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NO792337L - Fremgangsmaate for fremstilling av pyrimidinforbindelser - Google Patents

Fremgangsmaate for fremstilling av pyrimidinforbindelser

Info

Publication number
NO792337L
NO792337L NO792337A NO792337A NO792337L NO 792337 L NO792337 L NO 792337L NO 792337 A NO792337 A NO 792337A NO 792337 A NO792337 A NO 792337A NO 792337 L NO792337 L NO 792337L
Authority
NO
Norway
Prior art keywords
pyrimidone
stated
pyridylmethyl
methyl
pyridyl
Prior art date
Application number
NO792337A
Other languages
English (en)
Norwegian (no)
Inventor
Charon Robin Ganellin
Robert John Ife
David Andrew Arlwydd Owen
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of NO792337L publication Critical patent/NO792337L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO792337A 1978-07-15 1979-07-13 Fremgangsmaate for fremstilling av pyrimidinforbindelser NO792337L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7829999 1978-07-15

Publications (1)

Publication Number Publication Date
NO792337L true NO792337L (no) 1980-01-16

Family

ID=10498456

Family Applications (1)

Application Number Title Priority Date Filing Date
NO792337A NO792337L (no) 1978-07-15 1979-07-13 Fremgangsmaate for fremstilling av pyrimidinforbindelser

Country Status (20)

Country Link
US (4) US4305945A (es)
EP (1) EP0007232A1 (es)
JP (1) JPS5515499A (es)
KR (1) KR830001247A (es)
AR (1) AR226420A1 (es)
AT (1) AT370728B (es)
AU (1) AU528878B2 (es)
CA (1) CA1114375A (es)
DD (1) DD144916A5 (es)
DK (1) DK293079A (es)
ES (1) ES482448A1 (es)
FI (1) FI792220A7 (es)
GR (1) GR69252B (es)
IL (1) IL57790A (es)
NO (1) NO792337L (es)
NZ (1) NZ191006A (es)
PH (1) PH15979A (es)
PL (1) PL217121A1 (es)
PT (1) PT69886A (es)
ZA (1) ZA793392B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN151188B (es) * 1978-02-13 1983-03-05 Smith Kline French Lab
IL57005A (en) * 1978-04-11 1983-11-30 Smith Kline French Lab Process for the preparation of 2-amino pyrimid-4-one derivatives and novel 2-nitroaminopyrimid-4-ones as intermediates therefor
PT69886A (en) * 1978-07-15 1979-08-01 Smith Kline French Lab Process for preparing isoureas and isothioureas
DK558181A (da) * 1981-01-30 1982-07-31 Smithkline Corp Fremgangsmaade til fremstilling af 3,5-diamino-1,2,4-triazoler
US4477663A (en) * 1981-02-06 1984-10-16 Smithkline Beckman Corporation Intermediates for preparing substituted pyrimidinones
US4620001A (en) * 1981-02-06 1986-10-28 Smithkline Beckman Corporation Chemical methods and intermediates for preparing substituted pyrimidinones
JPH0641454B2 (ja) * 1985-02-27 1994-06-01 日産化学工業株式会社 ピリダジノン誘導体
DE3532880A1 (de) * 1985-09-14 1987-03-26 Basf Ag 1,4-disubstituierte pyrazolderivate
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1223686A (en) 1967-02-24 1971-03-03 Ici Ltd Salts of pyrimidine derivatives and the use thereof as fungicides
US3980781A (en) * 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
US4145546A (en) * 1975-10-02 1979-03-20 Smith Kline & French Laboratories Limited 4-Pyrimidone compounds
US4218452A (en) * 1975-10-02 1980-08-19 Smith Kline & French Laboratories Limited Substituted 4-pyrimidone compounds, compositions and methods of use
GB1578219A (en) * 1975-12-01 1980-11-05 Smith Kline French Lab Isothioureas
MW5076A1 (en) * 1975-12-29 1978-02-08 Smith Kline French Lab Pharmacologicalle active compounds
US4154834A (en) * 1975-12-29 1979-05-15 Smith Kline & French Laboratories Limited Substituted isocytosines having histamine H2 -antagonist activity
IN151188B (es) * 1978-02-13 1983-03-05 Smith Kline French Lab
PT69886A (en) * 1978-07-15 1979-08-01 Smith Kline French Lab Process for preparing isoureas and isothioureas

Also Published As

Publication number Publication date
US4439435A (en) 1984-03-27
JPS5515499A (en) 1980-02-02
FI792220A7 (fi) 1981-01-01
GR69252B (es) 1982-05-11
ES482448A1 (es) 1980-04-01
NZ191006A (en) 1982-09-07
DK293079A (da) 1980-01-16
AU528878B2 (en) 1983-05-19
ATA492279A (de) 1982-09-15
CA1114375A (en) 1981-12-15
AR226420A1 (es) 1982-07-15
ZA793392B (en) 1980-08-27
AT370728B (de) 1983-04-25
US4558128A (en) 1985-12-10
IL57790A (en) 1984-01-31
US4639519A (en) 1987-01-27
US4305945A (en) 1981-12-15
AU4895479A (en) 1980-01-24
PH15979A (en) 1983-05-16
DD144916A5 (de) 1980-11-12
IL57790A0 (en) 1979-11-30
EP0007232A1 (en) 1980-01-23
PL217121A1 (es) 1980-06-16
PT69886A (en) 1979-08-01
KR830001247A (ko) 1983-04-29

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