NO20040210L - Fenylacetamido-tiazolderivater, fremgangsmate for deres fremstilling og deres anvendelse som antitumormidler - Google Patents
Fenylacetamido-tiazolderivater, fremgangsmate for deres fremstilling og deres anvendelse som antitumormidlerInfo
- Publication number
- NO20040210L NO20040210L NO20040210A NO20040210A NO20040210L NO 20040210 L NO20040210 L NO 20040210L NO 20040210 A NO20040210 A NO 20040210A NO 20040210 A NO20040210 A NO 20040210A NO 20040210 L NO20040210 L NO 20040210L
- Authority
- NO
- Norway
- Prior art keywords
- phenylacetamido
- preparation
- antitumor agents
- thiazole derivatives
- thiazole
- Prior art date
Links
- HYRZQLIFVQELLP-UHFFFAOYSA-N 2-phenyl-n-(1,3-thiazol-2-yl)acetamide Chemical class N=1C=CSC=1NC(=O)CC1=CC=CC=C1 HYRZQLIFVQELLP-UHFFFAOYSA-N 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90794701A | 2001-07-19 | 2001-07-19 | |
| US35764202P | 2002-02-20 | 2002-02-20 | |
| PCT/EP2002/007289 WO2003008365A2 (en) | 2001-07-19 | 2002-07-02 | Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20040210L true NO20040210L (no) | 2004-03-03 |
Family
ID=26999733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20040210A NO20040210L (no) | 2001-07-19 | 2004-01-16 | Fenylacetamido-tiazolderivater, fremgangsmate for deres fremstilling og deres anvendelse som antitumormidler |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20040235919A1 (no) |
| EP (1) | EP1406899B1 (no) |
| JP (1) | JP2004534857A (no) |
| KR (1) | KR100908794B1 (no) |
| CN (1) | CN1286835C (no) |
| AR (1) | AR036176A1 (no) |
| AT (1) | ATE345341T1 (no) |
| AU (1) | AU2002325860B2 (no) |
| BR (1) | BR0211265A (no) |
| CA (1) | CA2453294A1 (no) |
| CY (1) | CY1105948T1 (no) |
| CZ (1) | CZ2004107A3 (no) |
| DE (1) | DE60216097T2 (no) |
| DK (1) | DK1406899T3 (no) |
| EA (1) | EA007392B1 (no) |
| ES (1) | ES2274076T3 (no) |
| GE (1) | GEP20105095B (no) |
| IL (2) | IL159570A0 (no) |
| MX (1) | MXPA04000407A (no) |
| NO (1) | NO20040210L (no) |
| NZ (1) | NZ530524A (no) |
| PL (1) | PL367938A1 (no) |
| PT (1) | PT1406899E (no) |
| WO (1) | WO2003008365A2 (no) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7572914B2 (en) | 2003-12-19 | 2009-08-11 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| RU2383542C2 (ru) * | 2004-08-17 | 2010-03-10 | Ф.Хоффманн-Ля Рош Аг | Замещенные гидантоины |
| US7550598B2 (en) | 2004-08-18 | 2009-06-23 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| TW200621766A (en) * | 2004-09-17 | 2006-07-01 | Hoffmann La Roche | Substituted hydantoins |
| EP1812439B2 (en) | 2004-10-15 | 2017-12-06 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| BRPI0719883A2 (pt) | 2006-10-09 | 2015-05-05 | Takeda Pharmaceutical | Inibidores de quinase |
| US8168794B2 (en) | 2008-03-03 | 2012-05-01 | Novartis Ag | Pim kinase inhibitors and methods of their use |
| EA026432B1 (ru) | 2012-05-21 | 2017-04-28 | Новартис Аг | Новые замещенные в цикле n-пиридиниламиды в качестве ингибиторов киназ |
| EP2925750A1 (en) | 2012-11-29 | 2015-10-07 | Karyopharm Therapeutics, Inc. | Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof |
| AU2014285019C1 (en) | 2013-07-03 | 2019-05-02 | Karyopharm Therapeutics Inc. | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof |
| WO2015042414A1 (en) * | 2013-09-20 | 2015-03-26 | Karyopharm Therapeutics Inc. | Multicyclic compounds and methods of using same |
| MX2018001979A (es) | 2015-08-18 | 2019-04-25 | Karyopharm Therapeutics Inc | (s,e) -3- (6-aminopiridin-3-il) -n- ( (5- (4- (3-fluoruro-3 metilpirrolidin-1-carbonil) fenil) -7- (4 fluorofenil) benzofuran-2-il)metil)acrilamida para el tratamiento del cancer. |
| WO2017117447A1 (en) | 2015-12-31 | 2017-07-06 | Karyopharm Therapeutics Inc. | Multicyclic compounds and uses thereof |
| SG11202100531RA (en) | 2018-09-17 | 2021-02-25 | Yungjin Pharm Co Ltd | Novel thiazole derivatives and pharmaceutically acceptable salts thereof |
