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NO903291L - Renin-hemmende aminooligohydroksyderivater. - Google Patents

Renin-hemmende aminooligohydroksyderivater.

Info

Publication number
NO903291L
NO903291L NO90903291A NO903291A NO903291L NO 903291 L NO903291 L NO 903291L NO 90903291 A NO90903291 A NO 90903291A NO 903291 A NO903291 A NO 903291A NO 903291 L NO903291 L NO 903291L
Authority
NO
Norway
Prior art keywords
aminooligo
hydroxyde
inhibitive
derivatives
pure
Prior art date
Application number
NO90903291A
Other languages
English (en)
Norwegian (no)
Other versions
NO903291D0 (no
Inventor
Heinz-Werner Kleemann
Hansjoerg Urbach
Adalbert Wagner
Dieter Ruppert
Wolfgang Linz
Werner Kramer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3924506A external-priority patent/DE3924506A1/de
Priority claimed from DE19893932817 external-priority patent/DE3932817A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO903291D0 publication Critical patent/NO903291D0/no
Publication of NO903291L publication Critical patent/NO903291L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
  • Solid Fuels And Fuel-Associated Substances (AREA)
NO90903291A 1989-07-25 1990-07-24 Renin-hemmende aminooligohydroksyderivater. NO903291L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3924506A DE3924506A1 (de) 1989-07-25 1989-07-25 Renin-hemmende aminooligohydroxy-derivate
DE19893932817 DE3932817A1 (de) 1989-09-30 1989-09-30 Renin-hemmende aminooligohydroxy-derivate

Publications (2)

Publication Number Publication Date
NO903291D0 NO903291D0 (no) 1990-07-24
NO903291L true NO903291L (no) 1991-01-28

Family

ID=25883333

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90903291A NO903291L (no) 1989-07-25 1990-07-24 Renin-hemmende aminooligohydroksyderivater.

Country Status (20)

Country Link
EP (1) EP0410278B1 (fi)
JP (1) JPH0366652A (fi)
KR (1) KR910002776A (fi)
CN (1) CN1049164A (fi)
AT (1) ATE100463T1 (fi)
AU (1) AU639246B2 (fi)
CA (1) CA2021822A1 (fi)
CS (1) CS368890A3 (fi)
DE (1) DE59004292D1 (fi)
DK (1) DK0410278T3 (fi)
ES (1) ES2062214T3 (fi)
FI (1) FI903701A7 (fi)
HU (1) HU205140B (fi)
IE (1) IE902686A1 (fi)
IL (1) IL95166A0 (fi)
MA (1) MA21913A1 (fi)
NO (1) NO903291L (fi)
NZ (1) NZ234608A (fi)
PL (1) PL286188A1 (fi)
PT (1) PT94798A (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW209870B (fi) * 1990-01-18 1993-07-21 Pfizer
IE68045B1 (en) * 1990-05-11 1996-05-15 Abbott Lab Renin inhibitors
EP0546115A1 (en) * 1990-08-24 1993-06-16 The Upjohn Company Peptides containing amino-polyols as transition-state mimics
EP0483403A1 (en) * 1990-10-31 1992-05-06 Hoechst Aktiengesellschaft Derivatives of amino acids as inhibitors of renin, methods for their preparation, medicaments containing them and their use
AU4686401A (en) * 2000-04-10 2001-10-23 Yuichi Ishida Hypotensors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK34086A (da) * 1985-01-23 1986-07-24 Abbott Lab Peptidylaminodioler
NZ218937A (en) * 1986-01-16 1990-03-27 Abbott Lab Functionalised peptidyl aminodiols and -triols as renin inhibitors and pharmaceutical compositions
US4863905A (en) * 1987-02-04 1989-09-05 Warner-Lambert Company Renin inhibitors II

Also Published As

Publication number Publication date
EP0410278A1 (de) 1991-01-30
CN1049164A (zh) 1991-02-13
HUT55033A (en) 1991-04-29
NO903291D0 (no) 1990-07-24
EP0410278B1 (de) 1994-01-19
PL286188A1 (en) 1991-04-22
IL95166A0 (en) 1991-06-10
HU205140B (en) 1992-03-30
HU904582D0 (en) 1990-12-28
NZ234608A (en) 1991-12-23
DE59004292D1 (de) 1994-03-03
FI903701A0 (fi) 1990-07-23
AU639246B2 (en) 1993-07-22
JPH0366652A (ja) 1991-03-22
ATE100463T1 (de) 1994-02-15
IE902686A1 (en) 1991-02-27
MA21913A1 (fr) 1991-04-01
AU5971990A (en) 1991-01-31
DK0410278T3 (da) 1994-05-24
KR910002776A (ko) 1991-02-26
CA2021822A1 (en) 1991-01-26
CS368890A3 (en) 1992-02-19
FI903701A7 (fi) 1991-01-26
PT94798A (pt) 1991-03-20
ES2062214T3 (es) 1994-12-16

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