[go: up one dir, main page]

NO20091912L - Metallkelater med en perfluorert PEG-gruppe, fremgangsmate for fremstilling derav, og anvendelse derav - Google Patents

Metallkelater med en perfluorert PEG-gruppe, fremgangsmate for fremstilling derav, og anvendelse derav

Info

Publication number
NO20091912L
NO20091912L NO20091912A NO20091912A NO20091912L NO 20091912 L NO20091912 L NO 20091912L NO 20091912 A NO20091912 A NO 20091912A NO 20091912 A NO20091912 A NO 20091912A NO 20091912 L NO20091912 L NO 20091912L
Authority
NO
Norway
Prior art keywords
preparation
metal chelates
peg group
perfluorinated peg
perfluorinated
Prior art date
Application number
NO20091912A
Other languages
English (en)
Inventor
Hanns-Joachim Weinmann
Johannes Platzek
Ludwig Zorn
Heiko Schirmer
Bernd Misselwitz
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of NO20091912L publication Critical patent/NO20091912L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/12Macromolecular compounds
    • A61K49/126Linear polymers, e.g. dextran, inulin, PEG
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

Oppfinnelsen vedrører gjenstandene som er kjennetegnet i kravene, nemlig metallkelater som har en perfluorert PEG-gruppe, en fremgangsmåte for fremstilling derav og anvendelse derav, en fremgangsmåte for fremstilling derav og anvendelse derav i NMR- og radiologi-diagnostikk, radiodiagnostikk og strålebehandling, og i MRT-lymfografi.
NO20091912A 2006-10-18 2009-05-15 Metallkelater med en perfluorert PEG-gruppe, fremgangsmate for fremstilling derav, og anvendelse derav NO20091912L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102006049821A DE102006049821A1 (de) 2006-10-18 2006-10-18 Metallchelate mit perfluoriertem PEG-Rest, Verfahren zu deren Herstellung, sowie deren Verwendung
US85296306P 2006-10-20 2006-10-20
US89007107P 2007-02-15 2007-02-15
PCT/EP2007/007284 WO2008046463A1 (de) 2006-10-18 2007-08-11 Metallchelate mit perfluoriertem peg-rest, verfahren zu deren herstellung sowie deren verwendung

Publications (1)

Publication Number Publication Date
NO20091912L true NO20091912L (no) 2009-07-17

Family

ID=38670854

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091912A NO20091912L (no) 2006-10-18 2009-05-15 Metallkelater med en perfluorert PEG-gruppe, fremgangsmate for fremstilling derav, og anvendelse derav

Country Status (21)

Country Link
US (1) US8263040B2 (no)
EP (1) EP2089362A1 (no)
JP (1) JP5475454B2 (no)
KR (1) KR101451446B1 (no)
CN (1) CN101687803B (no)
AU (1) AU2007312691A1 (no)
BR (1) BRPI0717466A2 (no)
CA (1) CA2666910C (no)
CO (1) CO6170342A2 (no)
CR (1) CR10727A (no)
CU (1) CU23837B1 (no)
DE (1) DE102006049821A1 (no)
GT (1) GT200900087A (no)
IL (1) IL198173A0 (no)
MX (1) MX2009004097A (no)
MY (1) MY148553A (no)
NO (1) NO20091912L (no)
NZ (1) NZ576249A (no)
RU (1) RU2470014C2 (no)
SG (1) SG177994A1 (no)
WO (1) WO2008046463A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2178862A1 (en) * 2007-08-13 2010-04-28 GE Healthcare AS Chelators, paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (mri)
US11529309B2 (en) * 2016-04-29 2022-12-20 University Of Houston System Compositions, methods and kits for treating a contact lens
EP3798281B1 (en) * 2018-05-16 2023-06-28 Guangzhou Ur Materials Technology Co., Ltd. Silane compound containg perfluoropolyether group, preparation method therefor, surface treatment agent and product thereof
CN113677737B (zh) * 2019-03-29 2024-06-07 大金工业株式会社 含氟代聚醚基的化合物

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588279A (en) * 1982-10-27 1986-05-13 Konishiroku Photo Industry Co., Ltd. Cleaning roller intermediate transfer member
US4586511A (en) * 1983-03-04 1986-05-06 Children's Hospital Medical Center Methods and compositions for detecting and imaging a gas in an animal by nuclear magnetic resonance
US4639364A (en) * 1984-11-14 1987-01-27 Mallinckrodt, Inc. Methods and compositions for enhancing magnetic resonance imaging
EP0292306A3 (en) 1987-05-20 1989-09-13 Nippon Shokubai Co., Ltd. Methylolaminotriazine condensates and method for production thereof
US4838274A (en) 1987-09-18 1989-06-13 Air Products And Chemicals, Inc. Perfluoro-crown ethers in fluorine magnetic resonance imaging
US5114703A (en) 1989-05-30 1992-05-19 Alliance Pharmaceutical Corp. Percutaneous lymphography using particulate fluorocarbon emulsions
DE4008179A1 (de) 1990-03-12 1991-09-19 Schering Ag Fluorbenzolsulfonamide
US5250283A (en) 1990-03-28 1993-10-05 Molecular Biosystems, Inc. Organic contrast agent analog and method of making same
US5318770A (en) 1991-10-25 1994-06-07 Mallinckrodt Medical, Inc. Trifluoromethyl analogs of X-ray contrast media for magnetic resonance imaging
DE4203254C2 (de) 1992-02-05 1996-05-02 Max Planck Gesellschaft Fluorhaltige Markierungsverbindung für NMR-Untersuchungen und deren Verwendung
US5482650A (en) 1992-04-28 1996-01-09 Minnesota Mining And Manufacturing Company Liquid crystal compounds having perfluoroether terminal portions
US5756688A (en) * 1992-10-14 1998-05-26 Sterling Winthrop Inc. MR imaging compositions and methods
US5362478A (en) * 1993-03-26 1994-11-08 Vivorx Pharmaceuticals, Inc. Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell
US5401493A (en) 1993-03-26 1995-03-28 Molecular Biosystems, Inc. Perfluoro-1H,-1H-neopentyl containing contrast agents and method to use same
DE4317588C2 (de) * 1993-05-24 1998-04-16 Schering Ag Fluorhaltige makrocyclische Metallkomplexe, Verfahren zu ihrer Herstellung, sowie ihre Verwendung
JPH0797340A (ja) 1993-06-03 1995-04-11 Terumo Corp Mri造影剤組成物
US5502094A (en) 1994-05-20 1996-03-26 Minnesota Mining And Manufacturing Company Physiologically acceptable emulsions containing perfluorocarbon ether hydrides and methods for use
US5702637A (en) * 1995-04-19 1997-12-30 Minnesota Mining And Manufacturing Company Liquid crystal compounds having a chiral fluorinated terminal portion
DE19603033A1 (de) * 1996-01-19 1997-07-24 Schering Ag Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
DE19729013A1 (de) * 1997-07-03 1999-02-04 Schering Ag Oligomere, perfluoralkylhaltige Verbindungen, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
DE19744004C1 (de) 1997-09-26 1999-07-22 Schering Ag Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging
US6495118B1 (en) * 1997-09-26 2002-12-17 Schering Aktiengesellschaft Lipophilic metal complexes for necrosis and infarction imaging
DE19744003B4 (de) 1997-09-26 2004-07-08 Schering Ag Kontrastmittel für das Infarkt- und Nekroseimaging
WO1999017809A2 (en) 1997-10-02 1999-04-15 Epix Medical, Inc. Contrast-enhanced diagnostic imaging method for monitoring interventional therapies
DE19914101C1 (de) 1999-03-22 2000-10-12 Schering Ag Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik
US6461587B1 (en) * 1999-03-22 2002-10-08 Schering Aktiengesellschaft Perfluoroalkylamides, their production and their use in diagnosis
DE19948651B4 (de) * 1999-09-29 2006-10-05 Schering Ag Para- und diamagnetische perfluorhaltige Verbindungen enthaltende galenische Formulierungen, deren Herstellung und Verwendung
US6939329B1 (en) * 1999-10-08 2005-09-06 Harvest Technologies Corporation Apparatus for holding and operating one or more syringes
US6676928B2 (en) * 2000-08-11 2004-01-13 Schering Aktiengesellschaft Perfluoroalkyl-containing complexes with polar radicals, process for their production and their use
US6641797B2 (en) * 2000-08-11 2003-11-04 Schering Aktiengesellschaft Perfluoroalkyl-containing complexes with sugar radicals, process for their production and their use
DE10066210B4 (de) * 2000-08-11 2008-02-28 Bayer Schering Pharma Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Plaques
DE10040858C2 (de) * 2000-08-11 2003-12-18 Schering Ag Perfluoralkylhaltige Komplexe mit polaren Resten, Verfahren zu deren Herstellung und ihre Verwendung
DE10040381C1 (de) * 2000-08-11 2002-06-06 Schering Ag Perfluoralkylhaltige Komplexe mit Zuckerresten, Verfahren zu deren Herstellung und ihre Verwendung
RU2206605C1 (ru) * 2002-03-18 2003-06-20 Здоров Юрий Павлович Противоизносная присадка к смазочным средам и топливу
WO2003086474A2 (en) * 2002-04-11 2003-10-23 Carbomer, Inc Fluorinated or paramagnetic alginate polymer, annexin paramagnetic conjugate, and their use as contrasting agent in mri
US7344704B2 (en) * 2002-07-10 2008-03-18 Schering Ag Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of intravascular thrombi
JP2004101881A (ja) * 2002-09-10 2004-04-02 Konica Minolta Holdings Inc ドライイメージング材料
JP5019883B2 (ja) * 2004-01-16 2012-09-05 カーネギー メロン ユニバーシティ 核磁気共鳴技術のための細胞標識
RU2296756C2 (ru) * 2005-05-17 2007-04-10 Федеральное унитарное государственное предприятие "Государственный научно-исследовательский институт биологического приборостроения" (ГосНИИ БП) Комплексообразующие дибензосодержащие пятичленные циклические соединения, содержащие два симметричных бета-дикарбонильных заместителя с фторированными радикалами

