NO332405B1 - Compound of 5-substituted quinoline and isoquinoline derivatives, process for their preparation, their use in the preparation of pharmaceutical agents for the treatment of inflammatory disease and pharmaceutical composition comprising the compound. - Google Patents

Compound of 5-substituted quinoline and isoquinoline derivatives, process for their preparation, their use in the preparation of pharmaceutical agents for the treatment of inflammatory disease and pharmaceutical composition comprising the compound.

Info

Publication number: NO332405B1
Authority: NO; Norway
Prior art keywords: compound; preparation; treatment; inflammatory disease; pharmaceutical composition
Prior art date: 2004-11-12

Application number

NO20072963A

Other languages

Norwegian (no)

Other versions

NO20072963L (en

Inventor

Werner Skuballa

Orlin Petrov

Heike Schacke

Matthias Schneider

Hartmut Rehwinkel

Norbert Schmees

Stefan Jaroch

Jan Huebner

Christian Dinter

Original Assignee

Bayer Pharma AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-12

Filing date

2007-06-11

Publication date

2012-09-10

2005-04-26 Priority claimed from DE102005020331A external-priority patent/DE102005020331A1/en

2007-06-11 Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG

2007-08-03 Publication of NO20072963L publication Critical patent/NO20072963L/en

2012-09-10 Publication of NO332405B1 publication Critical patent/NO332405B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Hematology (AREA)
Physical Education & Sports Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Ophthalmology & Optometry (AREA)
Gastroenterology & Hepatology (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20072963A 2004-11-12 2007-06-11 Compound of 5-substituted quinoline and isoquinoline derivatives, process for their preparation, their use in the preparation of pharmaceutical agents for the treatment of inflammatory disease and pharmaceutical composition comprising the compound. NO332405B1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE102004055633A DE102004055633A1 (en)	2004-11-12	2004-11-12	New 5-substituted quinoline and isoquinoline derivatives are glucocorticoid receptor binders useful for treating inflammatory diseases e.g. alveolitis, Sjogren's syndrome, atopic dermatitis, acute lymphatic leukemia, rhinitis and emesis
DE102005020331A DE102005020331A1 (en)	2005-04-26	2005-04-26	New 5-substituted quinoline and isoquinoline derivatives are glucocorticoid receptor binders useful for treating inflammatory diseases e.g. alveolitis, Sjogren's syndrome, atopic dermatitis, acute lymphatic leukemia, rhinitis and emesis
PCT/EP2005/012531 WO2006050998A1 (en)	2004-11-12	2005-11-11	5-substituted quinoline and isoquinoline derivatives, a method for the production thereof and their use as antiphlogistics

Publications (2)

Publication Number	Publication Date
NO20072963L NO20072963L (en)	2007-08-03
NO332405B1 true NO332405B1 (en)	2012-09-10

Family

ID=35613753

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20072963A NO332405B1 (en)	2004-11-12	2007-06-11	Compound of 5-substituted quinoline and isoquinoline derivatives, process for their preparation, their use in the preparation of pharmaceutical agents for the treatment of inflammatory disease and pharmaceutical composition comprising the compound.

Country Status (30)

Country	Link
EP (1)	EP1844039B1 (en)
JP (1)	JP4460608B2 (en)
KR (1)	KR101168462B1 (en)
CN (1)	CN101124220B (en)
AR (1)	AR051767A1 (en)
AU (1)	AU2005303926B2 (en)
BR (1)	BRPI0517797A (en)
CA (1)	CA2586689C (en)
CY (1)	CY1110520T1 (en)
DE (2)	DE102004055633A1 (en)
DK (1)	DK1844039T3 (en)
EA (1)	EA013076B1 (en)
ES (1)	ES2329599T3 (en)
GT (1)	GT200500330A (en)
HR (1)	HRP20090509T1 (en)
IL (1)	IL182933A (en)
ME (2)	MEP13608A (en)
MX (1)	MX2007005736A (en)
MY (1)	MY141780A (en)
NO (1)	NO332405B1 (en)
NZ (1)	NZ555064A (en)
PA (1)	PA8652701A1 (en)
PE (1)	PE20061052A1 (en)
PL (1)	PL1844039T3 (en)
PT (1)	PT1844039E (en)
RS (2)	RS20070205A (en)
SI (1)	SI1844039T1 (en)
TW (1)	TWI311559B (en)
UY (1)	UY29213A1 (en)
WO (1)	WO2006050998A1 (en)

