NO811943L - Fremgangsmaate til fremstilling av encelleprotein med lavt nukleinsyreinnhold - Google Patents
Fremgangsmaate til fremstilling av encelleprotein med lavt nukleinsyreinnholdInfo
- Publication number
- NO811943L NO811943L NO811943A NO811943A NO811943L NO 811943 L NO811943 L NO 811943L NO 811943 A NO811943 A NO 811943A NO 811943 A NO811943 A NO 811943A NO 811943 L NO811943 L NO 811943L
- Authority
- NO
- Norway
- Prior art keywords
- protein
- range
- nucleic acid
- scp
- microorganism
- Prior art date
Links
- 102000039446 nucleic acids Human genes 0.000 title claims description 99
- 108020004707 nucleic acids Proteins 0.000 title claims description 99
- 238000000034 method Methods 0.000 title claims description 36
- -1 LOW NUCLEIC ACID Chemical class 0.000 title description 2
- 108010027322 single cell proteins Proteins 0.000 claims description 112
- 150000007523 nucleic acids Chemical class 0.000 claims description 98
- 230000004151 fermentation Effects 0.000 claims description 28
- 244000005700 microbiome Species 0.000 claims description 28
- 238000000855 fermentation Methods 0.000 claims description 26
- 239000007800 oxidant agent Substances 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- 241000894007 species Species 0.000 claims description 16
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 15
- 239000007900 aqueous suspension Substances 0.000 claims description 15
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical group OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 14
- 229910001868 water Inorganic materials 0.000 claims description 14
- 241000235058 Komagataella pastoris Species 0.000 claims description 13
- 241000894006 Bacteria Species 0.000 claims description 11
- 241000235648 Pichia Species 0.000 claims description 11
- 239000012530 fluid Substances 0.000 claims description 10
- 241000222120 Candida <Saccharomycetales> Species 0.000 claims description 8
- 230000000813 microbial effect Effects 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 6
- 241000320412 Ogataea angusta Species 0.000 claims description 5
- 241000186063 Arthrobacter Species 0.000 claims description 4
- 241000193830 Bacillus <bacterium> Species 0.000 claims description 4
- 241000186216 Corynebacterium Species 0.000 claims description 4
- 241000586779 Protaminobacter Species 0.000 claims description 4
- 241000589516 Pseudomonas Species 0.000 claims description 4
- 241000235070 Saccharomyces Species 0.000 claims description 4
- 230000001580 bacterial effect Effects 0.000 claims description 4
- XXQBEVHPUKOQEO-UHFFFAOYSA-N potassium superoxide Chemical compound [K+].[K+].[O-][O-] XXQBEVHPUKOQEO-UHFFFAOYSA-N 0.000 claims description 4
- 230000008569 process Effects 0.000 claims description 4
- 241000192041 Micrococcus Species 0.000 claims description 3
- 241000589220 Acetobacter Species 0.000 claims description 2
- 241000590020 Achromobacter Species 0.000 claims description 2
- 241000186046 Actinomyces Species 0.000 claims description 2
- 241000722885 Brettanomyces Species 0.000 claims description 2
- 241000186146 Brevibacterium Species 0.000 claims description 2
- 239000004343 Calcium peroxide Substances 0.000 claims description 2
- 241001337994 Cryptococcus <scale insect> Species 0.000 claims description 2
- 241000235035 Debaryomyces Species 0.000 claims description 2
- 241001465321 Eremothecium Species 0.000 claims description 2
- 241001149698 Lipomyces Species 0.000 claims description 2
- SPAGIJMPHSUYSE-UHFFFAOYSA-N Magnesium peroxide Chemical compound [Mg+2].[O-][O-] SPAGIJMPHSUYSE-UHFFFAOYSA-N 0.000 claims description 2
- 241000589350 Methylobacter Species 0.000 claims description 2
- 241000589345 Methylococcus Species 0.000 claims description 2
- 241000589966 Methylocystis Species 0.000 claims description 2
- 241000589354 Methylosinus Species 0.000 claims description 2
- 241001467578 Microbacterium Species 0.000 claims description 2
- 241000186359 Mycobacterium Species 0.000 claims description 2
- 241000187654 Nocardia Species 0.000 claims description 2
- 241000190932 Rhodopseudomonas Species 0.000 claims description 2
- LHJQIRIGXXHNLA-UHFFFAOYSA-N calcium peroxide Chemical compound [Ca+2].[O-][O-] LHJQIRIGXXHNLA-UHFFFAOYSA-N 0.000 claims description 2
- 235000019402 calcium peroxide Nutrition 0.000 claims description 2
- 229960004995 magnesium peroxide Drugs 0.000 claims description 2
- 230000003647 oxidation Effects 0.000 claims description 2
- 238000007254 oxidation reaction Methods 0.000 claims description 2
- PFUVRDFDKPNGAV-UHFFFAOYSA-N sodium peroxide Chemical compound [Na+].[Na+].[O-][O-] PFUVRDFDKPNGAV-UHFFFAOYSA-N 0.000 claims description 2
- 241000589344 Methylomonas Species 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 235000018102 proteins Nutrition 0.000 description 52
- 108090000623 proteins and genes Proteins 0.000 description 52
- 102000004169 proteins and genes Human genes 0.000 description 52
- 238000011282 treatment Methods 0.000 description 38
- 239000000047 product Substances 0.000 description 35
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 29
- 235000011114 ammonium hydroxide Nutrition 0.000 description 29
- 239000000908 ammonium hydroxide Substances 0.000 description 27
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 24
- 150000002978 peroxides Chemical group 0.000 description 19
- 210000004027 cell Anatomy 0.000 description 17
- 239000000203 mixture Substances 0.000 description 14
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 11
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 10
- 238000010564 aerobic fermentation Methods 0.000 description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- 238000005119 centrifugation Methods 0.000 description 9
- 239000007787 solid Substances 0.000 description 9
- 239000011707 mineral Substances 0.000 description 8
- 235000010755 mineral Nutrition 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 241000282414 Homo sapiens Species 0.000 description 7
- 230000009467 reduction Effects 0.000 description 7
- 150000003839 salts Chemical class 0.000 description 7
- 241000282412 Homo Species 0.000 description 6
- 235000005911 diet Nutrition 0.000 description 6
- 230000037213 diet Effects 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 6
- 229910052500 inorganic mineral Inorganic materials 0.000 description 6
- 239000002609 medium Substances 0.000 description 6
- 239000006228 supernatant Substances 0.000 description 6
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 5
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 5
- 235000001014 amino acid Nutrition 0.000 description 5
- 150000001413 amino acids Chemical class 0.000 description 5
- 229910021529 ammonia Inorganic materials 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 229910052757 nitrogen Inorganic materials 0.000 description 5
- 229940116269 uric acid Drugs 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 239000002002 slurry Substances 0.000 description 4
- 239000011573 trace mineral Substances 0.000 description 4
- 235000013619 trace mineral Nutrition 0.000 description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 235000014633 carbohydrates Nutrition 0.000 description 3
- 150000001720 carbohydrates Chemical class 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 3
- 230000035484 reaction time Effects 0.000 description 3
- 239000012265 solid product Substances 0.000 description 3
- 239000007921 spray Substances 0.000 description 3
- 238000001694 spray drying Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 210000005253 yeast cell Anatomy 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 description 2
- 102000003839 Human Proteins Human genes 0.000 description 2
- 108090000144 Human Proteins Proteins 0.000 description 2
- 241000364057 Peoria Species 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000002421 cell wall Anatomy 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000008367 deionised water Substances 0.000 description 2
