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NO900155L - Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1. - Google Patents

Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1.

Info

Publication number
NO900155L
NO900155L NO90900155A NO900155A NO900155L NO 900155 L NO900155 L NO 900155L NO 90900155 A NO90900155 A NO 90900155A NO 900155 A NO900155 A NO 900155A NO 900155 L NO900155 L NO 900155L
Authority
NO
Norway
Prior art keywords
sicam
icam
purified
different
relates
Prior art date
Application number
NO90900155A
Other languages
English (en)
Other versions
NO900155D0 (no
Inventor
Jeffrey Greve
Alan Mcclelland
Original Assignee
Molecular Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26972210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO900155(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/301,192 external-priority patent/US5235049A/en
Application filed by Molecular Therapeutics Inc filed Critical Molecular Therapeutics Inc
Publication of NO900155D0 publication Critical patent/NO900155D0/no
Publication of NO900155L publication Critical patent/NO900155L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Bipolar Transistors (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

En oppløselig form av Intercellulært adhesjonsmolekyl (sICAW-1) og renset og isolert humant sICAW-1, er beskrevet. En renset og Isolert DNA-sekvens kodende for sICAM-l er også beskrevet. Den ekstracellulære domenen til sICAW-l og uoppløselig ICAM-1 er vesentlig Ilke. ICAW-1 er Involvert 1 prosessen hvor Isrmfocytter kobles til cellulære substrater 1 løpet av betennelse og virker som hovedhuæan-rhlnovlrusreseptor (HRR). sICAW-1 både reduserer Imraunbetennelse og temmer Infeksjon av rhlnovlrus og Coxsackle A-vlrus.
NO90900155A 1989-01-24 1990-01-11 Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1. NO900155L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/301,192 US5235049A (en) 1989-01-24 1989-01-24 Nucleic acid sequences encoding a soluble molecule (SICAM-1) related to but distinct from ICAM-1
US44595189A 1989-12-13 1989-12-13

Publications (2)

Publication Number Publication Date
NO900155D0 NO900155D0 (no) 1990-01-11
NO900155L true NO900155L (no) 1990-07-25

Family

ID=26972210

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90900155A NO900155L (no) 1989-01-24 1990-01-11 Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1.

Country Status (15)

Country Link
EP (1) EP0379904B1 (no)
JP (1) JP3080631B2 (no)
KR (1) KR100202435B1 (no)
AT (1) ATE137799T1 (no)
AU (1) AU641134B2 (no)
DE (1) DE69026844T2 (no)
DK (1) DK0379904T3 (no)
ES (1) ES2087091T3 (no)
FI (1) FI100601B (no)
GR (1) GR3020481T3 (no)
IE (1) IE74144B1 (no)
IL (1) IL93119A (no)
NO (1) NO900155L (no)
NZ (1) NZ232203A (no)
PT (1) PT92920B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
EP0362531B1 (en) * 1988-09-01 1999-11-10 Bayer Corporation A human rhinovirus receptor protein that inhibits virus infectivity
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
US5776775A (en) * 1989-02-21 1998-07-07 Dana-Farber Cancer Institute Anti-LAM 1-3 antibody and hybridoma
HU217792B (hu) * 1989-03-16 2000-04-28 Dana Farber Cancer Institute Eljárás intercelluláris adhéziós molekula (ICAM-1) oldható származékai és ezeket tartalmazó gyógyszerkészítmények előállítására
US6797270B1 (en) 1989-03-16 2004-09-28 Center For Blood Research, Inc. Functional derivatives of the intercellular adhesion molecule ICAM-1 in anti-viral therapy
ES2097748T3 (es) * 1989-03-16 1997-04-16 Blood Res Center Uso de derivados funcionales de la molecula de adhesion intercelular icam-1 en la terapia antivirica.
WO1991018011A1 (en) * 1990-05-15 1991-11-28 Swinburne Limited Inhibition of cell adhesion using intercellular adhesion molecule-1-like peptides and/or analogues thereof
WO1991018010A1 (en) * 1990-05-15 1991-11-28 Swinburne Limited Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof
EP0987329A3 (en) * 1990-07-20 2004-03-03 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US5871733A (en) * 1990-07-20 1999-02-16 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5674982A (en) * 1990-07-20 1997-10-07 Bayer Corporation Multimeric form of human rhinovirus receptor protein
AU710965B2 (en) * 1992-06-22 1999-09-30 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
AU687755B2 (en) * 1992-08-21 1998-03-05 Genentech Inc. Method for treating an LFA-1-mediated disorder
FR2710778B1 (fr) * 1993-09-29 1995-12-01 Framatome Sa Grappe de commande pour réacteur nucléaire et réacteur en faisant application.
DE4335273A1 (de) * 1993-10-15 1995-04-20 Univ Ludwigs Albert Peptide zur Tumortherapie
US5914112A (en) * 1996-01-23 1999-06-22 Genentech, Inc. Anti-CD18 antibodies in stroke
US20020081294A1 (en) 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
AU735917B2 (en) * 1997-10-02 2001-07-19 Icos Corporation ICAM-4 and diagnostic uses thereof
FR2788161B1 (fr) * 1998-12-30 2001-03-23 Framatome Sa Crayon absorbant pour grappe de commande de reacteur nucleaire
US6582698B1 (en) 1999-03-19 2003-06-24 Genentech, Inc. Treatment method
ES2331643T3 (es) 1999-03-19 2010-01-12 Genentech, Inc. Tratamiento de trastornos asociados con lfa-1 con dosis crecientes de antagonista de lfa-1.
CA2516013C (en) * 2003-02-14 2014-05-13 Beth Israel Deaconess Medical Center, Inc. Predicting graft rejection
JP4671323B2 (ja) * 2004-04-28 2011-04-13 大日本印刷株式会社 ディスプレイ装置
MXPA06014354A (es) 2004-06-09 2007-02-19 Genentech Inc Metodo para tratar granuloma anular o sarcoide.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3854536T2 (de) * 1987-05-04 1996-03-07 Dana Farber Cancer Inst Inc Interzellulare Adhäsions-Moleküle und deren Bindungsliganden.
ES2064327T3 (es) * 1987-11-02 1995-02-01 Baylor College Medicine Uso de icam-1 o de sus derivados funcionales para el tratamiento de una inflamacion no especifica.
CA1341055C (en) * 1987-12-08 2000-07-18 Alan Mcclelland Transfectant cell lines which express the major human rhinovirus receptor
EP0362531B1 (en) * 1988-09-01 1999-11-10 Bayer Corporation A human rhinovirus receptor protein that inhibits virus infectivity
AU636230B2 (en) * 1990-10-24 1993-04-22 Dolores Y. Beaupied Garment to hold an ostomy appliance

Also Published As

Publication number Publication date
IL93119A (en) 1999-07-14
ES2087091T3 (es) 1996-07-16
FI900331A0 (fi) 1990-01-22
DK0379904T3 (da) 1996-09-16
AU4876790A (en) 1990-08-02
IL93119A0 (en) 1990-11-05
IE900257L (en) 1990-07-24
JP3080631B2 (ja) 2000-08-28
KR900011895A (ko) 1990-08-02
DE69026844D1 (de) 1996-06-13
NZ232203A (en) 1992-10-28
NO900155D0 (no) 1990-01-11
PT92920B (pt) 1995-12-29
EP0379904A1 (en) 1990-08-01
GR3020481T3 (en) 1996-10-31
KR100202435B1 (ko) 1999-06-15
EP0379904B1 (en) 1996-05-08
FI100601B (fi) 1998-01-15
DE69026844T2 (de) 1996-09-12
ATE137799T1 (de) 1996-05-15
PT92920A (pt) 1990-07-31
IE74144B1 (en) 1997-07-02
AU641134B2 (en) 1993-09-16
JPH0381296A (ja) 1991-04-05

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