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NO921159L - Tiazolidinon- og oksazolidinonderivater, fremgangsmaate til fremstilling derav, samt anvendelse av derivatene som vasodilatorer - Google Patents

Tiazolidinon- og oksazolidinonderivater, fremgangsmaate til fremstilling derav, samt anvendelse av derivatene som vasodilatorer

Info

Publication number
NO921159L
NO921159L NO92921159A NO921159A NO921159L NO 921159 L NO921159 L NO 921159L NO 92921159 A NO92921159 A NO 92921159A NO 921159 A NO921159 A NO 921159A NO 921159 L NO921159 L NO 921159L
Authority
NO
Norway
Prior art keywords
derivatives
tiazolidinon
oxsazolidinon
vasodilators
procedures
Prior art date
Application number
NO92921159A
Other languages
English (en)
Other versions
NO921159D0 (no
NO304311B1 (no
Inventor
Sadao Ishihara
Fujio Saito
Takao Yoshioka
Hiroyuki Koike
Sigeki Miyake
Hiroshi Mizuno
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO921159D0 publication Critical patent/NO921159D0/no
Publication of NO921159L publication Critical patent/NO921159L/no
Publication of NO304311B1 publication Critical patent/NO304311B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Indole Compounds (AREA)
NO921159A 1991-03-27 1992-03-25 Tiazolidinon- og oksazolidinonderivater og farmas°ytisk preparat NO304311B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6308891 1991-03-27
JP10275191 1991-05-08
JP33030491 1991-12-13

Publications (3)

Publication Number Publication Date
NO921159D0 NO921159D0 (no) 1992-03-25
NO921159L true NO921159L (no) 1992-09-28
NO304311B1 NO304311B1 (no) 1998-11-30

Family

ID=27298042

Family Applications (1)

Application Number Title Priority Date Filing Date
NO921159A NO304311B1 (no) 1991-03-27 1992-03-25 Tiazolidinon- og oksazolidinonderivater og farmas°ytisk preparat

Country Status (23)

Country Link
US (2) US5298516A (no)
EP (1) EP0506434B1 (no)
JP (1) JPH0780859B2 (no)
KR (1) KR0152097B1 (no)
CN (2) CN1031824C (no)
AT (1) ATE118770T1 (no)
AU (1) AU647599B2 (no)
CA (1) CA2064108C (no)
CZ (1) CZ282529B6 (no)
DE (1) DE69201451T2 (no)
DK (1) DK0506434T3 (no)
ES (1) ES2072095T3 (no)
FI (1) FI106260B (no)
HK (1) HK123595A (no)
HU (2) HU217969B (no)
IE (1) IE67383B1 (no)
IL (1) IL101395A (no)
IS (1) IS1746B (no)
NO (1) NO304311B1 (no)
NZ (1) NZ242154A (no)
PH (1) PH30493A (no)
RU (1) RU2055073C1 (no)
TW (1) TW226015B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3454531B2 (ja) * 1991-11-07 2003-10-06 三共株式会社 ニトロキシアルキルアミド誘導体
EP0689435A1 (de) * 1993-03-15 1996-01-03 Byk Nederland Bv Verwendung von substituierten alkylnitraten zur behandlung des krankhaft erhöhten augeninnendruckes
DE4429461A1 (de) * 1994-08-19 1996-02-22 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten
MX9704435A (es) * 1994-12-15 1997-10-31 Sankyio Company Ltd Compuestos de tiazolidinona y agente terapeutico o agente de prevencion para angina de pecho, que comprende los compuestos como un ingrediente activo.
US5925658A (en) * 1995-03-02 1999-07-20 Sankyo Company, Limited Optically active thiazolidinone derivative
CA2214386C (en) * 1995-03-02 2001-12-04 Sadao Ishihara Optically active thiazolidinone derivatives
AU6016496A (en) * 1995-06-14 1997-01-15 Sankyo Company Limited Antianginal drug comprising nitroxy derivative as active ingredient
BE1010768A3 (nl) * 1996-11-26 1999-01-05 Dsm Nv Een werkwijze voor de bereiding van alpha-aminozuuramiden, alpha-aminozuren en derivaten ervan.
IL120531A (en) 1997-03-26 2006-12-31 Yissum Res Dev Co Nitric oxide donors and pharmaceutical compositions containing them
WO2002069967A1 (en) * 2001-03-01 2002-09-12 Sankyo Company, Limited Percutaneous absorption compositions
EP2736890A4 (en) * 2011-07-28 2015-07-15 Promentis Pharm Inc Cysteine PRODRUGS
US10239847B1 (en) 2016-03-03 2019-03-26 Cellactin Method for 2-oxothiazolidine-4-carboxylic acid for cellular glutathione

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200640A (en) * 1976-04-02 1980-04-29 Chugai Seiyaku Kabushiki Kaisha Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use
GB8717068D0 (en) * 1987-07-20 1987-08-26 Fujisawa Pharmaceutical Co Nitric ester derivative
UA35548C2 (uk) * 1989-04-21 2001-04-16 Е.І. Дюпон Де Немур Енд Компані Похідні оксазолідинону, спосіб їх одержання та фунгіцидна композиція

Also Published As

Publication number Publication date
NZ242154A (en) 1993-09-27
TW226015B (no) 1994-07-01
AU647599B2 (en) 1994-03-24
EP0506434B1 (en) 1995-02-22
CN1066067A (zh) 1992-11-11
CN1096265C (zh) 2002-12-18
CA2064108C (en) 2000-09-26
FI106260B (fi) 2000-12-29
HUT68242A (en) 1995-06-28
CZ91692A3 (en) 1993-01-13
CZ282529B6 (cs) 1997-08-13
DK0506434T3 (da) 1995-07-24
HU9201033D0 (en) 1992-06-29
JPH0780859B2 (ja) 1995-08-30
RU2055073C1 (ru) 1996-02-27
IL101395A (en) 1996-10-16
DE69201451D1 (de) 1995-03-30
CN1031824C (zh) 1996-05-22
JPH05213910A (ja) 1993-08-24
AU1312292A (en) 1992-10-01
NO921159D0 (no) 1992-03-25
CA2064108A1 (en) 1992-09-28
ES2072095T3 (es) 1995-07-01
KR0152097B1 (ko) 1998-10-15
HK123595A (en) 1995-08-04
US5356918A (en) 1994-10-18
FI921340A0 (fi) 1992-03-26
US5298516A (en) 1994-03-29
KR920018036A (ko) 1992-10-21
HU217969B (hu) 2000-05-28
IS3828A (is) 1992-09-28
FI921340L (fi) 1992-09-28
DE69201451T2 (de) 1995-10-12
IL101395A0 (en) 1992-11-15
ATE118770T1 (de) 1995-03-15
NO304311B1 (no) 1998-11-30
IS1746B (is) 2000-07-11
CN1113435A (zh) 1995-12-20
IE920966A1 (en) 1992-10-07
PH30493A (en) 1997-05-28
EP0506434A1 (en) 1992-09-30
HU211969A9 (en) 1996-01-29
IE67383B1 (en) 1996-03-20

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