NO910878L - 2-oxabicyclo(2.2.1)heptanderivater og legemidler inneholdende disse forbindelser. - Google Patents

2-oxabicyclo(2.2.1)heptanderivater og legemidler inneholdende disse forbindelser.

Info

Publication number: NO910878L
Authority: NO; Norway
Prior art keywords: compounds; 3bond; pct; group; image
Prior art date: 1988-09-07

Application number

NO91910878A

Other languages

English (en)

Other versions

NO177994B (no

NO177994C (no

NO910878D0 (no

Inventor

Ulrich Klar

Helmut Vorbrueggen

Hartmut Rehwinkel

Karl-Heinz Thierauch

Claus-Steffen Stuerzebecher

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-07

Filing date

1991-03-06

Publication date

1991-05-06

1991-03-06 Application filed by Schering Ag filed Critical Schering Ag

1991-03-06 Publication of NO910878D0 publication Critical patent/NO910878D0/no

1991-05-06 Publication of NO910878L publication Critical patent/NO910878L/no

1995-09-25 Publication of NO177994B publication Critical patent/NO177994B/no

1996-01-03 Publication of NO177994C publication Critical patent/NO177994C/no

Links

150000001875 compounds Chemical class 0.000 title abstract 4
JLVDVIXDYDGVLS-UHFFFAOYSA-N 3-oxabicyclo[2.2.1]heptane Chemical class C1C2CCC1OC2 JLVDVIXDYDGVLS-UHFFFAOYSA-N 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 2
-1 -OR2 Chemical class 0.000 abstract 2
229920000858 Cyclodextrin Polymers 0.000 abstract 2
125000002947 alkylene group Chemical group 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
229920001450 Alpha-Cyclodextrin Polymers 0.000 abstract 1
HFHDHCJBZVLPGP-RWMJIURBSA-N alpha-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO HFHDHCJBZVLPGP-RWMJIURBSA-N 0.000 abstract 1
229940043377 alpha-cyclodextrin Drugs 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 abstract 1
229960004853 betadex Drugs 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
GDSRMADSINPKSL-HSEONFRVSA-N gamma-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO GDSRMADSINPKSL-HSEONFRVSA-N 0.000 abstract 1
229940080345 gamma-cyclodextrin Drugs 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000002502 liposome Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
239000008177 pharmaceutical agent Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Furan Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

NO910878A 1988-09-07 1991-03-06 Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-oksabicyklo[2,2,1Åheptanderivater NO177994C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3830878A DE3830878A1 (de)	1988-09-07	1988-09-07	2-oxa-bicyclo(2.2.1)heptanderivate und diese verbindungen enthaltende arzneimittel
PCT/DE1989/000585 WO1990002740A1 (de)	1988-09-07	1989-09-07	2-oxa-bicyclo[2.2.1]heptanderivate und diese verbindungen enthaltende arzneimittel

Publications (4)

Publication Number	Publication Date
NO910878D0 NO910878D0 (no)	1991-03-06
NO910878L true NO910878L (no)	1991-05-06
NO177994B NO177994B (no)	1995-09-25
NO177994C NO177994C (no)	1996-01-03

Family

ID=6362727

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO910878A NO177994C (no)	1988-09-07	1991-03-06	Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-oksabicyklo[2,2,1Åheptanderivater

Country Status (12)

Country	Link
US (1)	US5235072A (no)
EP (1)	EP0358290B1 (no)
JP (1)	JPH04500204A (no)
AT (1)	ATE85332T1 (no)
AU (1)	AU642395B2 (no)
DE (2)	DE3830878A1 (no)
DK (1)	DK40991D0 (no)
ES (1)	ES2053965T3 (no)
GR (1)	GR3007296T3 (no)
HU (1)	HUT58712A (no)
NO (1)	NO177994C (no)
WO (1)	WO1990002740A1 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19522029A1 (de) *	1995-06-17	1996-12-19	Uestra Hannoversche Verkehrsbe	Vorrichtung zum Lesen und/oder Schreiben von Speicherkarten
DE19608316C2 (de) *	1996-02-22	2000-11-09	Ivoclar Ag Schaan	Funktionalisierte bicyclische (Meth)acrylate, Verfahren zu deren Herstellung und deren Verwendung ####
CN115746072B (zh) *	2022-11-14	2024-10-18	杭州新曦科技有限公司	一种克拉霉素的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3950363A (en) *	1975-03-10	1976-04-13	The Upjohn Company	Prostaglandin cyclic ethers
US4028350A (en) *	1976-06-25	1977-06-07	The Upjohn Company	9α,11αOR 11α,9αEpoxymethano-prostaglandans and process for their preparation
JPS5927345B2 (ja) *	1980-02-07	1984-07-05	理化学研究所	光学活性シクロペンタン化合物及びその製造法
US4606753A (en) *	1984-06-15	1986-08-19	Shell Oil Company	4-substituted-2-oxabicyclo[2.2.1]heptane ether herbicides

1988
- 1988-09-07 DE DE3830878A patent/DE3830878A1/de not_active Withdrawn
1989
- 1989-09-07 US US07/679,054 patent/US5235072A/en not_active Expired - Fee Related
- 1989-09-07 ES ES89250031T patent/ES2053965T3/es not_active Expired - Lifetime
- 1989-09-07 AT AT89250031T patent/ATE85332T1/de not_active IP Right Cessation
- 1989-09-07 DE DE8989250031T patent/DE58903440D1/de not_active Expired - Fee Related
- 1989-09-07 AU AU41953/89A patent/AU642395B2/en not_active Ceased
- 1989-09-07 JP JP1509176A patent/JPH04500204A/ja active Pending
- 1989-09-07 HU HU896000A patent/HUT58712A/hu unknown
- 1989-09-07 WO PCT/DE1989/000585 patent/WO1990002740A1/de not_active Ceased
- 1989-09-07 EP EP89250031A patent/EP0358290B1/de not_active Expired - Lifetime
1991
- 1991-03-06 NO NO910878A patent/NO177994C/no unknown
- 1991-03-07 DK DK91409A patent/DK40991D0/da not_active Application Discontinuation
1993
- 1993-03-09 GR GR930400522T patent/GR3007296T3/el unknown

Also Published As

Publication number	Publication date
EP0358290A1 (de)	1990-03-14
DK40991A (da)	1991-03-07
GR3007296T3 (no)	1993-07-30
NO177994B (no)	1995-09-25
US5235072A (en)	1993-08-10
AU4195389A (en)	1990-04-02
JPH04500204A (ja)	1992-01-16
AU642395B2 (en)	1993-10-21
WO1990002740A1 (de)	1990-03-22
HUT58712A (en)	1992-03-30
NO177994C (no)	1996-01-03
NO910878D0 (no)	1991-03-06
DE58903440D1 (de)	1993-03-18
ATE85332T1 (de)	1993-02-15
ES2053965T3 (es)	1994-08-01
HU896000D0 (en)	1991-07-29
EP0358290B1 (de)	1993-02-03
DK40991D0 (da)	1991-03-07
DE3830878A1 (de)	1990-03-08

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