| KR102335637B1 (ko) * | 2020-03-13 | 2021-12-06 | 영진약품 주식회사 | 신규한 cdk7 억제 화합물 및 이의 약제학적으로 허용가능한 염 |
| CN112979634A (zh) * | 2021-02-06 | 2021-06-18 | 绍兴文理学院 | 一种含酰胺结构的噻唑类化合物及其制备方法和应用 |
| CN112979636A (zh) * | 2021-02-06 | 2021-06-18 | 绍兴文理学院 | 一种含苯硫醚结构的噻唑类化合物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6040321A (en) * | 1997-11-12 | 2000-03-21 | Bristol-Myers Squibb Company | Aminothiazole inhibitors of cyclin dependent kinases |
| US6214852B1 (en) * | 1998-10-21 | 2001-04-10 | Bristol-Myers Squibb Company | N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]-carboxamide inhibitors of cyclin dependent kinases |
| GB9823871D0 (en) * | 1998-10-30 | 1998-12-23 | Pharmacia & Upjohn Spa | 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents |
| US6114365A (en) * | 1999-08-12 | 2000-09-05 | Pharmacia & Upjohn S.P.A. | Arylmethyl-carbonylamino-thiazole derivatives, process for their preparation, and their use as antitumor agents |
-
2002
- 2002-07-02 PL PL02367938A patent/PL367938A1/xx not_active Application Discontinuation
- 2002-07-02 DK DK02760213T patent/DK1406899T3/da active
- 2002-07-02 WO PCT/EP2002/007289 patent/WO2003008365A2/en not_active Ceased
- 2002-07-02 BR BR0211265-5A patent/BR0211265A/pt not_active IP Right Cessation
- 2002-07-02 CZ CZ2004107A patent/CZ2004107A3/cs unknown
- 2002-07-02 CN CNB028143388A patent/CN1286835C/zh not_active Expired - Fee Related
- 2002-07-02 ES ES02760213T patent/ES2274076T3/es not_active Expired - Lifetime
- 2002-07-02 GE GEAP200911511A patent/GEP20105095B/en unknown
- 2002-07-02 AT AT02760213T patent/ATE345341T1/de not_active IP Right Cessation
- 2002-07-02 EP EP02760213A patent/EP1406899B1/en not_active Expired - Lifetime
- 2002-07-02 EA EA200400208A patent/EA007392B1/ru not_active IP Right Cessation
- 2002-07-02 DE DE60216097T patent/DE60216097T2/de not_active Expired - Lifetime
- 2002-07-02 IL IL15957002A patent/IL159570A0/xx not_active IP Right Cessation
- 2002-07-02 US US10/483,620 patent/US20040235919A1/en not_active Abandoned
- 2002-07-02 MX MXPA04000407A patent/MXPA04000407A/es active IP Right Grant
- 2002-07-02 PT PT02760213T patent/PT1406899E/pt unknown
- 2002-07-02 AU AU2002325860A patent/AU2002325860B2/en not_active Ceased
- 2002-07-02 NZ NZ530524A patent/NZ530524A/en not_active IP Right Cessation
- 2002-07-02 KR KR1020047000859A patent/KR100908794B1/ko not_active Expired - Fee Related
- 2002-07-02 JP JP2003513926A patent/JP2004534857A/ja not_active Ceased
- 2002-07-02 CA CA002453294A patent/CA2453294A1/en not_active Abandoned
- 2002-07-18 AR ARP020102690A patent/AR036176A1/es unknown
-
2004
- 2004-01-16 NO NO20040210A patent/NO20040210L/no not_active Application Discontinuation
-
2007
- 2007-01-25 CY CY20071100090T patent/CY1105948T1/el unknown
-
2010
- 2010-04-08 IL IL204947A patent/IL204947A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1406899E (pt) | 2007-01-31 |
| NZ530524A (en) | 2006-12-22 |
| CA2453294A1 (en) | 2003-01-30 |
| GEP20105095B (en) | 2010-10-25 |
| HK1068336A1 (en) | 2005-04-29 |
| WO2003008365A3 (en) | 2004-02-12 |
| PL367938A1 (en) | 2005-03-07 |
| EP1406899B1 (en) | 2006-11-15 |
| AU2002325860B2 (en) | 2008-03-13 |
| CZ2004107A3 (cs) | 2004-04-14 |
| IL159570A0 (en) | 2004-06-01 |
| BR0211265A (pt) | 2004-07-20 |
| CY1105948T1 (el) | 2011-04-06 |
| JP2004534857A (ja) | 2004-11-18 |
| DE60216097T2 (de) | 2007-06-28 |
| DE60216097D1 (de) | 2006-12-28 |
| CN1286835C (zh) | 2006-11-29 |
| MXPA04000407A (es) | 2004-03-18 |
| KR20040030821A (ko) | 2004-04-09 |
| IL204947A0 (en) | 2010-11-30 |
| EA200400208A1 (ru) | 2004-06-24 |
| ATE345341T1 (de) | 2006-12-15 |
| EP1406899A2 (en) | 2004-04-14 |
| US20040235919A1 (en) | 2004-11-25 |
| DK1406899T3 (da) | 2007-04-02 |
| CN1531535A (zh) | 2004-09-22 |
| WO2003008365A2 (en) | 2003-01-30 |
| AR036176A1 (es) | 2004-08-18 |
| EA007392B1 (ru) | 2006-10-27 |
| KR100908794B1 (ko) | 2009-07-22 |
| ES2274076T3 (es) | 2007-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |