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NO864818L - Fremgangsmaate for fremstilling av nye terapeutisk virksomme tetrahydroisokinolinderivater. - Google Patents

Fremgangsmaate for fremstilling av nye terapeutisk virksomme tetrahydroisokinolinderivater.

Info

Publication number
NO864818L
NO864818L NO864818A NO864818A NO864818L NO 864818 L NO864818 L NO 864818L NO 864818 A NO864818 A NO 864818A NO 864818 A NO864818 A NO 864818A NO 864818 L NO864818 L NO 864818L
Authority
NO
Norway
Prior art keywords
dimethoxyphenyl
formula
cyano
compound
dimethoxy
Prior art date
Application number
NO864818A
Other languages
English (en)
Norwegian (no)
Other versions
NO864818D0 (no
Inventor
Robin D Clark
Joseph M Muchowski
Fang-Ting Chiu
John O Gardner
Jacob Berger
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/803,464 external-priority patent/US4613606A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NO864818D0 publication Critical patent/NO864818D0/no
Publication of NO864818L publication Critical patent/NO864818L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO864818A 1985-12-02 1986-12-01 Fremgangsmaate for fremstilling av nye terapeutisk virksomme tetrahydroisokinolinderivater. NO864818L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/803,464 US4613606A (en) 1985-12-02 1985-12-02 Tetrahydroisoquinoline derivatives
US06/909,659 US4667038A (en) 1985-12-02 1986-09-22 Tetrahydroisoquinoline derivatives

Publications (2)

Publication Number Publication Date
NO864818D0 NO864818D0 (no) 1986-12-01
NO864818L true NO864818L (no) 1987-06-03

Family

ID=27122597

Family Applications (1)

Application Number Title Priority Date Filing Date
NO864818A NO864818L (no) 1985-12-02 1986-12-01 Fremgangsmaate for fremstilling av nye terapeutisk virksomme tetrahydroisokinolinderivater.

Country Status (11)

Country Link
US (1) US4667038A (xx)
EP (1) EP0229944A3 (xx)
KR (1) KR900000672B1 (xx)
CN (1) CN86108089A (xx)
AU (2) AU598772B2 (xx)
DK (1) DK576986A (xx)
FI (1) FI864893L (xx)
HU (1) HU197312B (xx)
IL (1) IL80824A0 (xx)
NO (1) NO864818L (xx)
PL (1) PL262734A1 (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2818890B2 (ja) 1989-09-28 1998-10-30 ダイソー株式会社 アリルアミン化合物の製造方法および同化合物の製造用中間体の製造方法
WO1996006068A1 (en) * 1994-08-22 1996-02-29 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and medicinal use thereof
US5948820A (en) 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
BR0306811A (pt) 2002-01-11 2004-10-26 Sankyo Co Composto, éster farmacologicamente aceitável do mesmo, composição farmacêutica e métodos para prevenção ou tratamento de doenças autoimunes, da artrite reumatóide e da rejeição causada pelo transplante de vários órgãos em um mamìfero
NZ549162A (en) 2004-02-24 2009-12-24 Sankyo Co Amino-pyrrol alcohol compounds
KR100870576B1 (ko) * 2008-08-27 2008-11-27 울산대학교 산학협력단 퇴행성질환 및 염증질환에 대한 예방치료 효과를 갖는 7-하이드록시-6-메톡시-1,2,3,4-테트라하이드로이소퀴놀린 유도체

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1154810B (de) * 1961-04-01 1963-09-26 Knoll Ag Verfahren zur Herstellung basisch substituierter Phenylacetonitrile
DE1802804A1 (de) * 1968-10-12 1970-06-11 Knoll Ag 1-[3'-Cyan-3'-(2'',3''-dimethoxyphenyl)-4'-methylpentyl]-2-methyl-6,7-dimethoxy-1,2,3,4-Tetrahydroisochinolin
US4613606A (en) * 1985-12-02 1986-09-23 Syntex (U.S.A.) Inc. Tetrahydroisoquinoline derivatives

Also Published As

Publication number Publication date
IL80824A0 (en) 1987-03-31
DK576986D0 (da) 1986-12-01
HUT43043A (en) 1987-09-28
FI864893A7 (fi) 1987-06-03
PL262734A1 (en) 1988-07-21
CN86108089A (zh) 1987-09-16
HU197312B (en) 1989-03-28
US4667038A (en) 1987-05-19
AU6584986A (en) 1987-06-04
FI864893L (fi) 1987-06-03
KR870006042A (ko) 1987-07-08
DK576986A (da) 1987-06-03
NO864818D0 (no) 1986-12-01
AU5363090A (en) 1990-09-13
KR900000672B1 (ko) 1990-02-02
AU598772B2 (en) 1990-07-05
EP0229944A3 (en) 1987-10-21
FI864893A0 (fi) 1986-12-01
EP0229944A2 (en) 1987-07-29

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