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NO20084632L - Nye krystaller av 3-[5-[4-(cyclopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]-fenyl]propion syre - Google Patents

Nye krystaller av 3-[5-[4-(cyclopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]-fenyl]propion syre

Info

Publication number
NO20084632L
NO20084632L NO20084632A NO20084632A NO20084632L NO 20084632 L NO20084632 L NO 20084632L NO 20084632 A NO20084632 A NO 20084632A NO 20084632 A NO20084632 A NO 20084632A NO 20084632 L NO20084632 L NO 20084632L
Authority
NO
Norway
Prior art keywords
hydroxybenzoyl
cyclopentyloxy
hydroxy
propionic acid
benzisoxazol
Prior art date
Application number
NO20084632A
Other languages
English (en)
Inventor
Yukie Tada
Kenji Yonezawa
Hironori Kotsubo
Yasutaka Baba
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of NO20084632L publication Critical patent/NO20084632L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Krystallen av 3-{5-[4-(cyklopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]fenyl}propionsyre som har topper i posisjonene 14,0, 16,0, 23,3, 23,7 og 26,3° og krystallen av 3-{5-[4-(cyklopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]fenyl}propionsyre som har topper i posisjonene 14,6, 23,1, 24,7, 25,6 og 26,0° ved diffraksjonsvinkel 2? i et pulver røntgendiffraksjonsmønster, har et lite, spesifikt volum, lar seg vanskelig lade med elektrisitet, er lett håndterbare og er anvendelige som en aktiv farmasøytisk bestanddel i utmerkede antirevmatiske midler.
NO20084632A 2006-05-26 2008-11-04 Nye krystaller av 3-[5-[4-(cyclopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]-fenyl]propion syre NO20084632L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006146220 2006-05-26
PCT/JP2007/060670 WO2007138996A1 (ja) 2006-05-26 2007-05-25 ３－｛５－［４－（シクロペンチルオキシ）－２－ヒドロキシベンゾイル］－２－［（３－ヒドロキシ－１，２－ベンズイソオキサゾール－６－イル）メトキシ］フェニル｝プロピオン酸の新規な結晶

Publications (1)

Publication Number Publication Date
NO20084632L true NO20084632L (no) 2008-12-12

Family

ID=38778516

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084632A NO20084632L (no) 2006-05-26 2008-11-04 Nye krystaller av 3-[5-[4-(cyclopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]-fenyl]propion syre

Country Status (27)

Country Link
US (1) US7977492B2 (no)
EP (1) EP2022788B1 (no)
JP (1) JP5117381B2 (no)
KR (1) KR101389038B1 (no)
CN (1) CN101454298B (no)
AT (1) ATE479666T1 (no)
AU (1) AU2007268771B2 (no)
BR (1) BRPI0712909A2 (no)
CA (1) CA2652939C (no)
CY (1) CY1111398T1 (no)
DE (1) DE602007008882D1 (no)
DK (1) DK2022788T3 (no)
EC (1) ECSP089000A (no)
ES (1) ES2351065T3 (no)
HR (1) HRP20100544T1 (no)
IL (1) IL195416A (no)
MA (1) MA30510B1 (no)
MX (1) MX2008014906A (no)
NO (1) NO20084632L (no)
NZ (1) NZ573034A (no)
PL (1) PL2022788T3 (no)
PT (1) PT2022788E (no)
RS (1) RS51517B (no)
RU (1) RU2429233C2 (no)
SI (1) SI2022788T1 (no)
WO (1) WO2007138996A1 (no)
ZA (1) ZA200809922B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1988085B8 (en) * 2006-02-21 2015-01-28 Toyama Chemical Co., Ltd. Process for production of 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6-yl)methoxy]phenyl]propionate ester and intermediate for the process
CA2719290A1 (en) * 2008-03-27 2009-10-01 Toyama Chemical Co., Ltd. Use of benzophenone derivative or salt thereof and tnf.alpha. inhibitor in combination and pharmaceutical composition containing the derivative or salt thereof and the inhibitor
MX2010011666A (es) 2008-04-22 2010-12-06 Toyama Chemical Co Ltd Metodo para usar una combinacion de derivado de benzofenona o sal del mismo y un agente inmunosupresor, y una composicion farmaceutica que consta de estos compuestos.
CN103183647B (zh) * 2011-12-28 2017-06-09 天津市国际生物医药联合研究院有限公司 3‑{[2‑[3‑氧‑(1,2‑苯并异噻唑‑6‑基)甲氧基‑5‑(2‑羟基‑4‑环戊氧基苯甲酰基)]苯基}丙酸的制备方法
CN118255728B (zh) * 2024-01-25 2024-07-30 中国医学科学院阜外医院 化合物的盐型晶型用于治疗射血分数保留的心衰的用途
CN118252824B (zh) * 2024-01-25 2024-09-17 中国医学科学院阜外医院 化合物用于治疗射血分数保留的心衰的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042150A (en) 1960-01-26 1962-07-03 Lukawsky Michael Emergency brake and anti-skid device
CA1320490C (en) * 1987-01-12 1993-07-20 Darrel M. Gapinski Anti-inflammatory agents
EP0708094A4 (en) * 1993-07-06 1996-08-28 Yamanouchi Pharma Co Ltd NEW CRYSTAL OF A BENZODIAZEPINE DERIVATE
US7314888B1 (en) 1998-11-05 2008-01-01 Toyama Chemical Co., Ltd. Compounds and medicinal use thereof
JP4976617B2 (ja) 2000-03-17 2012-07-18 富山化学工業株式会社 新規なベンゾフェノン誘導体およびその塩
CN1602291B (zh) * 2001-11-16 2010-05-12 富山化学工业株式会社 新二苯甲酮衍生物或其盐

Also Published As

Publication number Publication date
CN101454298A (zh) 2009-06-10
SI2022788T1 (sl) 2011-01-31
IL195416A0 (en) 2009-08-03
CY1111398T1 (el) 2015-08-05
WO2007138996A1 (ja) 2007-12-06
RU2008151778A (ru) 2010-07-10
JP5117381B2 (ja) 2013-01-16
ES2351065T3 (es) 2011-01-31
ZA200809922B (en) 2010-02-24
AU2007268771B2 (en) 2011-12-01
AU2007268771A1 (en) 2007-12-06
EP2022788A1 (en) 2009-02-11
EP2022788B1 (en) 2010-09-01
DE602007008882D1 (de) 2010-10-14
ECSP089000A (es) 2009-02-27
CA2652939A1 (en) 2007-12-06
RS51517B (sr) 2011-06-30
PT2022788E (pt) 2010-10-04
CA2652939C (en) 2014-12-02
MX2008014906A (es) 2008-12-09
MA30510B1 (fr) 2009-06-01
IL195416A (en) 2012-07-31
KR101389038B1 (ko) 2014-04-28
US20090275757A1 (en) 2009-11-05
HRP20100544T1 (hr) 2010-11-30
US7977492B2 (en) 2011-07-12
JPWO2007138996A1 (ja) 2009-10-08
NZ573034A (en) 2010-08-27
PL2022788T3 (pl) 2011-03-31
BRPI0712909A2 (pt) 2012-10-02
DK2022788T3 (da) 2010-12-13
CN101454298B (zh) 2011-11-16
RU2429233C2 (ru) 2011-09-20
EP2022788A4 (en) 2009-06-24
ATE479666T1 (de) 2010-09-15
KR20090014194A (ko) 2009-02-06

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