NO20084542L - Farmasoytisk kombinasjon inneholdende 3-(3-dimetylamino-1-etyl-2-metyl-propyl)-fenol og paracetamol - Google Patents
Farmasoytisk kombinasjon inneholdende 3-(3-dimetylamino-1-etyl-2-metyl-propyl)-fenol og paracetamolInfo
- Publication number
- NO20084542L NO20084542L NO20084542A NO20084542A NO20084542L NO 20084542 L NO20084542 L NO 20084542L NO 20084542 A NO20084542 A NO 20084542A NO 20084542 A NO20084542 A NO 20084542A NO 20084542 L NO20084542 L NO 20084542L
- Authority
- NO
- Norway
- Prior art keywords
- paracetamol
- dimethylamino
- phenol
- propyl
- ethyl
- Prior art date
Links
- KWTWDQCKEHXFFR-UHFFFAOYSA-N 3-[1-(dimethylamino)-2-methylpentan-3-yl]phenol Chemical compound CN(C)CC(C)C(CC)C1=CC=CC(O)=C1 KWTWDQCKEHXFFR-UHFFFAOYSA-N 0.000 title abstract 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title abstract 2
- 229960005489 paracetamol Drugs 0.000 title abstract 2
- 208000002193 Pain Diseases 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- 208000005298 acute pain Diseases 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Det er beskrevet en kombinasjon omfattende som komponenter (a) forbindelsen 3-(3dimetylamino-1-etyl-2-metyl-propyl)-fenol og (b) paracetamol eller et derivat derav, et farmasøytisk preparat og en doseringsform omfattende nevnte kombinasjon så vel som en fremgangsmåte for behandling av smerte, for eksempel kronisk eller akutt smerte, kjennetegnet ved at komponenter (a) og (b) administreres samtidig eller trinnvis til et pattedyr, hvori komponent (a) kan administreres før eller komponent (b) og hvori komponentene (a) eller (b) administreres til pattedyret enten via samme eller forskjellig administrasjonsvei.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06008851 | 2006-04-28 | ||
| PCT/EP2007/003632 WO2007128413A1 (en) | 2006-04-28 | 2007-04-25 | Pharmaceutical combination comprising 3- ( 3-dimethylamino-1-ethyl-2-methyl-propyl) -phenol and paracetamol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20084542L true NO20084542L (no) | 2008-10-28 |
| NO341602B1 NO341602B1 (no) | 2017-12-11 |
Family
ID=37025148
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20084542A NO341602B1 (no) | 2006-04-28 | 2008-10-28 | Farmasøytisk kombinasjon omfattende 3-(3-dimetylamino-1-etyl-2-metyl-propyl)-fenol og paracetamol |
| NO20171831A NO343505B1 (no) | 2006-04-28 | 2017-11-17 | Farmasøytisk kombinasjon omfattende 3-(3-dimetylamino-1-etyl-2-metylpropyl)-fenyl og paracetamol |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20171831A NO343505B1 (no) | 2006-04-28 | 2017-11-17 | Farmasøytisk kombinasjon omfattende 3-(3-dimetylamino-1-etyl-2-metylpropyl)-fenyl og paracetamol |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP2012764B1 (no) |
| JP (2) | JP5496653B2 (no) |
| KR (1) | KR101396166B1 (no) |
| CN (1) | CN101431990B (no) |
| AT (1) | ATE494889T1 (no) |
| AU (1) | AU2007247481B2 (no) |
| BR (1) | BRPI0710682B8 (no) |
| CA (1) | CA2650423C (no) |
| CY (1) | CY1111369T1 (no) |
| DE (1) | DE602007011913D1 (no) |
| DK (1) | DK2012764T3 (no) |
| EC (2) | ECSP088793A (no) |
| ES (1) | ES2356093T3 (no) |
| HR (1) | HRP20110076T1 (no) |
| IL (1) | IL194883A (no) |
| MX (1) | MX2008013779A (no) |
| NO (2) | NO341602B1 (no) |
| NZ (1) | NZ571442A (no) |
| PL (1) | PL2012764T3 (no) |
| PT (1) | PT2012764E (no) |
| RU (1) | RU2442576C2 (no) |
| SI (1) | SI2012764T1 (no) |
| WO (1) | WO2007128413A1 (no) |
| ZA (1) | ZA200810124B (no) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007012165A1 (de) | 2007-03-12 | 2008-09-18 | Grünenthal GmbH | Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes |
| CN102908339A (zh) * | 2007-11-23 | 2013-02-06 | 格吕伦塔尔有限公司 | 他喷他多组合物 |
| RU2589692C2 (ru) | 2010-06-15 | 2016-07-10 | Грюненталь Гмбх | Фармацевтическая комбинация для лечения от боли |
| BR112013022495A2 (pt) | 2011-03-04 | 2016-12-06 | Gruenenthal Gmbh | formulação farmacêutica aquosa de tapentadol para administração oral |
| JP2014510067A (ja) * | 2011-03-04 | 2014-04-24 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | タペンタドールの非経口的投与 |
| PT3766489T (pt) | 2011-05-03 | 2022-04-07 | Gruenenthal Gmbh | Composição farmacêutica aquosa semissólida contendo tapentadol |
| US20130310435A1 (en) * | 2012-05-18 | 2013-11-21 | Gruenenthal Gmbh | Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol |
| US9855286B2 (en) | 2012-05-18 | 2018-01-02 | Gruenenthal Gmbh | Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component |
| US20130310385A1 (en) | 2012-05-18 | 2013-11-21 | Gruenenthal Gmbh | Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants |
| US9320729B2 (en) | 2012-05-18 | 2016-04-26 | Gruenenthal Gmbh | Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative |
| EP2808319A1 (en) | 2013-05-31 | 2014-12-03 | Arevipharma GmbH | 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex |
| PT3273953T (pt) | 2015-03-27 | 2019-04-01 | Gruenenthal Gmbh | Formulação estável para administração parentérica de tapentadol |
| EP3515412B1 (en) | 2016-09-23 | 2025-04-23 | Grünenthal GmbH | Stable formulation for parenteral administration of tapentadol |
| EP3585370A1 (en) | 2017-02-23 | 2020-01-01 | Grünenthal GmbH | Tapentadol as local anesthetic |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4426245A1 (de) * | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| PE20030527A1 (es) * | 2001-10-24 | 2003-07-26 | Gruenenthal Chemie | Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen |
| ATE465726T1 (de) * | 2002-11-22 | 2010-05-15 | Gruenenthal Gmbh | Verwendung von (1r, 2r)-3-(3-dimenthylamino-1- ethyl-2-methyl-propyl)-phenol zur behandlung von entzündungsschmerz |
-
2007
- 2007-04-25 SI SI200730498T patent/SI2012764T1/sl unknown
- 2007-04-25 DK DK07724562.9T patent/DK2012764T3/da active
- 2007-04-25 CA CA2650423A patent/CA2650423C/en active Active
- 2007-04-25 AT AT07724562T patent/ATE494889T1/de active
- 2007-04-25 KR KR1020087028929A patent/KR101396166B1/ko not_active Expired - Fee Related
- 2007-04-25 HR HR20110076T patent/HRP20110076T1/hr unknown
- 2007-04-25 CN CN2007800148115A patent/CN101431990B/zh not_active Expired - Fee Related
- 2007-04-25 AU AU2007247481A patent/AU2007247481B2/en not_active Ceased
- 2007-04-25 BR BRPI0710682A patent/BRPI0710682B8/pt active IP Right Grant
- 2007-04-25 ES ES07724562T patent/ES2356093T3/es active Active
- 2007-04-25 MX MX2008013779A patent/MX2008013779A/es active IP Right Grant
- 2007-04-25 JP JP2009506978A patent/JP5496653B2/ja not_active Expired - Fee Related
- 2007-04-25 PT PT07724562T patent/PT2012764E/pt unknown
- 2007-04-25 RU RU2008146816/15A patent/RU2442576C2/ru active
- 2007-04-25 EP EP07724562A patent/EP2012764B1/en active Active
- 2007-04-25 DE DE602007011913T patent/DE602007011913D1/de active Active
- 2007-04-25 PL PL07724562T patent/PL2012764T3/pl unknown
- 2007-04-25 WO PCT/EP2007/003632 patent/WO2007128413A1/en not_active Ceased
- 2007-04-25 NZ NZ571442A patent/NZ571442A/en not_active IP Right Cessation
-
2008
- 2008-10-06 EC EC2008008793A patent/ECSP088793A/es unknown
- 2008-10-23 IL IL194883A patent/IL194883A/en active IP Right Grant
- 2008-10-28 NO NO20084542A patent/NO341602B1/no unknown
- 2008-11-27 ZA ZA200810124A patent/ZA200810124B/xx unknown
-
2011
- 2011-04-05 CY CY20111100353T patent/CY1111369T1/el unknown
-
2013
- 2013-07-11 JP JP2013145481A patent/JP2013213045A/ja not_active Withdrawn
-
2017
- 2017-01-05 EC ECIEPI2017643A patent/ECSP17000643A/es unknown
- 2017-11-17 NO NO20171831A patent/NO343505B1/no unknown
Also Published As
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