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NO905067D0 - Nye isoindolonderivater og deres fremstilling. - Google Patents

Nye isoindolonderivater og deres fremstilling.

Info

Publication number
NO905067D0
NO905067D0 NO905067A NO905067A NO905067D0 NO 905067 D0 NO905067 D0 NO 905067D0 NO 905067 A NO905067 A NO 905067A NO 905067 A NO905067 A NO 905067A NO 905067 D0 NO905067 D0 NO 905067D0
Authority
NO
Norway
Prior art keywords
derivatives
preparation
new
isoindolond
radicals
Prior art date
Application number
NO905067A
Other languages
English (en)
Other versions
NO174148B (no
NO905067L (no
NO174148C (no
Inventor
Marie-Christine Dubroeucq
Claude Moutonnier
Jean-Francois Peyronel
Michel Tabart
Alain Truchon
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of NO905067D0 publication Critical patent/NO905067D0/no
Publication of NO905067L publication Critical patent/NO905067L/no
Publication of NO174148B publication Critical patent/NO174148B/no
Publication of NO174148C publication Critical patent/NO174148C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO905067A 1989-11-23 1990-11-22 Nye isoindolonderivater NO174148C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8915407A FR2654726B1 (fr) 1989-11-23 1989-11-23 Nouveaux derives de l'isoindolone et leur preparation.

Publications (4)

Publication Number Publication Date
NO905067D0 true NO905067D0 (no) 1990-11-22
NO905067L NO905067L (no) 1991-05-24
NO174148B NO174148B (no) 1993-12-13
NO174148C NO174148C (no) 1994-03-23

Family

ID=9387708

Family Applications (1)

Application Number Title Priority Date Filing Date
NO905067A NO174148C (no) 1989-11-23 1990-11-22 Nye isoindolonderivater

Country Status (23)

Country Link
US (1) US5112988A (no)
EP (1) EP0430771B1 (no)
JP (1) JPH03176468A (no)
KR (1) KR910009660A (no)
AT (1) ATE108774T1 (no)
AU (1) AU635984B2 (no)
CA (1) CA2030570A1 (no)
DE (1) DE69010851T2 (no)
DK (1) DK0430771T3 (no)
ES (1) ES2057488T3 (no)
FI (1) FI94627C (no)
FR (1) FR2654726B1 (no)
HU (1) HU214574B (no)
IE (1) IE64737B1 (no)
IL (1) IL96447A (no)
NO (1) NO174148C (no)
NZ (1) NZ236175A (no)
PL (2) PL164955B1 (no)
PT (1) PT95983B (no)
RU (1) RU2104269C1 (no)
SK (1) SK278474B6 (no)
YU (1) YU47437B (no)
ZA (1) ZA909370B (no)

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FR2676442B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2688219B1 (fr) 1992-03-03 1994-07-08 Sanofi Elf Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
FR2689889B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, et leur preparation.
US5830854A (en) * 1992-12-14 1998-11-03 Merck Sharp & Dohme, Limited Method of treating cystic fibrosis using a tachykinin receptor antagonist
FR2703679B1 (fr) * 1993-04-05 1995-06-23 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
TW365603B (en) * 1993-07-30 1999-08-01 Rhone Poulenc Rorer Sa Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
FR2710913B1 (fr) * 1993-10-07 1995-11-24 Rhone Poulenc Rorer Sa Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2709752B1 (fr) * 1993-07-30 1995-10-06 Rhone Poulenc Rorer Sa Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5543530A (en) * 1993-12-23 1996-08-06 Ortho Pharmaceutical Corporation 4-arylisoindole analgesics
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2729954B1 (fr) 1995-01-30 1997-08-01 Sanofi Sa Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
FR2755013B1 (fr) * 1996-10-29 1998-11-27 Rhone Poulenc Rorer Sa Nouvelle application therapeutique des antagonistes de la substance p
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AU2008269154B2 (en) 2007-06-27 2014-06-12 Merck Sharp & Dohme Llc 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
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US8691825B2 (en) 2009-04-01 2014-04-08 Merck Sharp & Dohme Corp. Inhibitors of AKT activity
KR20120023072A (ko) 2009-05-12 2012-03-12 브리스톨-마이어스 스큅 컴퍼니 (S)-7-(〔1,2,4〕트리아졸〔1,5-a〕피리딘-6-일)-4-(3,4-디클로로페닐)-1,2,3,4-테트라하이드로이소퀴놀린의 결정형 및 이의 용도
EA020553B1 (ru) 2009-05-12 2014-12-30 Олбани Молекьюлар Рисерч, Инк. 7-([1,2,4]ТРИАЗОЛО[1,5-α]ПИРИДИН-6-ИЛ)-4-(3,4-ДИХЛОРФЕНИЛ)-1,2,3,4-ТЕТРАГИДРОИЗОХИНОЛИН, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕГО ОСНОВЕ И СПОСОБЫ ЛЕЧЕНИЯ НЕВРОЛОГИЧЕСКИХ И ПСИХИЧЕСКИХ РАССТРОЙСТВ
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CN102638981B (zh) 2009-10-14 2015-07-22 默沙东公司 提高p53活性的取代的哌啶和其用途
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US20160194368A1 (en) 2013-09-03 2016-07-07 Moderna Therapeutics, Inc. Circular polynucleotides
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US2858314A (en) * 1954-06-07 1958-10-28 Georgian Vlasios Hydrocarbazolenines
US4042707A (en) * 1976-02-19 1977-08-16 E. I. Du Pont De Nemours And Company 3α-Arylhydroisoindoles
IT1113879B (it) * 1979-03-15 1986-01-27 Farmatis Spa Derivato isoindolinico,processo per la sua preparazione e composizioni terapeutiche che lo comprendono come principio attivo
US4494547A (en) * 1981-03-30 1985-01-22 North Carolina Central University 2H-isoindolediones, their synthesis and use as radiosensitizers
DE3133302A1 (de) * 1981-08-22 1983-03-03 Beiersdorf Ag, 2000 Hamburg Isoindolin-2-yl-amino-imidazoline und isoindolin-2-yl-guanidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP0091241B1 (en) * 1982-04-02 1988-12-28 Takeda Chemical Industries, Ltd. Condensed pyrrolinone derivatives, and their production
ATE87307T1 (de) * 1985-12-09 1993-04-15 Banyu Pharma Co Ltd Isoindolinderivate und verfahren zu ihrer herstellung.

Also Published As

Publication number Publication date
JPH03176468A (ja) 1991-07-31
PT95983B (pt) 1998-01-30
NO174148B (no) 1993-12-13
CA2030570A1 (fr) 1991-05-24
YU223590A (sh) 1993-05-28
DE69010851D1 (de) 1994-08-25
HUT55756A (en) 1991-06-28
KR910009660A (ko) 1991-06-28
DK0430771T3 (da) 1994-08-29
FR2654726A1 (fr) 1991-05-24
NZ236175A (en) 1993-03-26
FI905770L (fi) 1991-05-24
NO905067L (no) 1991-05-24
EP0430771A1 (fr) 1991-06-05
FR2654726B1 (fr) 1992-02-14
FI94627B (fi) 1995-06-30
ES2057488T3 (es) 1994-10-16
RU2104269C1 (ru) 1998-02-10
PL164973B1 (pl) 1994-10-31
PT95983A (pt) 1991-09-13
IL96447A (en) 1995-03-15
IE904234A1 (en) 1991-06-05
SK580690A3 (en) 1997-07-09
ATE108774T1 (de) 1994-08-15
IE64737B1 (en) 1995-09-06
DE69010851T2 (de) 1994-11-24
PL164955B1 (en) 1994-10-31
US5112988A (en) 1992-05-12
AU635984B2 (en) 1993-04-08
FI905770A0 (fi) 1990-11-22
IL96447A0 (en) 1991-08-16
SK278474B6 (en) 1997-07-09
HU214574B (hu) 1998-04-28
NO174148C (no) 1994-03-23
ZA909370B (en) 1991-10-30
HU907249D0 (en) 1991-05-28
AU6682890A (en) 1991-05-30
YU47437B (sh) 1995-03-27
PL287908A1 (en) 1991-12-02
EP0430771B1 (fr) 1994-07-20
FI94627C (fi) 1995-10-10

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