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NO913008L - Fremgangsmaate for fremstilling av fenylacetamid-derivater. - Google Patents

Fremgangsmaate for fremstilling av fenylacetamid-derivater.

Info

Publication number
NO913008L
NO913008L NO91913008A NO913008A NO913008L NO 913008 L NO913008 L NO 913008L NO 91913008 A NO91913008 A NO 91913008A NO 913008 A NO913008 A NO 913008A NO 913008 L NO913008 L NO 913008L
Authority
NO
Norway
Prior art keywords
procedure
preparation
phenylacetamide derivatives
phenylacetamide
derivatives
Prior art date
Application number
NO91913008A
Other languages
English (en)
Other versions
NO175528C (no
NO913008D0 (no
NO175528B (no
Inventor
David Robert Brittain
Steven Paul Brown
Anthony Loren Cooper
Jethro Lawrence Longridge
Jeffrey James Morris
John Preston
Linda Slater
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10680064&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO913008(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ici Plc filed Critical Ici Plc
Publication of NO913008D0 publication Critical patent/NO913008D0/no
Publication of NO913008L publication Critical patent/NO913008L/no
Publication of NO175528B publication Critical patent/NO175528B/no
Publication of NO175528C publication Critical patent/NO175528C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/26Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/26Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C07C317/40Y being a hydrogen or a carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02Sulfinic acids; Derivatives thereof
    • C07C313/04Sulfinic acids; Esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40Y being a hydrogen or a carbon atom
    • C07C323/41Y being a hydrogen or an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO913008A 1990-08-02 1991-08-01 Analogifremgangsmåte for fremstilling av terapeutisk aktive fenylacetamid-derivater NO175528C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909016978A GB9016978D0 (en) 1990-08-02 1990-08-02 Acetamide derivatives

Publications (4)

Publication Number Publication Date
NO913008D0 NO913008D0 (no) 1991-08-01
NO913008L true NO913008L (no) 1992-02-03
NO175528B NO175528B (no) 1994-07-18
NO175528C NO175528C (no) 1994-10-26

Family

ID=10680064

Family Applications (1)

Application Number Title Priority Date Filing Date
NO913008A NO175528C (no) 1990-08-02 1991-08-01 Analogifremgangsmåte for fremstilling av terapeutisk aktive fenylacetamid-derivater

Country Status (32)

Country Link
US (2) US5270342A (no)
EP (1) EP0469887B1 (no)
JP (1) JP2930452B2 (no)
KR (1) KR920004342A (no)
CN (1) CN1036389C (no)
AP (1) AP261A (no)
AT (1) ATE115560T1 (no)
AU (1) AU646273B2 (no)
BG (1) BG60316B2 (no)
CA (1) CA2048325A1 (no)
CZ (1) CZ280642B6 (no)
DE (1) DE69105856T2 (no)
DK (1) DK0469887T3 (no)
ES (1) ES2067874T3 (no)
FI (1) FI913706A7 (no)
GB (2) GB9016978D0 (no)
HR (1) HRP931326B1 (no)
HU (2) HU210057B (no)
IE (1) IE65870B1 (no)
IL (1) IL98908A (no)
JO (1) JO1696B1 (no)
MY (1) MY109594A (no)
NO (1) NO175528C (no)
NZ (1) NZ239124A (no)
PH (1) PH31572A (no)
PL (2) PL166392B1 (no)
PT (1) PT98529B (no)
RO (1) RO109645B1 (no)
RU (1) RU2068409C1 (no)
SI (1) SI9111318A (no)
YU (1) YU131891A (no)
ZA (1) ZA915783B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9016984D0 (en) * 1990-08-02 1990-09-19 Ici Plc Aniline derivatives
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives
KR0147963B1 (ko) * 1995-01-10 1998-08-17 강박광 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법
FR2757509B1 (fr) 1996-12-23 1999-03-26 Lipha Nouveaux derives de sulfonamides et sulfonylurees, leurs preparations et medicaments les contenant
CN101239089A (zh) * 1997-04-15 2008-08-13 Csir公司 具有食欲抑制剂活性的药物组合物
US5932765A (en) * 1997-05-23 1999-08-03 Merck Patent Gesellschaft Mit Nitromethyl ketones, process for preparing them and compositions containing them
GB9714274D0 (en) 1997-07-08 1997-09-10 Zeneca Ltd Pharmaceutical composition
CZ299018B6 (cs) * 1997-10-20 2008-04-02 Dainippon Sumitomo Pharma Co., Ltd. Rychlerozpustný farmaceutický prípravek
CA2819705C (en) 1998-02-02 2014-07-08 Trustees Of Tufts College Method of regulating glucose metabolism, and reagents related thereto
ATE250418T1 (de) * 1998-07-15 2003-10-15 Merck Sante Sas Tabletten enthaltend eine kombination von glibenclamid und metformin
GB2396815B (en) * 1999-10-27 2004-09-08 Phytopharm Plc A composition comprising a pregnenone derivative and an NSAID
GB2363985B (en) 2000-06-30 2004-09-29 Phytopharm Plc Extracts,compounds & pharmaceutical compositions having anti-diabetic activity and their use
CN1477976A (zh) 2000-11-30 2004-02-25 �Ʒ� Gaba激动剂与醛糖还原酶抑制剂的组合
RU2191012C1 (ru) * 2001-06-20 2002-10-20 Научно-исследовательский испытательный центр (медико-биологической защиты) Государственного научно-исследовательского испытательного института военной медицины МО РФ Глазные капли для лечения эндотелиально-эпителиальной дистрофии роговицы
US20110092566A1 (en) * 2004-11-19 2011-04-21 Srivastava Satish K Treatment of cancer with aldose reductase inhibitors
JP5042843B2 (ja) * 2005-04-28 2012-10-03 白鳥製薬株式会社 ヒドラゾン類の製造法
US7671221B2 (en) * 2005-12-28 2010-03-02 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
ES2398319T3 (es) * 2005-12-28 2013-03-15 Vertex Pharmaceuticals Incorporated Derivados de 1-(benzo[D][1,3]dioxol-5-il)-N-(fenil)ciclopropano-carboxamida y compuestos relacionados como moduladores de transportadores de casetes de unión a ATP para el tratamiento de la fibrosis quística
ATE518544T1 (de) 2007-03-12 2011-08-15 Zadec Aps Rotbusch-extrakt gegen diabetes
US8273746B2 (en) * 2007-03-23 2012-09-25 The Board Of Regents Of The University Of Texas System Methods involving aldose reductase inhibitors
FR2914188B1 (fr) * 2007-03-28 2012-06-22 Trophos Nouvelle composition a base d'oxime de cholest-4-en-3-one
US20090270490A1 (en) * 2008-04-24 2009-10-29 The Board Of Regents Of The University Of Texas System Methods involving aldose reductase inhibition
WO2012088525A2 (en) 2010-12-23 2012-06-28 The Board Of Regents Of The University Of Texas System Methods for treating copd
US12090142B2 (en) 2018-02-22 2024-09-17 Board Of Regents, The University Of Texas System Combination therapy for the treatment of cancer

