NO870323D0 - Fremgangsmaate for fremstilling av et rekombinant kompleks med humanfaktor viii:c aktivitet. - Google Patents

Fremgangsmaate for fremstilling av et rekombinant kompleks med humanfaktor viii:c aktivitet.

Info

Publication number: NO870323D0
Authority: NO; Norway
Prior art keywords: factor viii; activity; preparing; procedure; human factor
Prior art date: 1986-01-27

Application number

NO870323A

Other languages

English (en)

Other versions

NO179106B (no

NO870323L (no

NO179106C (no

Inventor

Rae Lyn Burke

Mirella Ezban Rasmussen

Original Assignee

Chiron Corp

Nordisk Gentofte

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-27

Filing date

1987-01-27

Publication date

1987-01-27

1987-01-27 Application filed by Chiron Corp, Nordisk Gentofte filed Critical Chiron Corp

1987-01-27 Publication of NO870323D0 publication Critical patent/NO870323D0/no

1987-07-28 Publication of NO870323L publication Critical patent/NO870323L/no

1996-04-29 Publication of NO179106B publication Critical patent/NO179106B/no

1996-08-07 Publication of NO179106C publication Critical patent/NO179106C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biochemistry (AREA)
Wood Science & Technology (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Plant Pathology (AREA)
Medicinal Chemistry (AREA)
Hematology (AREA)
Gastroenterology & Hepatology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)

NO870323A 1986-01-27 1987-01-27 Fremgangsmåte for fremstilling av og ekspresjonssystem som koder for og kan uttrykke et rekombinant proteinkompleks med humanfaktor V111:C-aktivitet NO179106C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US82298986A	1986-01-27	1986-01-27

Publications (4)

Publication Number	Publication Date
NO870323D0 true NO870323D0 (no)	1987-01-27
NO870323L NO870323L (no)	1987-07-28
NO179106B NO179106B (no)	1996-04-29
NO179106C NO179106C (no)	1996-08-07

Family

ID=25237495

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO870323A NO179106C (no)	1986-01-27	1987-01-27	Fremgangsmåte for fremstilling av og ekspresjonssystem som koder for og kan uttrykke et rekombinant proteinkompleks med humanfaktor V111:C-aktivitet

Country Status (9)

