NO854001L - 1-pyridinyl-2(dialkylamino)etenylalkylketon-mellomprodukter for bruk ved fremstilling av kardiotonisk virksomme 2(1h)-pyridinoner. - Google Patents

1-pyridinyl-2(dialkylamino)etenylalkylketon-mellomprodukter for bruk ved fremstilling av kardiotonisk virksomme 2(1h)-pyridinoner.

Info

Publication number: NO854001L
Authority: NO; Norway
Prior art keywords: ethenylalkylketon; pyridinones; dialkylamino; pyridinyl; preparation
Prior art date: 1979-11-26

Application number

NO854001A

Other languages

English (en)

Other versions

NO156127C (no

NO156127B (no

Inventor

George Yohe Lesher

Richard Everett Philion

Donald Frederick Page

Chester Joseph Opalka Jr

Original Assignee

Sterling Drug Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-11-26

Filing date

1985-10-09

Publication date

1981-05-27

1980-03-28 Priority claimed from US06/135,100 external-priority patent/US4297360A/en

1980-10-20 Priority claimed from US06/198,461 external-priority patent/US4313951A/en

1981-05-27 Publication of NO854001L publication Critical patent/NO854001L/no

1985-10-09 Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc

1987-04-21 Publication of NO156127B publication Critical patent/NO156127B/no

1987-07-29 Publication of NO156127C publication Critical patent/NO156127C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO85854001A 1979-11-26 1985-10-09 1-pyridinyl-2(dialkylamino)-etenylalkylketoner. NO156127C (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US9750479A	1979-11-26	1979-11-26
US06/135,100 US4297360A (en)	1980-03-28	1980-03-28	5-(Pyridinyl)pyridine-2,3-diamines, preparation thereof and their cardiotonic use
US06/198,461 US4313951A (en)	1979-11-26	1980-10-20	3-Substituted-6-(lower-alkyl)-5-(pyridinyl)-2(1H)-pyridinones, their cardiotonic use and intermediates therefor
US06/204,726 US4312875A (en)	1980-03-28	1980-11-06	5-(Pyridinyl)-6-(lower-alkyl)-2(1H)-pyridinones, 1,2-dihydro-2-oxo-5-(pyridinyl)-6-(lower-alkyl)nicotinic acids and lower-alkyl esters thereof, and cardiotonic use thereof

Publications (3)

Publication Number	Publication Date
NO854001L true NO854001L (no)	1981-05-27
NO156127B NO156127B (no)	1987-04-21
NO156127C NO156127C (no)	1987-07-29

Family

ID=27492921

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO803550A NO154345C (no)	1979-11-26	1980-11-25	Analogifremgangsmaate for fremstilling av kardiotonisk virksomme 5-(pyridinyl)-2(1h)-pyridinoner.
NO85854001A NO156127C (no)	1979-11-26	1985-10-09	1-pyridinyl-2(dialkylamino)-etenylalkylketoner.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
NO803550A NO154345C (no)	1979-11-26	1980-11-25	Analogifremgangsmaate for fremstilling av kardiotonisk virksomme 5-(pyridinyl)-2(1h)-pyridinoner.

Country Status (20)

