NO900070L - 2-aminopyrimidinonderivater. - Google Patents

2-aminopyrimidinonderivater.

Info

Publication number: NO900070L
Authority: NO; Norway
Prior art keywords: 6alkyl; hydrogen; furanyl; compounds; formula
Prior art date: 1989-01-09

Application number

NO90900070A

Other languages

English (en)

Other versions

NO172645C (no

NO172645B (no

NO900070D0 (no

Inventor

Frans Eduard Janssens

Ludo Edmond Josephine Kennis

Francois Maria Sommen

Ann Christina Joannes Dierckx

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-09

Filing date

1990-01-08

Publication date

1990-07-10

1990-01-08 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1990-01-08 Publication of NO900070D0 publication Critical patent/NO900070D0/no

1990-07-10 Publication of NO900070L publication Critical patent/NO900070L/no

1993-05-10 Publication of NO172645B publication Critical patent/NO172645B/no

1993-08-18 Publication of NO172645C publication Critical patent/NO172645C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO900070A 1989-01-09 1990-01-08 Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-aminopyrimidinonderivater NO172645C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898900380A GB8900380D0 (en)	1989-01-09	1989-01-09	2-aminopyrimidinone derivatives

Publications (4)

Publication Number	Publication Date
NO900070D0 NO900070D0 (no)	1990-01-08
NO900070L true NO900070L (no)	1990-07-10
NO172645B NO172645B (no)	1993-05-10
NO172645C NO172645C (no)	1993-08-18

Family

ID=10649777

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO900070A NO172645C (no)	1989-01-09	1990-01-08	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-aminopyrimidinonderivater

Country Status (20)

Country	Link
US (1)	US5008268A (no)
EP (1)	EP0378254B1 (no)
JP (1)	JPH02233678A (no)
CN (1)	CN1030452C (no)
AT (1)	ATE107642T1 (no)
AU (1)	AU622509B2 (no)
CA (1)	CA2007198A1 (no)
DE (1)	DE69010015T2 (no)
DK (1)	DK0378254T3 (no)
ES (1)	ES2058749T3 (no)
FI (1)	FI94526C (no)
GB (1)	GB8900380D0 (no)
HU (1)	HU206350B (no)
IE (1)	IE63153B1 (no)
IL (1)	IL92729A0 (no)
NO (1)	NO172645C (no)
NZ (1)	NZ231787A (no)
PH (1)	PH26908A (no)
RU (1)	RU1825364C (no)
ZA (1)	ZA90120B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE68908786T2 (de) *	1988-06-16	1994-03-17	Smith Kline French Lab	Condensierte Pyrimidinderivate, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.
GB8900382D0 (en) *	1989-01-09	1989-03-08	Janssen Pharmaceutica Nv	2-aminopyrimidinone derivatives
CA2043564A1 (en) *	1990-07-06	1992-01-07	Alfons G. M. De Knaep	3-[(5-methyl-2-furanyl)methyl]-n-(4-piperidinyl)-3h-imidazo [4,5-b]-pyridin-2-amine 2-hydroxy-1,2,3-propanetricarboxylate
NZ238863A (en) *	1990-07-19	1993-03-26	Janssen Pharmaceutica Nv	Substituted thiazolyl and pyridinyl derivatives
IL101851A (en) *	1991-06-13	1996-05-14	Janssen Pharmaceutica Nv	10-(4-piperidinyl- and piperidinylidene)-imidazo [1,2-a] (pyrrolo thieno or furano) [2,3] azepine derivatives their preparation and pharmaceutical compositions containing them and certain novel intermediates therefor
IL101850A (en) *	1991-06-13	1996-01-31	Janssen Pharmaceutica Nv	11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
AU3347493A (en) *	1992-01-09	1993-08-03	Janssen Pharmaceutica N.V.	Pharmaceutically active substituted benzimidazole derivatives
GR1001393B (el) *	1992-10-12	1993-10-29	Janssen Pharmaceutica Nv	Παράγωγα ιμιδαζο[2,1-Β] 3] βενζαζεπίνης, συν?έσεις και μέ?οδος χρήσεως.
GR1001385B (el) *	1992-10-12	1993-10-29	Janssen Pharmaceutica Nv	Παράγωγα ιμιδαζο 1,2-α (πυρρολο,?ειενο η φουρανο) 3,2-d αζεπίνης συν?έσεις και μέ?οδοι χρήσεως.
US5521183A (en) *	1994-08-30	1996-05-28	Allergan	Use of 5-HT ligands as anti-pruritic agents
US6211199B1 (en)	1995-11-17	2001-04-03	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6423704B2 (en)	1995-12-20	2002-07-23	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6194406B1 (en)	1995-12-20	2001-02-27	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US5932571A (en) *	1996-02-21	1999-08-03	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en)	1996-02-21	1999-12-07	Hoescht Marion Roussel, Inc.	Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5922737A (en) *	1996-02-21	1999-07-13	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
ES2594655T3 (es)	2006-03-31	2016-12-21	Vistakon Pharmaceuticals, Llc	Tratamiento de alergias oculares
CN101671336B (zh)	2009-09-23	2013-11-13	辽宁利锋科技开发有限公司	芳杂环并嘧啶衍生物和类似物及其制备方法和用途
CN112574219A (zh) *	2021-01-31	2021-03-30	湖北大学	一种苯并咪唑并嘧啶酮衍生物的合成方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4219559A (en) *	1979-01-10	1980-08-26	Janssen Pharmaceutica N.V.	N-Heterocyclyl-4-piperidinamines
US4556660A (en) *	1982-07-12	1985-12-03	Janssen Pharmaceutica N.V.	N-(Bicyclic heterocyclyl)-4-piperidinamines
US4634704A (en) *	1983-10-06	1987-01-06	Janssen Pharmaceutica, N.V.	Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
DE3484096D1 (de) *	1983-11-30	1991-03-14	Janssen Pharmaceutica Nv	Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine.
US4695569A (en) *	1983-11-30	1987-09-22	Janssen Pharmaceutica N.V.	Bicyclic heterocyclyl containing N-(bicyclic heterocyclyl)-4-piperidinamines
PH23995A (en) *	1984-01-09	1990-02-09	Janssen Pharmaceutica Nv	4((bicycle heterocyclyl)-methyl and hetero)piperidines
US4588722A (en) *	1984-01-09	1986-05-13	Janssen Pharmaceutica N.V.	N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
US4695575A (en) *	1984-11-13	1987-09-22	Janssen Pharmaceutica, N.V.	4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
GB8515934D0 (en) *	1985-06-24	1985-07-24	Janssen Pharmaceutica Nv	(4-piperidinomethyl and-hetero)purines
US4835161A (en) *	1986-02-03	1989-05-30	Janssen Pharmaceutica N.V.	Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines
NZ223654A (en) *	1987-03-09	1990-03-27	Janssen Pharmaceutica Nv	1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions
US4897401A (en) *	1987-06-19	1990-01-30	Janssen Pharmaceutical N.V.	N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases
EP0297742A3 (en) *	1987-06-22	1990-05-16	Elopak Systems Ag	Flat top end closure for liquid containers
CA1317939C (en) *	1987-07-01	1993-05-18	Janssen Pharmaceutica Naamloze Vennootschap	¬(bicyclic heterocyclyl)methyl and -hetero\| substituted hexahydro-1h-azepines and pyrrolidines
GB8716313D0 (en) *	1987-07-10	1987-08-19	Janssen Pharmaceutica Nv	2-(heterocyclylalkyl)imidazopyridines