- 229910021641 deionized water Inorganic materials 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- ZSIAUFGUXNUGDI-UHFFFAOYSA-N hexan-1-ol Chemical compound CCCCCCO ZSIAUFGUXNUGDI-UHFFFAOYSA-N 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- RVLOMLVNNBWRSR-KNIFDHDWSA-N (2s)-2-aminopropanoic acid;(2s)-2,6-diaminohexanoic acid Chemical compound C[C@H](N)C(O)=O.NCCCC[C@H](N)C(O)=O RVLOMLVNNBWRSR-KNIFDHDWSA-N 0.000 description 1
- PAWQVTBBRAZDMG-UHFFFAOYSA-N 2-(3-bromo-2-fluorophenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC(Br)=C1F PAWQVTBBRAZDMG-UHFFFAOYSA-N 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 239000004097 EU approved flavor enhancer Substances 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 210000000712 G cell Anatomy 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 108010092464 Urate Oxidase Proteins 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 229940098773 bovine serum albumin Drugs 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000010835 comparative analysis Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000004699 copper complex Chemical class 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 235000021245 dietary protein Nutrition 0.000 description 1
- 230000007071 enzymatic hydrolysis Effects 0.000 description 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000019264 food flavour enhancer Nutrition 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000003630 growth substance Substances 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 229910017053 inorganic salt Inorganic materials 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229910000357 manganese(II) sulfate Inorganic materials 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 150000002897 organic nitrogen compounds Chemical class 0.000 description 1
- 230000020477 pH reduction Effects 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 235000011149 sulphuric acid Nutrition 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C12N1/18—Baker's yeast; Brewer's yeast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/005—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor after treatment of microbial biomass not covered by C12N1/02 - C12N1/08
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/08—Reducing the nucleic acid content
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/32—Processes using, or culture media containing, lower alkanols, i.e. C1 to C6
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Sustainable Development (AREA)
- Botany (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15818180A | 1980-06-10 | 1980-06-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO811943L true NO811943L (no) | 1981-12-11 |
Family
ID=22566985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO811943A NO811943L (no) | 1980-06-10 | 1981-06-09 | Fremgangsmaate til fremstilling av encelleprotein med lavt nukleinsyreinnhold |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0041650A3 (es) |
| JP (1) | JPS5747478A (es) |
| KR (1) | KR830006418A (es) |
| DK (1) | DK251381A (es) |
| ES (1) | ES502794A0 (es) |
| GB (1) | GB2078754A (es) |
| NO (1) | NO811943L (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4601986A (en) * | 1983-07-29 | 1986-07-22 | Phillips Petroleum Company | Protein product of reduced nucleic acid content and low allergenicity |
| IL95019A0 (en) * | 1989-08-09 | 1991-06-10 | Mycogen Corp | Process for encapsulation of biologicals |
| TR27620A (tr) * | 1991-12-13 | 1995-06-13 | Procter & Gamble | Sivilarin mikro-organizmalar icinde kapsüllenmesi. |
| AU664050B2 (en) * | 1991-12-18 | 1995-11-02 | Becton Dickinson & Company | Process for lysing mycobacteria |
| EP0805201B1 (en) * | 1995-05-29 | 2000-01-12 | Otkrytoe Akcionernoe Obschestvo"Nauchno-Issledovatelsky Institut Vychislitelnykh Komplexov im. M.A. Karceva", | Method of obtaining a biomass of microorganisms with a low nucleic acids content |
| KR101677042B1 (ko) * | 2014-04-01 | 2016-11-17 | 대한민국 | 효모 균주로부터 수산화 암모늄을 전처리하여 단백질을 추출하는 방법 |
| WO2023089548A1 (en) * | 2021-11-22 | 2023-05-25 | Superbrewed Food Inc. | Methods for reduction of bacterial nucleic acid content |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3775393A (en) * | 1970-12-03 | 1973-11-27 | Standard Oil Co | Ammonia extraction of unicellular microorganisms |
