NO20070458L - Aryl-pyridinderivater som 11-Beta-HSD1 inhibitorer - Google Patents
Aryl-pyridinderivater som 11-Beta-HSD1 inhibitorerInfo
- Publication number
- NO20070458L NO20070458L NO20070458A NO20070458A NO20070458L NO 20070458 L NO20070458 L NO 20070458L NO 20070458 A NO20070458 A NO 20070458A NO 20070458 A NO20070458 A NO 20070458A NO 20070458 L NO20070458 L NO 20070458L
- Authority
- NO
- Norway
- Prior art keywords
- beta
- aryl
- pyridine derivatives
- hsd1 inhibitors
- hsd1
- Prior art date
Links
- 102100036506 11-beta-hydroxysteroid dehydrogenase 1 Human genes 0.000 title 1
- 101710186107 11-beta-hydroxysteroid dehydrogenase 1 Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04103639 | 2004-07-28 | ||
| PCT/EP2005/007894 WO2006010546A2 (fr) | 2004-07-28 | 2005-07-20 | Derives d'aryl-pyridine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20070458L true NO20070458L (no) | 2007-01-24 |
Family
ID=35427898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20070458A NO20070458L (no) | 2004-07-28 | 2007-01-24 | Aryl-pyridinderivater som 11-Beta-HSD1 inhibitorer |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US7528159B2 (fr) |
| EP (1) | EP1789041B1 (fr) |
| JP (1) | JP4690402B2 (fr) |
| KR (1) | KR100926842B1 (fr) |
| CN (1) | CN100589803C (fr) |
| AR (1) | AR049739A1 (fr) |
| AT (1) | ATE400271T1 (fr) |
| AU (1) | AU2005266531B2 (fr) |
| BR (1) | BRPI0513864A (fr) |
| CA (1) | CA2574875C (fr) |
| DE (1) | DE602005008079D1 (fr) |
| DK (1) | DK1789041T3 (fr) |
| ES (1) | ES2309789T3 (fr) |
| HR (1) | HRP20080477T3 (fr) |
| IL (1) | IL180481A (fr) |
| MX (1) | MX2007000789A (fr) |
| MY (1) | MY138941A (fr) |
| NO (1) | NO20070458L (fr) |
| NZ (1) | NZ552398A (fr) |
| PL (1) | PL1789041T3 (fr) |
| PT (1) | PT1789041E (fr) |
| RU (1) | RU2374239C2 (fr) |
| SI (1) | SI1789041T1 (fr) |
| TW (1) | TW200608972A (fr) |
| WO (1) | WO2006010546A2 (fr) |
| ZA (1) | ZA200700181B (fr) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE400271T1 (de) * | 2004-07-28 | 2008-07-15 | Hoffmann La Roche | Aryl-pyridinderivate als 11-beta-hsd1-hemmer |
| WO2006106423A2 (fr) * | 2005-04-07 | 2006-10-12 | Pfizer Inc. | Nouveaux composes de derives aminosulfonyles |
| CA2641609A1 (fr) * | 2006-02-07 | 2007-08-16 | Wyeth | Inhibiteurs 11-beta hsd1 |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| AU2007283113A1 (en) | 2006-08-08 | 2008-02-14 | Sanofi-Aventis | Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use |
| EP2025674A1 (fr) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament |
| EP2310372B1 (fr) | 2008-07-09 | 2012-05-23 | Sanofi | Composés hétérocycliques, leur procédé de préparation, médicaments les contenant et leur utilisation |
| US20100022572A1 (en) | 2008-07-18 | 2010-01-28 | Kowa Company, Ltd. | Novel spiro compound and medicine comprising the same |
| WO2010023931A1 (fr) | 2008-08-29 | 2010-03-04 | 興和株式会社 | Dérivé 1-adamantylazétidine-2-one et préparation pharmaceutique comprenant ce dérivé |
| WO2010050191A1 (fr) | 2008-10-29 | 2010-05-06 | 興和株式会社 | Dérivé 1,2-diazétidin-3-one et agent pharmaceutique le comprenant |
| WO2010068601A1 (fr) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | Hydrate de fluoroglycoside hétéroaromatique cristallin, ses procédés de fabrication, ses procédés d'utilisation et compositions pharmaceutiques le contenant |
| SG175925A1 (en) | 2009-05-15 | 2011-12-29 | Novartis Ag | Aryl pyridine as aldosterone synthase inhibitors |
| ES2443016T3 (es) | 2009-08-26 | 2014-02-17 | Sanofi | Nuevos hidratos cristalinos de fluoroglicósidos heteroaromáticos, productos farmacéuticos que comprenden estos compuestos, y su empleo |
| WO2011068927A2 (fr) * | 2009-12-04 | 2011-06-09 | Abbott Laboratories | Inhibiteurs de la 11-β-hydroxystéroïde déshydrogénase de type 1 (11b-hsd1) et leurs utilisations |
| WO2011107494A1 (fr) | 2010-03-03 | 2011-09-09 | Sanofi | Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation |
| EP2582709B1 (fr) | 2010-06-18 | 2018-01-24 | Sanofi | Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| EP2683705B1 (fr) | 2011-03-08 | 2015-04-22 | Sanofi | Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation |
| EP2683700B1 (fr) | 2011-03-08 | 2015-02-18 | Sanofi | Dérivés d'oxathiazine tétra-substitués, leur procédé de fabrication, leur utilisation comme médicament ainsi que médicaments en étant pourvu et leur utilisation |
| US8809325B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof |
