NO312720B1 - 1-fenylalkyl-1,2,3,6-tetrahydropyridiner, fremgangsmåte for fremstilling derav og farmasöytisk preparat - Google Patents

1-fenylalkyl-1,2,3,6-tetrahydropyridiner, fremgangsmåte for fremstilling derav og farmasöytisk preparat Download PDF

Info

Publication number: NO312720B1
Authority: NO; Norway
Prior art keywords: alkyl; ethyl; formula; compounds; salts
Prior art date: 1996-12-13

Application number

NO19992869A

Other languages

English (en)

Norwegian (no)

Other versions

NO992869L (no

NO992869D0 (no

Inventor

Marco Baroni

Rosanna Cardamone

Jacqueline Fournier

Umberto Guzzi

Original Assignee

Sanofi Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-13

Filing date

1999-06-11

Publication date

2002-06-24

1999-06-11 Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo

1999-06-11 Publication of NO992869L publication Critical patent/NO992869L/no

1999-06-11 Publication of NO992869D0 publication Critical patent/NO992869D0/no

2002-06-24 Publication of NO312720B1 publication Critical patent/NO312720B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)

NO19992869A 1996-12-13 1999-06-11 1-fenylalkyl-1,2,3,6-tetrahydropyridiner, fremgangsmåte for fremstilling derav og farmasöytisk preparat NO312720B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9615335A FR2757160B1 (fr)	1996-12-13	1996-12-13	1-phenylalkyl-1,2,3,6-tetrahydropyridines
PCT/FR1997/002286 WO1998025903A1 (fr)	1996-12-13	1997-12-12	1-phenylalkyl-1,2,3,6-tetrahydropyridines pour le traitement de la maladie d'alzheimer

Publications (3)

Publication Number	Publication Date
NO992869L NO992869L (no)	1999-06-11
NO992869D0 NO992869D0 (no)	1999-06-11
NO312720B1 true NO312720B1 (no)	2002-06-24

Family

ID=9498641

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19992869A NO312720B1 (no)	1996-12-13	1999-06-11	1-fenylalkyl-1,2,3,6-tetrahydropyridiner, fremgangsmåte for fremstilling derav og farmasöytisk preparat

Country Status (31)

Country	Link
US (1)	US6034090A (uk)
EP (1)	EP0950048B1 (uk)
JP (1)	JP3881384B2 (uk)
KR (1)	KR100560358B1 (uk)
CN (1)	CN1129579C (uk)
AT (1)	ATE202561T1 (uk)
AU (1)	AU730143B2 (uk)
BR (1)	BR9713916A (uk)
CA (1)	CA2275353C (uk)
CY (1)	CY2274B1 (uk)
CZ (1)	CZ289789B6 (uk)
DE (1)	DE69705429T2 (uk)
DK (1)	DK0950048T3 (uk)
EE (1)	EE03763B1 (uk)
ES (1)	ES2160977T3 (uk)
FR (1)	FR2757160B1 (uk)
GR (1)	GR3036643T3 (uk)
HU (1)	HU224347B1 (uk)
IL (1)	IL130003A (uk)
IS (1)	IS1969B (uk)
NO (1)	NO312720B1 (uk)
NZ (1)	NZ336033A (uk)
PL (1)	PL190789B1 (uk)
PT (1)	PT950048E (uk)
RS (1)	RS49807B (uk)
RU (1)	RU2189975C2 (uk)
SI (1)	SI0950048T1 (uk)
SK (1)	SK283331B6 (uk)
TR (1)	TR199901291T2 (uk)
UA (1)	UA52707C2 (uk)
WO (1)	WO1998025903A1 (uk)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2763847B1 (fr) *	1997-05-28	2003-06-06	Sanofi Sa	Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
UA81749C2 (uk) *	2001-10-04	2008-02-11	Х. Луннбек А/С	Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
FR2832405B1 (fr) *	2001-11-19	2004-12-10	Sanofi Synthelabo	Tetrahydropyridyl-alkyl-heterocycles azotes, procede pour leur preparation et compositions pharmaceutiques les contenant
RU2248203C2 (ru) *	2003-02-14	2005-03-20	Общество С Ограниченной Ответственностью "Научно-Производственное Объединение "Фарматрон"	Церебропротекторное и ноотропное лекарственное средство "ноотрил" в таблетках, покрытых оболочкой
KR101078505B1 (ko) *	2003-03-14	2011-10-31	오노 야꾸힝 고교 가부시키가이샤	질소 함유 복소환 유도체 및 이들을 유효 성분으로 하는약제
RU2376761C1 (ru) *	2008-08-06	2009-12-27	Закрытое акционерное общество "АЛЬФА-ТЭК"	Антисептическое и фунгицидное средство

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1321701A (en) *	1969-10-01	1973-06-27	Continental Pharma	Amino-alcohols their salts and process for prepairing the same
IE34545B1 (en) *	1969-10-01	1975-06-11	Continental Pharma	Amino-alcohols,their salts and process for preparing the same
FR2650505B1 (fr) *	1989-08-07	1994-06-03	Midy Spa	Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
FR2662355B1 (fr) *	1990-05-22	1994-11-10	Sanofi Sa	Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
HU211019B (en) *	1991-12-02	1995-09-28	Richter Gedeon Vegyeszet	Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds

1996
- 1996-12-13 FR FR9615335A patent/FR2757160B1/fr not_active Expired - Fee Related
1997
- 1997-12-12 AT AT97951323T patent/ATE202561T1/de not_active IP Right Cessation
- 1997-12-12 CA CA002275353A patent/CA2275353C/en not_active Expired - Fee Related
- 1997-12-12 SI SI9730187T patent/SI0950048T1/xx unknown
- 1997-12-12 PL PL334071A patent/PL190789B1/pl unknown
- 1997-12-12 CN CN97180581A patent/CN1129579C/zh not_active Expired - Fee Related
- 1997-12-12 PT PT97951323T patent/PT950048E/pt unknown
- 1997-12-12 DK DK97951323T patent/DK0950048T3/da active
- 1997-12-12 WO PCT/FR1997/002286 patent/WO1998025903A1/fr not_active Ceased
- 1997-12-12 DE DE69705429T patent/DE69705429T2/de not_active Expired - Fee Related
- 1997-12-12 JP JP52632098A patent/JP3881384B2/ja not_active Expired - Fee Related
- 1997-12-12 HU HU0001185A patent/HU224347B1/hu not_active IP Right Cessation
- 1997-12-12 SK SK786-99A patent/SK283331B6/sk unknown
- 1997-12-12 EE EEP199900237A patent/EE03763B1/xx not_active IP Right Cessation
- 1997-12-12 AU AU54893/98A patent/AU730143B2/en not_active Ceased
- 1997-12-12 ES ES97951323T patent/ES2160977T3/es not_active Expired - Lifetime
- 1997-12-12 TR TR1999/01291T patent/TR199901291T2/xx unknown
- 1997-12-12 CZ CZ19992113A patent/CZ289789B6/cs not_active IP Right Cessation
- 1997-12-12 US US09/331,006 patent/US6034090A/en not_active Expired - Fee Related
- 1997-12-12 RS YUP-243/99A patent/RS49807B/sr unknown
- 1997-12-12 BR BR9713916-5A patent/BR9713916A/pt not_active Application Discontinuation
- 1997-12-12 RU RU99115083/04A patent/RU2189975C2/ru not_active IP Right Cessation
- 1997-12-12 IL IL13000397A patent/IL130003A/en not_active IP Right Cessation
- 1997-12-12 NZ NZ336033A patent/NZ336033A/xx unknown
- 1997-12-12 UA UA99063286A patent/UA52707C2/uk unknown
- 1997-12-12 EP EP97951323A patent/EP0950048B1/fr not_active Expired - Lifetime
- 1997-12-12 KR KR1019997005203A patent/KR100560358B1/ko not_active Expired - Fee Related
1999
- 1999-06-10 IS IS5075A patent/IS1969B/is unknown
- 1999-06-11 NO NO19992869A patent/NO312720B1/no unknown
2001
- 2001-09-18 GR GR20010401501T patent/GR3036643T3/el not_active IP Right Cessation
2002
- 2002-05-15 CY CY0200027A patent/CY2274B1/xx unknown

Also Published As

Publication number	Publication date
GR3036643T3 (en)	2001-12-31
AU730143B2 (en)	2001-03-01
CA2275353A1 (en)	1998-06-18
EE9900237A (et)	1999-12-15
FR2757160B1 (fr)	1999-03-12
ES2160977T3 (es)	2001-11-16
HK1023997A1 (en)	2000-09-29
IL130003A0 (en)	2000-02-29
CA2275353C (en)	2007-05-22
SK78699A3 (en)	2000-01-18
DE69705429D1 (de)	2001-08-02
HU224347B1 (hu)	2005-08-29
KR100560358B1 (ko)	2006-03-14
TR199901291T2 (xx)	1999-10-21
YU24399A (sh)	2001-07-10
JP2001505902A (ja)	2001-05-08
KR20000069422A (ko)	2000-11-25
BR9713916A (pt)	2000-02-29
SI0950048T1 (en)	2001-10-31
HUP0001185A2 (hu)	2000-10-28
FR2757160A1 (fr)	1998-06-19
JP3881384B2 (ja)	2007-02-14
PT950048E (pt)	2001-12-28
ATE202561T1 (de)	2001-07-15
US6034090A (en)	2000-03-07
CZ289789B6 (cs)	2002-04-17
IS1969B (is)	2004-12-15
RU2189975C2 (ru)	2002-09-27
WO1998025903A1 (fr)	1998-06-18
EP0950048B1 (fr)	2001-06-27
EE03763B1 (et)	2002-06-17
DK0950048T3 (da)	2001-09-24
UA52707C2 (uk)	2003-01-15
PL334071A1 (en)	2000-01-31
AU5489398A (en)	1998-07-03
CN1129579C (zh)	2003-12-03
IL130003A (en)	2004-09-27
NO992869L (no)	1999-06-11
RS49807B (sr)	2008-08-07
CY2274B1 (en)	2003-07-04
PL190789B1 (pl)	2006-01-31
DE69705429T2 (de)	2002-05-16
IS5075A (is)	1999-06-10
NO992869D0 (no)	1999-06-11
CN1240427A (zh)	2000-01-05
EP0950048A1 (fr)	1999-10-20
HUP0001185A3 (en)	2002-10-28
SK283331B6 (sk)	2003-06-03
NZ336033A (en)	2000-12-22
CZ211399A3 (cs)	2000-09-13

Publication	Publication Date	Title
NO310144B1 (no)	2001-05-28	4-Aryl-1-fenylalkyl-1,2,3,6-tetrahydropyridiner med neurotropisk og neurobeskyttende aktivitet, fremgangsmåte forfremstilling derav og farmasöytisk sammensetning
JP3881384B2 (ja)	2007-02-14	アルツハイマー病処置用１−フェニルアルキル−１，２，３，６−テトラヒドロピリジン
US6124318A (en)	2000-09-26	Diphenylalkyl-tetrahydropyridines, process for their preparation, and pharmaceutical compositions containing them
US7151107B2 (en)	2006-12-19	Use of benzoylalkyl-1,2,3,6-tetrahydropyridines
MXPA99005108A (en)	2000-06-01	1-phenylalkyl-1,2,3,6-tetrahydropyridines for treating alzheimer's disease