NO20051089L - Bredspektrede 2-amino-benzotiazol-sulfonamid-HIV-proteaseinhibitorer - Google Patents
Bredspektrede 2-amino-benzotiazol-sulfonamid-HIV-proteaseinhibitorerInfo
- Publication number
- NO20051089L NO20051089L NO20051089A NO20051089A NO20051089L NO 20051089 L NO20051089 L NO 20051089L NO 20051089 A NO20051089 A NO 20051089A NO 20051089 A NO20051089 A NO 20051089A NO 20051089 L NO20051089 L NO 20051089L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- amino
- hiv protease
- benzothiazole
- spectrum
- Prior art date
Links
- XFMNXQKCYJXARU-UHFFFAOYSA-N 2-amino-3h-1,3-benzothiazole-2-sulfonamide Chemical compound C1=CC=C2SC(N)(S(N)(=O)=O)NC2=C1 XFMNXQKCYJXARU-UHFFFAOYSA-N 0.000 title 1
- 239000004030 hiv protease inhibitor Substances 0.000 title 1
- 238000001228 spectrum Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 108010010369 HIV Protease Proteins 0.000 abstract 2
- -1 hexahydrofuro [2,3-b] furanyl Chemical group 0.000 abstract 2
- UHGULLIUJBCTEF-UHFFFAOYSA-N 2-aminobenzothiazole Chemical class C1=CC=C2SC(N)=NC2=C1 UHGULLIUJBCTEF-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002971 oxazolyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 abstract 1
- 125000000335 thiazolyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- AIDS & HIV (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02078231 | 2002-08-02 | ||
| US42786202P | 2002-11-20 | 2002-11-20 | |
| PCT/EP2003/050359 WO2004014371A1 (fr) | 2002-08-02 | 2003-08-04 | Inhibiteurs broadspectrum 2-amino-benzothiazole sulfonamide hiv protease inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20051089L true NO20051089L (no) | 2005-05-02 |
Family
ID=31716850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20051089A NO20051089L (no) | 2002-08-02 | 2005-03-01 | Bredspektrede 2-amino-benzotiazol-sulfonamid-HIV-proteaseinhibitorer |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20050267156A1 (fr) |
| EP (1) | EP1545518A1 (fr) |
| KR (1) | KR20050025647A (fr) |
| CN (1) | CN1671380B (fr) |
| AP (1) | AP1878A (fr) |
| AU (1) | AU2003262561B2 (fr) |
| BR (1) | BR0305717A (fr) |
| CA (1) | CA2492832C (fr) |
| EA (1) | EA008594B1 (fr) |
| HR (1) | HRP20050605A2 (fr) |
| IL (1) | IL166257A (fr) |
| MX (1) | MXPA05001275A (fr) |
| NO (1) | NO20051089L (fr) |
| NZ (1) | NZ538488A (fr) |
| PL (1) | PL374948A1 (fr) |
| WO (1) | WO2004014371A1 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005244121B2 (en) * | 2004-05-07 | 2012-01-19 | Sequoia Pharmaceuticals, Inc. | Resistance-repellent retroviral protease inhibitors |
| JO2841B1 (en) * | 2006-06-23 | 2014-09-15 | تيبوتيك فارماسيوتيكالز ليمتد | 2-(substituted-amino) -benzothiazole sulfonamide as protease inhibitors HIV (HIV) |
| US8267163B2 (en) * | 2008-03-17 | 2012-09-18 | Visteon Global Technologies, Inc. | Radiator tube dimple pattern |
| WO2011061590A1 (fr) | 2009-11-17 | 2011-05-26 | Hetero Research Foundation | Nouveaux dérivés carboxamides comme inhibiteurs du vih |
| AP2013006707A0 (en) | 2010-07-02 | 2013-02-28 | Gilead Sciences Inc | 2-Quinolinyl-acetic acid derivatives as HIV antiviral compounds |
| TWI453208B (zh) | 2010-07-02 | 2014-09-21 | Gilead Sciences Inc | 治療性化合物類 |
| US9024038B2 (en) | 2010-12-27 | 2015-05-05 | Purdue Research Foundation | Compunds and methods for treating HIV |
| EP3181555B1 (fr) * | 2011-04-21 | 2018-11-28 | Gilead Sciences, Inc. | Composés de benzothiazole et leur utilisation pharmaceutique |
