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NO20091793L - 2-pyridinkarboksamidderivat med GK-aktiverende virkning - Google Patents

2-pyridinkarboksamidderivat med GK-aktiverende virkning

Info

Publication number
NO20091793L
NO20091793L NO20091793A NO20091793A NO20091793L NO 20091793 L NO20091793 L NO 20091793L NO 20091793 A NO20091793 A NO 20091793A NO 20091793 A NO20091793 A NO 20091793A NO 20091793 L NO20091793 L NO 20091793L
Authority
NO
Norway
Prior art keywords
nitrogen
activating effect
lower alkyl
independently represent
alkyl group
Prior art date
Application number
NO20091793A
Other languages
English (en)
Inventor
Noriaki Hashimoto
Yufu Sagara
Masanori Asai
Teruyuki Nishimura
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of NO20091793L publication Critical patent/NO20091793L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

eller et farmasøytisk akseptabelt salt derav som har glukokinase-aktiverende aktivitet og som følgelig er anvendbar for behandling av diabetes eller fedme. (I) hvori R1 og R2 uavhengig av hverandre står for en lavere alkylgruppe, og Xi står for en gruppe representert ved formel (II-l) : hvori R11 og R12 uavhengig av hverandre står for et hydrogenatom eller en lavere alkylgruppe, eller R11 og R12 sammen med nitrogenatomet som R11 og R12 er bundet til, kan danne en nitrogenholdig, alifatisk ring med 4 til 7 medlemmer (hvori ett av karbonatomene som inngår i den nitrogenholdige, alifatiske
NO20091793A 2006-10-06 2009-05-05 2-pyridinkarboksamidderivat med GK-aktiverende virkning NO20091793L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006275824 2006-10-06
PCT/JP2007/070014 WO2008044777A1 (fr) 2006-10-06 2007-10-05 Dérivé de 2-pyridinecarboxamide ayant une activité d'activation de la gk

Publications (1)

Publication Number Publication Date
NO20091793L true NO20091793L (no) 2009-05-05

Family

ID=39282963

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091793A NO20091793L (no) 2006-10-06 2009-05-05 2-pyridinkarboksamidderivat med GK-aktiverende virkning

Country Status (22)

Country Link
US (1) US8338460B2 (no)
EP (1) EP2077266B1 (no)
JP (1) JP5292100B2 (no)
KR (1) KR20090060426A (no)
CN (1) CN101522673A (no)
AR (1) AR063028A1 (no)
AU (1) AU2007307560B2 (no)
BR (1) BRPI0716590A2 (no)
CA (1) CA2667068C (no)
CL (1) CL2007002890A1 (no)
CO (1) CO6180507A2 (no)
CR (1) CR10673A (no)
GT (1) GT200900065A (no)
IL (1) IL197714A0 (no)
MA (1) MA30813B1 (no)
MX (1) MX2009003073A (no)
NO (1) NO20091793L (no)
PE (1) PE20081195A1 (no)
RU (1) RU2009117209A (no)
SV (1) SV2009003196A (no)
TW (1) TW200831504A (no)
WO (1) WO2008044777A1 (no)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA82867C2 (en) * 2003-02-13 2008-05-26 Banyu Pharma Co Ltd 2-pyridinecarboxamide derivatives
AR063028A1 (es) 2006-10-06 2008-12-23 Banyu Pharma Co Ltd Derivados heterociclicos de piridin-2-carboxamida activadores de glucoquinasas, utiles para el tratamiento de diabetes y obesidad y composiciones farmaceuticas que los contienen.
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2009063821A1 (ja) 2007-11-12 2009-05-22 Banyu Pharmaceutical Co., Ltd. ヘテロアリールオキシキナゾリン誘導体
AU2009280579A1 (en) 2008-08-15 2010-02-18 Banyu Pharmaceutical Co.,Ltd. Acetyl pyrrolidinyl indole derivative
CA2734981A1 (en) * 2008-08-29 2010-03-04 Banyu Pharmaceutical Co., Ltd. Oxotetrahydrofuran-2-yl-benzimidazole derivative
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2931718B1 (en) * 2012-12-17 2019-01-16 Merck Sharp & Dohme Corp. Novel 2-pyridinecarboxamide derivatives, compositions containing such compounds, and methods of treatment
CN113045546A (zh) * 2021-03-25 2021-06-29 浙江天宇药业股份有限公司 一种吡咯替尼杂质、其制备方法及用途

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US3630200A (en) 1969-06-09 1971-12-28 Alza Corp Ocular insert
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
GB2277930A (en) 1993-05-11 1994-11-16 Shell Int Research Herbicidal picolinamide derivatives
US6022884A (en) 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
SE0102300D0 (sv) 2001-06-26 2001-06-26 Astrazeneca Ab Compounds
SE0102764D0 (sv) 2001-08-17 2001-08-17 Astrazeneca Ab Compounds
SE519859C2 (sv) 2001-08-17 2003-04-15 Novacast Ab Anordning för behandling av järnlegeringar i ett kärl
WO2003080585A1 (en) * 2002-03-26 2003-10-02 Banyu Pharmaceutical Co., Ltd. Novel aminobenzamide derivative
UA82867C2 (en) * 2003-02-13 2008-05-26 Banyu Pharma Co Ltd 2-pyridinecarboxamide derivatives
KR20050105488A (ko) * 2003-02-26 2005-11-04 반유 세이야꾸 가부시끼가이샤 헤테로아릴카바모일벤젠 유도체
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AR063028A1 (es) 2006-10-06 2008-12-23 Banyu Pharma Co Ltd Derivados heterociclicos de piridin-2-carboxamida activadores de glucoquinasas, utiles para el tratamiento de diabetes y obesidad y composiciones farmaceuticas que los contienen.

Also Published As

Publication number Publication date
AU2007307560B2 (en) 2012-10-04
CL2007002890A1 (es) 2008-01-18
SV2009003196A (es) 2009-07-28
PE20081195A1 (es) 2008-09-04
TW200831504A (en) 2008-08-01
EP2077266B1 (en) 2012-07-25
MA30813B1 (fr) 2009-10-01
RU2009117209A (ru) 2010-11-20
CA2667068A1 (en) 2008-04-17
IL197714A0 (en) 2009-12-24
CA2667068C (en) 2012-03-27
KR20090060426A (ko) 2009-06-12
CO6180507A2 (es) 2010-07-19
CR10673A (es) 2009-09-03
US20080090799A1 (en) 2008-04-17
BRPI0716590A2 (pt) 2012-12-25
WO2008044777A1 (fr) 2008-04-17
MX2009003073A (es) 2009-04-02
AR063028A1 (es) 2008-12-23
EP2077266A4 (en) 2010-07-07
AU2007307560A1 (en) 2008-04-17
JPWO2008044777A1 (ja) 2010-02-18
CN101522673A (zh) 2009-09-02
EP2077266A1 (en) 2009-07-08
US8338460B2 (en) 2012-12-25
GT200900065A (es) 2010-04-28
JP5292100B2 (ja) 2013-09-18

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