[go: up one dir, main page]

NO20031356L - Novel polymorphic forms of 5- [4- [2- [N-methyl-N- (2-pyridyl] amino] ethoxy] benzyl] thiazolidine-2,4-dione maleate and process for preparing the same - Google Patents

Novel polymorphic forms of 5- [4- [2- [N-methyl-N- (2-pyridyl] amino] ethoxy] benzyl] thiazolidine-2,4-dione maleate and process for preparing the same

Info

Publication number
NO20031356L
NO20031356L NO20031356A NO20031356A NO20031356L NO 20031356 L NO20031356 L NO 20031356L NO 20031356 A NO20031356 A NO 20031356A NO 20031356 A NO20031356 A NO 20031356A NO 20031356 L NO20031356 L NO 20031356L
Authority
NO
Norway
Prior art keywords
thiazolidine
pyridyl
ethoxy
benzyl
amino
Prior art date
Application number
NO20031356A
Other languages
Norwegian (no)
Other versions
NO20031356D0 (en
NO324968B1 (en
Inventor
Prabhakar Chebiyyam
Ramabhadra Sarma Mamillapalli
Vyas Krishnamurthi
Vishnuvardhan Reddy Seella
Om Reddy Gaddam
Original Assignee
Reddy Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reddy Research Foundation filed Critical Reddy Research Foundation
Publication of NO20031356D0 publication Critical patent/NO20031356D0/en
Publication of NO20031356L publication Critical patent/NO20031356L/en
Publication of NO324968B1 publication Critical patent/NO324968B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20031356A 2000-09-26 2003-03-25 Novel polymorphic forms of 5- [4- [2- [N-methyl-N- (2-pyridyl] amino] ethoxy] benzyl] thiazolidine-2,4-dione maleate, processes for preparing the same, uses thereof, and medicaments containing compounds NO324968B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN805CH2000 2000-09-26
PCT/US2001/029896 WO2002026737A1 (en) 2000-09-26 2001-09-25 Novel polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation

Publications (3)

Publication Number Publication Date
NO20031356D0 NO20031356D0 (en) 2003-03-25
NO20031356L true NO20031356L (en) 2003-05-26
NO324968B1 NO324968B1 (en) 2008-01-14

Family

ID=29266775

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20031356A NO324968B1 (en) 2000-09-26 2003-03-25 Novel polymorphic forms of 5- [4- [2- [N-methyl-N- (2-pyridyl] amino] ethoxy] benzyl] thiazolidine-2,4-dione maleate, processes for preparing the same, uses thereof, and medicaments containing compounds

Country Status (15)