| WO2013103724A1 (fr) | 2012-01-04 | 2013-07-11 | Gilead Sciences, Inc. | Dérivés d'acide 2-(tert-butoxy)-2-(7-méthylquinoléin-6-yl)acétique pour traiter le sida |
| WO2013103738A1 (fr) | 2012-01-04 | 2013-07-11 | Gilead Sciences, Inc. | Dérivés d'acide naphtalène acétique contre l'infection par le vih |
| ES2571479T3 (es) | 2012-04-20 | 2016-05-25 | Gilead Sciences Inc | Derivados del ácido benzotiazol-6-il acético y su uso para tratar una infección por VIH |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968942A (en) * | 1992-08-25 | 1999-10-19 | G. D. Searle & Co. | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors |
| DK0715618T3 (da) * | 1993-08-24 | 1999-08-23 | Searle & Co | Hydroxyethylaminosulfonamider til anvendelse som inhibitorer af retrovirale proteaser |
| WO1999067254A2 (fr) * | 1998-06-23 | 1999-12-29 | The United States Of America Represented By The Secretary, Department Of Health And Human Services | Inhibiteurs de protease retrovirale resistant a l'action de plusieurs medicaments et procedes associes |
| PT1370543E (pt) * | 2001-02-14 | 2007-02-28 | Tibotec Pharm Ltd | Inibidores de protease de vih 2-(amino-substituída)-benzotiazol-sulfonamida de largo espectro |
-
2003
- 2003-08-04 PL PL03374948A patent/PL374948A1/xx not_active Application Discontinuation
- 2003-08-04 CN CN038184044A patent/CN1671380B/zh not_active Expired - Fee Related
- 2003-08-04 AP AP2005003242A patent/AP1878A/xx active
- 2003-08-04 HR HR20050605A patent/HRP20050605A2/hr not_active Application Discontinuation
- 2003-08-04 WO PCT/EP2003/050359 patent/WO2004014371A1/fr not_active Ceased
- 2003-08-04 CA CA2492832A patent/CA2492832C/fr not_active Expired - Fee Related
- 2003-08-04 NZ NZ538488A patent/NZ538488A/en not_active IP Right Cessation
- 2003-08-04 EP EP03784205A patent/EP1545518A1/fr not_active Ceased
- 2003-08-04 EA EA200500298A patent/EA008594B1/ru not_active IP Right Cessation
- 2003-08-04 US US10/523,445 patent/US20050267156A1/en not_active Abandoned
- 2003-08-04 MX MXPA05001275A patent/MXPA05001275A/es active IP Right Grant
- 2003-08-04 BR BR0305717-8A patent/BR0305717A/pt not_active Application Discontinuation
- 2003-08-04 AU AU2003262561A patent/AU2003262561B2/en not_active Ceased
- 2003-08-04 KR KR1020057001206A patent/KR20050025647A/ko not_active Ceased
-
2005
- 2005-01-12 IL IL166257A patent/IL166257A/en not_active IP Right Cessation
- 2005-03-01 NO NO20051089A patent/NO20051089L/no not_active Application Discontinuation
-
2009
- 2009-04-20 US US12/426,730 patent/US20090203742A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003262561B2 (en) | 2008-10-16 |
| CA2492832C (fr) | 2012-05-22 |
| MXPA05001275A (es) | 2005-04-28 |
| US20050267156A1 (en) | 2005-12-01 |
| IL166257A0 (en) | 2006-01-15 |
| EA200500298A1 (ru) | 2005-08-25 |
| EA008594B1 (ru) | 2007-06-29 |
| EP1545518A1 (fr) | 2005-06-29 |
| BR0305717A (pt) | 2004-09-28 |
| CN1671380A (zh) | 2005-09-21 |
| US20090203742A1 (en) | 2009-08-13 |
| WO2004014371A1 (fr) | 2004-02-19 |
| KR20050025647A (ko) | 2005-03-14 |
| CN1671380B (zh) | 2010-05-26 |
| PL374948A1 (en) | 2005-11-14 |
| IL166257A (en) | 2013-04-30 |
| AU2003262561A1 (en) | 2004-02-25 |
| AP1878A (en) | 2008-08-13 |
| NZ538488A (en) | 2007-10-26 |
| HRP20050605A2 (en) | 2006-02-28 |
| CA2492832A1 (fr) | 2004-02-19 |
| AP2005003242A0 (en) | 2005-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |