[go: up one dir, main page]

NO914085L - Hepatospesifikke insulinanaloger - Google Patents

Hepatospesifikke insulinanaloger

Info

Publication number
NO914085L
NO914085L NO91914085A NO914085A NO914085L NO 914085 L NO914085 L NO 914085L NO 91914085 A NO91914085 A NO 91914085A NO 914085 A NO914085 A NO 914085A NO 914085 L NO914085 L NO 914085L
Authority
NO
Norway
Prior art keywords
hepatospecific
insulin analogs
insulin analogues
hepatospecific insulin
insulin
Prior art date
Application number
NO91914085A
Other languages
English (en)
Other versions
NO914085D0 (no
NO301544B1 (no
Inventor
Panayotis Katsoyannis
Original Assignee
Sinai School Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinai School Medicine filed Critical Sinai School Medicine
Publication of NO914085D0 publication Critical patent/NO914085D0/no
Publication of NO914085L publication Critical patent/NO914085L/no
Publication of NO301544B1 publication Critical patent/NO301544B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
NO914085A 1989-04-20 1991-10-17 Analogifremgangsmåte for fremstilling av en insulinanalog NO301544B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34092989A 1989-04-20 1989-04-20
PCT/US1990/002070 WO1990012814A1 (en) 1989-04-20 1990-04-17 Hepatospecific insulin analogues

Publications (3)

Publication Number Publication Date
NO914085D0 NO914085D0 (no) 1991-10-17
NO914085L true NO914085L (no) 1991-11-28
NO301544B1 NO301544B1 (no) 1997-11-10

Family

ID=23335524

Family Applications (1)

Application Number Title Priority Date Filing Date
NO914085A NO301544B1 (no) 1989-04-20 1991-10-17 Analogifremgangsmåte for fremstilling av en insulinanalog

Country Status (15)

Country Link
EP (1) EP0469084B1 (no)
JP (1) JPH04504858A (no)
AT (1) ATE120762T1 (no)
AU (1) AU631868B2 (no)
CA (1) CA2014896A1 (no)
DE (1) DE69018461T2 (no)
FI (1) FI914898A7 (no)
GR (1) GR1000908B (no)
HU (1) HU210142B (no)
IE (1) IE67353B1 (no)
IL (1) IL94163A (no)
NO (1) NO301544B1 (no)
PT (1) PT93832B (no)
WO (1) WO1990012814A1 (no)
ZA (1) ZA902965B (no)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK158390D0 (da) * 1990-07-02 1990-07-02 Novo Nordisk As Nye peptider
DK33591D0 (no) * 1991-02-27 1991-02-27 Novo Nordisk As
US5268453A (en) * 1991-08-08 1993-12-07 Scios Inc. Tissue-selective insulin analogs
GB9316895D0 (en) * 1993-08-13 1993-09-29 Guy S And St Thomas Hospitals Hepatoselective insulin analogues
US5915378A (en) * 1993-01-29 1999-06-29 Aradigm Corporation Creating an aerosolized formulation of insulin
US5873358A (en) * 1993-01-29 1999-02-23 Aradigm Corporation Method of maintaining a diabetic patient's blood glucose level in a desired range
US5743250A (en) * 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
US5888477A (en) 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US7448375B2 (en) 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US5970973A (en) * 1993-01-29 1999-10-26 Aradigm Corporation Method of delivering insulin lispro
US6131567A (en) * 1993-01-29 2000-10-17 Aradigm Corporation Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin
TW360548B (en) * 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
US6342225B1 (en) 1993-08-13 2002-01-29 Deutshces Wollforschungsinstitut Pharmaceutical active conjugates
US6933272B1 (en) 1998-09-22 2005-08-23 Erik Helmerhorst Use of non-peptidyl compounds for the treatment of insulin related ailments
AUPP609198A0 (en) * 1998-09-22 1998-10-15 Curtin University Of Technology Use of non-peptidyl compounds for the treatment of insulin related ailments
KR100679878B1 (ko) * 1999-04-26 2007-02-07 아지노모토 가부시키가이샤 멜라노사이트-자극 호르몬 억제제
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
EP1790654B1 (en) * 2004-08-18 2009-06-17 Kaneka Corporation Peptide capable of binding to insulin-binding protein and adsorbent
ES2368500T3 (es) 2005-08-16 2011-11-17 Novo Nordisk A/S Método para producir polipéptidos de insulina maduros.
JP5864834B2 (ja) 2006-09-22 2016-02-17 ノボ・ノルデイスク・エー／エス プロテアーゼ耐性のインスリンアナログ
JP5503968B2 (ja) 2006-09-27 2014-05-28 ノボ・ノルデイスク・エー／エス 成熟インスリンポリペプチドの作製方法
CN101983066B (zh) 2008-01-30 2016-06-29 印第安那大学科技研究公司 基于酯的胰岛素前药
US9260502B2 (en) 2008-03-14 2016-02-16 Novo Nordisk A/S Protease-stabilized insulin analogues
CN102037008B (zh) 2008-03-18 2016-08-31 诺沃-诺迪斯克有限公司 蛋白酶稳定化的、酰化胰岛素类似物
CN102245633A (zh) * 2008-12-09 2011-11-16 诺沃—诺迪斯克有限公司 新的胰岛素类似物
WO2010080606A1 (en) 2008-12-19 2010-07-15 Indiana University Research And Technology Corporation Insulin analogs
AU2009335715B2 (en) * 2008-12-19 2016-09-15 Indiana University Research And Technology Corporation Amide-based insulin prodrugs
EP2582719B1 (en) 2010-06-16 2016-08-10 Indiana University Research and Technology Corporation Single chain insulin agonists exhibiting high activity at the insulin receptor
WO2011163462A2 (en) 2010-06-24 2011-12-29 Indiana University Research And Technology Corporation Amide-based insulin prodrugs
EP2793932B1 (en) 2011-12-20 2018-10-03 Indiana University Research and Technology Corporation Ctp-based insulin analogs for treatment of diabetes
EP3395358B1 (en) 2012-09-26 2019-11-06 Indiana University Research and Technology Corporation Insulin analog dimers
KR20150131213A (ko) 2013-03-14 2015-11-24 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 인슐린-인크레틴 접합체들
EP2970124B1 (en) 2013-03-14 2019-05-22 The Board of Trustees of the Leland Stanford Junior University Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof
HUE036702T2 (hu) 2013-10-07 2018-07-30 Novo Nordisk As Inzulinanalóg új származéka
US10385107B2 (en) 2014-09-24 2019-08-20 Indiana Univeresity Researc and Technology Corporation Lipidated amide-based insulin prodrugs
US10232020B2 (en) 2014-09-24 2019-03-19 Indiana University Research And Technology Corporation Incretin-insulin conjugates
HUE055231T2 (hu) 2016-12-16 2021-11-29 Novo Nordisk As Inzulint tartalmazó gyógyászati készítmények