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US7297700B2 (en)	2005-03-24	2007-11-20	Renovis, Inc.	Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
TWI464148B (en)	2006-03-16	2014-12-11	Evotec Us Inc	Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
CN101484187B (en) *	2006-07-07	2012-12-26	博士伦公司	Compositions for the treatment of dry eye comprising a dissociated glucocorticoid receptor agonist and an immunosuppressant
SI2051710T1 (en) *	2006-08-07	2012-02-29	Bausch & Lomb	Compositions and methods for treating, reducing, ameliorating, or alleviating posterior-segment ophthalmic diseases
KR20090040369A (en) *	2006-08-07	2009-04-23	보오슈 앤드 롬 인코포레이팃드	Treatment of infectious diseases and their sequelae using a combination of dissociated glucocorticoid receptor agonists and anti-infective agents
PT2056799E (en) *	2006-08-31	2013-11-06	Bausch & Lomb	Compositions and methods for treating or preventing glaucoma or progression thereof
US20110104159A1 (en) *	2006-09-11	2011-05-05	Rohrs Brian R	Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy
US20110105559A1 (en) *	2006-09-11	2011-05-05	Rohrs Brian R	Compositions and Methods for Treating, Controlling, Reducing, Ameliorating, or Preventing Allergy
PL2061444T3 (en) *	2006-09-11	2011-09-30	Bausch & Lomb	Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy
JP2010509347A (en) *	2006-11-09	2010-03-25	ボーシュアンドロームインコーポレイティド	Selective synthesis of stereoisomers of certain substituted alcohols.
EP1982976A1 (en) *	2007-04-18	2008-10-22	Intendis GmbH	Process for the manufacture of non-steroidal anti-inflammatory agents and intermediates thereof
JP5725539B2 (en) *	2007-04-18	2015-05-27	インテンディスゲゼルシャフトミットベシュレンクテルハフツング	Non-steroidal anti-inflammatory agent and method for producing the same
EP2016935A1 (en) *	2007-07-09	2009-01-21	Intendis GmbH	Pharmaceutical composition for topical application of poorly soluble compounds
US20090042936A1 (en) *	2007-08-10	2009-02-12	Ward Keith W	Compositions and Methods for Treating or Controlling Anterior-Segment Inflammation
US20090087443A1 (en) *	2007-09-27	2009-04-02	Bartels Stephen P	Pharmacological Adjunctive Treatment Associated with Glaucoma Filtration Surgery
BRPI0818483A2 (en) *	2007-11-01	2015-04-14	Bausch & Lomb	Method for preparing a pharmaceutical composition, pharmaceutical composition, and use thereof.
US20110077270A1 (en) *	2009-04-21	2011-03-31	Pfeffer Bruce A	Compositions and Methods for Treating Ocular Inflammation with Lower Risk of Increased Intraocular Pressure
CN101983961B (en) *	2010-11-24	2012-05-09	浙江启明生化科技有限公司	Preparation method of 5-amino-2-methylquinoline
US20120316199A1 (en)	2011-06-07	2012-12-13	Ward Keith W	Compositions and methods for treating, controlling, reducing, or ameliorating inflammatory pain
WO2017137375A1 (en)	2016-02-12	2017-08-17	Bayer Animal Health Gmbh	Mapracorat for use in the treatment of canine dermatitis
CN111732493B (en) *	2017-01-16	2023-01-24	宜昌尚诺德生物医药科技有限公司	Synthesis process of arylamine compound
WO2020152193A1 (en)	2019-01-22	2020-07-30	Akribes Biomedical Gmbh	Selective glucocorticoid receptor modifiers for treating impaired skin wound healing

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE9017900U1 (en) *	1990-12-22	1993-01-28	Boehringer Ingelheim Kg, 55218 Ingelheim	3,4-Dihydro-1-benzyl-6,7-dimethoxy-α-[di-2-(2,3,4-trimethoxyphenyl)ethyl] aminocarbonyl-isoquinoline
NO306992B1 (en) *	1993-01-28	2000-01-24	Takeda Chemical Industries Ltd	Quinoline derivatives, pharmaceutical preparations containing the compounds and the use of the compounds
RU2127271C1 (en) *	1997-03-13	1999-03-10	Пермская государственная фармацевтическая академия	2-chloro-5,6,7,8-tetrahydroquinoline-4-carboxylic acid 5-nitrofurfurylidene hydrazide eliciting an antibacterial activity
UA73492C2 (en) *	1999-01-19	2005-08-15		Aromatic heterocyclic compounds as antiinflammatory agents
DE10215316C1 (en) *	2002-04-02	2003-12-18	Schering Ag	Quinoline and isoquinoline derivatives, a pharmaceutical agent and their use as anti-inflammatory agents
RU2005124558A (en) *	2003-01-03	2006-04-10	Берингер Ингельхайм Фармасьютиклз, Инк. (Us)	1-PROPANOL AND 1-PROPYLAMINE DERIVATIVES AND THEIR APPLICATION AS Glucocorticoid Ligands
US20040224992A1 (en) *	2003-02-27	2004-11-11	Boehringer Ingelheim Pharmaceuticals, Inc.	Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US7179919B2 (en) *	2004-03-18	2007-02-20	Boehringer Ingelheim Pharmaceuticals, Inc.	Stereoselective synthesis of certain trifluoromethyl-substituted alcohols

2004
- 2004-11-12 DE DE102004055633A patent/DE102004055633A1/en not_active Ceased
2005
- 2005-11-11 TW TW094139706A patent/TWI311559B/en not_active IP Right Cessation
- 2005-11-11 RS RSP-2007/0205A patent/RS20070205A/en unknown
- 2005-11-11 NZ NZ555064A patent/NZ555064A/en not_active IP Right Cessation
- 2005-11-11 WO PCT/EP2005/012531 patent/WO2006050998A1/en not_active Ceased
- 2005-11-11 CA CA2586689A patent/CA2586689C/en not_active Expired - Fee Related
- 2005-11-11 ES ES05808294T patent/ES2329599T3/en not_active Expired - Lifetime
- 2005-11-11 JP JP2007540615A patent/JP4460608B2/en not_active Expired - Fee Related
- 2005-11-11 MX MX2007005736A patent/MX2007005736A/en active IP Right Grant
- 2005-11-11 EA EA200700982A patent/EA013076B1/en not_active IP Right Cessation
- 2005-11-11 HR HR20090509T patent/HRP20090509T1/en unknown
- 2005-11-11 DK DK05808294T patent/DK1844039T3/en active
- 2005-11-11 DE DE502005007725T patent/DE502005007725D1/en not_active Expired - Lifetime
- 2005-11-11 AU AU2005303926A patent/AU2005303926B2/en not_active Ceased
- 2005-11-11 ME MEP-136/08A patent/MEP13608A/en unknown
- 2005-11-11 EP EP05808294A patent/EP1844039B1/en not_active Expired - Lifetime
- 2005-11-11 PL PL05808294T patent/PL1844039T3/en unknown
- 2005-11-11 KR KR1020077010785A patent/KR101168462B1/en not_active Expired - Fee Related
- 2005-11-11 RS RSP-2009/0367A patent/RS51161B/en unknown
- 2005-11-11 PT PT05808294T patent/PT1844039E/en unknown
- 2005-11-11 ME MEP-2008-136A patent/ME00155B/en unknown
- 2005-11-11 MY MYPI20055308A patent/MY141780A/en unknown
- 2005-11-11 BR BRPI0517797-9A patent/BRPI0517797A/en not_active IP Right Cessation
- 2005-11-11 SI SI200530792T patent/SI1844039T1/en unknown
- 2005-11-11 CN CN2005800464522A patent/CN101124220B/en not_active Expired - Fee Related
- 2005-11-11 GT GT200500330A patent/GT200500330A/en unknown
- 2005-11-14 AR ARP050104767A patent/AR051767A1/en not_active Application Discontinuation
- 2005-11-14 UY UY29213A patent/UY29213A1/en not_active Application Discontinuation
- 2005-11-14 PE PE2005001324A patent/PE20061052A1/en not_active Application Discontinuation
- 2005-11-14 PA PA20058652701A patent/PA8652701A1/en unknown
2007
- 2007-05-02 IL IL182933A patent/IL182933A/en not_active IP Right Cessation
- 2007-06-11 NO NO20072963A patent/NO332405B1/en not_active IP Right Cessation
2009
- 2009-10-15 CY CY20091101074T patent/CY1110520T1/en unknown

Also Published As

Publication number	Publication date
CN101124220A (en)	2008-02-13
UY29213A1 (en)	2006-05-31
SI1844039T1 (en)	2009-12-31
PA8652701A1 (en)	2006-07-03
NO20072963L (en)	2007-08-03
ME00155B (en)	2010-10-10
DE102004055633A1 (en)	2006-05-18
DK1844039T3 (en)	2009-11-09
GT200500330A (en)	2006-09-21
EA013076B1 (en)	2010-02-26
IL182933A (en)	2011-10-31
AR051767A1 (en)	2007-02-07
BRPI0517797A (en)	2008-10-21
RS51161B (en)	2010-10-31
AU2005303926A1 (en)	2006-05-18
TWI311559B (en)	2009-07-01
CA2586689A1 (en)	2006-05-18
PE20061052A1 (en)	2006-11-08
JP2008519803A (en)	2008-06-12
EA200700982A1 (en)	2007-10-26
ES2329599T3 (en)	2009-11-27
NZ555064A (en)	2009-09-25
TW200640913A (en)	2006-12-01
CN101124220B (en)	2012-04-25
RS20070205A (en)	2008-11-28
PT1844039E (en)	2009-10-19
KR20070084192A (en)	2007-08-24
PL1844039T3 (en)	2009-12-31
HK1112243A1 (en)	2008-08-29
WO2006050998A1 (en)	2006-05-18
MEP13608A (en)	2010-06-10
HRP20090509T1 (en)	2009-11-30
JP4460608B2 (en)	2010-05-12
KR101168462B1 (en)	2012-07-27
CA2586689C (en)	2012-04-17
DE502005007725D1 (en)	2009-08-27
MY141780A (en)	2010-06-30
IL182933A0 (en)	2007-09-20
EP1844039A1 (en)	2007-10-17
EP1844039B1 (en)	2009-07-15
AU2005303926B2 (en)	2011-05-19
MX2007005736A (en)	2007-09-07
CY1110520T1 (en)	2015-04-29

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