| GB1400691A (en) * | 1973-02-08 | 1975-07-23 | British Petroleum Co | Process for the production of proteinaceous material |
| US3947605A (en) * | 1974-10-30 | 1976-03-30 | Standard Oil Company | Process for preparing high yields of single cell products having reduced purine content and high nutritive value |
| GB1552420A (en) * | 1975-09-19 | 1979-09-12 | British Petroleum Co | Process for treating single cell protein to the colour |
| US4206243A (en) * | 1976-07-27 | 1980-06-03 | Hoechst Aktiengesellschaft | Process for reducing the contents of lipids and nucleic acid in microbial cell masses |
-
1981
- 1981-05-27 EP EP81104071A patent/EP0041650A3/en not_active Withdrawn
- 1981-06-05 JP JP56086750A patent/JPS5747478A/ja active Pending
- 1981-06-05 ES ES502794A patent/ES502794A0/es active Granted
- 1981-06-08 KR KR1019810002041A patent/KR830006418A/ko not_active Ceased
- 1981-06-09 DK DK251381A patent/DK251381A/da not_active Application Discontinuation
- 1981-06-09 NO NO811943A patent/NO811943L/no unknown
- 1981-06-10 GB GB8117835A patent/GB2078754A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0041650A3 (en) | 1982-05-12 |
| KR830006418A (ko) | 1983-09-24 |
| DK251381A (da) | 1981-12-11 |
| GB2078754A (en) | 1982-01-13 |
| ES8300851A1 (es) | 1982-04-01 |
| ES502794A0 (es) | 1982-04-01 |
| JPS5747478A (en) | 1982-03-18 |
| EP0041650A2 (en) | 1981-12-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Matelbs et al. | Single-cell protein | |
| Arasaratnam et al. | Supplementation of whey with glucose and different nitrogen sources for lactic acid production by Lactobacillus delbrueckii | |
| Amrane et al. | Influence of yeast extract concentrationon batch cultures of Lactobacillus helveticus: growth and production coupling | |
| US4501765A (en) | Production of edible protein-containing substances | |
| US5700684A (en) | Process for preparing a biomass, use of the biomass so prepared, and panification ferment | |
| US4786598A (en) | Process for the biotechnological preparation of poly-d-(-)-3-hydroxybutyric acid | |
| NO161810B (no) | Fremgangsmaate for fremstilling av invertasefri alfa-galaktosidase og anvendelse av denne for hydrolysering av soyaboenne-oligosakkarider. | |
| Ruiz-Barba et al. | Availability of essential B-group vitamins to Lactobacillus plantarum in green olive fermentation brines | |
| US4008334A (en) | Process for removal of water-soluble carbohydrates in the production of plant protein products | |
| US3775393A (en) | Ammonia extraction of unicellular microorganisms | |
| US4957861A (en) | Process for the biotechnological preparation of poly-D-(-)-3-hydroxybutyric acid | |
| NO813565L (no) | Fremstilling av protein med redusert nukleinsyreinnhold | |
| NO811943L (no) | Fremgangsmaate til fremstilling av encelleprotein med lavt nukleinsyreinnhold | |
| US4466988A (en) | Edible protein containing substances | |
| Frengova et al. | Carotenoid production by lactoso-negative yeasts co-cultivated with lactic acid bacteria in whey ultrafiltrate | |
| US6022537A (en) | Bacterial strains of the genus Bacillus, closely phenotypically related to the genus Lactobacillus, culture method and use | |
| Yoshida et al. | Production and application of maltose phosphorylase and trehalose phosphorylase by a strain of Plesiomonas | |
| US5702943A (en) | Process for preparing a biomass on a cereal medium, use of the products so prepared and panification ferment | |
| US4166004A (en) | Process for the preparation of single cell protein using Methylmonas clara ATCC 31226 | |
| US3689359A (en) | Method for producing citric acid | |
| US3674640A (en) | Cultivation of hydrocarbon-consuming yeasts | |
| Taillandier et al. | Influence of medium composition, pH and temperature on the growth and viability of Lactobacillus acidophilus | |
| US3622465A (en) | Protein from normal hydrocarbons | |
| CA1284464C (en) | D(-)-mandelate dehydrogenase produced microbiologically, a process for its production and application thereof | |
| US5071762A (en) | Enhancing the flavor of protein products derived from microorganisms |