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation

Also Published As

Publication number Publication date
GR900100290A (en) 1991-09-27
IE67353B1 (en) 1996-03-20
PT93832A (pt) 1990-11-20
FI914898A0 (fi) 1991-10-17
HUT59941A (en) 1992-07-28
DE69018461T2 (de) 1995-08-03
DE69018461D1 (de) 1995-05-11
JPH04504858A (ja) 1992-08-27
ATE120762T1 (de) 1995-04-15
HU210142B (en) 1995-02-28
NO914085D0 (no) 1991-10-17
CA2014896A1 (en) 1990-10-20
GR1000908B (el) 1993-03-16
PT93832B (pt) 1996-09-30
HU903398D0 (en) 1991-12-30
EP0469084B1 (en) 1995-04-05
EP0469084A1 (en) 1992-02-05
AU5541590A (en) 1990-11-16
AU631868B2 (en) 1992-12-10
IL94163A0 (en) 1991-01-31
IL94163A (en) 1995-08-31
ZA902965B (en) 1991-02-27
NO301544B1 (no) 1997-11-10
FI914898A7 (fi) 1991-10-17
WO1990012814A1 (en) 1990-11-01
IE901404L (en) 1990-10-20

Similar Documents

Publication Publication Date Title
NO914085L (no) Hepatospesifikke insulinanaloger
ES552093A0 (es) Un procedimiento para sintetizar una secuencia de aminoacidos que contienen la totalidad o parte de la secuencia de aminoacidos de la preprorrelaxina -h2 humana.
AP2000001888A0 (en) Method for treatment of diabetes using peptides analogues of insulin.
AU6916187A (en) Pharmaceutical compositions containing 3-hydroxybutanoic acid or a salt derived from this acid
ATE266043T1 (de) Peptidanaloge des menschlichen basischen myelinproteins
DE69525544D1 (de) Peptidanaloge des menschlichen, basischen myelinproteins mit substitution an position 91 zur behandlung der multiplen sklerose
AU1971988A (en) Pharmaceutical compositions for the treatment of uraemia
MX167236B (es) Peptidos sinteticos de timosina -1 y metodo para su obtencion
ES2056431T3 (es) Procedimiento para la produccion de r(+)-aminocarnitina y s(-)-aminocarnitina.
ES2189346T3 (es) Metalopeptido aislado: composiciones y procedimientos de sintesis.
SE7501342L (no)
AR026068A1 (es) Peptidos modificados y peptidomimeticos para el uso en inmunoterapia.
PT78046B (de) Cyclische peptide mit somatostatin-wirkung
ATE92078T1 (de) Pharmakologisch aktive peptide.
DK0717048T3 (da) Cyclohexapeptider og deres blandinger, fremgangsmåde til fremstilling deraf samt deres anvendelse
PT99850A (pt) Processo para a preparacao de novos peptideos com efeito insulinico
ATE98962T1 (de) Menschliche rhinoviruspeptide.
ATE137487T1 (de) Komplexe, enthaltend s(+)-phenyl-alkansäuren und alpha-hydroxy-alkansäuren
DK0423326T3 (da) Hidtil ukendt fysiologisk aktivt peptid og calcium-metabolisme-regulerende middel, der omfatter peptidet som effektiv besta
DK119391A (da) Humaninsulinanaloger
JPS53132539A (en) Protected amino acid or peptide having said protected amino acid residue
FR2425426A1 (fr) Peptides apparentes a la somatostatine
DK369888A (da) Peptidforbindelser