| US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| EP2683699B1 (fr) | 2011-03-08 | 2015-06-24 | Sanofi | Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation |
| US8809324B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
| EP2766349B1 (fr) | 2011-03-08 | 2016-06-01 | Sanofi | Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation |
| WO2012120057A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Nouveaux dérivés phényl-oxathiazine substitués, procédé pour leur préparation, agent pharmaceutique contenant ces composés et leur utilisation |
| US8846666B2 (en) | 2011-03-08 | 2014-09-30 | Sanofi | Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| CN103443080B (zh) * | 2011-03-16 | 2016-10-12 | 田边三菱制药株式会社 | 具有trpm8拮抗活性的磺酰胺化合物 |
| WO2013037390A1 (fr) | 2011-09-12 | 2013-03-21 | Sanofi | Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
| EP2760862B1 (fr) | 2011-09-27 | 2015-10-21 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase |
| CA2865071C (fr) | 2012-02-22 | 2020-06-23 | Sanford-Burnham Medical Research Institute | Composes sulfonamides et leurs utilisations en tant qu'inhibiteurs de tnap |
| KR20150092162A (ko) * | 2012-12-10 | 2015-08-12 | 에프. 호프만-라 로슈 아게 | RORc 조절인자로서 벤질 설폰아미드 유도체 |
| CN105175323B (zh) * | 2015-09-16 | 2017-12-22 | 浙江海翔药业股份有限公司 | 一种制备2‑（4‑乙酰胺基苯磺酰基）胺基吡啶的方法 |
| US20210221784A1 (en) * | 2018-02-05 | 2021-07-22 | Université De Strasbourg | Compounds and compositions for the treatment of pain |
| CA3093445A1 (fr) | 2018-03-08 | 2019-11-28 | Incyte Corporation | Composes d'aminopyrazine diol utilises comme inhibiteurs de pi3k-.gamma. |
| US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
| KR102418518B1 (ko) * | 2020-08-05 | 2022-07-07 | 성균관대학교산학협력단 | 설퍼 일라이드를 이용한 n-헤테로고리의 선택적 알킬화 방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2159938A1 (fr) * | 1994-10-07 | 1996-04-08 | Hiroaki Yanagisawa | Derives d'oximes; methode de preparation et applications therapeutiques |
| DE60236541D1 (de) | 2001-11-22 | 2010-07-08 | Biovitrum Ab | Inhibitoren von 11-beta-hydroxysteroiddehydrogenase typ 1 |
| BR0214344A (pt) * | 2001-11-22 | 2004-09-14 | Biovitrum Ab | Inibidores de 11 - beta - hidroxi esteróide desidrogenase tipo 1 |
| MXPA05001009A (es) * | 2002-07-27 | 2005-05-16 | Astrazeneca Ab | Cetonas. |
| ATE400271T1 (de) * | 2004-07-28 | 2008-07-15 | Hoffmann La Roche | Aryl-pyridinderivate als 11-beta-hsd1-hemmer |
-
2005
- 2005-07-20 AT AT05776709T patent/ATE400271T1/de active
- 2005-07-20 JP JP2007522984A patent/JP4690402B2/ja not_active Expired - Fee Related
- 2005-07-20 CN CN200580025005A patent/CN100589803C/zh not_active Expired - Fee Related
- 2005-07-20 PT PT05776709T patent/PT1789041E/pt unknown
- 2005-07-20 ES ES05776709T patent/ES2309789T3/es not_active Expired - Lifetime
- 2005-07-20 SI SI200530343T patent/SI1789041T1/sl unknown
- 2005-07-20 CA CA2574875A patent/CA2574875C/fr not_active Expired - Fee Related
- 2005-07-20 DK DK05776709T patent/DK1789041T3/da active
- 2005-07-20 PL PL05776709T patent/PL1789041T3/pl unknown
- 2005-07-20 MX MX2007000789A patent/MX2007000789A/es active IP Right Grant
- 2005-07-20 DE DE602005008079T patent/DE602005008079D1/de not_active Expired - Lifetime
- 2005-07-20 AU AU2005266531A patent/AU2005266531B2/en not_active Ceased
- 2005-07-20 HR HR20080477T patent/HRP20080477T3/xx unknown
- 2005-07-20 NZ NZ552398A patent/NZ552398A/en not_active IP Right Cessation
- 2005-07-20 BR BRPI0513864-7A patent/BRPI0513864A/pt not_active IP Right Cessation
- 2005-07-20 KR KR1020077002036A patent/KR100926842B1/ko not_active Expired - Fee Related
- 2005-07-20 WO PCT/EP2005/007894 patent/WO2006010546A2/fr not_active Ceased
- 2005-07-20 EP EP05776709A patent/EP1789041B1/fr not_active Expired - Lifetime
- 2005-07-20 RU RU2007107189/04A patent/RU2374239C2/ru not_active IP Right Cessation
- 2005-07-25 TW TW094125138A patent/TW200608972A/zh unknown
- 2005-07-26 AR ARP050103098A patent/AR049739A1/es unknown
- 2005-07-26 US US11/189,598 patent/US7528159B2/en not_active Expired - Fee Related
- 2005-07-26 MY MYPI20053431A patent/MY138941A/en unknown
-
2007
- 2007-01-01 IL IL180481A patent/IL180481A/en not_active IP Right Cessation
- 2007-01-05 ZA ZA200700181A patent/ZA200700181B/xx unknown
- 2007-01-24 NO NO20070458A patent/NO20070458L/no not_active Application Discontinuation
-
2009
- 2009-02-17 US US12/372,244 patent/US8211913B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |