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NO326832B1 - Kombinasjon av benzosykloheptapyridinforbindelser og et antineoplastisk midel for fremstilling av et medikament for behandling av proliferative sykdommer. - Google Patents

Kombinasjon av benzosykloheptapyridinforbindelser og et antineoplastisk midel for fremstilling av et medikament for behandling av proliferative sykdommer. Download PDF

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Publication number
NO326832B1
NO326832B1 NO20003229A NO20003229A NO326832B1 NO 326832 B1 NO326832 B1 NO 326832B1 NO 20003229 A NO20003229 A NO 20003229A NO 20003229 A NO20003229 A NO 20003229A NO 326832 B1 NO326832 B1 NO 326832B1
Authority
NO
Norway
Prior art keywords
compound
paclitaxel
treatment
cells
cancer
Prior art date
Application number
NO20003229A
Other languages
English (en)
Norwegian (no)
Other versions
NO20003229D0 (no
NO20003229L (no
Inventor
Ronald James Doll
Viyyoor Moopil Girijavallabhan
Ashit K Ganguly
David L Cutler
Walter Robert Bishop
Joseph J Catino
Paul Kirschmeier
Ming Liu
Loretta L Nielsen
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27385940&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO326832(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO20003229D0 publication Critical patent/NO20003229D0/no
Publication of NO20003229L publication Critical patent/NO20003229L/no
Publication of NO326832B1 publication Critical patent/NO326832B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20003229A 1997-12-22 2000-06-21 Kombinasjon av benzosykloheptapyridinforbindelser og et antineoplastisk midel for fremstilling av et medikament for behandling av proliferative sykdommer. NO326832B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US99602797A 1997-12-22 1997-12-22
US14352998A 1998-08-28 1998-08-28
US18196998A 1998-10-29 1998-10-29
PCT/US1998/026224 WO1999032114A1 (en) 1997-12-22 1998-12-21 Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases

Publications (3)

Publication Number Publication Date
NO20003229D0 NO20003229D0 (no) 2000-06-21
NO20003229L NO20003229L (no) 2000-08-22
NO326832B1 true NO326832B1 (no) 2009-02-23

Family

ID=27385940

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003229A NO326832B1 (no) 1997-12-22 2000-06-21 Kombinasjon av benzosykloheptapyridinforbindelser og et antineoplastisk midel for fremstilling av et medikament for behandling av proliferative sykdommer.

Country Status (25)

