publication Critical patent/NO922005L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

En farmasøytisk enhetsdoseform omfattende et myk- gelatlnkapselskall eller en todelt hårdgelatlnkapsel og et fyllstoff omfattende et benzodiazepin, opplest eller suspendert i en gel, der gelen har et dryppepunkt (C) før innkapsling på minst 46 og består av minst 63 % polyetylenglykol 600, minst 4 vekt-* polyetylenglykol 4000 eller 6000 og minst 21 vekt-56 av en mellomliggende polyetylenglykol. Gel-fyllmaterlalet som benyttes ifølge oppfinnelsen kan ikke presses ut fra noen sprøyte ved omgivelsestempera- tur og fjerner derfor tilgjengeligheten for intravenøs- medikament-misbrukere av en kapsel inneholdende et medikament, oppløst eller dlspergert i et flytende fyllstoff. Kapselfyllet bibeholder god biotilgjengelig- het og farmakoklnetiske egenskaper.
NO92922005A 1989-11-24 1992-05-21 Farmasoeytiske preparater NO922005L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898926612A GB8926612D0 (en) 1989-11-24 1989-11-24 Pharmaceutical compositions
PCT/GB1990/001821 WO1991007950A1 (en) 1989-11-24 1990-11-23 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
NO922005D0 NO922005D0 (no) 1992-05-21
NO922005L true NO922005L (no) 1992-05-21

Family

ID=10666868

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92922005A NO922005L (no) 1989-11-24 1992-05-21 Farmasoeytiske preparater

Country Status (10)

Country Link
EP (1) EP0502042B1 (no)
AU (1) AU652924B2 (no)
DE (1) DE69018647T2 (no)
DK (1) DK0502042T3 (no)
FI (1) FI922364A0 (no)
GB (2) GB8926612D0 (no)
NO (1) NO922005L (no)
PT (1) PT95991B (no)
WO (1) WO1991007950A1 (no)
ZA (1) ZA909426B (no)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660859A (en) * 1994-12-29 1997-08-26 Mcneil-Ppc, Inc. Gelling agent for polyethylene glycol
NZ280610A (en) * 1994-12-29 1997-08-22 Mcneil Ppc Inc Soft gelatin-like pharmaceutical carrier: gelled polyethylene glycol and dispersed active agent
US5919481A (en) * 1996-06-28 1999-07-06 Ncneil-Ppc, Inc. Fill material for soft gelatin pharmaceutical dosage form
US6024980A (en) * 1996-06-28 2000-02-15 Mcneil-Ppc, Inc. Multiphase soft gelatin dosage form
US5908636A (en) * 1996-06-28 1999-06-01 Mcneil-Ppc, Inc. Fill material for soft gelatin pharmaceutical dosage form containing an antiflatulent
FR2787715B1 (fr) * 1998-12-23 2002-05-10 Synthelabo Composition pharmaceutique comprenant un compose hypnotique ou un de ses sels pharmaceutiquement acceptables
CA2452871C (en) 2001-07-06 2011-10-04 Endo Pharmaceuticals, Inc. Oxymorphone controlled release formulations
ATE376832T1 (de) 2001-07-06 2007-11-15 Penwest Pharmaceuticals Co Verzögert freisetzende formulierungen von oxymorphon
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
WO2003013481A1 (en) * 2001-08-03 2003-02-20 Bakulesh Mafatlal Khamar The process of manufacturing pharmaceutical composition with increased content of poorly soluble pharmaceutical ingredients
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US20030068276A1 (en) 2001-09-17 2003-04-10 Lyn Hughes Dosage forms
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
CA2507522C (en) 2002-12-13 2015-02-24 Durect Corporation Oral drug delivery system
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
EP3326617A1 (en) 2004-06-12 2018-05-30 Collegium Pharmaceutical, Inc. Abuse-deterrent drug formulations
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
PT1809329E (pt) 2004-09-17 2012-03-29 Durect Corp Composição anestésica local prolongada contendo aibs
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
CN104825397A (zh) 2006-04-03 2015-08-12 伊萨·奥迪迪 含有机溶胶涂层的受控释放递送物件
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
EP2484347A1 (en) 2006-11-03 2012-08-08 Durect Corporation Transdermal delivery systems comprising bupivacaine
EP2067471B1 (en) 2007-12-06 2018-02-14 Durect Corporation Oral pharmaceutical dosage forms
AU2009207796B2 (en) 2008-01-25 2014-03-27 Grunenthal Gmbh Pharmaceutical dosage form
AU2009243681B2 (en) 2008-05-09 2013-12-19 Grunenthal Gmbh Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
AR077420A1 (es) 2009-07-22 2011-08-24 Gruenenthal Gmbh Forma de dosificacion resistente a la manipulacion para opiaceos sensibles a la oxidacion
MX2012000317A (es) 2009-07-22 2012-02-08 Gruenenthal Gmbh Forma de dosificacion de liberacion controlada extruida por fusion en caliente.
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
NZ607392A (en) 2010-09-02 2015-03-27 Gruenenthal Chemie Tamper resistant dosage form comprising inorganic salt
JP5933553B2 (ja) 2010-09-02 2016-06-15 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング アニオン性ポリマーを含む不正使用抵抗性剤形
PE20181177A1 (es) 2010-12-22 2018-07-20 Purdue Pharma Lp Formas de dosis de liberacion controlada encerradas resistentes a manipulaciones indebidas
PH12013501345A1 (en) 2010-12-23 2022-10-24 Purdue Pharma Lp Tamper resistant solid oral dosage forms
SI2736495T1 (sl) 2011-07-29 2017-12-29 Gruenenthal Gmbh Tableta, odporna proti zlorabi, ki zagotavlja takojšnje sproščanje zdravila
AR087359A1 (es) 2011-07-29 2014-03-19 Gruenenthal Gmbh Tableta a prueba de alteracion que proporciona liberacion inmediata del farmaco
EP2819656A1 (en) 2012-02-28 2015-01-07 Grünenthal GmbH Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
TR201815502T4 (tr) 2012-04-18 2018-11-21 Gruenenthal Gmbh Kurcalama veya dirençli ve doz boşalımına dirençli farmasötik dozaj formu.
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
WO2014123899A1 (en) 2013-02-05 2014-08-14 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
AU2014233453A1 (en) 2013-03-15 2015-10-01 Durect Corporation Compositions with a rheological modifier to reduce dissolution variability
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
US10420729B2 (en) 2013-03-15 2019-09-24 R.P. Scherer Technologies, Llc Abuse resistant capsule
US10154966B2 (en) 2013-05-29 2018-12-18 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
CA2913209A1 (en) 2013-05-29 2014-12-04 Grunenthal Gmbh Tamper resistant dosage form with bimodal release profile
CN105682643B (zh) 2013-07-12 2019-12-13 格吕伦塔尔有限公司 含有乙烯-醋酸乙烯酯聚合物的防篡改剂型
AU2014306759B2 (en) 2013-08-12 2018-04-26 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
CN105934241B (zh) 2013-11-26 2020-06-05 格吕伦塔尔有限公司 通过低温研磨制备粉末状药物组合物
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
AU2015261060A1 (en) 2014-05-12 2016-11-03 Grunenthal Gmbh Tamper resistant immediate release capsule formulation comprising Tapentadol
CN106456550A (zh) 2014-05-26 2017-02-22 格吕伦塔尔有限公司 避免乙醇剂量倾泻的多颗粒
GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
DK3169315T3 (da) * 2014-07-17 2020-08-10 Pharmaceutical Manufacturing Res Services In Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse
WO2016064873A1 (en) 2014-10-20 2016-04-28 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
US9908976B2 (en) * 2015-03-18 2018-03-06 Psmg, Llc Stable polyethylene glycol particle dispersions and methods for forming the stable dispersions
HK1246173A1 (zh) 2015-04-24 2018-09-07 Grünenthal GmbH 具有立即释放和对溶剂萃取的抗性的抗篡改剂型
EP3346991A1 (en) 2015-09-10 2018-07-18 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
WO2017205939A1 (en) * 2016-06-03 2017-12-07 Indigo Ridge Pty Ltd Vitamin d formulations and therapeutic uses thereof
WO2017222575A1 (en) 2016-06-23 2017-12-28 Collegium Pharmaceutical, Inc. Process of making more stable abuse-deterrent oral formulations
CA3028450A1 (en) 2016-07-06 2018-01-11 Durect Corporation Oral dosage form with drug composition, barrier layer and drug layer
US11266631B2 (en) 2016-10-11 2022-03-08 Purdue Pharmaceutical Products L.P. Hodgkin lymphoma therapy
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
CA3124005A1 (en) 2018-12-18 2020-06-25 Mundipharma International Corporation Limited Compounds for treating multiple myeloma
CN115666621A (zh) 2020-01-13 2023-01-31 度勒科特公司 具有减少的杂质的持续释放药物递送系统及相关方法
CA3203561A1 (en) 2021-01-12 2022-07-21 Adrian Neil Verity Sustained release drug delivery systems and related methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2614864C3 (de) * 1976-04-06 1979-11-29 Schwabe, Willmar, Dr., 7500 Karlsruhe Verfahren zur Herstellung Digoxin enthaltender Arzneipräparate in Weichgelatinekapseln zur oralen Verabfolgung
DE3307353C2 (de) * 1983-03-02 1985-01-31 R.P. Scherer GmbH, 6930 Eberbach Polyethylenglykolhaltige Weichgelatinekapsel und Verfahren zu ihrer Herstellung
JPH0713012B2 (ja) * 1984-02-08 1995-02-15 ア−ル ピ− シ−ラ− コ−ポレ−シヨン アセトアミノフェン・ゼラチンカプセル
GB2185887B (en) * 1987-02-18 1989-12-06 Farmitalia Carlo Erba Ltd Temazepam composition

