NO20043840L - Microglia Inhibitors for Stopping Immune Reactions Induced by Interleukin-12 and IFN-Gamma - Google Patents

Microglia Inhibitors for Stopping Immune Reactions Induced by Interleukin-12 and IFN-Gamma

Info

Publication number: NO20043840L
Authority: NO; Norway
Prior art keywords: ifn; interleukin; gamma; stopping; immune reactions
Prior art date: 2002-02-15

Application number

NO20043840A

Other languages

Norwegian (no)

Inventor

Herbert Schneider

Wolfgang Halfbrodt

Thorsten Blume

Joachim Kuhnke

Ursula Monning

Wolf-Dietrich Doche

Bernd Elger

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-15

Filing date

2004-09-14

Publication date

2004-11-12

2004-09-14 Application filed by Schering Ag filed Critical Schering Ag

2004-11-12 Publication of NO20043840L publication Critical patent/NO20043840L/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Hematology (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Transplantation (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

NO20043840A 2002-02-15 2004-09-14 Microglia Inhibitors for Stopping Immune Reactions Induced by Interleukin-12 and IFN-Gamma NO20043840L (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10207843A DE10207843A1 (en)	2002-02-15	2002-02-15	Microlia inhibitors for interruption of interleukin 12 and IFN-gamma mediated immune responses
PCT/EP2003/000467 WO2003068225A1 (en)	2002-02-15	2003-01-17	Microglia inhibitors for interrupting immune reactions induced by interleukin 12 and ifn$g(g)

Publications (1)

Publication Number	Publication Date
NO20043840L true NO20043840L (en)	2004-11-12

Family

ID=27674912

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20043840A NO20043840L (en)	2002-02-15	2004-09-14	Microglia Inhibitors for Stopping Immune Reactions Induced by Interleukin-12 and IFN-Gamma

Country Status (21)

Country	Link
EP (1)	EP1474138A1 (en)
JP (1)	JP2005522447A (en)
KR (1)	KR20040084909A (en)
CN (1)	CN1756546A (en)
AR (1)	AR039556A1 (en)
AU (1)	AU2003245523A1 (en)
BR (1)	BR0307706A (en)
CA (1)	CA2475770A1 (en)
DE (1)	DE10207843A1 (en)
EC (1)	ECSP045297A (en)
MX (1)	MXPA04007943A (en)
NO (1)	NO20043840L (en)
PE (1)	PE20030906A1 (en)
PL (1)	PL371327A1 (en)
RS (1)	RS71304A (en)
RU (1)	RU2004127677A (en)
TW (1)	TW200306823A (en)
UA (1)	UA81111C2 (en)
UY (1)	UY27662A1 (en)
WO (1)	WO2003068225A1 (en)
ZA (1)	ZA200407382B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10207844A1 (en) *	2002-02-15	2003-09-04	Schering Ag	1-phenyl-2-heteroaryl-substituted benzimidazole derivatives, their use for the preparation of medicaments and pharmaceutical preparations containing these derivatives
DE602005016729D1 (en) *	2005-03-17	2009-10-29	Proyecto Biomedicina Cima Sl	USE OF 5'-METHYLTHIOADENOSINE FOR THE PREVENTION AND / OR TREATMENT OF AUTOIMMUNE DISEASES AND / OR TRANSPLANT DISPOSAL
WO2013186229A1 (en) *	2012-06-11	2013-12-19	Ucb Pharma S.A.	Tnf -alpha modulating benzimidazoles
US9586949B2 (en)	2015-02-09	2017-03-07	Incyte Corporation	Aza-heteroaryl compounds as PI3K-gamma inhibitors
LT3371190T (en)	2015-11-06	2022-08-10	Incyte Corporation	HETEROCYCLIC COMPOUNDS AS PI3K-GAMA INHIBITORS
DK3390367T3 (en) *	2015-12-15	2020-10-26	Univ Leland Stanford Junior	Method for the prevention and / or treatment of age-related cognitive impairment and neuroinflammation
AR107293A1 (en)	2016-01-05	2018-04-18	Incyte Corp	PIRIDINE AND PYRIDIMINE COMPOUNDS AS PI3K-g INHIBITORS
US10138248B2 (en)	2016-06-24	2018-11-27	Incyte Corporation	Substituted imidazo[2,1-f][1,2,4]triazines, substituted imidazo[1,2-a]pyridines, substituted imidazo[1,2-b]pyridazines and substituted imidazo[1,2-a]pyrazines as PI3K-γ inhibitors
WO2019079469A1 (en)	2017-10-18	2019-04-25	Incyte Corporation	Condensed imidazole derivatives substituted by tertiary hydroxy groups as pi3k-gamma inhibitors
CR20250050A (en)	2018-09-05	2025-03-19	Incyte Corp	Crystalline forms of a phosphoinositide 3-kinase (pi3k) inhibitor
PL3860998T3 (en)	2018-10-05	2024-06-17	Annapurna Bio Inc.	Compounds and compositions for treating conditions associated with apj receptor activity
CN112341450B (en) *	2019-08-09	2022-05-17	成都先导药物开发股份有限公司	Immunomodulator
CN112341451B (en) *	2019-08-09	2022-06-17	成都先导药物开发股份有限公司	Immunomodulator
WO2021126923A1 (en) *	2019-12-19	2021-06-24	The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services	Cd206 modulators their use and methods for preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4330959A1 (en) *	1993-09-09	1995-03-16	Schering Ag	New benzimidazole derivatives, processes for their preparation and their pharmaceutical use
CA2396227C (en) *	2000-01-14	2012-03-20	Schering Aktiengesellschaft	1,2-diaryl benzimidazoles for treating illnesses associated with a microglia activation
DE10134775A1 (en) *	2001-07-06	2003-01-30	Schering Ag	1-alkyl-2.aryl-benzimidazole derivatives, their use for the manufacture of medicaments and pharmaceutical preparations containing these derivatives
DE10135050A1 (en) *	2001-07-09	2003-02-06	Schering Ag	1-Ary1-2-N-, S- or O-substituted benzimidazole derivatives, their use for the preparation of medicaments and pharmaceutical preparations containing them

