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NO890174L - RECOMBINANT INTERLEUKIN-1ALFA POLYPEPTIDES. - Google Patents

RECOMBINANT INTERLEUKIN-1ALFA POLYPEPTIDES.

Info

Publication number
NO890174L
NO890174L NO89890174A NO890174A NO890174L NO 890174 L NO890174 L NO 890174L NO 89890174 A NO89890174 A NO 89890174A NO 890174 A NO890174 A NO 890174A NO 890174 L NO890174 L NO 890174L
Authority
NO
Norway
Prior art keywords
polypeptides
1alfa
dna sequences
recombinant interleukin
recombinant vectors
Prior art date
Application number
NO89890174A
Other languages
Norwegian (no)
Other versions
NO890174D0 (en
Inventor
Peter T Lomedico
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO890174D0 publication Critical patent/NO890174D0/en
Publication of NO890174L publication Critical patent/NO890174L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/545IL-1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Homogene rekombinante huaane intarleukin-lo polypep- tider, DNA-sekvenser som koder for slike polypeptider, rekonbinante vektorer inneholdende DNA-sekvenser, én- cellede vertsorganismer inneholdende slike rekonbinante vektorer, samt fremgangsmåter for fremstilling av polypeptidene. De humane interleukin-loc polypeptider og farmasøytiske blandinger inneholdende disse kan bli brukt for a stimulere immunsystemet hos en vert for å fremme sårleging og for a forbedre legingen av kritisk syke protein-undererruerte pasienter.Homogeneous recombinant human intarleukinol polypeptides, DNA sequences encoding such polypeptides, recombinant vectors containing DNA sequences, single-cell host organisms containing such recombinant vectors, and methods for producing the polypeptides. The human interleukin-loc polypeptides and pharmaceutical compositions containing them may be used to stimulate a host's immune system to promote wound healing and to improve the healing of critically ill protein-disrupted patients.

NO89890174A 1988-01-15 1989-01-13 RECOMBINANT INTERLEUKIN-1ALFA POLYPEPTIDES. NO890174L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14445788A 1988-01-15 1988-01-15

Publications (2)

Publication Number Publication Date
NO890174D0 NO890174D0 (en) 1989-01-13
NO890174L true NO890174L (en) 1989-07-17

Family

ID=22508674

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89890174A NO890174L (en) 1988-01-15 1989-01-13 RECOMBINANT INTERLEUKIN-1ALFA POLYPEPTIDES.

Country Status (19)

Country Link
EP (1) EP0324447B1 (en)
JP (1) JP2567079B2 (en)
AR (1) AR245958A1 (en)
AT (1) ATE142696T1 (en)
AU (1) AU616461B2 (en)
DE (1) DE58909723D1 (en)
DK (1) DK16489A (en)
ES (1) ES2091752T3 (en)
FI (1) FI890175A7 (en)
GR (1) GR3021887T3 (en)
HU (1) HU208996B (en)
IE (1) IE890087L (en)
IL (1) IL88934A (en)
MC (1) MC2002A1 (en)
NO (1) NO890174L (en)
NZ (1) NZ227594A (en)
PT (1) PT89438B (en)
YU (1) YU6889A (en)
ZA (1) ZA89202B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3587605T2 (en) * 1984-12-25 1994-03-17 Dainippon Pharmaceutical Co Interleukin-1 and its derivative.
DE3818660A1 (en) * 1987-06-05 1988-12-15 Colgate Palmolive Co FREE-FLOWING, POWDERY DISHWASHING DETERGENT AND METHOD FOR PRODUCING THE SAME
KR960008010B1 (en) * 1988-07-29 1996-06-19 오오쓰까세이야꾸 가부시끼가이샤 IL-1Ñß DERIVATIVES AND MEDICAMENT FOR TREATING THROMBOCYTOPENIA
US7176179B1 (en) 1997-05-30 2007-02-13 The Regents Of The University Of California Selective induction of cell death by delivery of amino-terminal interleukin-1-α pro-piece polypeptide
US6191269B1 (en) 1997-05-30 2001-02-20 The Regents Of The University Of California Selective induction of cell death by delivery of amino-terminal interleukin-1-α pro-piece polypeptide
US20030154504A1 (en) 1998-06-24 2003-08-14 Farese Robert V. Methods and compositions for modulating carbohydrate metabolism
DE10252634A1 (en) * 2002-11-11 2004-05-27 Umwelttechnik Georg Fritzmeier Gmbh & Co. Purification of sewage or other substances laden with harmful organic matter and detergent or clarifying agent also useful laundry and cleaning surfaces involve introduction of photosensitizer releasing singlet oxygen when stimulated
EP2464330B1 (en) * 2009-09-29 2016-03-23 United Technologies UT AG Oral care compositions containing human recombinant interleukin-1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3587605T2 (en) * 1984-12-25 1994-03-17 Dainippon Pharmaceutical Co Interleukin-1 and its derivative.
EP0200986B2 (en) * 1985-04-25 1998-03-11 F. Hoffmann-La Roche Ag Recombinant human interleukin-1
DE3515217A1 (en) * 1985-04-26 1986-10-30 Siemens AG, 1000 Berlin und 8000 München DEVICE FOR MEASURING LOW MAGNETIC FIELDS
US5017692A (en) * 1986-09-04 1991-05-21 Schering Corporation Truncated human interleukin-a alpha

Also Published As

Publication number Publication date
FI890175L (en) 1989-07-16
NZ227594A (en) 1991-09-25
EP0324447A2 (en) 1989-07-19
DK16489A (en) 1989-07-16
AU616461B2 (en) 1991-10-31
IL88934A (en) 1994-05-30
HUT50505A (en) 1990-02-28
EP0324447B1 (en) 1996-09-11
JP2567079B2 (en) 1996-12-25
AR245958A1 (en) 1994-03-30
ATE142696T1 (en) 1996-09-15
AU2850989A (en) 1989-07-20
FI890175A7 (en) 1989-07-16
YU6889A (en) 1990-08-31
EP0324447A3 (en) 1990-01-31
NO890174D0 (en) 1989-01-13
IE890087L (en) 1989-07-15
DK16489D0 (en) 1989-01-13
ZA89202B (en) 1989-09-27
FI890175A0 (en) 1989-01-13
GR3021887T3 (en) 1997-03-31
DE58909723D1 (en) 1996-10-17
MC2002A1 (en) 1990-01-26
JPH025892A (en) 1990-01-10
ES2091752T3 (en) 1996-11-16
PT89438A (en) 1990-02-08
IL88934A0 (en) 1989-08-15
HU208996B (en) 1994-09-28
PT89438B (en) 1993-09-30

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