Also Published As

Publication number Publication date
RU2470014C2 (ru) 2012-12-20
MX2009004097A (es) 2009-07-10
JP2010506862A (ja) 2010-03-04
GT200900087A (es) 2010-04-19
RU2009118486A (ru) 2010-11-27
SG177994A1 (en) 2012-02-28
DE102006049821A1 (de) 2008-04-24
KR101451446B1 (ko) 2014-10-16
CU20090059A7 (es) 2011-03-21
KR20090082222A (ko) 2009-07-29
US20080159954A1 (en) 2008-07-03
CN101687803A (zh) 2010-03-31
WO2008046463A1 (de) 2008-04-24
HK1141526A1 (en) 2010-11-12
EP2089362A1 (de) 2009-08-19
JP5475454B2 (ja) 2014-04-16
CO6170342A2 (es) 2010-06-18
IL198173A0 (en) 2009-12-24
AU2007312691A1 (en) 2008-04-24
MY148553A (en) 2013-04-30
CR10727A (es) 2009-07-23
CA2666910A1 (en) 2008-04-24
US8263040B2 (en) 2012-09-11
CA2666910C (en) 2013-12-24
CN101687803B (zh) 2012-05-30
BRPI0717466A2 (pt) 2014-04-15
NZ576249A (en) 2012-03-30
CU23837B1 (es) 2012-10-15

Similar Documents

Publication Publication Date Title
CY1112511T1 (el) Κρυσταλλικη στερεα βαση ρασαγιλινης (rasagiline)
GB2476551B (en) Methods for treating superalloy articles, and related repair processes
GB0721285D0 (en) Method for tomographic inversion by matrix transformation
EP1944099A4 (en) Cooling method of steel plate
BRPI0717416A2 (pt) Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo
BR112013011406A2 (pt) aço para molas de alta resistência, método para produção de molas de alta resistência, e mola de alta resistência
IL187586A0 (en) Method for producing dihydroquinazolines
EP2392683A4 (en) HIGH TEMPERATURE GALVANIZED HOT-DIP STEEL SHEET AND METHOD OF MANUFACTURING THE SAME
ATE443038T1 (de) Verfahren zur herstellung von cinacalcet hydrochlorid
DE502007002301D1 (de) Verfahren zum Herstellen von Ventilgehäusen
MX2007001035A (es) Metodo para producir una composicion, la composicion y su uso.
EP2808417A4 (en) STEEL SHEET FOR HOT BOWLING, METHOD FOR MANUFACTURING THE SAME, AND PROCESS FOR PRODUCING HOT BOTTOM USING THE SAME
WO2009094717A3 (en) A method of inducing tolerance to an allergen
DE502006004266D1 (de) Luftsack, und verfahren zum herstellen eines gewebes für einen luftsack
AT10182U2 (de) Verfahren zur überwachung von leistungsprüfständen, sowie leistungsprüfstand
CY1115577T1 (el) Μεθοδος για την παρασκευη εναντιομερικως καθαρων αμινων
DK1994005T3 (da) Tetrahydronaphthalinderivater, fremgangsmåde til fremstilling heraf og anvendelse heraf som betændelseshæmmere
NO20091912L (no) Metallkelater med en perfluorert PEG-gruppe, fremgangsmate for fremstilling derav, og anvendelse derav
AT10460U3 (de) Prüfstands-konditioniersystem für ein arbeitsfluid, sowie vorrichtung zum betreiben eines derartigen prüfstands-konditioniersystems
MX362340B (es) Preparacion de intermediarios de agentes de contraste de rayos x.
EP2447269A4 (en) GADOLINIUM COMPLEX, PREPARATION METHOD THEREFOR, AND CONTRAST AGENT FOR NMR IMAGING CONTAINING THE SAME
DE112010002255A5 (de) Formeinsatz für eine formteilform, verfahren zum herstellen eines formteils und formteil
DE602005007157D1 (de) Verfahren für Arylamine Produktion
TW200740777A (en) Perfluoroalkyl-containing complexes, process for their production as well as their use
BRPI1006161A2 (pt) "aparelho não-adesivo, e, método para produzir hidrocarbonetos".

Legal Events

Date Code Title Description
RE Reestablishment of rights (par. 72 patents act)
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

FC2A Withdrawal, rejection or dismissal of laid open patent application