NO20090591L - Metabolisme modulatorer samt behandling av lidelser relatert dertil - Google Patents
Metabolisme modulatorer samt behandling av lidelser relatert dertilInfo
- Publication number
- NO20090591L NO20090591L NO20090591A NO20090591A NO20090591L NO 20090591 L NO20090591 L NO 20090591L NO 20090591 A NO20090591 A NO 20090591A NO 20090591 A NO20090591 A NO 20090591A NO 20090591 L NO20090591 L NO 20090591L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- related disorders
- well
- metabolism modulators
- modulators
- Prior art date
Links
- 230000004060 metabolic process Effects 0.000 title 1
- -1 2-methyl-6- [1,2,4] triazol-1-yl-pyridin-3-ylamino Chemical group 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004153 glucose metabolism Effects 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81927806P | 2006-07-06 | 2006-07-06 | |
| PCT/US2007/015670 WO2008005569A2 (fr) | 2006-07-06 | 2007-07-05 | Modulateurs du métabolisme, et traitement de troubles au moyen de ces modulateurs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20090591L true NO20090591L (no) | 2009-02-06 |
Family
ID=38895258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20090591A NO20090591L (no) | 2006-07-06 | 2009-02-06 | Metabolisme modulatorer samt behandling av lidelser relatert dertil |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US20090286816A1 (fr) |
| EP (1) | EP2051976B1 (fr) |
| JP (1) | JP2009542699A (fr) |
| KR (1) | KR20090029781A (fr) |
| CN (1) | CN101484441A (fr) |
| AR (1) | AR061968A1 (fr) |
| AT (1) | ATE469145T1 (fr) |
| AU (1) | AU2007269571A1 (fr) |
| BR (1) | BRPI0713998A2 (fr) |
| CA (1) | CA2656623A1 (fr) |
| CL (1) | CL2007001971A1 (fr) |
| CO (1) | CO6160319A2 (fr) |
| CR (1) | CR10537A (fr) |
| DE (1) | DE602007006815D1 (fr) |
| DK (1) | DK2051976T3 (fr) |
| EA (1) | EA200970088A1 (fr) |
| EC (1) | ECSP099037A (fr) |
| ES (1) | ES2344965T3 (fr) |
| GT (1) | GT200800306A (fr) |
| IL (1) | IL195851A0 (fr) |
| MA (1) | MA30602B1 (fr) |
| MX (1) | MX2008016253A (fr) |
| NO (1) | NO20090591L (fr) |
| PE (1) | PE20080519A1 (fr) |
| SV (1) | SV2009003146A (fr) |
| TN (1) | TNSN08533A1 (fr) |
| TW (1) | TW200811147A (fr) |
| UY (1) | UY30467A1 (fr) |
| WO (1) | WO2008005569A2 (fr) |
| ZA (1) | ZA200900055B (fr) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| CN102558155A (zh) | 2003-01-14 | 2012-07-11 | 阿伦纳药品公司 | 作为代谢调节剂的芳基和杂芳基衍生物及其所涉及的疾病如糖尿病和高血糖症的预防和治疗 |
| US7501426B2 (en) | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
| KR101541791B1 (ko) | 2006-05-04 | 2015-08-04 | 베링거 인겔하임 인터내셔날 게엠베하 | 다형태 |
| EP1852108A1 (fr) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Compositions d'inhibiteurs de la DPP IV |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| EP2025674A1 (fr) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament |
| KR20100055536A (ko) | 2007-09-20 | 2010-05-26 | 아이알엠 엘엘씨 | Gpr119 활성의 조절제로서의 화합물 및 조성물 |
| PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| EP2108960A1 (fr) | 2008-04-07 | 2009-10-14 | Arena Pharmaceuticals, Inc. | Procédés d'utilisation d'un récepteur couplé à protéine G pour identifier les secrétagogues de peptide YY (PYY) et composés utiles dans le traitement des conditions modulées de secrétagogues BY (PYY) et composés utiles dans le traitement des conditions par PYY |
| UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
| KR20200118243A (ko) | 2008-08-06 | 2020-10-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
| BRPI0919288A2 (pt) | 2008-09-10 | 2015-12-15 | Boehring Ingelheim Internat Gmbh | teriapia de combinação para tratamento de diabetes e condições relacionadas. |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| KR20110103968A (ko) | 2008-12-23 | 2011-09-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 유기 화합물의 염 형태 |
| TW201036975A (en) | 2009-01-07 | 2010-10-16 | Boehringer Ingelheim Int | Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy |
| WO2010095663A1 (fr) | 2009-02-18 | 2010-08-26 | 武田薬品工業株式会社 | Composé à noyau hétérocyclique fusionné |
| US20100298362A1 (en) * | 2009-05-20 | 2010-11-25 | Xun Li | Process for the preparation of 4-[6-(6-methanesulfonyl-2-methyl-pyridin-3-ylamino)-5-methoxy-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester |
| WO2010149685A1 (fr) | 2009-06-24 | 2010-12-29 | Boehringer Ingelheim International Gmbh | Nouveaux composés, composition pharmaceutique et procédés s'y rapportant |
| EA201200046A1 (ru) | 2009-06-24 | 2012-08-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Новые соединения, фармацевтическая композиция и связанные с ними способы |
| KR20240090632A (ko) | 2009-11-27 | 2024-06-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 리나글립틴과 같은 dpp-iv 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료 |
| EP4148045A1 (fr) | 2010-01-27 | 2023-03-15 | Arena Pharmaceuticals, Inc. | Composés intermédiaires pour la préparation de l'acide (r)-2-(7-(4-cyclopentyl-3-(trifluorométhyl)benzyloxy)-1,2,3,4-tétrahydrocyclopenta[b]indol-3-yl) acétique et de ses sels |
| WO2011107494A1 (fr) | 2010-03-03 | 2011-09-09 | Sanofi | Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation |
| WO2011113947A1 (fr) | 2010-03-18 | 2011-09-22 | Boehringer Ingelheim International Gmbh | Combinaisons d'agonistes de gpr119 et d'inhibiteurs de dpp-iv, linagliptine, pour le traitement du diabète et d'états apparentés |
| ES2935300T3 (es) | 2010-05-05 | 2023-03-03 | Boehringer Ingelheim Int | Combiterapia |
| EP2582709B1 (fr) | 2010-06-18 | 2018-01-24 | Sanofi | Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| MX2012014247A (es) | 2010-06-24 | 2013-01-18 | Boehringer Ingelheim Int | Terapia para la diabetes. |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| WO2012025811A1 (fr) | 2010-08-23 | 2012-03-01 | Lupin Limited | Composés indolylpyrimidines en tant que modulateurs de gpr119 |
| EA201390421A1 (ru) | 2010-09-22 | 2013-09-30 | Арена Фармасьютикалз, Инк. | Модуляторы рецептора gpr119 и лечение связанных с ним нарушений |
| US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
| AU2011333472A1 (en) | 2010-11-26 | 2013-06-06 | Lupin Limited | Bicyclic GPR119 modulators |
| CN103958495B (zh) | 2011-06-09 | 2018-06-22 | 理森制药股份公司 | 作为gpr-119的调节剂的化合物 |
| ES2934843T3 (es) | 2011-07-15 | 2023-02-27 | Boehringer Ingelheim Int | Derivado de quinazolina dimérico sustituido, su preparación y su uso en composiciones farmacéuticas para el tratamiento de la diabetes de tipo I y II |
| WO2013037390A1 (fr) | 2011-09-12 | 2013-03-21 | Sanofi | Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
