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NO20070976L - Pyrazolderivater - Google Patents

Pyrazolderivater

Info

Publication number
NO20070976L
NO20070976L NO20070976A NO20070976A NO20070976L NO 20070976 L NO20070976 L NO 20070976L NO 20070976 A NO20070976 A NO 20070976A NO 20070976 A NO20070976 A NO 20070976A NO 20070976 L NO20070976 L NO 20070976L
Authority
NO
Norway
Prior art keywords
formula
salt
cox
pyrazole
compound
Prior art date
Application number
NO20070976A
Other languages
English (en)
Inventor
Naoaki Kanaya
Toshiyuki Watanabe
Takashi Ishiyama
Yuichi Ochiai
Ryo Muto
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of NO20070976L publication Critical patent/NO20070976L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Forbindelse representert ved Formel (I): hvor Ar1 representerer Formel (II): Ar2 representerer en 5- eller 6-leddet aromatisk heterocyklisk gruppe som kan være substituert; og X representerer Formel (III): et salt derav eller et solvat av forbindelsen eller saltet. Et kraftig blodplateaggregerings-undertrykkende middel som ikke hemmer COX-1 og COX-2 er gitt.
NO20070976A 2004-08-06 2007-02-21 Pyrazolderivater NO20070976L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004230012 2004-08-06
PCT/JP2005/014544 WO2006014005A1 (ja) 2004-08-06 2005-08-08 ピラゾール誘導体

Publications (1)

Publication Number Publication Date
NO20070976L true NO20070976L (no) 2007-04-24

Family

ID=35787279

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070976A NO20070976L (no) 2004-08-06 2007-02-21 Pyrazolderivater

Country Status (12)

Country Link
US (1) US20070254881A1 (no)
EP (1) EP1785418A4 (no)
JP (1) JPWO2006014005A1 (no)
KR (1) KR20070048771A (no)
CN (1) CN101001852A (no)
AU (1) AU2005268023A1 (no)
CA (1) CA2578261A1 (no)
IL (1) IL180889A0 (no)
MX (1) MX2007001555A (no)
NO (1) NO20070976L (no)
RU (1) RU2007108296A (no)
WO (1) WO2006014005A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2525217T3 (es) * 2005-06-27 2014-12-19 Exelixis Patent Company Llc Moduladores de LXR basados en imidazol
JP2009184925A (ja) * 2006-11-02 2009-08-20 Dai Ichi Seiyaku Co Ltd ５−（１ｈ−１，２，３−トリアゾール−４−イル）−１ｈ−ピラゾール誘導体
US7977358B2 (en) * 2007-07-26 2011-07-12 Hoffmann-La Roche Inc. Pyrazol derivatives
JP5976778B2 (ja) * 2011-04-11 2016-08-24 ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ キナーゼ阻害剤としてのピラゾリル−ピリミジン誘導体
CN102321045B (zh) * 2011-06-13 2013-07-17 陕西瑞科新材料股份有限公司 一种制备高吗啉盐酸盐的方法
EP3842100A1 (en) 2019-12-24 2021-06-30 The Board Of Regents Of The University Of Texas System Anti-malarial agents
CN114920682A (zh) * 2022-03-17 2022-08-19 重庆医药高等专科学校 一种将脯氨酸还原成脯氨醇的方法及1-甲基吡咯烷-2-丙烯酸的制备方法
CN120463596B (zh) * 2025-07-11 2025-10-21 昆山协鑫光电材料有限公司 一种pcbm及其制备方法和应用以及用于制备pcbm的装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH27357A (en) * 1989-09-22 1993-06-21 Fujisawa Pharmaceutical Co Pyrazole derivatives and pharmaceutical compositions comprising the same
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
WO2004002409A2 (en) * 2002-06-27 2004-01-08 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
EP1591443B1 (en) * 2003-02-07 2010-08-25 Daiichi Sankyo Company, Limited Pyrazole derivative
WO2004094407A1 (ja) * 2003-04-21 2004-11-04 Daiichi Pharmaceutical Co. Ltd. ５員複素環誘導体
WO2006004027A1 (ja) * 2004-07-01 2006-01-12 Daiichi Pharmaceutical Co., Ltd. ピラゾール誘導体

Also Published As

Publication number Publication date
CA2578261A1 (en) 2006-02-09
KR20070048771A (ko) 2007-05-09
JPWO2006014005A1 (ja) 2008-05-01
IL180889A0 (en) 2007-07-04
AU2005268023A1 (en) 2006-02-09
MX2007001555A (es) 2007-04-10
EP1785418A4 (en) 2009-11-11
US20070254881A1 (en) 2007-11-01
WO2006014005A1 (ja) 2006-02-09
CN101001852A (zh) 2007-07-18
EP1785418A1 (en) 2007-05-16
RU2007108296A (ru) 2008-09-20

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application