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NO20043295L - Faste salt-benzazepinforbindelser og deres anvendelse ved fremstilling av farmasoytiske forbindelser - Google Patents

Faste salt-benzazepinforbindelser og deres anvendelse ved fremstilling av farmasoytiske forbindelser

Info

Publication number
NO20043295L
NO20043295L NO20043295A NO20043295A NO20043295L NO 20043295 L NO20043295 L NO 20043295L NO 20043295 A NO20043295 A NO 20043295A NO 20043295 A NO20043295 A NO 20043295A NO 20043295 L NO20043295 L NO 20043295L
Authority
NO
Norway
Prior art keywords
compounds
preparation
solid salt
benzazepine
pharmaceutical
Prior art date
Application number
NO20043295A
Other languages
English (en)
Other versions
NO330528B1 (no
Inventor
Paulus Franciscus Corneli Meij
Joris A Van Der Eerden
Paulus Pg De Jong
Original Assignee
Solvay Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Publication of NO20043295L publication Critical patent/NO20043295L/no
Publication of NO330528B1 publication Critical patent/NO330528B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20043295A 2002-01-16 2004-08-06 Nye salter av benzazepinforbindelser, fremgangsmater for fremstilling derav, og anvendelse av slike i farmasoytiske sammensetninger NO330528B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02075621 2002-01-16
NL1019762 2002-01-17
PCT/EP2003/000515 WO2003059939A1 (en) 2002-01-16 2003-01-15 Solid salts benzazepine compounds and their use in the preparation of pharmaceuticals compounds

Publications (2)

Publication Number Publication Date
NO20043295L true NO20043295L (no) 2004-08-06
NO330528B1 NO330528B1 (no) 2011-05-09

Family

ID=26077601

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043295A NO330528B1 (no) 2002-01-16 2004-08-06 Nye salter av benzazepinforbindelser, fremgangsmater for fremstilling derav, og anvendelse av slike i farmasoytiske sammensetninger

Country Status (15)

Country Link
US (1) US6998398B2 (no)
EP (1) EP1468010A1 (no)
JP (1) JP4384495B2 (no)
KR (1) KR100979077B1 (no)
CN (1) CN100591689C (no)
AU (1) AU2003206755B2 (no)
BR (1) BR0306701A (no)
CA (1) CA2473447A1 (no)
HR (1) HRP20040560A2 (no)
IL (1) IL162645A0 (no)
MX (1) MXPA04006887A (no)
NO (1) NO330528B1 (no)
PL (1) PL371511A1 (no)
RU (1) RU2303041C2 (no)
WO (1) WO2003059939A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050009031A (ko) * 2003-07-15 2005-01-24 엘지전자 주식회사 1회 기록 가능한 광디스크 및 광디스크의 관리정보 기록방법
SA04250283B1 (ar) * 2003-09-26 2008-05-26 سولفاي فارماسيتيكالز جي أم بي أتش مشتقات من amidomethy1-substituted1-(carboxyalkyl)-cyclopentylcarbonylamino-benzazepine-N-acetic acid
PL1687006T3 (pl) 2003-11-18 2008-01-31 Solvay Pharm Gmbh Kompozycje farmaceutyczne do leczenia zaburzeń czynności nerek
US20050267124A1 (en) * 2004-05-14 2005-12-01 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous producing system and PDEV inhibiitors
JP2008524159A (ja) 2004-12-15 2008-07-10 ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング NEP阻害剤、内因性エンドセリン産生系の阻害剤およびHMGCoAレダクターゼ阻害剤を含有する医薬組成物
US20060159748A1 (en) * 2004-12-23 2006-07-20 Rajesh Jain Oral immediate release formulation of a poorly water-soluble active substance
US20060205625A1 (en) * 2005-02-18 2006-09-14 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and diuretics
WO2007054975A1 (en) * 2005-11-08 2007-05-18 Panacea Biotec Ltd Pharmaceutical compositions for the treatment of cardiovascular and other associated disorders
HU227696B1 (en) * 2006-04-13 2011-12-28 Egyt Gyogyszervegyeszeti Gyar Zinc salt of rosuvastatin, process for its preparation and pharmaceutical compositions containing it
PL424452A1 (pl) 2018-01-31 2019-08-12 Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP) do profilaktyki i leczenia chorób oczu
PL424453A1 (pl) 2018-01-31 2019-08-12 Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością Sposoby zmniejszania szkodliwego działania niedoboru perfuzji narządów miąższowych przez inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19510566A1 (de) * 1995-03-23 1996-09-26 Kali Chemie Pharma Gmbh Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19638020A1 (de) * 1996-09-18 1998-03-19 Solvay Pharm Gmbh Die gastrointestinale Durchblutung fördernde Arzneimittel
DE19750002A1 (de) * 1997-11-12 1999-05-20 Solvay Pharm Gmbh Phosphonsäure-substituierte Benzazepinon-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19906310A1 (de) * 1999-02-16 2000-08-17 Solvay Pharm Gmbh Arzneimittel zur Behandlung von Bluthochdruck
DE19932555A1 (de) * 1999-07-13 2001-01-18 Solvay Pharm Gmbh Arzneimittel mit protektiver Wirkung gegen oxidativ-toxische und insbesondere gegen kardiotoxische Substanzen

Also Published As

Publication number Publication date
CN1617883A (zh) 2005-05-18
KR100979077B1 (ko) 2010-08-31
HK1072946A1 (zh) 2005-09-16
RU2303041C2 (ru) 2007-07-20
JP2005520809A (ja) 2005-07-14
AU2003206755A1 (en) 2003-07-30
MXPA04006887A (es) 2004-12-06
CA2473447A1 (en) 2003-07-24
US6998398B2 (en) 2006-02-14
AU2003206755B2 (en) 2008-07-17
RU2004124840A (ru) 2006-01-20
NO330528B1 (no) 2011-05-09
JP4384495B2 (ja) 2009-12-16
CN100591689C (zh) 2010-02-24
WO2003059939A1 (en) 2003-07-24
HRP20040560A2 (en) 2004-10-31
EP1468010A1 (en) 2004-10-20
US20050038012A1 (en) 2005-02-17
BR0306701A (pt) 2004-12-28
IL162645A0 (en) 2005-11-20
KR20040089106A (ko) 2004-10-20
PL371511A1 (en) 2005-06-27

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