Country	Link
EP (1)	EP0232112B1 (no)
JP (3)	JPH0797996B2 (no)
AT (1)	ATE97956T1 (no)
AU (1)	AU610059B2 (no)
DE (1)	DE3788289T2 (no)
DK (1)	DK175407B1 (no)
ES (1)	ES2059361T3 (no)
FI (1)	FI98829C (no)
NO (1)	NO179106C (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7138505B1 (en)	1984-01-12	2006-11-21	Novartis Vaccines And Diagnostics, Inc.	Factor VIII:C nucleic acid molecules
KR910006424B1 (ko) *	1985-08-21	1991-08-24	인코텍스 비.브이	편성브리프(brief) 제조방법
US5198349A (en) *	1986-01-03	1993-03-30	Genetics Institute, Inc.	Method for producing factor VIII:C and analogs
US5595886A (en)	1986-01-27	1997-01-21	Chiron Corporation	Protein complexes having Factor VIII:C activity and production thereof
US5422260A (en) *	1986-05-29	1995-06-06	Genetics Institute, Inc. -Legal Affairs	Human factor VIII:c muteins
EP0251843A1 (fr) *	1986-06-06	1988-01-07	Transgene S.A.	Procédé de préparation de facteur VIII à partir de cellules de mammifères
FR2613379B2 (fr) *	1987-04-03	1990-04-06	Transgene Sa	Procede de preparation de fragments du facteur viii a partir de cellules de mammiferes
IL83192A (en) *	1986-07-18	1992-11-15	Gist Brocades Nv	Method for the preparation of proteins with factor viii activity by microbial host cells;expression vectors,host cells,antibodies
US6060447A (en) *	1987-05-19	2000-05-09	Chiron Corporation	Protein complexes having Factor VIII:C activity and production thereof
IE69026B1 (en)	1987-06-12	1996-08-07	Immuno Ag	Novel proteins with factor VIII activity process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
AU627150B2 (en) *	1987-06-12	1992-08-20	Immuno Ag	Novel proteins with factor viii activity: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
US6346513B1 (en)	1987-06-12	2002-02-12	Baxter Trading Gmbh	Proteins with factor VIII activity: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
EP0690126B1 (en) *	1987-06-12	2001-11-28	Baxter Aktiengesellschaft	Novel proteins with factor VIII activitiy: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
JPH0387173A (ja) *	1987-09-10	1991-04-11	Teijin Ltd	ヒト活性化天然型ファクター８ｃの製造方法及びそれに用いる形質転換体
WO1991007490A1 (en) *	1989-11-17	1991-05-30	Novo Nordisk A/S	Protein complexes having factor viii:c activity and production thereof
FR2657884B1 (fr)	1990-02-05	1994-09-02	Tm Innovation	Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
US5610033A (en) *	1990-04-25	1997-03-11	Novo Nordisk A/S	Method of producing proteins with FVIII activity and/or FVIII derivatives
CA2078721A1 (en) *	1991-09-24	1993-03-25	Hiroshi Yonemura	Process for preparing human coagulation factor viii protein complex
DK53792D0 (da) *	1992-04-24	1992-04-24	Novo Nordisk As	Fremgangsmaade til fremstilling af proteiner
US6221349B1 (en)	1998-10-20	2001-04-24	Avigen, Inc.	Adeno-associated vectors for expression of factor VIII by target cells
US6200560B1 (en)	1998-10-20	2001-03-13	Avigen, Inc.	Adeno-associated virus vectors for expression of factor VIII by target cells
NZ545628A (en)	2003-09-30	2009-04-30	Univ Pennsylvania	Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor
EP1707634A1 (en)	2005-03-29	2006-10-04	Octapharma AG	Method for isolation of recombinantly produced proteins
EP2359866B1 (en)	2005-04-07	2013-07-17	The Trustees of The University of Pennsylvania	Modified AAV rh48 capsids, compositions containing same and uses thereof
EP1739179A1 (en)	2005-06-30	2007-01-03	Octapharma AG	Serum-free stable transfection and production of recombinant human proteins in human cell lines
WO2011095604A1 (en)	2010-02-04	2011-08-11	Octapharma Biopharmaceuticals Gmbh	Half-life prolongation of proteins
US9315825B2 (en)	2010-03-29	2016-04-19	The Trustees Of The University Of Pennsylvania	Pharmacologically induced transgene ablation system
SG10201502270TA (en)	2010-03-29	2015-05-28	Univ Pennsylvania	Pharmacologically induced transgene ablation system
SG10201601110VA (en)	2011-02-17	2016-03-30	Univ Pennsylvania	Compositions and methods for altering tissue specificity and improving aav9-mediated gene transfer
US9719106B2 (en)	2013-04-29	2017-08-01	The Trustees Of The University Of Pennsylvania	Tissue preferential codon modified expression cassettes, vectors containing same, and uses thereof
CN108093639B (zh)	2015-04-16	2022-07-19	埃默里大学	用于肝脏中蛋白质表达的重组启动子和载体及其用途
JP6577401B2 (ja)	2016-03-31	2019-09-18	本田技研工業株式会社	ダクトへのレゾネータの取付け構造
CA3188420A1 (en)	2020-08-07	2022-02-10	Joseph Bauman	Vesicle targeting proteins and uses of same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2534273B1 (fr) *	1982-10-07	1985-09-13	Pasteur Institut	Lignees cellulaires originaires de mammiferes superieurs, productrices d'hormone de croissance, de preference humaine, et vecteurs pour leur obtention
GB8308235D0 (en) *	1983-03-25	1983-05-05	Celltech Ltd	Polypeptides
US4657894A (en) *	1983-03-31	1987-04-14	Scripps Clinic & Research Foundation	New factor VIII coagulant polypeptides
US4840896A (en) *	1983-11-02	1989-06-20	Integrated Genetics, Inc.	Heteropolymeric protein
EP0466199B1 (en) *	1984-01-12	2002-09-18	Chiron Corporation	Factor VIIIc encoding DNA sequences and related DNA constructs
SE8501050D0 (sv) *	1985-03-05	1985-03-05	Kabivitrum Ab	Biologically active fragments of human antihemophilic factor and method for preparation thereof
MX9203440A (es) *	1985-04-12	1992-07-01	Genetics Inst	Proteinas procoagulantes novedosas.
IL83192A (en) *	1986-07-18	1992-11-15	Gist Brocades Nv	Method for the preparation of proteins with factor viii activity by microbial host cells;expression vectors,host cells,antibodies

1987
- 1987-01-21 FI FI870261A patent/FI98829C/fi not_active IP Right Cessation
- 1987-01-27 DE DE3788289T patent/DE3788289T2/de not_active Expired - Lifetime
- 1987-01-27 EP EP87300695A patent/EP0232112B1/en not_active Expired - Lifetime
- 1987-01-27 JP JP62018141A patent/JPH0797996B2/ja not_active Expired - Fee Related
- 1987-01-27 AU AU68014/87A patent/AU610059B2/en not_active Expired
- 1987-01-27 NO NO870323A patent/NO179106C/no unknown
- 1987-01-27 DK DK198700428A patent/DK175407B1/da not_active IP Right Cessation
- 1987-01-27 AT AT87300695T patent/ATE97956T1/de not_active IP Right Cessation
- 1987-01-27 ES ES87300695T patent/ES2059361T3/es not_active Expired - Lifetime
1993
- 1993-04-20 JP JP5093391A patent/JPH0771496B2/ja not_active Expired - Lifetime
1995
- 1995-03-06 JP JP7045906A patent/JP2513993B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH0771496B2 (ja)	1995-08-02
DE3788289T2 (de)	1994-06-23
EP0232112A2 (en)	1987-08-12
NO179106B (no)	1996-04-29
JPH06205678A (ja)	1994-07-26
JPH0797996B2 (ja)	1995-10-25
DK42887D0 (da)	1987-01-27
FI98829B (fi)	1997-05-15
JP2513993B2 (ja)	1996-07-10
NO870323L (no)	1987-07-28
FI870261L (fi)	1987-07-28
FI98829C (fi)	1997-08-25
EP0232112B1 (en)	1993-12-01
AU610059B2 (en)	1991-05-16
NO179106C (no)	1996-08-07
JPH07278197A (ja)	1995-10-24
ES2059361T3 (es)	1994-11-16
ATE97956T1 (de)	1993-12-15
JPS62282594A (ja)	1987-12-08
DE3788289D1 (de)	1994-01-13
FI870261A0 (fi)	1987-01-21
AU6801487A (en)	1987-07-30
DK175407B1 (da)	2004-09-27
DK42887A (da)	1987-07-28
EP0232112A3 (en)	1987-12-23

Publication	Publication Date	Title
NO870323D0 (no)	1987-01-27	Fremgangsmaate for fremstilling av et rekombinant kompleks med humanfaktor viii:c aktivitet.
DE68929043D1 (de)	1999-09-09	Für androgen-rezeptor-protein kodierende dna
PT85349A (en)	1987-08-01	Method for the preparation of proteins with factor viii activity by microbial host cells expression vectors host cells antibodies
NO874495D0 (no)	1987-10-28	Ekspresjon av protein c.
DK0751992T3 (da)	2006-03-06	Karendotelvækstfaktor 2
NO871785D0 (no)	1987-04-29	Fremgangsmaate for fremstilling av et proteinprodukt, samt vektorsystem for fremgangsmaatens utfoerelse.
OA07233A (fr)	1984-04-30	Interféron immunitaire humain.
NO963358D0 (no)	1996-08-13	Vertsvektor-system til anvendelse i genterapi
ATE87655T1 (de)	1993-04-15	Markierer der t-zelle aktivierung.
NO942456L (no)	1994-06-29	Fremgangsmåte for fremstilling av trombin
ATE71632T1 (de)	1992-02-15	Cdns und gen fuer menschliches angiogenin (angiogenesis-faktor) und expression.
ATE93272T1 (de)	1993-09-15	Expression von protein c.
ATE79403T1 (de)	1992-08-15	Herstellung von thrombin-inhibitoren.
DK110190D0 (da)	1990-05-03	Alveolaere surfaktantproteiner
IL88151A (en)	1993-01-31	Interleukin-7 protein, dna sequences encoding it, its preparation and compositions containing it
DE60043428D1 (de)	2010-01-14	POLYPEPTIDE MIT VERZWEIGUNGSENZYM-AKTIVITäT UND FüR DIESE KODIERENDE NUKLEINSäUREN
DE69837475D1 (de)	2007-05-16	Polypeptide mit aminopeptidaseaktivität und dafür kodierende nukleinsäuren
DE3881023D1 (de)	1993-06-17	Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.
JPS642572A (en)	1989-01-06	Polypeptide, dna and use thereof
ATE127842T1 (de)	1995-09-15	Megakaryocytopoietin, seine herstellung und benutzung.
ATE196165T1 (de)	2000-09-15	Methoden zur herstellung von protein c
DE3877136D1 (de)	1993-02-11	Rekombinantes histidinreiches protein von plasmodium falciparum, seine herstellung und verwendung.