NO20053077L - Terapeutiske formuleringer for behandling av beta-amyloid-relaterte sykdommer. - Google Patents
Terapeutiske formuleringer for behandling av beta-amyloid-relaterte sykdommer.Info
- Publication number
- NO20053077L NO20053077L NO20053077A NO20053077A NO20053077L NO 20053077 L NO20053077 L NO 20053077L NO 20053077 A NO20053077 A NO 20053077A NO 20053077 A NO20053077 A NO 20053077A NO 20053077 L NO20053077 L NO 20053077L
- Authority
- NO
- Norway
- Prior art keywords
- amyloid
- treatment
- related diseases
- agent
- beta
- Prior art date
Links
- 102000013455 Amyloid beta-Peptides Human genes 0.000 title abstract 3
- 108010090849 Amyloid beta-Peptides Proteins 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 230000007541 cellular toxicity Effects 0.000 abstract 1
- 235000015872 dietary supplement Nutrition 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229940126585 therapeutic drug Drugs 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
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- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Marine Sciences & Fisheries (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Anesthesiology (AREA)
- Oncology (AREA)
Abstract
Denne oppfinnelse angår metoder og farmasøytiske preparater for behandling av amyloid-ß-relaterte sykdommer, innbefattende Alzheimers sykdom. Oppfinnelsen innbefatter for eksempel en metode for samtidig terapeutisk behandling av et individ, omfattende administrering av en effektiv mengde av et første middel og et andre middel, hvor det første middel behandler en amyloid-ß-sykdom, neurodegenerasjon eller celletoksisitet; og det andre middel er et terapeutisk medikament eller næringssupplement.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43637902P | 2002-12-24 | 2002-12-24 | |
| US48221403P | 2003-06-23 | 2003-06-23 | |
| PCT/CA2003/002011 WO2004058258A1 (en) | 2002-12-24 | 2003-12-24 | Therapeutic formulations for the treatment of beta-amyloid related diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20053077D0 NO20053077D0 (no) | 2005-06-23 |
| NO20053077L true NO20053077L (no) | 2005-09-22 |
Family
ID=32685452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20053077A NO20053077L (no) | 2002-12-24 | 2005-06-23 | Terapeutiske formuleringer for behandling av beta-amyloid-relaterte sykdommer. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060135403A1 (no) |
| EP (2) | EP1581203A1 (no) |
| JP (2) | JP2006512417A (no) |
| KR (1) | KR20050101537A (no) |
| AU (2) | AU2003292936A1 (no) |
| BR (1) | BR0317747A (no) |
| CA (2) | CA2511599A1 (no) |
| EA (1) | EA012325B1 (no) |
| IL (1) | IL169338A0 (no) |
| MX (1) | MXPA05006940A (no) |
| NO (1) | NO20053077L (no) |
| NZ (1) | NZ541282A (no) |
| WO (2) | WO2004058258A1 (no) |
Families Citing this family (119)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| DK1628663T3 (da) * | 2003-05-15 | 2010-03-08 | Roskamp Res Llc | Fremgangsmåde til fremstilling af medikamenter til reduktion af amyloid-aflejring, amyloid-neurotoksicitet og mikrogliose |
| AU2004251511A1 (en) * | 2003-06-23 | 2005-01-06 | Neurochem (International) Limited | Treatment of protein aggregation disorders |
| AU2011250847B2 (en) * | 2003-06-23 | 2013-06-20 | Bhi Limited Partnership | Methods and compositions for treating amyloid-related diseases |
| US20050142191A1 (en) | 2003-06-23 | 2005-06-30 | Neurochem (International) Limited | Pharmaceutical formulations of amyloid inhibiting compounds |
| CA2529256A1 (en) * | 2003-06-23 | 2004-12-29 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| CA2824106A1 (en) * | 2003-08-29 | 2005-03-10 | Ono Pharmaceutical Co., Ltd. | Compound capable of binding s1p receptor and pharmaceutical use thereof |
| CA2549552A1 (en) * | 2003-12-17 | 2005-06-30 | Elan Pharmaceuticals, Inc. | A.beta. immunogenic peptide carrier conjugates and methods of producing same |
| AU2005232447A1 (en) * | 2004-04-14 | 2005-10-27 | Warner-Lambert Company Llc | Therapeutic combination for treatment of Alzheimers disease |
| CA2582385A1 (en) * | 2004-06-18 | 2005-12-18 | Neurochem (International) Limited | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| JP4717537B2 (ja) * | 2004-08-31 | 2011-07-06 | 株式会社 資生堂 | 皮膚外用組成物 |
| CA2586111A1 (en) * | 2004-11-12 | 2006-06-08 | Neurochem (International) Limited | Methods and fluorinated compositions for treating amyloid-related diseases |
