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NO910444L - Alkoksy-4(1h)-pyridonderivater, fremgangsmaater for fremstilling derav og deres anvendelse som legemiddel. - Google Patents

Alkoksy-4(1h)-pyridonderivater, fremgangsmaater for fremstilling derav og deres anvendelse som legemiddel.

Info

Publication number
NO910444L
NO910444L NO91910444A NO910444A NO910444L NO 910444 L NO910444 L NO 910444L NO 91910444 A NO91910444 A NO 91910444A NO 910444 A NO910444 A NO 910444A NO 910444 L NO910444 L NO 910444L
Authority
NO
Norway
Prior art keywords
alkoxy
medicine
procedures
production
pyridone derivatives
Prior art date
Application number
NO91910444A
Other languages
English (en)
Other versions
NO177785B (no
NO177785C (no
NO910444D0 (no
Inventor
Julian Aranda
Johannes Hartenstein
Reinhard Reck
Christoph Schaechtele
Claus Rudolph
Hartmut Osswald
Guenter Weinheimer
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of NO910444L publication Critical patent/NO910444L/no
Publication of NO910444D0 publication Critical patent/NO910444D0/no
Publication of NO177785B publication Critical patent/NO177785B/no
Publication of NO177785C publication Critical patent/NO177785C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO910444A 1988-08-06 1991-02-05 Analogifremgangsmåter for fremstilling av terapeutisk aktive alkoksy-4(1H)-pyridonderivater NO177785C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3826846A DE3826846A1 (de) 1988-08-06 1988-08-06 Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
PCT/EP1989/000927 WO1990001477A1 (de) 1988-08-06 1989-08-04 Alkoxy-4(1h)-pyridon-derivative, verfahren zu deren herstellung und deren verwendung als arzneimittel

Publications (4)

Publication Number Publication Date
NO910444L true NO910444L (no) 1991-02-05
NO910444D0 NO910444D0 (no) 1991-02-05
NO177785B NO177785B (no) 1995-08-14
NO177785C NO177785C (no) 1995-11-22

Family

ID=6360419

Family Applications (1)

Application Number Title Priority Date Filing Date
NO910444A NO177785C (no) 1988-08-06 1991-02-05 Analogifremgangsmåter for fremstilling av terapeutisk aktive alkoksy-4(1H)-pyridonderivater

Country Status (18)

Country Link
US (2) US5185352A (no)
EP (2) EP0427765B1 (no)
JP (1) JP2878361B2 (no)
KR (1) KR920006779B1 (no)
CN (1) CN1040193A (no)
AT (1) ATE188469T1 (no)
AU (1) AU627766B2 (no)
CA (1) CA1340608C (no)
DD (1) DD284003A5 (no)
DE (2) DE3826846A1 (no)
DK (1) DK174097B1 (no)
ES (1) ES2144391T3 (no)
GR (1) GR3033072T3 (no)
HU (1) HUT56545A (no)
NO (1) NO177785C (no)
PT (1) PT91351B (no)
WO (1) WO1990001477A1 (no)
ZA (1) ZA895969B (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283404C (en) * 1986-07-01 1991-04-23 Shigeru Sanai Cephalosporin compounds, processes for their preparation and antibacterial agents
DE3826846A1 (de) * 1988-08-06 1990-02-08 Goedecke Ag Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
FR2687674B1 (fr) * 1992-02-07 1995-05-19 Roussel Uclaf Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US5674883A (en) * 1992-02-07 1997-10-07 Roussel Uclaf Derivatives of pyridone, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them
DE4243321A1 (de) * 1992-12-21 1994-06-23 Goedecke Ag Aminosäurederivate von Heterocyclen als PKC-Inhibitoren
US6046219A (en) * 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5849587A (en) * 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
JP2002531512A (ja) * 1998-12-07 2002-09-24 エコスマート テクノロジーズ,インコーポレーテッド 天然植物精油を用いた癌治療薬配合物および方法
US6867217B1 (en) 1999-05-19 2005-03-15 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade
US6906068B1 (en) 1999-05-19 2005-06-14 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl 1,2,4 - triazinones useful as anticoagulants
US6750342B1 (en) 1999-05-19 2004-06-15 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
US6664255B1 (en) 1999-05-19 2003-12-16 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
US6653316B1 (en) 1999-05-19 2003-11-25 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
US6716838B1 (en) 1999-05-19 2004-04-06 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents
US7015230B1 (en) 1999-05-19 2006-03-21 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade
WO2001068605A1 (en) 2000-03-13 2001-09-20 Pharmacia Corporation Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade
WO2001077097A2 (en) 2000-04-05 2001-10-18 Pharmacia Corporation Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade
CA2405306A1 (en) 2000-04-05 2001-10-18 Pharmacia Corporation Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the coagulation cascade
US7119094B1 (en) 2000-11-20 2006-10-10 Warner-Lambert Company Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade
US7015223B1 (en) 2000-11-20 2006-03-21 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl 1,2,4-triazinones useful for selective inhibition of the coagulation cascade
CA2430037A1 (en) 2000-11-20 2002-05-30 Michael S. South Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade
BR0213092A (pt) 2001-10-03 2004-10-19 Pharmacia Corp Compostos heterocìclicos de 6 elementos úteis para a inibição seletiva da cascata de coagulação
US7105559B2 (en) 2001-10-03 2006-09-12 Pharmacia Corporation Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade
CA2627529A1 (en) 2007-03-28 2008-09-28 Apotex Technologies Inc. Fluorinated derivatives of deferiprone
BRPI0822206B8 (pt) 2008-04-25 2021-05-25 Apotex Tech Inc formulação líquida para deferiprona com um sabor agradável.
BRPI1007636A2 (pt) 2009-05-01 2015-09-01 Aptalis Pharmatech Inc Composição farmacêutica, forma de dosagem, método para a preparação da composição farmacêutica, método de preparação da forma de dosagem e método de tratamento da dor
EP2448922B1 (en) * 2009-07-03 2014-08-20 Apotex Technologies Inc. Fluorinated derivatives of 3-hydroxypyridin-4-ones
CN107709299B (zh) 2015-04-24 2021-07-16 盐野义制药株式会社 6元杂环衍生物及含有其的药物组合物
JP6692113B2 (ja) * 2016-10-21 2020-05-13 塩野義製薬株式会社 6員複素環誘導体を含有する医薬組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA554715A (en) * 1958-03-18 Boesch Roger Ethers and thioethers and processes for their preparation
US2965641A (en) * 1959-07-06 1960-12-20 Searle & Co Derivatives of 1-(2-aminoethyl)-5-alkoxy-4-pyridones
CA978958A (en) * 1971-10-04 1975-12-02 Haydn W.R. Williams Substituted pyranones and -pyridones and process of manufacture
JPS59110675A (ja) * 1982-12-16 1984-06-26 Ss Pharmaceut Co Ltd ピリジン誘導体及びその製造方法
JPS59110674A (ja) * 1982-12-16 1984-06-26 Ss Pharmaceut Co Ltd ピリジン誘導体及びその製造法
GB8308055D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
CA1283404C (en) * 1986-07-01 1991-04-23 Shigeru Sanai Cephalosporin compounds, processes for their preparation and antibacterial agents
DE3826846A1 (de) * 1988-08-06 1990-02-08 Goedecke Ag Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel

Also Published As

Publication number Publication date
KR920006779B1 (ko) 1992-08-17
AU4048989A (en) 1990-03-05
NO177785B (no) 1995-08-14
DD284003A5 (de) 1990-10-31
EP0354495A1 (de) 1990-02-14
DK174097B1 (da) 2002-06-10
HU894581D0 (en) 1991-07-29
JPH04500958A (ja) 1992-02-20
DE58909865D1 (de) 2000-02-10
DK11391D0 (da) 1991-01-23
ATE188469T1 (de) 2000-01-15
NO177785C (no) 1995-11-22
EP0427765A1 (de) 1991-05-22
CN1040193A (zh) 1990-03-07
ES2144391T3 (es) 2000-06-16
CA1340608C (en) 1999-06-22
WO1990001477A1 (de) 1990-02-22
KR900701755A (ko) 1990-12-04
US5185352A (en) 1993-02-09
NO910444D0 (no) 1991-02-05
PT91351A (pt) 1990-03-08
JP2878361B2 (ja) 1999-04-05
HUT56545A (en) 1991-09-30
DK11391A (da) 1991-01-23
PT91351B (pt) 1997-01-31
AU627766B2 (en) 1992-09-03
ZA895969B (en) 1990-05-30
DE3826846A1 (de) 1990-02-08
GR3033072T3 (en) 2000-08-31
EP0427765B1 (de) 2000-01-05
US5322844A (en) 1994-06-21

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