NO20065776L - Fremgangsmate for fremstilling av 1,4-difenylazetidinonderivater - Google Patents
Fremgangsmate for fremstilling av 1,4-difenylazetidinonderivaterInfo
- Publication number
- NO20065776L NO20065776L NO20065776A NO20065776A NO20065776L NO 20065776 L NO20065776 L NO 20065776L NO 20065776 A NO20065776 A NO 20065776A NO 20065776 A NO20065776 A NO 20065776A NO 20065776 L NO20065776 L NO 20065776L
- Authority
- NO
- Norway
- Prior art keywords
- mean
- anion
- derivatives
- alkyl
- groups
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001450 anions Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- HZVHFGGPXITZGN-UHFFFAOYSA-N 1,4-diphenylazetidin-2-one Chemical class O=C1CC(C=2C=CC=CC=2)N1C1=CC=CC=C1 HZVHFGGPXITZGN-UHFFFAOYSA-N 0.000 abstract 1
- 150000001336 alkenes Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- -1 phosphonium ions Chemical class 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Det er beskrevet en fremgangsmåte for fremstilling av 1,4-difenyl azetidinon derivater fra egnet beskyttede (3-substituerte aminosyrer i nærvær av siluleringsmidler. Fremgangsmåten anvender ringslutningskatalysatorer som omfatter fosfoniumioner som kationet av formel (XII), og ioner av de følgende generelle formlene (a), (b), (c) eller (d) som anion. I de nevnte formlene er symbolene, substituentene og indeksene definert som følger: Z = C=O, C=S, S=O, SO2 eller C=NR20; K = O, S, NR21 eller CR22R23; L = NR24 eller CR25R26; n = 0 eller 1; M = O, C=O, NR27 eller CR28R29; Q = O, S, NR30, CR31R32, C=O, C=S, S=O, SO2 eller C=NR34; R = CR35 eller N; T = CR36 eller N; U = CR37 eller N; V = CR38 eller N; gruppene R16 til R19 kan for eksempel bety aryl eller (Ci-Ci5)alkyl, aryl(Ci-Cio)alken, og gruppene R20 til R32 og R34 til R38 kan i tillegg bety H eller heteroaryl; R39 og R40 betyr for eksempel (Ci-Ce)alkyl. Anionet kan også være R41O", R42COO' eller Cl", Br" eller I" (kombinert med Ag2O).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE200410025071 DE102004025071B4 (de) | 2004-05-21 | 2004-05-21 | Verfahren zur Herstellung von Diphenylazetidinon-Derivaten |
| PCT/EP2005/005498 WO2005113496A1 (de) | 2004-05-21 | 2005-05-20 | Verfahren zur herstellung von 1,4-diphenylazetidinon-derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20065776L true NO20065776L (no) | 2006-12-13 |
Family
ID=35456151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20065776A NO20065776L (no) | 2004-05-21 | 2006-12-13 | Fremgangsmate for fremstilling av 1,4-difenylazetidinonderivater |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN100509781C (no) |
| DE (1) | DE102004025071B4 (no) |
| NO (1) | NO20065776L (no) |
| ZA (1) | ZA200608708B (no) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104710315A (zh) * | 2013-12-11 | 2015-06-17 | 中国科学院大连化学物理研究所 | 一种α,β-不饱和硝基烯烃化合物的绿色合成方法 |
| CN108218742B (zh) * | 2017-12-11 | 2021-08-27 | 绍兴文理学院 | 一种酮肟的制备方法 |
| CN117164482B (zh) * | 2023-08-18 | 2025-11-25 | 华南理工大学 | 一种离子型化合物和一种催化合成环碳酸酯的方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0707567B1 (en) * | 1993-07-09 | 2001-09-12 | Schering Corporation | Process for the synthesis of azetidinones |
-
2004
- 2004-05-21 DE DE200410025071 patent/DE102004025071B4/de not_active Expired - Fee Related
-
2005
- 2005-05-20 CN CNB2005800155919A patent/CN100509781C/zh not_active Expired - Fee Related
-
2006
- 2006-10-18 ZA ZA200608708A patent/ZA200608708B/en unknown
- 2006-12-13 NO NO20065776A patent/NO20065776L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE102004025071A1 (de) | 2005-12-15 |
| CN1953961A (zh) | 2007-04-25 |
| CN100509781C (zh) | 2009-07-08 |
| ZA200608708B (en) | 2008-07-30 |
| DE102004025071B4 (de) | 2006-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |