NO852567L - Thymopentinanaloger og fremgangsmmaate for deres fremstilling. - Google Patents

Thymopentinanaloger og fremgangsmmaate for deres fremstilling.

Info

Publication number: NO852567L
Authority: NO; Norway
Prior art keywords: procedures; preparation; thymopentin; analogs; thymopentin analogs
Prior art date: 1984-06-27

Application number

NO852567A

Other languages

English (en)

Other versions

NO167924B (no

NO167924C (no

Inventor

Gideon Goldstein

George Heavner

Daniel Kroon

Tapan Audhya

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-06-27

Filing date

1985-06-26

Publication date

1985-12-30

1985-06-26 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

1985-12-30 Publication of NO852567L publication Critical patent/NO852567L/no

1991-09-16 Publication of NO167924B publication Critical patent/NO167924B/no

1991-12-27 Publication of NO167924C publication Critical patent/NO167924C/no

Links

PSWFFKRAVBDQEG-YGQNSOCVSA-N thymopentin Chemical class NC(N)=NCCC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 PSWFFKRAVBDQEG-YGQNSOCVSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title 1
101710195641 Splenin Proteins 0.000 abstract 1
102400000160 Thymopentin Human genes 0.000 abstract 1
101800001703 Thymopentin Proteins 0.000 abstract 1
102400000159 Thymopoietin Human genes 0.000 abstract 1
MLKWIQODPVLVLN-SHVFRELUSA-N ac1q1oa8 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)NCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)CNC(=O)CNC(=O)CN)C(C)C)[C@@H](C)O)C(C)C)C(C)C)[C@@H](C)O)C(C)C)C(C)C)C1=CC=C(O)C=C1 MLKWIQODPVLVLN-SHVFRELUSA-N 0.000 abstract 1
230000007812 deficiency Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
230000004957 immunoregulator effect Effects 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
230000002992 thymic effect Effects 0.000 abstract 1
229960004517 thymopentin Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/66—Thymopoietins
- C07K14/662—Thymopoietins at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/18—Thymus derived hormone or factor; related peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Control Of Eletrric Generators (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Control Of Charge By Means Of Generators (AREA)
Control Of Combustion (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

NO852567A 1984-06-27 1985-06-26 Analogifremgangsmaate for fremstilling av terapeutisk aktive thymopentinanaloger NO167924C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/625,344 US4629723A (en)	1984-06-27	1984-06-27	Potent thymopentin analogs

Publications (3)

Publication Number	Publication Date
NO852567L true NO852567L (no)	1985-12-30
NO167924B NO167924B (no)	1991-09-16
NO167924C NO167924C (no)	1991-12-27

Family

ID=24505633

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO852567A NO167924C (no)	1984-06-27	1985-06-26	Analogifremgangsmaate for fremstilling av terapeutisk aktive thymopentinanaloger

Country Status (14)

Country	Link
US (2)	US4629723A (no)
EP (1)	EP0166612B1 (no)
JP (1)	JPH0689029B2 (no)
KR (1)	KR920006563B1 (no)
AT (1)	ATE81135T1 (no)
AU (1)	AU592309B2 (no)
CA (1)	CA1269499A (no)
DE (1)	DE3586697T2 (no)
DK (1)	DK171238B1 (no)
FI (1)	FI92325C (no)
IL (1)	IL75637A (no)
NO (1)	NO167924C (no)
NZ (1)	NZ212461A (no)
ZA (1)	ZA854832B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU602483B2 (en) *	1985-01-18	1990-10-18	Immunetech Pharmaceuticals	Immunoregulatory peptides
DE3619633A1 (de) *	1986-06-11	1987-12-17	Hoechst Ag	Peptide mit einfluss auf die diurese und natriurese, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
HUT46044A (en) *	1986-11-21	1988-09-28	Richter Gedeon Vegyeszet	Process for producing immunstimulant peptides inhibiting multiplication of leukaemic cells and pharmaceutics comprising same
IT1216908B (it) *	1987-03-19	1990-03-14	Eniricerche Spa	Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche.
HU199878B (en) *	1987-06-19	1990-03-28	Berlin Chemie Veb	Process for producing acylated splenopentynes and pharmaceutical compositions comprising such compounds as active ingredient
US5656601A (en) *	1987-06-19	1997-08-12	Berlin-Chemie Ag	Acylated splenopentins, methods for their synthesis and their use
RU2023448C1 (ru) *	1987-07-30	1994-11-30	Сентро Насьональ Де Биопрепарадос	Способ получения вакцины против различных патогенных серотипов менингита нейссера группы в
WO1989009229A1 (en) *	1988-03-31	1989-10-05	Immunobiology Research Institute, Inc.	Treatment of hiv viremic patients with thymopentin
NZ229004A (en)	1988-05-19	1993-09-27	Immunobiology Res Inst Inc	Tetrapeptides having t cell helper acitivity
US4943477A (en) *	1988-09-27	1990-07-24	Mitsubishi Rayon Co., Ltd.	Conductive sheet having electromagnetic interference shielding function
FI902534A7 (fi) *	1988-09-30	1990-05-22	Immunobiology Res Institute Inc	Peptidejä, joilla on T-solusuppressoriaktiivisuutta
US5218089A (en) *	1988-12-23	1993-06-08	Sclavo S.P.A.	Retro-inverso analogues of thymopentin and the method for their synthesis
IT1227908B (it) *	1988-12-23	1991-05-14	Eniricerche S P A Milano Sclav	Nuovi analoghi retro-inversi della timopentina, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche
US5036050A (en) *	1989-01-12	1991-07-30	Immunobiology Research Institute, Inc.	Compositions containing thymopentin for topical treatment of skin disorders
WO1992013546A1 (en) *	1991-02-04	1992-08-20	George Washington University	Mb-40 peptide that enhances the production of interleukin-1 and modulates age-associated immune response
US5492894A (en) *	1991-03-21	1996-02-20	The Procter & Gamble Company	Compositions for treating wrinkles comprising a peptide
US5215964A (en) *	1991-06-03	1993-06-01	Immunobiology Research Institute, Inc.	Peptides useful in regulating the immune and nervous systems
US5928896A (en) *	1993-04-23	1999-07-27	Virginia Commonwealth University	Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
CA2161108A1 (en) *	1993-04-23	1994-11-10	Herbert J. Evans	Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US6258550B1 (en)	1993-04-23	2001-07-10	Virginia Commonwealth University	Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5965698A (en) *	1993-04-23	1999-10-12	Virginia Commonwealth University	Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US5952465A (en) *	1993-04-23	1999-09-14	Virginia Commonwealth University	Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5639729A (en) *	1993-08-26	1997-06-17	Immunobiology Research Institute, Inc.	Tripeptides useful in immune and CNS therapy
US6084066A (en) *	1993-10-29	2000-07-04	Virginia Commonwealth University	Polypetides that include conformation-constraining groups which flank a protein-protein interaction site
FR2741076B1 (fr) *	1995-11-15	1998-01-30	Rech De Pathologie Appliquee S	Conjugues peptidiques derives des hormones thymiques, leur utilisation a titre de medicament et compositions les contenant
CN101168560B (zh) *	2006-10-23	2012-09-05	江苏正大天晴药业股份有限公司	N-取代肽酰胺，其药物组合物与用途
CN116712571B (zh) *	2021-12-16	2024-01-30	江西中医药大学	一种新型环肽在制备肿瘤诊断和或治疗试剂中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4077949A (en) *	1973-12-28	1978-03-07	Sloan-Kettering Institute For Cancer Research	Polypeptide hormones of the thymus
US4002740A (en) *	1975-08-21	1977-01-11	Gideon Goldstein	Tridecapeptide compositions and methods
US4190646A (en) *	1975-11-11	1980-02-26	Sloan-Kettering Institute For Cancer Research	Polypeptide compositions and methods
SE446867B (sv) *	1977-11-15	1986-10-13	Sloan Kettering Inst Cancer	Sett att framstella en polypeptid med formaga att inducera differentiering av t-lymfocyter men inte av komplementreceptor (cr?72+) b-lymfocyter
CA1157466A (en) *	1979-04-12	1983-11-22	Gideon Goldstein	Peptides having thymopoietin-like activity
ZA802170B (en) *	1979-04-12	1981-11-25	Ortho Pharma Corp	Peptides having thymopoietin-like activity
US4261886A (en) *	1980-03-13	1981-04-14	Ortho Pharmaceutical Corporation	Peptides having thymopoietin-like activity
DE2938420A1 (de) *	1979-09-22	1981-04-09	Hoechst Ag, 6000 Frankfurt	Neue peptide und verfahren zu ihrer herstellung
US4309340A (en) *	1980-03-31	1982-01-05	American Home Products Corporation	Polypeptide compositions
US4361673A (en) *	1980-09-19	1982-11-30	American Home Products Corporation	Polypeptide compositions
US4305852A (en) *	1980-10-20	1981-12-15	American Home Products Corporation	Polypeptide compositions
US4505853A (en) *	1983-11-18	1985-03-19	Ortho Pharmaceutical Corporation	Enzyme-resistant immunomodulatory peptides
DE3421614A1 (de) *	1984-06-09	1985-12-12	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von pentapeptiden mit wirkung auf das immunsystem und zwischenprodukte dieses verfahrens

