NO801048L - Fremgangsmaate for halvsyntetisk fremstilling av humaninsulin - Google Patents

Fremgangsmaate for halvsyntetisk fremstilling av humaninsulin

Info

Publication number: NO801048L
Authority: NO; Norway
Prior art keywords: semi; procedure; human insulin; synthetic preparation; synthetic
Prior art date: 1979-04-13

Application number

NO801048A

Other languages

English (en)

Other versions

NO153061C (no

NO153061B (no

Inventor

Kazuyuki Morihara

Tatsushi Oka

Hiroshige Tsuzuki

Masami Soejima

Takeharu Masaki

Original Assignee

Shionogi & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-04-13

Filing date

1980-04-11

Publication date

1980-10-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26385768&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO801048(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1979-04-13 Priority claimed from JP4571079A external-priority patent/JPS55138393A/ja

1979-04-13 Priority claimed from JP4571179A external-priority patent/JPS55138391A/ja

1980-04-11 Application filed by Shionogi & Co filed Critical Shionogi & Co

1980-10-14 Publication of NO801048L publication Critical patent/NO801048L/no

1984-11-21 Priority to NO844636A priority Critical patent/NO163531C/no

1985-09-30 Publication of NO153061B publication Critical patent/NO153061B/no

1986-01-08 Publication of NO153061C publication Critical patent/NO153061C/no

Links

101000976075 Homo sapiens Insulin Proteins 0.000 title 1
PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO801048A 1979-04-13 1980-04-11 Fremgangsmaate for fremstilling av et b30-threonininsulin NO153061C (no)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
NO844636A NO163531C (no)	1979-04-13	1984-11-21	Beskyttet b30-thr(r1)(r2)-insulin egnet for fremstilling av et b30-threonininsulin.

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP4571079A JPS55138393A (en)	1979-04-13	1979-04-13	Semisynthesis of insulin
JP4571179A JPS55138391A (en)	1979-04-13	1979-04-13	New synthetic method of peptide derivative

Publications (3)

Publication Number	Publication Date
NO801048L true NO801048L (no)	1980-10-14
NO153061B NO153061B (no)	1985-09-30
NO153061C NO153061C (no)	1986-01-08

Family

ID=26385768

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO801048A NO153061C (no)	1979-04-13	1980-04-11	Fremgangsmaate for fremstilling av et b30-threonininsulin

Country Status (4)

Country	Link
EP (1)	EP0017938B1 (no)
DE (1)	DE3064479D1 (no)
DK (1)	DK146482C (no)
NO (1)	NO153061C (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK147437A (en) *	1980-02-11	1900-01-01		Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DK319780A (da) *	1980-07-24	1982-01-25	Forenede Bryggerier As	Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3101382A1 (de) *	1981-01-17	1982-09-02	Hoechst Ag, 6000 Frankfurt	"verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"
DK353781A (da) *	1981-08-10	1983-02-11	Novo Industri As	Fremgangsmaade til fremstilling af insulinderivater
EP0085083B1 (en) *	1981-08-10	1985-01-23	Nordisk Insulinlaboratorium	Process for the enzymatic preparation of human insulin
AU551174B2 (en) *	1981-09-15	1986-04-17	Nordisk Insulinlaboratorium	Enzymatic preparation of human insulin or b-30 esters thereof
DK149824C (da) *	1982-01-22	1987-03-16	Carlsberg Biotechnology Ltd	Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyrer i insuliner
WO1983002772A1 (en) *	1982-02-08	1983-08-18	Robin Ewart Offord	An improved method for preparing human insulin from non-human insulin
DE3209184A1 (de) *	1982-03-13	1983-09-15	Hoechst Ag, 6230 Frankfurt	Verfahren zur umwandlung von praeproinsulinanaloga zu insulinen
NL8201650A (nl) *	1982-04-21	1983-11-16	Akzo Nv	Semisynthetische bereiding van humane insuline.
EP0092829B1 (en) *	1982-04-23	1990-11-07	Wako Pure Chemical Industries, Ltd.	Process for semi-synthesis of human insulin and alkaline protease for use therein
DK55183D0 (da) *	1983-02-09	1983-02-09	Nordisk Insulinlab	Fremgangsmade til fremstilling af human insulin
DE3326472A1 (de) *	1983-07-22	1985-02-14	Hoechst Ag, 6230 Frankfurt	Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3333640A1 (de) *	1983-09-17	1985-04-25	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK119785D0 (da) *	1985-03-15	1985-03-15	Nordisk Gentofte	Insulinpraeparat
EP0294851A3 (de) *	1987-06-12	1990-05-09	Berlin-Chemie Ag	Verfahren zur Herstellung von Humaninsulin und seinen Derivaten

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3276961A (en) *	1963-04-08	1966-10-04	Squibb & Sons Inc	Process for preparing human insulin
NL7110277A (no) *	1970-07-31	1972-02-02
GB1426061A (en) *	1972-12-28	1976-02-25	Ici Ltd	Polypeptides
CH602599A5 (en) *	1974-03-27	1978-07-31	Ciba Geigy Ag	Insulin prodn. using different cysteine protecting groups
US4116768A (en) *	1975-04-29	1978-09-26	(Zaidanhojin) Sagami Chemical Research Center	Process for producing a peptide
GB1465235A (en) *	1975-04-29	1977-02-23	Sagami Chem Res	Process for preparing peptides

1980
- 1980-04-11 EP EP80101966A patent/EP0017938B1/en not_active Expired
- 1980-04-11 DE DE8080101966T patent/DE3064479D1/de not_active Expired
- 1980-04-11 DK DK155680A patent/DK146482C/da not_active IP Right Cessation
- 1980-04-11 NO NO801048A patent/NO153061C/no unknown

Also Published As

Publication number	Publication date
DK146482C (da)	1986-10-06
DE3064479D1 (en)	1983-09-08
EP0017938B1 (en)	1983-08-03
NO153061C (no)	1986-01-08
NO153061B (no)	1985-09-30
EP0017938A1 (en)	1980-10-29
DK146482B (da)	1983-10-17
DK155680A (da)	1980-10-14

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