NO20090139L - Substituted phenyl acetic acids as DP-2 antagonists - Google Patents
Substituted phenyl acetic acids as DP-2 antagonistsInfo
- Publication number
- NO20090139L NO20090139L NO20090139A NO20090139A NO20090139L NO 20090139 L NO20090139 L NO 20090139L NO 20090139 A NO20090139 A NO 20090139A NO 20090139 A NO20090139 A NO 20090139A NO 20090139 L NO20090139 L NO 20090139L
- Authority
- NO
- Norway
- Prior art keywords
- antagonists
- substituted phenyl
- acetic acids
- phenyl acetic
- conditions
- Prior art date
Links
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical class OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 101150034985 Ptgdr2 gene Proteins 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
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- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
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- C07D217/08—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
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- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
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- Endocrinology (AREA)
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Abstract
Substituerte fenyleddiksyreforbindelser med formel (I), farmasøytiske sammensetninger, fremgangsmåter for deres fremstilling og fremgangsmåter er tilveiebrakt som er anvendelige ved behandling og hindring av forstyrrelser eller tilstander som responderer på DP-2-reseptormodulering, særlig inflammatoriske og immunrelaterte forstyrrelser og tilstander, slik som astma, allergisk rinitt og atopisk dermatitt.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81239906P | 2006-06-09 | 2006-06-09 | |
| PCT/US2007/070805 WO2007146838A2 (en) | 2006-06-09 | 2007-06-08 | Substituted phenyl acetic acids as dp-2 antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20090139L true NO20090139L (no) | 2009-03-05 |
Family
ID=38819983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20090139A NO20090139L (no) | 2006-06-09 | 2009-01-09 | Substituted phenyl acetic acids as DP-2 antagonists |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP2044017A2 (no) |
| JP (1) | JP2009539881A (no) |
| CN (1) | CN101490001A (no) |
| AU (1) | AU2007257841A1 (no) |
| BR (1) | BRPI0712332A2 (no) |
| CA (1) | CA2654927A1 (no) |
| EA (2) | EA200802417A1 (no) |
| MX (1) | MX2008015638A (no) |
| NO (1) | NO20090139L (no) |
| WO (1) | WO2007146838A2 (no) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007034620A1 (de) * | 2007-07-25 | 2009-01-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue B1-Antagonisten |
| EP2212277B1 (en) | 2007-10-19 | 2016-08-31 | Janssen Pharmaceutica, N.V. | Amine linked modulators of y-secretase |
| US8692017B2 (en) | 2007-10-19 | 2014-04-08 | Janssen Pharmaceutica, N.V. | Carbon linked modulators of gamma-secretase |
| BRPI0817433A2 (pt) * | 2007-10-19 | 2015-06-16 | Janssen Pharmaceutica Nv | Moduladores de gama-secretase piperidinila e piperazinila |
| SG177736A1 (en) * | 2009-07-31 | 2012-02-28 | Panmira Pharmaceuticals Llc | Dermal formulations of dp2 receptor antagonists |
| CN102812000A (zh) * | 2010-01-06 | 2012-12-05 | 潘米拉制药公司 | Dp2拮抗剂及其用途 |
| BR112013000254A2 (pt) | 2010-07-05 | 2016-05-24 | Actelion Pharmaceuticals Ltd | derivados heterocíclicos 1-fenil-substituídos e seu uso como moduladores do receptor de prostaglandina d2 |
| EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
| EP2487159A1 (en) * | 2011-02-11 | 2012-08-15 | MSD Oss B.V. | RorgammaT inhibitors |
| JP6277121B2 (ja) | 2011-03-22 | 2018-02-07 | アドヴィナス・セラピューティックス・リミテッド | 置換された縮合三環式化合物、その組成物および医学的応用 |