1984
- 1984-06-27 US US06/625,344 patent/US4629723A/en not_active Ceased
1985
- 1985-06-18 NZ NZ212461A patent/NZ212461A/xx unknown
- 1985-06-26 NO NO852567A patent/NO167924C/no unknown
- 1985-06-26 EP EP85304559A patent/EP0166612B1/en not_active Expired - Lifetime
- 1985-06-26 ZA ZA854832A patent/ZA854832B/xx unknown
- 1985-06-26 KR KR1019850004553A patent/KR920006563B1/ko not_active Expired
- 1985-06-26 IL IL75637A patent/IL75637A/xx not_active IP Right Cessation
- 1985-06-26 FI FI852522A patent/FI92325C/fi not_active IP Right Cessation
- 1985-06-26 CA CA000485260A patent/CA1269499A/en not_active Expired - Lifetime
- 1985-06-26 DK DK289285A patent/DK171238B1/da not_active IP Right Cessation
- 1985-06-26 AT AT85304559T patent/ATE81135T1/de not_active IP Right Cessation
- 1985-06-26 AU AU44215/85A patent/AU592309B2/en not_active Expired
- 1985-06-26 DE DE8585304559T patent/DE3586697T2/de not_active Expired - Lifetime
- 1985-06-27 JP JP60141464A patent/JPH0689029B2/ja not_active Expired - Lifetime
1990
- 1990-04-25 US US07/514,184 patent/USRE34165E/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
FI852522L (fi)	1985-12-28
EP0166612B1 (en)	1992-09-30
CA1269499A (en)	1990-05-22
EP0166612A2 (en)	1986-01-02
US4629723A (en)	1986-12-16
ZA854832B (en)	1987-02-25
NZ212461A (en)	1988-10-28
NO167924B (no)	1991-09-16
DE3586697D1 (en)	1992-11-05
AU592309B2 (en)	1990-01-11
FI852522A0 (fi)	1985-06-26
KR920006563B1 (ko)	1992-08-08
JPS6118799A (ja)	1986-01-27
DK171238B1 (da)	1996-08-05
FI92325B (fi)	1994-07-15
FI92325C (fi)	1994-10-25
ATE81135T1 (de)	1992-10-15
DK289285D0 (da)	1985-06-26
IL75637A (en)	1990-02-09
EP0166612A3 (en)	1987-08-05
DK289285A (da)	1985-12-28
DE3586697T2 (de)	1993-02-11
USRE34165E (en)	1993-01-19
NO167924C (no)	1991-12-27
JPH0689029B2 (ja)	1994-11-09
IL75637A0 (en)	1985-10-31
AU4421585A (en)	1986-01-02
KR860000314A (ko)	1986-01-28

Publication	Publication Date	Title
NO852567L (no)	1985-12-30	Thymopentinanaloger og fremgangsmmaate for deres fremstilling.
EP0165033A3 (en)	1988-04-27	Conformationally restricted thymopentin-like compounds
IT8321083A0 (it)	1983-05-13	Analoghi retro-invertiti del pentapeptide potenziante la bradichinina bpp5a e metodi per laloro preparazione.
NO872712D0 (no)	1987-06-29	Fremgangsmaate for fremstilling av kalsiumholdige preparater.
NO873183L (no)	1988-02-01	Fremgangsmaate til fremstilling av reninhemmende di- og tri-peptider.
IT8522564A0 (it)	1985-10-21	Procedimento per la preparazione di idroalofluoroalcani.
DK482185A (da)	1986-04-23	Peptider, deres fremstilling og anvendelse som laegemidler
IT1230068B (it)	1991-10-05	Procedimento per la preparazione di n sulfoniluree.
FI872659A7 (fi)	1987-12-21	Menetelmä uusien androst-4-eeni-3,17-dionien valmistamiseksi.
NO864514D0 (no)	1986-11-12	Fremgangsmaate for fremstilling av thiazoloner.
IT8567535A1 (it)	1986-12-07	Procedimento per la preparazione di amminoidrossicefamcarbossilati.
IT8522365A0 (it)	1985-10-04	Procedimento per la preparazione di l-alfa-glicerilfosforilcolina, l-alfa-glicerilfosforiletanolommina e l-alfa-glicerilfosforilinositolo da lecitine grezze e/o deoleate.
BG90414A (bg)	1993-12-24	2-азабицикло (2,2,1)-хепт-5- ен-2-оцетна киселина и нейни производни, метод за получаване и приложението им
ES2019594B3 (es)	1991-07-01	Metodo de tamponado del ph.
IT8619206A0 (it)	1986-01-28	Procedimento per la preparazione di 4,4-dialchil-2-azetidinoni.
IT8723035A0 (it)	1987-12-16	Procedimento per la preparazione di n acilaniline.
FI882887A0 (fi)	1988-06-16	Foer klaeder avsedd tvaett- och/eller torkmaskin, vars trumma staengs med regel.
IT8321507A0 (it)	1983-06-07	Procedimento di preparazione fermentativa di l-leucina.
IT8720078A0 (it)	1987-04-10	Procedimento per la preparazione di (+)-13-norfaranale.
IT8620754A0 (it)	1986-06-11	Procedimento per la preparazione di chinoni.
IT1228559B (it)	1991-06-21	Procedimento per la preparazione di enzima mieloperossidasi.
DE3682368D1 (de)	1991-12-12	Mitogene peptide.
BG40657A3 (en)	1987-01-15	Method for preparing derivatives of a- 21978c cyclic peptides
FI863109A7 (fi)	1988-01-31	Menetelmä monoterpeenien erottamiseksi.
NO875186D0 (no)	1987-12-11	Liggeunderlag for bestraalingsenheter.