1989
- 1989-01-09 GB GB898900380A patent/GB8900380D0/en active Pending
- 1989-12-14 NZ NZ231787A patent/NZ231787A/en unknown
- 1989-12-15 IL IL92729A patent/IL92729A0/xx not_active IP Right Cessation
- 1989-12-26 US US07/456,391 patent/US5008268A/en not_active Expired - Fee Related
1990
- 1990-01-03 DE DE69010015T patent/DE69010015T2/de not_active Expired - Fee Related
- 1990-01-03 DK DK90200004.1T patent/DK0378254T3/da active
- 1990-01-03 ES ES90200004T patent/ES2058749T3/es not_active Expired - Lifetime
- 1990-01-03 EP EP90200004A patent/EP0378254B1/en not_active Expired - Lifetime
- 1990-01-03 AT AT90200004T patent/ATE107642T1/de not_active IP Right Cessation
- 1990-01-05 CA CA002007198A patent/CA2007198A1/en not_active Abandoned
- 1990-01-08 PH PH39860A patent/PH26908A/en unknown
- 1990-01-08 HU HU9063A patent/HU206350B/hu not_active IP Right Cessation
- 1990-01-08 AU AU47780/90A patent/AU622509B2/en not_active Ceased
- 1990-01-08 NO NO900070A patent/NO172645C/no unknown
- 1990-01-08 IE IE6890A patent/IE63153B1/en not_active IP Right Cessation
- 1990-01-08 ZA ZA90120A patent/ZA90120B/xx unknown
- 1990-01-08 FI FI900084A patent/FI94526C/fi not_active IP Right Cessation
- 1990-01-08 RU SU904742861A patent/RU1825364C/ru active
- 1990-01-09 CN CN90100077A patent/CN1030452C/zh not_active Expired - Fee Related
- 1990-01-09 JP JP2002414A patent/JPH02233678A/ja active Pending

Also Published As

Publication number	Publication date
AU622509B2 (en)	1992-04-09
EP0378254B1 (en)	1994-06-22
ATE107642T1 (de)	1994-07-15
NO172645C (no)	1993-08-18
AU4778090A (en)	1990-07-12
FI900084A0 (fi)	1990-01-08
HU206350B (en)	1992-10-28
US5008268A (en)	1991-04-16
CA2007198A1 (en)	1990-07-09
RU1825364C (ru)	1993-06-30
DE69010015D1 (de)	1994-07-28
HUT53364A (en)	1990-10-28
ZA90120B (en)	1991-09-25
DK0378254T3 (da)	1994-07-25
IE63153B1 (en)	1995-03-22
EP0378254A3 (en)	1991-01-09
DE69010015T2 (de)	1994-11-24
FI900084A7 (fi)	1990-07-10
JPH02233678A (ja)	1990-09-17
EP0378254A2 (en)	1990-07-18
HU900063D0 (en)	1990-03-28
FI94526B (fi)	1995-06-15
ES2058749T3 (es)	1994-11-01
NO172645B (no)	1993-05-10
CN1044099A (zh)	1990-07-25
PH26908A (en)	1992-12-03
IL92729A0 (en)	1990-09-17
GB8900380D0 (en)	1989-03-08
CN1030452C (zh)	1995-12-06
NO900070D0 (no)	1990-01-08
FI94526C (fi)	1995-09-25
NZ231787A (en)	1991-07-26
IE900068L (en)	1990-07-09

Publication	Publication Date	Title
ATE107642T1 (de)	1994-07-15	2-aminopyrimidinon-derivate.
DE69008366D1 (de)	1994-06-01	2-Aminopyrimidinon-Derivate.
GR3005715T3 (no)	1993-06-07
ATE79878T1 (de)	1992-09-15	N-(4-piperidinyl)-bizyklisch kondensierte 2imidazolamin-derivate.
ATE114653T1 (de)	1994-12-15	Hydroxyalkylfuranyl-derivate.