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NO924034L - COMPOSITION MATERIAL EQUIVALENT FOR LIVE SKIN - Google Patents

COMPOSITION MATERIAL EQUIVALENT FOR LIVE SKIN

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Publication number
NO924034L
NO924034L NO92924034A NO924034A NO924034L NO 924034 L NO924034 L NO 924034L NO 92924034 A NO92924034 A NO 92924034A NO 924034 A NO924034 A NO 924034A NO 924034 L NO924034 L NO 924034L
Authority
NO
Norway
Prior art keywords
skin
type
equivalent
collagen
porous
Prior art date
Application number
NO92924034A
Other languages
Norwegian (no)
Other versions
NO924034D0 (en
Inventor
Mark Eisenberg
Original Assignee
Mark Eisenberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/AU1991/000160 external-priority patent/WO1991016010A1/en
Application filed by Mark Eisenberg filed Critical Mark Eisenberg
Publication of NO924034D0 publication Critical patent/NO924034D0/en
Publication of NO924034L publication Critical patent/NO924034L/en

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  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

En kompositt ekvivalent til levende hud beskrives og omfatter et epidermalt lag dyrkede keratinocyttcelier, et lag ikke-porøst kollagen og et dermalt lag dyrkede fibroblast-celler i en porøs tverrbundet kollagentampong-matrise. Det ikke-porzse kollagen er fcrzrinnsvis type l-, type 3- eller blandinger av type l- og type 3-bovinkollagen, som er pepsin-behandlet. Det beskrives en fremgangsmåte til fremstilling av hudekvivalenten, så vel som en tesrutrustning for in vitro testing av hudekvivalenten. Hudekvivalenten har anvendelse ved hudtransplantasjon, så vel som in viere testing av forskjellige stoffers effekter på hud.A composite equivalent to living skin is described and comprises an epidermal layer of cultured keratinocyte cells, a layer of non-porous collagen and a dermal layer of cultured fibroblast cells in a porous cross-linked collagen tampon matrix. The non-porous collagen is preferably type I, type 3, or mixtures of type 1 and type 3 bovine collagen, which are pepsin-treated. There is disclosed a method for producing the skin equivalent as well as a test equipment for in vitro testing of the skin equivalent. The skin equivalent has application in skin transplantation as well as in-depth testing of the effects of various substances on skin.

NO92924034A 1990-03-02 1992-10-19 COMPOSITION MATERIAL EQUIVALENT FOR LIVE SKIN NO924034L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPJ891990 1990-03-02
AUPK430291 1991-01-22
PCT/AU1991/000160 WO1991016010A1 (en) 1990-04-24 1991-04-24 Composite living skin equivalents

Publications (2)

Publication Number Publication Date
NO924034D0 NO924034D0 (en) 1992-10-19
NO924034L true NO924034L (en) 1992-10-22

Family

ID=27156821

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92924034A NO924034L (en) 1990-03-02 1992-10-19 COMPOSITION MATERIAL EQUIVALENT FOR LIVE SKIN

Country Status (1)

Country Link
NO (1) NO924034L (en)

Also Published As

Publication number Publication date
NO924034D0 (en) 1992-10-19

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