Country Link
EP (1) EP1041985B1 (es)
JP (1) JP4502503B2 (es)
KR (1) KR100700907B1 (es)
CN (1) CN1129431C (es)
AR (1) AR017440A1 (es)
AT (1) ATE317697T1 (es)
AU (1) AU756762B2 (es)
BR (1) BR9814419A (es)
CA (1) CA2315693C (es)
CL (1) CL2007001889A1 (es)
CO (1) CO5080764A1 (es)
CZ (1) CZ298511B6 (es)
DE (1) DE69833509T2 (es)
DK (1) DK1041985T3 (es)
ES (1) ES2255196T3 (es)
HU (1) HUP0102473A3 (es)
IL (1) IL136462A0 (es)
MY (1) MY137303A (es)
NO (1) NO326832B1 (es)
NZ (1) NZ504928A (es)
PE (1) PE20000042A1 (es)
PT (1) PT1041985E (es)
SK (1) SK285584B6 (es)
TW (1) TW581763B (es)
WO (1) WO1999032114A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787327B1 (fr) * 1998-12-21 2003-01-17 Aventis Pharma Sa Compositions contenant des inhibiteurs de farnesyle transferase
WO2001034203A1 (fr) * 1999-11-09 2001-05-17 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Produit comprenant un inhibiteur de la transduction des signaux des proteines g heterotrimeriques en association avec un autre agent anti-cancereux pour une utilisation therapeutique dans le traitement du cancer
AU2292801A (en) * 1999-12-22 2001-07-03 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Compositions and methods for treatment of breast cancer
JP2003525236A (ja) * 2000-02-29 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ビンカアルカロイドとのファルネシルタンパク質トランスフェラーゼ阻害剤の組み合わせ剤
CA2397253A1 (en) * 2000-02-29 2001-09-07 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives
AU2001239275A1 (en) * 2000-02-29 2001-09-12 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives
US20030186925A1 (en) * 2000-02-29 2003-10-02 Palmer Peter Albert Farnesyl protein transferase inhibitor combinations with anti-tumor nucleoside derivatives
CA2397657A1 (en) * 2000-02-29 2001-09-07 Janssen Pharmaceutica Inc. Farnesyl protein transferase inhibitor combinations with platinum compounds
US20030078281A1 (en) * 2000-02-29 2003-04-24 Rybak Mary Ellen Margaret Farnesyl protein transferase inhibitor combinations with anti-tumor alkylating agents
TWI310684B (en) 2000-03-27 2009-06-11 Bristol Myers Squibb Co Synergistic pharmaceutical kits for treating cancer
AU2002236813A1 (en) * 2001-01-22 2002-07-30 Schering Corporation Treatment of malaria with farnesyl protein transferase inhibitors
ES2318000T3 (es) * 2001-02-15 2009-05-01 Janssen Pharmaceutica Nv Combinaciones de inhibidores de la farnesil-protein-transferasa con agentes antiestrogenos.
WO2003047697A2 (en) * 2001-11-30 2003-06-12 Schering Corporation Use of an farsenyl protein tranferase inhibitor in combination with other antineoplastic agents for the manufacture of a medicament against cancer
EP1453513A1 (en) * 2001-12-03 2004-09-08 Schering Corporation Use of fpt inhibitors and at least two antineoplastic agents in the treatment of cancer
WO2008022535A1 (fr) * 2006-08-09 2008-02-28 Tian Jin Tasly Group Co., Ltd. Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique
CN105198758A (zh) * 2015-09-22 2015-12-30 湖南大学 一种高纯度(z)-他莫昔酚的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
JPH06504772A (ja) * 1990-12-18 1994-06-02 ザ ウエルカム ファウンデーション リミテッド 抗癌剤の薬効を増強し抗多剤耐性を有する薬剤
JP2767176B2 (ja) * 1992-12-15 1998-06-18 大塚製薬株式会社 抗癌剤
US5637688A (en) * 1994-12-13 1997-06-10 Eli Lilly And Company Process for preparing 1-(2'-deoxy-2'-difluoro-d-ribofuranosyl)-4-aminopyrimidin-2-one hydrochloride
ATE302613T1 (de) * 1995-08-09 2005-09-15 Banyu Pharma Co Ltd Proteinfarnesyltransferase-inhibitoren in kombination mit hmgcoa-reduktase-inhibitoren zur behandlung von aids
EP1380581A1 (en) * 1995-12-22 2004-01-14 Schering Corporation Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative diseases
IL126179A (en) * 1996-03-12 2003-04-10 Pg Txl Co Lp Pharmaceutical compositions containing anti-tumor drug conjugates
CA2250143A1 (en) * 1996-04-03 1997-10-09 Jeffrey Bergman Inhibitors of farnesyl-protein transferase
JP2000508661A (ja) * 1996-04-15 2000-07-11 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 放射線および化学療法に対する細胞の感作
CA2251955A1 (en) * 1996-04-18 1997-10-23 Nancy E. Kohl A method of treating cancer
WO1997045412A1 (en) * 1996-05-30 1997-12-04 Merck & Co., Inc. A method of treating cancer
US6337992B1 (en) * 1997-01-29 2002-01-08 Philips Medical Systems Technologies Ltd. Predictive bolus tracking
KR100688409B1 (ko) * 1997-02-18 2007-03-02 캔지, 인크. 신생물에 대한 종양 억제 유전자 요법 및 화학 요법의 조합치료 방법

Also Published As

Publication number Publication date
ATE317697T1 (de) 2006-03-15
NO20003229D0 (no) 2000-06-21
EP1041985A1 (en) 2000-10-11
JP4502503B2 (ja) 2010-07-14
CZ20002236A3 (cs) 2001-04-11
WO1999032114A1 (en) 1999-07-01
DE69833509T2 (de) 2006-10-26
KR100700907B1 (ko) 2007-03-29
TW581763B (en) 2004-04-01
NO20003229L (no) 2000-08-22
MY137303A (en) 2009-01-30
AU1907299A (en) 1999-07-12
KR20010033452A (ko) 2001-04-25
SK285584B6 (sk) 2007-04-05
HUP0102473A3 (en) 2003-07-28
PE20000042A1 (es) 2000-02-17
AU756762B2 (en) 2003-01-23
DK1041985T3 (da) 2006-06-19
CN1284875A (zh) 2001-02-21
SK8982000A3 (en) 2001-04-09
AR017440A1 (es) 2001-09-05
CZ298511B6 (cs) 2007-10-24
CN1129431C (zh) 2003-12-03
EP1041985B1 (en) 2006-02-15
CO5080764A1 (es) 2001-09-25
ES2255196T3 (es) 2006-06-16
IL136462A0 (en) 2001-06-14
BR9814419A (pt) 2000-10-10
CA2315693A1 (en) 1999-07-01
NZ504928A (en) 2004-12-24
DE69833509D1 (de) 2006-04-20
HUP0102473A2 (hu) 2002-01-28
PT1041985E (pt) 2006-07-31
JP2001526224A (ja) 2001-12-18
CL2007001889A1 (es) 2008-01-11
CA2315693C (en) 2010-11-30

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