Country	Link
AT (1)	AT379387B (no)
CH (1)	CH649535A5 (no)
DE (1)	DE3044568A1 (no)
DK (1)	DK151799C (no)
ES (1)	ES507620A0 (no)
FI (1)	FI76564C (no)
FR (2)	FR2470124B1 (no)
GB (2)	GB2065642B (no)
GR (1)	GR71608B (no)
HK (2)	HK31189A (no)
IE (1)	IE50632B1 (no)
IL (2)	IL61501A (no)
IT (1)	IT1148740B (no)
LU (1)	LU82957A1 (no)
MX (1)	MX155904A (no)
NL (2)	NL192202C (no)
NO (2)	NO154345C (no)
NZ (1)	NZ195564A (no)
PT (1)	PT72106B (no)
SE (1)	SE442398B (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4305948A (en) *	1980-12-22	1981-12-15	Sterling Drug Inc.	N-Hydroxy-1,2-dihydro-2-oxo-5-(pyridinyl)-nicotinimidamide and their cardiotonic use
US4465686A (en) *	1981-09-08	1984-08-14	Sterling Drug Inc.	5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation
FR2529891A1 (fr) *	1982-07-12	1984-01-13	Nativelle Sa Ets	Derives du pyridyl-3 alcoxy-5 pyrazole, procede de preparation et application en therapeutique
IL69407A (en) *	1982-08-23	1987-10-20	Warner Lambert Co	2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them
IL70169A0 (en) *	1982-11-18	1984-02-29	Sterling Drug Inc	2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them
GB8414220D0 (en) *	1984-06-04	1984-07-11	Sterwin Ag	Medicaments in unit dose form
EP0544812B1 (en) *	1990-08-21	1995-04-05	The Upjohn Company	Bisphosphonic acid derivatives as anti-arthritic agents
CZ403592A3 (en) *	1992-02-20	1993-12-15	Hoechst Ag	Arylcarbonylaminoalkyldihydrooxopyridines, process of their preparation and their use
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
JP2008524233A (ja) *	2004-12-16	2008-07-10	バーテックスファーマシューティカルズインコーポレイテッド	炎症性疾患、増殖性疾患および免疫介在性疾患の治療のためのｔｅｃファミリータンパク質キナーゼのインヒビターとして有用なピリド−２−オン
RU2008122978A (ru)	2005-11-09	2009-12-20	Комбинаторкс, Инкорпорейтед (Us)	Способы, композиции и наборы для лечения медицинских состояний
CA2688161C (en)	2007-06-04	2020-10-20	Kunwar Shailubhai	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2328910B1 (en)	2008-06-04	2014-08-06	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP3241839B1 (en)	2008-07-16	2019-09-04	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
DK2681236T3 (en)	2011-03-01	2018-04-16	Synergy Pharmaceuticals Inc	PROCEDURE FOR MANUFACTURING GUANYLATE CYCLASE-C-AGONISTS
EP3718546A1 (en)	2011-08-16	2020-10-07	Cardiora Pty Ltd	Controlled-release formulation
US20150119399A1 (en)	2012-01-10	2015-04-30	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
CA2902348C (en)	2013-02-25	2021-11-30	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
HK1220611A1 (zh)	2013-03-15	2017-05-12	Bausch Health Ireland Limited	用於治疗胃肠道病症的组成物
WO2014151206A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
CN113388007A (zh)	2013-06-05	2021-09-14	博士医疗爱尔兰有限公司	鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
BR112016002789A2 (pt)	2013-08-09	2017-11-21	Ardelyx Inc	compostos e métodos para inibir transporte de fosfato
EP3236963B1 (en)	2014-12-22	2020-01-29	Cardiora Pty Ltd	Method of treatment
WO2020237096A1 (en)	2019-05-21	2020-11-26	Ardelyx, Inc.	Combination for lowering serum phosphate in a patient

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4004012A (en) *	1975-10-14	1977-01-18	Sterling Drug Inc.	3-Cyano-5-(pyridinyl)-2(1H)-pyridinones
US4072746A (en) *	1975-10-14	1978-02-07	Sterling Drug Inc.	3-Amino-5-(pyridinyl)-2(1H)-pyridinones