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1229653A (no) * 1968-03-14 1971-04-28
US3882247A (en) * 1972-04-21 1975-05-06 Du Pont Fungicidal nitro organic sulfur compounds
SU479761A1 (ru) * 1973-07-18 1975-08-05 Институт Органической Химии Им. Н.Д.Зелинского Ан Ссср Способ получени -динитроалкилсульфонов
US4053633A (en) * 1976-06-24 1977-10-11 The Dow Chemical Company Aryl dibromonitromethyl sulfones
US4058633A (en) * 1976-09-15 1977-11-15 Fairmont Foods Company Meat product, and process for preparing same
FR2432316A1 (fr) * 1978-08-02 1980-02-29 Choay Sa Nouveaux medicaments contenant, a titre de substance active, des composes de type benzenesulfone, nouveaux composes de ce type et procede pour leur preparation
US4670470A (en) * 1979-08-15 1987-06-02 Merck & Co., Inc. Allylsulfoxide enzyme inhibitors
US4309554A (en) * 1980-04-28 1982-01-05 The Dow Chemical Company 3-(2-Thiophenesulfonyl)-2-halopropanenitriles
JPS5740478A (en) * 1980-08-22 1982-03-06 Ono Pharmaceut Co Ltd Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative
DE3326635A1 (de) * 1983-07-23 1985-01-31 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von monomethylsubstituierten methylen-verbindungen
EP0169887B1 (en) * 1984-02-01 1990-06-27 BAXTER INTERNATIONAL INC. (a Delaware corporation) Clinical analysis systems and methods
EP0252640B1 (en) * 1986-06-30 1991-03-06 Merck & Co. Inc. Alkanesulfonamides as antiglaucoma agents
GB8718619D0 (en) * 1987-08-06 1987-09-09 Ici Plc Pharmaceutical compositions
GB8810203D0 (en) * 1988-04-29 1988-06-02 Ici Plc Heterocyclic compounds
IE63463B1 (en) * 1989-02-06 1995-04-19 Zeneca Ltd Phenylsulphone derivatives
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives

Also Published As

Publication number Publication date
NO175528C (no) 1994-10-26
PT98529B (pt) 1999-01-29
BG60316B2 (bg) 1994-07-25
AU646273B2 (en) 1994-02-17
PL168026B1 (pl) 1995-12-30
DE69105856D1 (de) 1995-01-26
NO913008D0 (no) 1991-08-01
ZA915783B (en) 1992-05-27
PH31572A (en) 1998-11-03
JO1696B1 (en) 1992-12-15
HU210057B (en) 1995-01-30
HRP931326B1 (en) 1998-06-30
IL98908A0 (en) 1992-07-15
HU210883A9 (en) 1995-09-28
IL98908A (en) 1995-03-30
AU8123391A (en) 1992-02-06
PT98529A (pt) 1992-06-30
RU2068409C1 (ru) 1996-10-27
GB9016978D0 (en) 1990-09-19
JPH04234356A (ja) 1992-08-24
ATE115560T1 (de) 1994-12-15
RO109645B1 (ro) 1995-04-28
NO175528B (no) 1994-07-18
EP0469887B1 (en) 1994-12-14
US5430060A (en) 1995-07-04
FI913706A0 (fi) 1991-08-02
PL166392B1 (pl) 1995-05-31
HU912482D0 (en) 1991-12-30
CS232791A3 (en) 1992-03-18
ES2067874T3 (es) 1995-04-01
HRP931326A2 (en) 1996-04-30
DE69105856T2 (de) 1995-05-11
FI913706A7 (fi) 1992-02-03
GB2247678A (en) 1992-03-11
JP2930452B2 (ja) 1999-08-03
HK1000965A1 (en) 1998-05-15
CZ280642B6 (cs) 1996-03-13
GB2247678B (en) 1994-07-27
GB9115254D0 (en) 1991-08-28
YU131891A (sh) 1994-06-10
AP261A (en) 1993-06-03
DK0469887T3 (da) 1995-04-03
HUT59088A (en) 1992-04-28
CN1059517A (zh) 1992-03-18
IE912529A1 (en) 1992-02-12
CN1036389C (zh) 1997-11-12
US5270342A (en) 1993-12-14
KR920004342A (ko) 1992-03-27
AP9100306A0 (en) 1991-07-31
EP0469887A1 (en) 1992-02-05
NZ239124A (en) 1994-04-27
IE65870B1 (en) 1995-11-29
MY109594A (en) 1997-03-31
PL291312A1 (en) 1992-09-21
SI9111318A (en) 1997-10-31
CA2048325A1 (en) 1992-02-03

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