[go: up one dir, main page]

NO20081198L - Fremgangsmate for a predikere eller monitorere en pasients respons til et medikament rettet mot en ErbB-reseptor - Google Patents

Fremgangsmate for a predikere eller monitorere en pasients respons til et medikament rettet mot en ErbB-reseptor

Info

Publication number
NO20081198L
NO20081198L NO20081198A NO20081198A NO20081198L NO 20081198 L NO20081198 L NO 20081198L NO 20081198 A NO20081198 A NO 20081198A NO 20081198 A NO20081198 A NO 20081198A NO 20081198 L NO20081198 L NO 20081198L
Authority
NO
Norway
Prior art keywords
patient
predicting
monitoring
procedure
response
Prior art date
Application number
NO20081198A
Other languages
English (en)
Norwegian (no)
Inventor
Kazuto Nishio
Hideharu Kimura
Kazuo Kasahara
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of NO20081198L publication Critical patent/NO20081198L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20081198A 2005-10-05 2008-03-06 Fremgangsmate for a predikere eller monitorere en pasients respons til et medikament rettet mot en ErbB-reseptor NO20081198L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2005003823 2005-10-05
PCT/GB2005/004036 WO2007039705A1 (fr) 2005-10-05 2005-10-20 Méthode pour prédire ou surveiller la réponse d'un patient à un médicament de récepteur erbb

Publications (1)

Publication Number Publication Date
NO20081198L true NO20081198L (no) 2008-06-30

Family

ID=36114238

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081198A NO20081198L (no) 2005-10-05 2008-03-06 Fremgangsmate for a predikere eller monitorere en pasients respons til et medikament rettet mot en ErbB-reseptor

Country Status (14)

Country Link
US (1) US20080286785A1 (fr)
EP (1) EP1931798A1 (fr)
JP (1) JP2009511008A (fr)
KR (1) KR20080028857A (fr)
CN (1) CN101351563A (fr)
AU (1) AU2005337051A1 (fr)
BR (1) BRPI0520530A2 (fr)
CA (1) CA2624613A1 (fr)
IL (1) IL189705A0 (fr)
NO (1) NO20081198L (fr)
NZ (1) NZ566387A (fr)
TW (1) TW200714716A (fr)
WO (1) WO2007039705A1 (fr)
ZA (1) ZA200802854B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2364495T3 (es) 2005-02-03 2011-09-05 The General Hospital Corporation Método para tratar cáncer resistente a gefitinib.
RU2451524C2 (ru) 2005-11-04 2012-05-27 Вайет Противоопухолевые комбинации с ингибиторами mtor, герцептином и/или hki-272
NZ579644A (en) 2007-02-16 2012-05-25 Merrimack Pharmaceuticals Inc Antibodies against erbb3 and uses thereof
US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
EP2915532B1 (fr) 2008-06-17 2016-10-19 Wyeth LLC Combinaisons antinéoplasiques contenant du HKI-272 et de la vinorelbine
EP4424375A3 (fr) 2008-08-04 2024-11-20 Wyeth LLC Combinaisons antinéoplasiques de nératinib et de capécitabine
US8623592B2 (en) 2008-08-15 2014-01-07 Merrimack Pharmaceuticals, Inc. Methods and systems for predicting response of cells to a therapeutic agent
ES2941894T3 (es) 2009-04-06 2023-05-26 Wyeth Llc Régimen de tratamiento que utiliza neratinib contra el cáncer de mama
SG176571A1 (en) * 2009-05-19 2012-01-30 Vivia Biotech Sl Methods for providing personalized medicine tests ex vivo for hematological neoplasms
JP2013510564A (ja) 2009-11-13 2013-03-28 パンガエア ビオテック、ソシエダッド、リミターダ 肺癌におけるチロシンキナーゼ阻害剤に対する応答を予測するための分子バイオマーカー
TWI630916B (zh) * 2009-11-13 2018-08-01 第一三共歐洲公司 供治療或預防人表皮生長因子受體-3(her-3)相關疾病之藥料和方法
SG183532A1 (en) 2010-03-11 2012-09-27 Merrimack Pharmaceuticals Inc Use of erbb3 inhibitors in the treatment of triple negative and basal-like breast cancers
EP3219814B1 (fr) * 2010-10-29 2023-02-15 ARKRAY, Inc. Sonde de détection de polymorphisme dans le gène egfr, amorce d'amplification et utilisation associée
WO2012065071A2 (fr) * 2010-11-12 2012-05-18 The Broad Institute Of Mit And Harvard Procédés de prédiction d'une réponse à une thérapie par un anticorps anti-egfr
EP2468883A1 (fr) 2010-12-22 2012-06-27 Pangaea Biotech S.L. Biomarqueurs moléculaires pour la prédiction de la réponse aux inhibiteurs de la tyrosine kinase dans le cancer du poumon
EP2492688A1 (fr) 2011-02-23 2012-08-29 Pangaea Biotech, S.A. Biomarqueurs moléculaires pour la prédiction de la réponse à un traitement antitumoral dans le cancer du poumon
CN103255201B (zh) * 2012-02-16 2017-07-14 江苏宏微特斯医药科技有限公司 一种基于Blocker引物和ARMS引物检测基因突变的方法和试剂盒
WO2013190089A1 (fr) 2012-06-21 2013-12-27 Pangaea Biotech, S.L. Biomarqueurs moléculaires permettant de prédire l'issue dans le cancer du poumon
CN105229173A (zh) * 2013-03-08 2016-01-06 豪夫迈·罗氏有限公司 Egfr突变血液测试
WO2015100459A2 (fr) 2013-12-27 2015-07-02 Merrimack Pharmaceuticals, Inc. Profils de biomarqueur pour prédire les résultats d'une thérapie cancéreuse utilisant des inhibiteurs d'erbb3 et/ou des chimiothérapies
CA2961437C (fr) * 2014-10-09 2019-01-15 F. Hoffmann-La Roche Ag Nouvelles mutations complexes dans le domaine kinase du recepteur de facteur de croissance epidermique
GB201507202D0 (en) * 2015-04-28 2015-06-10 Stfc Science & Technology Receptor tyosine kinase biomarkers
US10184006B2 (en) 2015-06-04 2019-01-22 Merrimack Pharmaceuticals, Inc. Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors
CN115844877B (zh) * 2017-01-10 2024-07-23 浙江嘉驰医药开发有限公司 拉索昔芬调节膜结合雌激素信号的应用及治疗癌症的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9403953D0 (sv) * 1994-07-15 1994-11-16 Pharmacia Biotech Ab Sequence-based diagnosis
US6759217B2 (en) * 1996-03-26 2004-07-06 Oncomedx, Inc. Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
GB9812768D0 (en) * 1998-06-13 1998-08-12 Zeneca Ltd Methods
JP2007527241A (ja) * 2004-03-01 2007-09-27 ユニバーシティ オブ シカゴ 上皮細胞成長因子受容体遺伝子プロモーターにおける多型
CN104774931B (zh) * 2004-03-31 2017-11-10 综合医院公司 测定癌症对表皮生长因子受体靶向性治疗反应性的方法
WO2005118876A2 (fr) * 2004-06-04 2005-12-15 Genentech, Inc. Mutations de egfr
GB2424886A (en) * 2005-04-04 2006-10-11 Dxs Ltd Polynucleotide primers against epidermal growth factor receptor and method of detecting gene mutations
US20060223178A1 (en) * 2005-04-05 2006-10-05 Tom Barber Devices and methods for magnetic enrichment of cells and other particles

Also Published As

Publication number Publication date
JP2009511008A (ja) 2009-03-19
WO2007039705A1 (fr) 2007-04-12
US20080286785A1 (en) 2008-11-20
EP1931798A1 (fr) 2008-06-18
NZ566387A (en) 2010-05-28
BRPI0520530A2 (pt) 2009-09-29
IL189705A0 (en) 2008-06-05
KR20080028857A (ko) 2008-04-01
ZA200802854B (en) 2009-06-24
AU2005337051A1 (en) 2007-04-12
TW200714716A (en) 2007-04-16
CN101351563A (zh) 2009-01-21
CA2624613A1 (fr) 2007-04-12

Similar Documents

Publication Publication Date Title
NO20081198L (no) Fremgangsmate for a predikere eller monitorere en pasients respons til et medikament rettet mot en ErbB-reseptor
DK1991697T3 (da) DNA-konformation (LOOP-strukturer) ved normal og anormal genekspression
WO2007134166A3 (fr) Dépistage en temps réel du virus de l'influenza
WO2007001342A3 (fr) Recueil de condensat d'haleine expiree (ebc) et systeme d'essai et procede associe
WO2007070376A8 (fr) Diagnostic, pronostic et suivi de la progression du lupus erythemateux systemique par analyse de microreseaux de leucocytes sanguins
GB2477053B (en) Droplet-based assay system
DK1745144T3 (da) Analysefremgangsmåde til opsporing af lægemidler på grundlag af in vitro-differentierede celler
WO2005076887A3 (fr) Procedes et systemes d'echantillonnage, de criblage et de diagnostic
WO2009146450A3 (fr) Procédés de surveillance des taux de médicaments immunosuppresseurs, de la fonction rénale, et de la fonction hépatique à l’aide d’échantillons de petit volume
ES2422735T3 (es) Procedimiento para la predicción de un riesgo de reacciones adversas a medicamentos mediante la determinación de HLA-B 1502
WO2001040517A3 (fr) Evaluation et prediction cliniques obtenues par analyse d"expression genique
WO2004096985A3 (fr) Procedes d'evaluation de la diversite biologique
WO2008112567A3 (fr) Procédé et appareil d'évaluation quantitative de troubles neuromoteurs
ATE527543T1 (de) Testvorrichtung zur schnelldiagnose
WO2007114986A3 (fr) Sondes coopératives et leurs procédés d'utilisation
WO2007001081A3 (fr) Methode discriminante individuelle et jeu ordonne d'echantillons, appareil et systeme pour un test discriminant individuel
WO2002012892A3 (fr) Panneaux multiples rapides de biomarqueurs des ait/avc dans des analyses sanguines en laboratoire
WO2019204340A3 (fr) Biomarqueur pour prédire l'allure d'un cheval et méthodes d'utilisation associées
WO2006060393A3 (fr) Analyse systemique biologique
WO2008145701A9 (fr) Procédé de prédiction de l'évolution d'un patient malade de manière critique
WO2005121362A3 (fr) Methode de quantification selective d'isoformes de vegf dans un echantillon biologique et ses utilisations
WO2004113574A3 (fr) Methodes de depistage d'une maladie
DK2274623T3 (da) Fremgangsmåde til diagnosticering af pulmonal arteriel hypertension
WO2005056839A3 (fr) Amorces et sondes pour detecter des genotypes du papillomavirus humain genital
WO2007113685A3 (fr) UTILISATION D'UNE CHAÎNE α DE SPECTRINE CERÉBRALE ET DE FRAGMENTS DE CELLE-CI POUR DIAGNOSTIQUER DES MALADIES CÉRÉBRALES

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application