Also Published As

Publication number Publication date
EP0502042B1 (en) 1995-04-12
GB9025491D0 (en) 1991-01-09
WO1991007950A1 (en) 1991-06-13
AU652924B2 (en) 1994-09-15
PT95991B (pt) 1998-01-30
FI922364L (fi) 1992-05-22
GB2238478A (en) 1991-06-05
DE69018647T2 (de) 1995-08-10
FI922364A7 (fi) 1992-05-22
DE69018647D1 (de) 1995-05-18
NO922005D0 (no) 1992-05-21
EP0502042A1 (en) 1992-09-09
GB2238478B (en) 1993-11-17
DK0502042T3 (da) 1995-06-26
GB8926612D0 (en) 1990-01-17
FI922364A0 (fi) 1992-05-22
PT95991A (pt) 1991-09-13
ZA909426B (en) 1991-09-25
AU6746190A (en) 1991-06-26

Similar Documents

Publication Publication Date Title
NO922005L (no) Farmasoeytiske preparater
FI102142B (fi) Kosmeettinen koostumus, joka käsittää vähintään yhtä aktiivista ainett a sisältäviä, polymeerista tai rasvasta valmistettuja mikropalloja
NO840793L (no) Farmasoeytisk middel
DE3684354D1 (de) Arzneimittel, die hohle, feine, roehrchenfoermige wirkstoffabgabesysteme enthalten.
KR880009639A (ko) 서방성 매트릭스 제형
ATE84032T1 (de) Benzimidazolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
CA2182508A1 (en) Abuse resistant tablets
BE860727A (fr) Nouveaux benzamides trans-n-(2-aminocycloaliphatiques), leur procede de preparation et medicament les contenant
BR9912748A (pt) Cápsula em duas partes para receber preparações farmacêuticas para inaladores de pó
FR2778406B1 (fr) Derives d'alpha-cetoamides, procede pour leur preparation, preparations pharmaceutiques les contenant, et leur utilisation en tant que medicaments anti-viraux
KR870006893A (ko) 고점성 하이드로겔 또는 그 현탁액의 약학적 제제
RU94043798A (ru) Новая диффузионно-осмотическая фармацевтическая композиция с регулируемым выделением лекарства и способ ее получения
KR840003415A (ko) 경구용 당뇨병 치료제의 제조방법
IT1240768B (it) Composizione farmaceutica contenente ranitidina sotto forma di capsule di gelatina.
JPS61501202A (ja) アセトアミノフェン・ゼラチンカプセル
KR850700218A (ko) 약학 조성물
EP0168360A3 (en) Process for preparing etofibrate or similar compounds containing sustained release microgranules and products thus obtained
BE890808A (fr) Nouvelle forme galenique d'administration de metoclopramide, son procede de preparation et medicament comprenant cette nouvelle forme
FR2675802B1 (fr) Antiserotonines, leur preparation et les medicaments les contenant.
FR2719593B1 (fr) Nouveaux polypeptides biologiquement actifs, leur préparation et composition pharmaceutique les contenant.
DE3874390D1 (de) Carboxystyrol-derivate und arzneimittel, die sie als wirkstoff enthalten.
ATE85213T1 (de) Einen wirkstoff und ein in wasser quellendes polymer enthaltendes arzneimittel.
HUP9701112A2 (hu) Antiflatulenst tartalmazó töltőanyag lágy zselatin kapszula gyógyszeradagolási formához
FI843609A7 (fi) Nestemäiset, ionisia aineosia sisältävät farmaseuttiset valmisteet, jotka pidentävät lääkeaineen vapautumista.
RU2302233C2 (ru) Масляные тиксотропные композиции