| CA2900876A1 (en) * | 2004-12-22 | 2006-08-17 | Bhi Limited Partnership | Methods and compositions for treating amyloid-related diseases |
| TW200716088A (en) * | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
| US7420071B2 (en) * | 2005-05-04 | 2008-09-02 | Uchicago Argonne, Llc | Thermally stable surfactants and compositions and methods of use thereof |
| CA2628703C (en) | 2005-11-30 | 2019-10-29 | Abbott Laboratories | Anti-a.beta. globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies |
| EP1976877B2 (en) | 2005-11-30 | 2016-10-05 | AbbVie Inc. | Monoclonal antibodies against amyloid beta protein and uses thereof |
| AU2006326284B2 (en) | 2005-12-12 | 2013-06-06 | Ac Immune S.A. | A beta 1-42 specific monoclonal antibodies with therapeutic properties |
| SG172617A1 (en) | 2005-12-12 | 2011-07-28 | Ac Immune Sa | Therapeutic vaccine |
| BRPI0620637A2 (pt) | 2005-12-22 | 2011-11-16 | Neurochem Int Ltd | uso de compostos na preparação de medicamentos para a prevenção ou o tratamento de nefropatia diabética, complicação de desordem renal e dislipidemia, redução dos nìveis de lipìdeos e ácido úrico no soro, e aumento do clearance de creatinina e da função renal |
| WO2007084818A2 (en) * | 2006-01-10 | 2007-07-26 | Pipex, Inc. | Pharmaceutical compositions and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases |
| MY165105A (en) | 2006-07-14 | 2018-02-28 | Ac Immune Sa | Humanized antibody against amyloid beta |
| TWI551607B (zh) | 2006-07-14 | 2016-10-01 | Ac免疫公司 | 人類化抗體 |
| PL3851447T3 (pl) | 2006-10-12 | 2024-03-04 | Bellus Health Inc. | Sposoby, związki, kompozycje i nośniki dostarczające kwas 3-amino-1-propanosulfonowy |
| US8188046B2 (en) | 2006-10-16 | 2012-05-29 | University Of South Florida | Amyloid beta peptides and methods of use |
| BRPI0719379A2 (pt) | 2006-11-24 | 2014-02-11 | Ac Immune Sa | Composto, composição farmacêutica, uso de composto, mistura, métodos para coletar dados para o diagnóstico de uma doença ou condição associada com amilóide em uma amostra ou um paciente, para determinar a extensão da carga de placa amiloidogênica em um tecido e/ou um fluido corporal, para coletar dados para determinar a predisposição a uma doença ou condição associada com amilóide em um paciente, para coletar dados para monitorar a doença residual mínima em um paciente seguindo o tratamento com um anticorpo ou uma composição de vacina e para coletar dados para predizer a responsividade de um paciente sendo tratado com um anticorpo ou uma composição de vacina, e, kit de teste |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| GB0701970D0 (en) | 2007-02-01 | 2007-03-14 | Wilson Stuart | Treatment of protein aggregation diseases |
| EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| WO2008106657A2 (en) * | 2007-03-01 | 2008-09-04 | Intezyne Technologies, Inc. | Encapsulated amyloid-beta peptides |
| EP2160352A2 (en) * | 2007-05-24 | 2010-03-10 | Simone Arca | Method for the production of binary clathrate hydrates of hydrogen |
| EP2170389B1 (en) | 2007-06-12 | 2014-10-29 | AC Immune S.A. | Humanized antibodies to amyloid beta |
| TWI453217B (zh) | 2007-06-12 | 2014-09-21 | Ac Immune Sa | 抗β類澱粉蛋白單株抗體 |
| US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| CN101801406B (zh) * | 2007-07-20 | 2014-04-23 | 代阿麦迪卡股份有限公司 | 用于治疗淀粉样蛋白相关疾病的组织激肽释放酶 |
| EP2044951A1 (en) | 2007-10-02 | 2009-04-08 | Merz Pharma GmbH & Co. KGaA | The use of substances for the treatment of loss of eyesight in humans with glaucoma and other degenerative eye diseases |
| EP2650308A3 (en) | 2007-10-05 | 2014-11-12 | Genentech, Inc. | Use of anti-amyloid beta antibody in ocular diseases |
| SG10201505369QA (en) | 2007-10-05 | 2015-08-28 | Genentech Inc | Use of anti-amyloid beta antibody in ocular diseases |
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| UA107571C2 (xx) | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
| JP5051274B2 (ja) | 2009-06-04 | 2012-10-17 | 住友化学株式会社 | 加硫ゴムが有する粘弾性特性を改善させるためのs−(3−アミノプロピル)チオ硫酸および/またはその金属塩の使用 |
| EP2311823A1 (en) | 2009-10-15 | 2011-04-20 | AC Immune S.A. | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
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| EA200501023A1 (ru) | 2005-12-29 |
| EP1581203A1 (en) | 2005-10-05 |
| EA012325B1 (ru) | 2009-08-28 |
| US20060135403A1 (en) | 2006-06-22 |
| BR0317747A (pt) | 2005-11-22 |
| AU2003291910A1 (en) | 2004-07-22 |
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