NO895165D0 - Pyrazolopyridin-type mevalono-laktoner. - Google Patents
Pyrazolopyridin-type mevalono-laktoner.Info
- Publication number
- NO895165D0 NO895165D0 NO1989895165A NO895165A NO895165D0 NO 895165 D0 NO895165 D0 NO 895165D0 NO 1989895165 A NO1989895165 A NO 1989895165A NO 895165 A NO895165 A NO 895165A NO 895165 D0 NO895165 D0 NO 895165D0
- Authority
- NO
- Norway
- Prior art keywords
- laktoner
- mevalono
- pyrazolopyridine
- type
- pyrazolopyridine type
- Prior art date
Links
- AMFYRKOUWBAGHV-UHFFFAOYSA-N 1h-pyrazolo[4,3-b]pyridine Chemical compound C1=CN=C2C=NNC2=C1 AMFYRKOUWBAGHV-UHFFFAOYSA-N 0.000 title 1
- 230000000879 anti-atherosclerotic effect Effects 0.000 abstract 1
- 230000001315 anti-hyperlipaemic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10309088 | 1988-04-26 | ||
| JP27143988 | 1988-10-27 | ||
| JP1684689 | 1989-01-26 | ||
| PCT/JP1989/000423 WO1989010365A1 (en) | 1988-04-26 | 1989-04-19 | Pyrazolopyridine type mevalonolactones |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO895165D0 true NO895165D0 (no) | 1989-12-21 |
| NO895165L NO895165L (no) | 1989-12-21 |
| NO173501B NO173501B (no) | 1993-09-13 |
| NO173501C NO173501C (no) | 1993-12-22 |
Family
ID=27281590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO895165A NO173501C (no) | 1988-04-26 | 1989-12-21 | Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyrazolo-pyridinforbindelser |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0339358B1 (no) |
| JP (1) | JP2890448B2 (no) |
| KR (1) | KR970009222B1 (no) |
| AT (1) | ATE108450T1 (no) |
| DE (1) | DE68916685T2 (no) |
| DK (1) | DK659089D0 (no) |
| FI (1) | FI90870C (no) |
| HU (1) | HU203888B (no) |
| NO (1) | NO173501C (no) |
| WO (1) | WO1989010365A1 (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3130342B2 (ja) * | 1991-10-04 | 2001-01-31 | 日産化学工業株式会社 | 動脈硬化性血管内膜肥厚抑制薬 |
| EP1270572A4 (en) * | 2000-03-27 | 2005-03-23 | Takeda Pharmaceutical | CONDENSED PYRAZOLE DERIVATIVES, PROCESS FOR PRODUCTION AND USE |
| WO2009000832A2 (en) * | 2007-06-25 | 2008-12-31 | Boehringer Ingelheim International Gmbh | Chemical compounds |
| EP2215089B1 (en) | 2007-11-02 | 2012-06-27 | Vertex Pharmaceuticals Incorporated | [1h- pyrazolo [3, 4-b]pyridine-4-yl]-phenyle or -pyridin-2-yle derivatives as protein kinase c-theta |
| CN105732639A (zh) | 2012-06-29 | 2016-07-06 | 辉瑞大药厂 | 作为LRRK2抑制剂的4-(取代的氨基)-7H-吡咯并〔2,3-d〕嘧啶类 |
| US9695171B2 (en) | 2013-12-17 | 2017-07-04 | Pfizer Inc. | 3,4-disubstituted-1 H-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7H-pyrrolo[2,3-c]pyridazines as LRRK2 inhibitors |
| AU2016322813B2 (en) | 2015-09-14 | 2021-04-01 | Pfizer Inc. | Novel imidazo (4,5-c) quinoline and imidazo (4,5-c)(1,5) naphthyridine derivatives as LRRK2 inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU570021B2 (en) * | 1982-11-22 | 1988-03-03 | Novartis Ag | Analogs of mevalolactone |
| DE3582674D1 (de) * | 1984-06-22 | 1991-05-29 | Sandoz Ag | Pyrazolanaloge von mevalonolakton und abkoemmlinge davon, verfahren zu deren herstellung und deren verwendung. |
| US4761419A (en) * | 1987-12-07 | 1988-08-02 | Warner-Lambert Company | 6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
| US4822799A (en) * | 1988-01-27 | 1989-04-18 | Sandoz Pharm. Corp. | Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals |
-
1989
- 1989-04-07 JP JP1088534A patent/JP2890448B2/ja not_active Expired - Fee Related
- 1989-04-11 DE DE68916685T patent/DE68916685T2/de not_active Expired - Fee Related
- 1989-04-11 AT AT89106401T patent/ATE108450T1/de not_active IP Right Cessation
- 1989-04-11 EP EP89106401A patent/EP0339358B1/en not_active Expired - Lifetime
- 1989-04-19 WO PCT/JP1989/000423 patent/WO1989010365A1/en not_active Ceased
- 1989-04-19 KR KR1019890702338A patent/KR970009222B1/ko not_active Expired - Lifetime
- 1989-04-19 HU HU892751A patent/HU203888B/hu not_active IP Right Cessation
- 1989-12-21 NO NO895165A patent/NO173501C/no unknown
- 1989-12-22 DK DK659089A patent/DK659089D0/da not_active Application Discontinuation
- 1989-12-22 FI FI896251A patent/FI90870C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0339358A1 (en) | 1989-11-02 |
| DK659089A (da) | 1989-12-22 |
| NO173501C (no) | 1993-12-22 |
| DE68916685T2 (de) | 1995-02-09 |
| KR900700480A (ko) | 1990-08-13 |
| KR970009222B1 (ko) | 1997-06-09 |
| FI90870C (fi) | 1994-04-11 |
| WO1989010365A1 (en) | 1989-11-02 |
| NO895165L (no) | 1989-12-21 |
| FI90870B (fi) | 1993-12-31 |
| EP0339358B1 (en) | 1994-07-13 |
| FI896251A0 (fi) | 1989-12-22 |
| DK659089D0 (da) | 1989-12-22 |
| HU203888B (en) | 1991-10-28 |
| ATE108450T1 (de) | 1994-07-15 |
| NO173501B (no) | 1993-09-13 |
| JP2890448B2 (ja) | 1999-05-17 |
| DE68916685D1 (de) | 1994-08-18 |
| JPH02275878A (ja) | 1990-11-09 |
| HU892751D0 (en) | 1990-03-28 |
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