| ES2834093T3 (es) | 2011-07-21 | 2021-06-16 | Sumitomo Dainippon Pharma Oncology Inc | Inhibidores de proteína quinasa heterocíclicos |
| EP2573086A1 (en) * | 2011-09-26 | 2013-03-27 | AiCuris GmbH & Co. KG | N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate |
| EP2573085A1 (en) | 2011-09-26 | 2013-03-27 | AiCuris GmbH & Co. KG | N-[5-(aminosulfonyl)-4methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl] acetamide mesylate monohydrate having a specific particle size distribution range and a specific surface area range |
| EP2772480B2 (en) * | 2011-10-25 | 2020-12-09 | Shionogi & Co., Ltd. | Hiv replication inhibitor |
| US8691993B2 (en) * | 2011-12-12 | 2014-04-08 | Hoffmann-La Roche Inc. | Piperidinyl naphthylacetic acids |
| WO2013093842A1 (en) | 2011-12-21 | 2013-06-27 | Actelion Pharmaceuticals Ltd | Heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators |
| JO3407B1 (ar) | 2012-05-31 | 2019-10-20 | Eisai R&D Man Co Ltd | مركبات رباعي هيدرو بيرازولو بيريميدين |
| CN104428305A (zh) | 2012-07-05 | 2015-03-18 | 埃科特莱茵药品有限公司 | 1-苯基-取代的杂环衍生物及其作为前列腺素d2受体调节剂的用途 |
| JP6590226B2 (ja) * | 2016-05-11 | 2019-10-16 | 株式会社シード探索研究所 | オキサアジリジン化合物およびその製造方法 |
| KR102717600B1 (ko) | 2017-10-06 | 2024-10-15 | 포르마 세라퓨틱스 인크. | 유비퀴틴 특이적 펩티다제 30의 억제 |
| IL278291B2 (en) | 2018-05-17 | 2023-10-01 | Forma Therapeutics Inc | Fused bicyclic compounds useful as ubiquitin-specific peptidase 30 inhibitors |
| CA3110113A1 (en) | 2018-10-05 | 2020-04-09 | Forma Therapeutics, Inc. | Fused pyrrolines which act as ubiquitin-specific protease 30 (usp30) inhibitors |
| KR102904026B1 (ko) | 2019-02-12 | 2025-12-26 | 스미토모 파마 아메리카, 인크. | 헤테로시클릭 단백질 키나제 억제제를 포함하는 제제 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3991061A (en) * | 1975-07-16 | 1976-11-09 | G. D. Searle & Co. | Azanaphthaleneacetic acid derivatives |
| WO1993012086A1 (fr) * | 1991-12-11 | 1993-06-24 | Ss Pharmaceutical Co., Ltd. | Derive d'arylamide |
| ZA939516B (en) * | 1992-12-22 | 1994-06-06 | Smithkline Beecham Corp | Endothelin receptor antagonists |
| ES2401079T3 (es) * | 2002-12-20 | 2013-04-16 | Amgen Inc. | Moduladores del asma y de la inflamación alérgica |
| ES2399061T3 (es) * | 2005-09-30 | 2013-03-25 | Pulmagen Therapeutics (Asthma) Limited | Quinolinas y su uso terapéutico |
| GT200600457A (es) * | 2005-10-13 | 2007-04-27 | Aventis Pharma Inc | Sal de fosfato dihidrogeno como antagonistas del receptor de prostaglandina d2 |
-
2007
- 2007-06-08 EA EA200802417A patent/EA200802417A1/ru unknown
- 2007-06-08 JP JP2009514557A patent/JP2009539881A/ja not_active Withdrawn
- 2007-06-08 BR BRPI0712332-9A patent/BRPI0712332A2/pt not_active IP Right Cessation
- 2007-06-08 EA EA201200423A patent/EA201200423A1/ru unknown
- 2007-06-08 CA CA002654927A patent/CA2654927A1/en not_active Abandoned
- 2007-06-08 MX MX2008015638A patent/MX2008015638A/es not_active Application Discontinuation
- 2007-06-08 EP EP07812087A patent/EP2044017A2/en not_active Withdrawn
- 2007-06-08 AU AU2007257841A patent/AU2007257841A1/en not_active Abandoned
- 2007-06-08 CN CNA2007800262835A patent/CN101490001A/zh active Pending
- 2007-06-08 WO PCT/US2007/070805 patent/WO2007146838A2/en not_active Ceased
-
2009
- 2009-01-09 NO NO20090139A patent/NO20090139L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009539881A (ja) | 2009-11-19 |
| CN101490001A (zh) | 2009-07-22 |
| EP2044017A2 (en) | 2009-04-08 |
| WO2007146838A2 (en) | 2007-12-21 |
| BRPI0712332A2 (pt) | 2012-12-18 |
| EA200802417A1 (ru) | 2009-06-30 |
| WO2007146838A3 (en) | 2008-03-13 |
| CA2654927A1 (en) | 2007-12-21 |
| EA201200423A1 (ru) | 2012-08-30 |
| MX2008015638A (es) | 2009-01-09 |
| AU2007257841A1 (en) | 2007-12-21 |
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