| EP2760862B1 (fr) | 2011-09-27 | 2015-10-21 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase |
| US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| US20130303462A1 (en) | 2012-05-14 | 2013-11-14 | Boehringer Ingelheim International Gmbh | Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome |
| EP4151218A1 (fr) | 2012-05-14 | 2023-03-22 | Boehringer Ingelheim International GmbH | Linagliptine, dérivé de xanthine en tant qu'inhibiteur de dpp-4, destinée à être utilisée dans le traitement de sirs et/ou de sepsis |
| WO2013174767A1 (fr) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | Dérivé de xanthine en tant qu'inhibiteur de la dpp-4 à utiliser dans la modification de l'apport alimentaire et dans la régulation des préférences alimentaires |
| US9771351B2 (en) | 2013-07-29 | 2017-09-26 | Kyowa Hakko Kirin Co., Ltd. | Wnt signaling inhibitor |
| EP3110449B1 (fr) | 2014-02-28 | 2023-06-28 | Boehringer Ingelheim International GmbH | Utilisation médicale d'un inhibiteur de dpp-4 |
| CN104003942A (zh) * | 2014-03-10 | 2014-08-27 | 常熟市南湖实业化工有限公司 | 避免串温现象产生的5-甲氧基-4,6-二氯嘧啶制备方法 |
| EP4445956A3 (fr) | 2015-01-06 | 2024-12-04 | Arena Pharmaceuticals, Inc. | Composé pour le traitement des affections associés à s1p1-récepteur |
| CN105111151B (zh) * | 2015-04-17 | 2018-09-28 | 成都理工大学 | 作为PPAR-γ调节剂的氨基嘧啶衍生物 |
| PL3310760T3 (pl) | 2015-06-22 | 2023-03-06 | Arena Pharmaceuticals, Inc. | Krystaliczna sól L-argininy kwasu (R)-2-(7-(4-cyklopentylo-3-(trifluorometylo)benzyloksy)- 1,2,3,4-tetrahydrocyklo-penta[b]indol-3-ilo)octowego do zastosowania w zaburzeniach związanych z receptorem S1P1 |
| WO2017211979A1 (fr) | 2016-06-10 | 2017-12-14 | Boehringer Ingelheim International Gmbh | Combinaisons de linagliptine et de metformine |
| CN110520124A (zh) | 2017-02-16 | 2019-11-29 | 艾尼纳制药公司 | 用于治疗原发性胆汁性胆管炎的化合物和方法 |
| CA3102136A1 (fr) | 2018-06-06 | 2019-12-12 | Arena Pharmaceuticals, Inc. | Methodes de traitement de troubles associes au recepteur s1p1<sb /> |
| CN108658871B (zh) * | 2018-06-19 | 2020-10-30 | 舞阳威森生物医药有限公司 | 周效磺胺中间体4,6-二氯-5-甲氧基嘧啶的制备方法 |
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| US6525064B1 (en) * | 2000-12-08 | 2003-02-25 | 3M Innovative Properties Company | Sulfonamido substituted imidazopyridines |
| CN102558155A (zh) * | 2003-01-14 | 2012-07-11 | 阿伦纳药品公司 | 作为代谢调节剂的芳基和杂芳基衍生物及其所涉及的疾病如糖尿病和高血糖症的预防和治疗 |
| ES2316964T3 (es) * | 2003-02-24 | 2009-04-16 | Arena Pharmaceuticals, Inc. | Fenil-y piridilpipereidinia-derivados como moduladores del metabolismo de la glucosa. |
| US7083933B1 (en) * | 2003-05-09 | 2006-08-01 | Prosidion Limited | Methods for identification of modulators of OSGPR116 activity |
| AR045047A1 (es) * | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
| AU2004257267B2 (en) * | 2003-07-14 | 2009-12-03 | Arena Pharmaceuticals,Inc | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| PT1756084E (pt) | 2004-06-04 | 2009-02-17 | Arena Pharm Inc | Composto seleccionado de compostos de fórmula (i) e seus sais, solvatos, hidratos e n-óxidos farmaceuticamente aceitáveis |
| MY148521A (en) * | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
-
2007
- 2007-07-02 TW TW096124029A patent/TW200811147A/zh unknown
- 2007-07-04 PE PE2007000859A patent/PE20080519A1/es not_active Application Discontinuation
- 2007-07-05 AT AT07810278T patent/ATE469145T1/de not_active IP Right Cessation
- 2007-07-05 US US12/307,549 patent/US20090286816A1/en not_active Abandoned
- 2007-07-05 AU AU2007269571A patent/AU2007269571A1/en not_active Withdrawn
- 2007-07-05 CA CA002656623A patent/CA2656623A1/fr not_active Abandoned
- 2007-07-05 WO PCT/US2007/015670 patent/WO2008005569A2/fr not_active Ceased
- 2007-07-05 ES ES07810278T patent/ES2344965T3/es active Active
- 2007-07-05 KR KR1020097000107A patent/KR20090029781A/ko not_active Withdrawn
- 2007-07-05 EA EA200970088A patent/EA200970088A1/ru unknown
- 2007-07-05 CL CL2007001971A patent/CL2007001971A1/es unknown
- 2007-07-05 CN CNA2007800250772A patent/CN101484441A/zh not_active Withdrawn
- 2007-07-05 JP JP2009518398A patent/JP2009542699A/ja not_active Withdrawn
- 2007-07-05 MX MX2008016253A patent/MX2008016253A/es active IP Right Grant
- 2007-07-05 EP EP07810278A patent/EP2051976B1/fr active Active
- 2007-07-05 BR BRPI0713998-5A patent/BRPI0713998A2/pt not_active IP Right Cessation
- 2007-07-05 DE DE602007006815T patent/DE602007006815D1/de active Active
- 2007-07-05 DK DK07810278.7T patent/DK2051976T3/da active
- 2007-07-06 AR ARP070103027A patent/AR061968A1/es unknown
- 2007-07-06 UY UY30467A patent/UY30467A1/es unknown
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2008
- 2008-01-05 ZA ZA200900055A patent/ZA200900055B/xx unknown
- 2008-12-10 IL IL195851A patent/IL195851A0/en unknown
- 2008-12-19 CR CR10537A patent/CR10537A/es not_active Application Discontinuation
- 2008-12-24 CO CO08136750A patent/CO6160319A2/es unknown
- 2008-12-25 TN TNP2008000533A patent/TNSN08533A1/en unknown
- 2008-12-29 GT GT200800306A patent/GT200800306A/es unknown
-
2009
- 2009-01-06 EC EC2009009037A patent/ECSP099037A/es unknown
- 2009-01-06 SV SV2009003146A patent/SV2009003146A/es unknown
- 2009-01-27 MA MA31591A patent/MA30602B1/fr unknown
- 2009-02-06 NO NO20090591A patent/NO20090591L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20090029781A (ko) | 2009-03-23 |
| CA2656623A1 (fr) | 2008-01-10 |
| HK1128921A1 (en) | 2009-11-13 |
| ES2344965T3 (es) | 2010-09-10 |
| MX2008016253A (es) | 2009-02-25 |
| EP2051976A2 (fr) | 2009-04-29 |
| CN101484441A (zh) | 2009-07-15 |
| WO2008005569A3 (fr) | 2008-04-10 |
| CL2007001971A1 (es) | 2008-01-25 |
| EA200970088A1 (ru) | 2009-06-30 |
| DK2051976T3 (da) | 2010-09-20 |
| TW200811147A (en) | 2008-03-01 |
| ECSP099037A (es) | 2009-02-27 |
| EP2051976B1 (fr) | 2010-05-26 |
| BRPI0713998A2 (pt) | 2012-11-20 |
| CO6160319A2 (es) | 2010-05-20 |
| AR061968A1 (es) | 2008-08-10 |
| PE20080519A1 (es) | 2008-05-16 |
| US20090286816A1 (en) | 2009-11-19 |
| ATE469145T1 (de) | 2010-06-15 |
| DE602007006815D1 (de) | 2010-07-08 |
| GT200800306A (es) | 2009-04-20 |
| UY30467A1 (es) | 2008-02-29 |
| AU2007269571A1 (en) | 2008-01-10 |
| ZA200900055B (en) | 2009-12-30 |
| MA30602B1 (fr) | 2009-07-01 |
| TNSN08533A1 (en) | 2010-04-14 |
| JP2009542699A (ja) | 2009-12-03 |
| CR10537A (es) | 2009-01-27 |
| WO2008005569A2 (fr) | 2008-01-10 |
| SV2009003146A (es) | 2009-11-04 |
| IL195851A0 (en) | 2009-09-01 |
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