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NO20055891L - Kinazolinderivater som aurorakinaseinhibitorer - Google Patents

Kinazolinderivater som aurorakinaseinhibitorer

Info

Publication number
NO20055891L
NO20055891L NO20055891A NO20055891A NO20055891L NO 20055891 L NO20055891 L NO 20055891L NO 20055891 A NO20055891 A NO 20055891A NO 20055891 A NO20055891 A NO 20055891A NO 20055891 L NO20055891 L NO 20055891L
Authority
NO
Norway
Prior art keywords
quinazoline derivatives
aurorakinase
inhibitors
treatment
well
Prior art date
Application number
NO20055891A
Other languages
English (en)
Inventor
Frederic Henri Jung
Andrew Austen Mortlock
Nicola Murdoch Heron
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33522456&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20055891(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20055891L publication Critical patent/NO20055891L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Kinazolin-derivater med formel (I) for anvendelse ved behandling av proliferative sykdommer så som kreft, og ved fremstilling av medikamenter for anvendelse ved behandling av proliferative sykdommer, samt fremgangsmåter for fremstilling av dem, så vel som farmasøytiske preparater som inneholder dem som aktiv bestanddel.
NO20055891A 2003-06-17 2005-12-12 Kinazolinderivater som aurorakinaseinhibitorer NO20055891L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03291463 2003-06-17
PCT/GB2004/002564 WO2004113324A1 (en) 2003-06-17 2004-06-14 Chinazoline derivatives as aurora kinase inhibitors

Publications (1)

Publication Number Publication Date
NO20055891L true NO20055891L (no) 2006-02-07

Family

ID=33522456

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055891A NO20055891L (no) 2003-06-17 2005-12-12 Kinazolinderivater som aurorakinaseinhibitorer

Country Status (16)

Country Link
US (1) US20060178382A1 (no)
EP (1) EP1644361A1 (no)
JP (1) JP2006527748A (no)
KR (1) KR20060011891A (no)
CN (1) CN1835945A (no)
AR (1) AR045694A1 (no)
AU (1) AU2004249477A1 (no)
BR (1) BRPI0411503A (no)
CA (1) CA2529250A1 (no)
IL (1) IL172375A0 (no)
MX (1) MXPA05013825A (no)
NO (1) NO20055891L (no)
TW (1) TW200505452A (no)
UY (1) UY28366A1 (no)
WO (1) WO2004113324A1 (no)
ZA (1) ZA200510257B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0409427A (pt) * 2003-04-16 2006-04-18 Astrazeneca Ab composto, uso do mesmo, composição farmacêutica, método de tratamento de um humano sofrendo de uma doença hiperproliferativa, e, processo para a preparação de um composto ou de um sal, éster ou pró-droga farmaceuticamente aceitáveis do mesmo
ES2308182T3 (es) * 2003-06-02 2008-12-01 Astrazeneca Ab Derivadosde (3-((quinazolin-4-il)amino)-1h-pirazol-1-il)acetamida y compuestos relacionados como inhibidores de quinasas aurora para el tratamiento de enfermedades proliferativas tales como el cancer.
US7572914B2 (en) 2003-12-19 2009-08-11 Takeda Pharmaceutical Company Limited Kinase inhibitors
US7550598B2 (en) 2004-08-18 2009-06-23 Takeda Pharmaceutical Company Limited Kinase inhibitors
CA2581516C (en) 2004-10-12 2013-06-11 Astrazeneca Ab Quinazoline derivatives
EP1812439B2 (en) 2004-10-15 2017-12-06 Takeda Pharmaceutical Company Limited Kinase inhibitors
ATE421510T1 (de) * 2005-03-28 2009-02-15 Bristol Myers Squibb Co Kompetitive atp-kinasehemmer
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
UY30183A1 (es) 2006-03-02 2007-10-31 Astrazeneca Ab Derivados de quinolina
EP1994023A1 (en) * 2006-03-02 2008-11-26 AstraZeneca AB Quinazoline derivatives
US20070287706A1 (en) * 2006-05-18 2007-12-13 Dickson John K Jr Certain substituted quinolones, compositions, and uses thereof
GB0619342D0 (en) * 2006-09-30 2006-11-08 Vernalis R&D Ltd New chemical compounds
BRPI0719883A2 (pt) 2006-10-09 2015-05-05 Takeda Pharmaceutical Inibidores de quinase
US20110033461A1 (en) * 2008-03-12 2011-02-10 Vladimir Ratushny Combination Therapy for the Treatment of Cancer
US11053223B2 (en) * 2017-04-27 2021-07-06 Astrazeneca Ab Phenoxyquinazoline compounds and their use in treating cancer
MX389244B (es) 2017-04-27 2025-03-20 Astrazeneca Ab Compuestos de c5-anilinoquinazolina y su uso en el tratamiento del cancer
KR20190043842A (ko) 2017-10-19 2019-04-29 건국대학교 산학협력단 피리미딘-2-아민 유도체, 이의 제조방법 및 이를 포함하는 항암제
CN110372666B (zh) * 2018-04-13 2022-11-08 华东理工大学 喹唑啉类化合物作为egfr三突变抑制剂及其应用
CN113692276A (zh) * 2019-02-19 2021-11-23 加利福尼亚大学董事会 Nurr1受体调节剂
KR102061458B1 (ko) 2019-08-14 2019-12-31 건국대학교 산학협력단 피리미딘-2-아민 유도체, 이의 제조방법 및 이를 포함하는 항암제
CN112939948B (zh) * 2019-12-11 2022-05-17 苏州美诺医药科技有限公司 新型含喹唑啉类化合物及其中间体与应用
CN113200964B (zh) * 2021-04-25 2022-07-05 南方医科大学南方医院 18f标记的egfr正电子显像剂及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9922171D0 (en) * 1999-09-21 1999-11-17 Zeneca Ltd Chemical compounds
ES2305081T3 (es) * 2000-06-28 2008-11-01 Astrazeneca Ab Derivados de quinozolina sustituidos y su uso como inhibidores.
AU2002350105A1 (en) * 2001-06-21 2003-01-08 Ariad Pharmaceuticals, Inc. Novel quinazolines and uses thereof
MXPA04006260A (es) * 2001-12-24 2005-03-31 Astrazeneca Ab Derivados de quinazolina sustituidos como inhibidores de cinasas aurora.

Also Published As

Publication number Publication date
ZA200510257B (en) 2007-05-30
AR045694A1 (es) 2005-11-09
WO2004113324A1 (en) 2004-12-29
UY28366A1 (es) 2005-01-31
BRPI0411503A (pt) 2006-07-25
TW200505452A (en) 2005-02-16
AU2004249477A1 (en) 2004-12-29
KR20060011891A (ko) 2006-02-03
IL172375A0 (en) 2009-02-11
CA2529250A1 (en) 2004-12-29
CN1835945A (zh) 2006-09-20
EP1644361A1 (en) 2006-04-12
JP2006527748A (ja) 2006-12-07
MXPA05013825A (es) 2006-02-28
US20060178382A1 (en) 2006-08-10

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