1980
- 1980-11-17 NZ NZ195564A patent/NZ195564A/xx unknown
- 1980-11-17 IL IL61501A patent/IL61501A/xx not_active IP Right Cessation
- 1980-11-18 MX MX9577A patent/MX155904A/es unknown
- 1980-11-24 FI FI803652A patent/FI76564C/fi not_active IP Right Cessation
- 1980-11-24 IE IE2430/80A patent/IE50632B1/en not_active IP Right Cessation
- 1980-11-24 NL NL8006399A patent/NL192202C/nl not_active IP Right Cessation
- 1980-11-25 IT IT26218/80A patent/IT1148740B/it active
- 1980-11-25 SE SE8008252A patent/SE442398B/sv not_active IP Right Cessation
- 1980-11-25 NO NO803550A patent/NO154345C/no unknown
- 1980-11-25 DK DK501180A patent/DK151799C/da not_active IP Right Cessation
- 1980-11-25 FR FR8024998A patent/FR2470124B1/fr not_active Expired
- 1980-11-25 PT PT72106A patent/PT72106B/pt unknown
- 1980-11-26 AT AT0578080A patent/AT379387B/de not_active IP Right Cessation
- 1980-11-26 LU LU82957A patent/LU82957A1/fr unknown
- 1980-11-26 GB GB8037856A patent/GB2065642B/en not_active Expired
- 1980-11-26 DE DE19803044568 patent/DE3044568A1/de active Granted
- 1980-11-26 GR GR63461A patent/GR71608B/el unknown
- 1980-11-26 CH CH8783/80A patent/CH649535A5/fr not_active IP Right Cessation
1981
- 1981-12-01 ES ES507620A patent/ES507620A0/es active Granted
1983
- 1983-06-10 GB GB08315983A patent/GB2131421B/en not_active Expired
- 1983-09-28 IL IL69847A patent/IL69847A0/xx unknown
1984
- 1984-10-25 FR FR8416357A patent/FR2553767B1/fr not_active Expired
1985
- 1985-10-09 NO NO85854001A patent/NO156127C/no unknown
1989
- 1989-04-13 HK HK311/89A patent/HK31189A/xx not_active IP Right Cessation
1990
- 1990-10-11 HK HK830/90A patent/HK83090A/xx not_active IP Right Cessation
1997
- 1997-07-24 NL NL970028C patent/NL970028I2/nl unknown

Also Published As

Publication number	Publication date
ES8301920A1 (es)	1982-11-16
SE8008252L (sv)	1981-05-27
NL970028I2 (nl)	1998-03-02
IT1148740B (it)	1986-12-03
LU82957A1 (fr)	1981-06-04
GB2065642B (en)	1984-04-04
FR2470124A1 (fr)	1981-05-29
HK31189A (en)	1989-04-21
NL192202B (nl)	1996-11-01
IE802430L (en)	1981-05-26
NZ195564A (en)	1983-09-30
GB2131421A (en)	1984-06-20
NL970028I1 (nl)	1997-10-01
HK83090A (en)	1990-10-19
SE442398B (sv)	1985-12-23
NO156127C (no)	1987-07-29
GR71608B (no)	1983-06-17
FR2553767B1 (fr)	1987-01-16
IL69847A0 (en)	1983-12-30
DK151799C (da)	1988-06-20
CH649535A5 (fr)	1985-05-31
FI76564B (fi)	1988-07-29
PT72106B (fr)	1981-09-29
IL61501A (en)	1984-06-29
DE3044568C2 (no)	1990-11-29
GB2065642A (en)	1981-07-01
NO154345B (no)	1986-05-26
FI803652L (fi)	1981-05-27
NO156127B (no)	1987-04-21
ES507620A0 (es)	1982-11-16
PT72106A (fr)	1980-12-01
NO803550L (no)	1981-05-27
FR2553767A1 (fr)	1985-04-26
DE3044568A1 (de)	1981-08-27
FI76564C (fi)	1988-11-10
FR2470124B1 (fr)	1986-12-19
IL61501A0 (en)	1981-05-20
MX155904A (es)	1988-05-23
IE50632B1 (en)	1986-05-28
IT8026218A0 (it)	1980-11-25
NL192202C (nl)	1997-03-04
AT379387B (de)	1985-12-27
NL8006399A (nl)	1981-06-16
ATA578080A (de)	1985-05-15
DK151799B (da)	1988-01-04
GB2131421B (en)	1985-06-26
GB8315983D0 (en)	1983-07-13
NO154345C (no)	1986-09-03
DK501180A (da)	1981-05-27

Publication	Publication Date	Title
NO854001L (no)	1981-05-27	1-pyridinyl-2(dialkylamino)etenylalkylketon-mellomprodukter for bruk ved fremstilling av kardiotonisk virksomme 2(1h)-pyridinoner.
NO792787L (no)	1980-03-03	Fremgangsmaate ved fremstilling av antiinflammatorisk aktive 4,5-diaryl-2-nitroimidazoler
NO149389C (no)	1984-04-11	Fremgangsmaate til fremstilling av 4,1`,6`-triklor-4,1`,6`-trideoksy-galaktosukrose
NO801155L (no)	1980-10-24	Fremgangsmaate ved fremstilling av acyl-carnitinamider
NO790257L (no)	1979-07-27	Fremgangsmaate ved fremstilling av 9-desoksy-9a-metylen-isostere av pgi2
NO801690L (no)	1980-12-09	Fremgangsmaate ved fremstilling av pankreatin-pellets
NO802546L (no)	1981-03-02	Fremgangsmaate ved fremstilling av beta-carbolin-3-carboxylsyre-derivater.
NO794327L (no)	1980-07-07	Fremgangsmaate ved fremstilling av nye peptidylargininaldehyd-derivater.
NO802913L (no)	1981-04-03	Fremgangsmaate ved fremstilling av cephalosporinforbindelse
NO794069L (no)	1980-06-16	Fremgangsmaate ved fremstilling av terapeutisk virksomme imidayolderivater.
TR20867A (tr)	1982-11-09	Yeni substituee nitrodifenil eterler,bunlari havi olan herbisid bilesimler,bunlarin ihzarina mahsus usuller ve yabani otlarla muecadelede kullanimi
NO802384L (no)	1981-02-10	Fremgangsmaate ved fremstilling av antiinflammatorisk virksomme 5-substituerte 2,3-diarylthiofener
NO793804L (no)	1980-05-28	Fremgangsmaate ved fremstilling av slipemasse.
NO153431C (no)	1986-03-19	Fremgangsmaate ved fremstilling av 6alfa-halogen-3-keto-delta1,4-pregnadiener.
NL183898B (nl)	1988-09-16	Werkwijze voor de bereiding van cefamycine c.
NO801179L (no)	1980-10-27	Fremgangsmaate ved fremstilling av 2`,6`-dialkyl-n-alkoxymethyl-2-klor-acetanilider
NO160205C (no)	1989-03-22	Fremgangsmaate ved fremstilling av silibininderivater.
NO794199L (no)	1980-07-14	Fremgangsmaate for fremstilling av spinnflor.
NO154795C (no)	1986-12-29	Analogifremgangsmaate ved fremstilling av terapeutisk virksomme 1,2,4-oxadiazolin-5-on-derivater.
NO801142L (no)	1980-10-28	Fremgangsmaate til fremstilling av klordioksyd.
NL7810456A (nl)	1979-04-23	Werkwijze voor het bereiden van 6,11-dihydro-11-oxodi- benz (b,e)-oxepine-2-azijnzuur en tussenprodukten daarvoor.
NO802324L (no)	1981-02-03	Fremgangsmaate ved fremstilling av 3-amino-1-benzoxepin-5(2h)-derivater.
RO75739A (ro)	1981-02-28	Procedeu pentru prepararea unor carbamoil triazolil-o,n-acetali
NO790328L (no)	1979-08-03	Fremgangsmaate ved fremstilling av derivater av nafthyl-1-eddiksyre.
NO153100C (no)	1986-01-15	Fremgangsmaate ved fremstilling av n-(halogenmethyl)-acylamider.