2002
- 2002-02-15 DE DE10207843A patent/DE10207843A1/en not_active Ceased
2003
- 2003-01-17 KR KR10-2004-7012557A patent/KR20040084909A/en not_active Ceased
- 2003-01-17 UA UA20040907401A patent/UA81111C2/en unknown
- 2003-01-17 CN CNA038039923A patent/CN1756546A/en active Pending
- 2003-01-17 RS YU71304A patent/RS71304A/en unknown
- 2003-01-17 CA CA002475770A patent/CA2475770A1/en not_active Abandoned
- 2003-01-17 PL PL03371327A patent/PL371327A1/en not_active Application Discontinuation
- 2003-01-17 WO PCT/EP2003/000467 patent/WO2003068225A1/en not_active Ceased
- 2003-01-17 RU RU2004127677/15A patent/RU2004127677A/en unknown
- 2003-01-17 BR BR0307706-3A patent/BR0307706A/en not_active IP Right Cessation
- 2003-01-17 EP EP03739380A patent/EP1474138A1/en not_active Withdrawn
- 2003-01-17 JP JP2003567407A patent/JP2005522447A/en active Pending
- 2003-01-17 AU AU2003245523A patent/AU2003245523A1/en not_active Abandoned
- 2003-01-17 MX MXPA04007943A patent/MXPA04007943A/en unknown
- 2003-02-03 PE PE2003000119A patent/PE20030906A1/en not_active Application Discontinuation
- 2003-02-11 UY UY27662A patent/UY27662A1/en not_active Application Discontinuation
- 2003-02-12 AR ARP030100436A patent/AR039556A1/en unknown
- 2003-02-14 TW TW092103072A patent/TW200306823A/en unknown
2004
- 2004-09-14 EC EC2004005297A patent/ECSP045297A/en unknown
- 2004-09-14 ZA ZA200407382A patent/ZA200407382B/en unknown
- 2004-09-14 NO NO20043840A patent/NO20043840L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2475770A1 (en)	2003-08-21
PL371327A1 (en)	2005-06-13
UY27662A1 (en)	2003-09-30
WO2003068225A1 (en)	2003-08-21
ECSP045297A (en)	2004-10-26
KR20040084909A (en)	2004-10-06
BR0307706A (en)	2005-01-11
AU2003245523A1 (en)	2003-09-04
ZA200407382B (en)	2005-09-14
CN1756546A (en)	2006-04-05
AR039556A1 (en)	2005-02-23
RU2004127677A (en)	2005-06-10
UA81111C2 (en)	2007-12-10
EP1474138A1 (en)	2004-11-10
DE10207843A1 (en)	2003-09-04
JP2005522447A (en)	2005-07-28
PE20030906A1 (en)	2004-01-17
TW200306823A (en)	2003-12-01
RS71304A (en)	2006-10-27
MXPA04007943A (en)	2004-11-26

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Legal Events

Date	Code	Title	Description
2009-08-31	FC2A	Withdrawal, rejection or dismissal of laid open patent application