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NO20060544L - Enzymatiske prosesser for produksjon av 4-substituerte 3-hydroksysmorsyrederivater og naerliggende cyano, hydroksy substituerte karboksylsyre estere - Google Patents

Enzymatiske prosesser for produksjon av 4-substituerte 3-hydroksysmorsyrederivater og naerliggende cyano, hydroksy substituerte karboksylsyre estere

Info

Publication number
NO20060544L
NO20060544L NO20060544A NO20060544A NO20060544L NO 20060544 L NO20060544 L NO 20060544L NO 20060544 A NO20060544 A NO 20060544A NO 20060544 A NO20060544 A NO 20060544A NO 20060544 L NO20060544 L NO 20060544L
Authority
NO
Norway
Prior art keywords
acid derivatives
substituted
hydroxybutyric acid
nearby
cyano
Prior art date
Application number
NO20060544A
Other languages
English (en)
Inventor
Roger Sheldon
Christopher S Davis
John H Grate
David R Gray
John M Gruber
Gjalr W Huisman
Lisa Marie Newman
Steven K Ma
Li A Wang
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/639,159 external-priority patent/US7125693B2/en
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of NO20060544L publication Critical patent/NO20060544L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/002Nitriles (-CN)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Foreliggende oppfinnelse tilveiebringer fremgangsmåter og sammensetninger for fremstilling av 4-substituerte 3-hydroksysmørsyrederivater ved halohydrindehalogenase-katalysert omdannelse av 4-halo-3-hydroksysmørsyrederivater. Foreliggende oppfinnelse tilveiebringer videre fremgangsmåter og sammensetninger for fremstilling av 4-halo-3-hydroksysmørsyrederivater ved keto-reduktase-katalysert omdannelse av 4-halo-3-hydroksysmørsyrederivater. Foreliggende oppfinnelse tilveiebringer også fremgangsmåter og sammensetninger for fremstilling av nærliggende cyano, hydroksysubstituerte karboksylsyreestere.
NO20060544A 2003-08-11 2006-02-02 Enzymatiske prosesser for produksjon av 4-substituerte 3-hydroksysmorsyrederivater og naerliggende cyano, hydroksy substituerte karboksylsyre estere NO20060544L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/639,159 US7125693B2 (en) 2002-08-09 2003-08-11 Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
PCT/US2004/004819 WO2005018579A2 (en) 2003-08-11 2004-02-18 Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters
US10/782,258 US7132267B2 (en) 2002-08-09 2004-02-18 Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters

Publications (1)

Publication Number Publication Date
NO20060544L true NO20060544L (no) 2006-03-13

Family

ID=34221830

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060544A NO20060544L (no) 2003-08-11 2006-02-02 Enzymatiske prosesser for produksjon av 4-substituerte 3-hydroksysmorsyrederivater og naerliggende cyano, hydroksy substituerte karboksylsyre estere

Country Status (10)

Country Link
US (2) US7132267B2 (no)
EP (1) EP1660669A4 (no)
JP (1) JP2007502111A (no)
KR (1) KR20060071397A (no)
AU (1) AU2004266100A1 (no)
BR (1) BRPI0413498A (no)
CA (1) CA2535353A1 (no)
MX (1) MXPA06001718A (no)
NO (1) NO20060544L (no)
WO (1) WO2005018579A2 (no)

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US7588928B2 (en) * 2003-08-11 2009-09-15 Codexis, Inc. Halohydrin dehalogenases and related polynucleotides
US7824898B2 (en) * 2003-08-11 2010-11-02 Codexis, Inc. Halohydrin dehalogenases and related polynucleotides
KR20060071397A (ko) 2003-08-11 2006-06-26 코덱시스, 인코포레이티드 4-치환된 3-히드록시부티르산 유도체 및 이웃자리 시아노,히드록시 치환된 카르복실산 에스테르의 효소적 제조 방법
US7816111B2 (en) * 2003-08-11 2010-10-19 Codexis, Inc. Glucose dehydrogenase polypeptides and related polynucleotides
US7541171B2 (en) * 2003-08-11 2009-06-02 Codexis, Inc. Halohydrin dehalogenases and related polynucleotides
WO2005017135A1 (en) 2003-08-11 2005-02-24 Codexis, Inc. Improved ketoreductase polypeptides and related polynucleotides

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MXPA06001718A (es) 2006-05-19
WO2005018579A2 (en) 2005-03-03
US7132267B2 (en) 2006-11-07
EP1660669A4 (en) 2008-10-01
KR20060071397A (ko) 2006-06-26
US20070161094A1 (en) 2007-07-12
EP1660669A2 (en) 2006-05-31
AU2004266100A1 (en) 2005-03-03
CA2535353A1 (en) 2005-03-03
BRPI0413498A (pt) 2006-10-17
US7807423B2 (en) 2010-10-05
US20040214297A1 (en) 2004-10-28
WO2005018579A3 (en) 2005-04-14

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