Country Link
EP (1) EP1322647A1 (en)
JP (1) JP2004509961A (en)
AU (1) AU9123201A (en)
BR (1) BR0114196A (en)
CA (1) CA2426117A1 (en)
CZ (1) CZ2003864A3 (en)
HU (1) HUP0301161A3 (en)
IL (1) IL155036A0 (en)
MX (1) MXPA03002580A (en)
NO (1) NO324968B1 (en)
NZ (1) NZ525498A (en)
PL (1) PL360661A1 (en)
SK (1) SK3752003A3 (en)
WO (1) WO2002026737A1 (en)
ZA (1) ZA200303223B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6664278B2 (en) 1997-12-16 2003-12-16 Smithkline Beecham P.L.C. Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
US20020137940A1 (en) 1997-12-16 2002-09-26 Smithkline Beecham P.L.C. 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726563D0 (en) 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
YU75301A (en) 1999-04-23 2004-07-15 Smithkline Beecham P.L.C. Polymorph of 5-(4-(2-(n-methyl-n-(2-pyrridyl)aamino)ethoxy) benzyl)thiazolidine-2,4-dione
ATE247653T1 (en) 1999-04-23 2003-09-15 Smithkline Beecham Plc THIAZOLIDINEDIONE DERIVATIVE AND ITS USE AS AN ANTIDIABETIC DRUG
US20040248945A1 (en) 1999-04-23 2004-12-09 Smithkline Beecham P.L.C. Thiazolidinedione derivative and its use as antidiabetic
US7041691B1 (en) 1999-06-30 2006-05-09 Amgen Inc. Compounds for the modulation of PPARγ activity
US20030171399A1 (en) 2000-06-28 2003-09-11 Tularik Inc. Quinolinyl and benzothiazolyl modulators
WO2004062667A1 (en) * 2003-01-08 2004-07-29 Dr. Reddy's Laboratories Limited Amorphous form of rosiglitazone maleate and process for preparation thereof
GB0307259D0 (en) * 2003-03-28 2003-05-07 Glaxo Group Ltd Process
EP1468997A3 (en) * 2003-04-18 2004-11-03 CHEMI S.p.A. Polymorphous forms of rosiglitazone maleate
GB2405403A (en) * 2003-08-29 2005-03-02 Cipla Ltd Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
UA83504C2 (en) 2003-09-04 2008-07-25 Селджин Корпорейшн Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
US7223761B2 (en) 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
AR047541A1 (en) * 2004-02-13 2006-01-25 Sandoz Ag PHOSPHATE OF 5 - [[4- [2-METHYL-2-PYRIDINYL-AMINO-ETOXI] PHENYL] METHYL] -2,4 THYZOLIDINADION (ROSIGLITAZONE) AND ITS POLYMORPHIC FORMS
US20070225337A1 (en) * 2004-03-31 2007-09-27 Sandoz Ag Novel Co-Precipitate of Amorphous Rosiglitazone
WO2005108396A1 (en) * 2004-05-11 2005-11-17 Santen Pharmaceutical Co., Ltd. Therapeutic agent for keratoconjunctiva disorder
JP2005350451A (en) * 2004-05-11 2005-12-22 Santen Pharmaceut Co Ltd Agent for treating keratoconjunctival trouble
CZ2004844A3 (en) * 2004-07-27 2006-03-15 Zentiva, A. S Salt of oxalic acid with 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, process for its preparation and its use
ITMI20041537A1 (en) * 2004-07-28 2004-10-28 Chemi Spa NEW POLYMORPHIC SHAPE OF EVIL ROSIGLITAZONE
CZ298424B6 (en) * 2005-05-24 2007-09-26 Zentiva, A. S. Crystallization process of rosiglitazone and derivatives thereof from mixed solutions
EP2184055A1 (en) 2008-11-07 2010-05-12 LEK Pharmaceuticals d.d. Process for preparing solid dosage forms of rosiglitazone maleate

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE186724T1 (en) * 1987-09-04 1999-12-15 Beecham Group Plc SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVES
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
CN1196730A (en) * 1996-06-19 1998-10-21 雷迪博士研究基金会 New polymorphic forms of troglitazone with enhanced anti-diabetic activity and process for their preparation
JP2000514041A (en) * 1996-07-26 2000-10-24 ドクター・レディーズ・リサーチ・ファウンデーション Thiazolidinedione compounds having anti-diabetic, hypolipidemic and anti-hypertensive properties, their preparation, and their pharmaceutical compositions
GB9726566D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
ATE247653T1 (en) * 1999-04-23 2003-09-15 Smithkline Beecham Plc THIAZOLIDINEDIONE DERIVATIVE AND ITS USE AS AN ANTIDIABETIC DRUG
YU75301A (en) * 1999-04-23 2004-07-15 Smithkline Beecham P.L.C. Polymorph of 5-(4-(2-(n-methyl-n-(2-pyrridyl)aamino)ethoxy) benzyl)thiazolidine-2,4-dione

Also Published As

Publication number Publication date
HUP0301161A2 (en) 2003-11-28
IL155036A0 (en) 2003-10-31
NO20031356D0 (en) 2003-03-25
NZ525498A (en) 2004-11-26
ZA200303223B (en) 2004-07-26
EP1322647A1 (en) 2003-07-02
CA2426117A1 (en) 2002-04-04
MXPA03002580A (en) 2003-10-15
BR0114196A (en) 2003-07-22
AU9123201A (en) 2002-04-08
JP2004509961A (en) 2004-04-02
NO324968B1 (en) 2008-01-14
SK3752003A3 (en) 2005-03-04
WO2002026737A1 (en) 2002-04-04
WO2002026737A8 (en) 2003-11-06
HUP0301161A3 (en) 2005-04-28
CZ2003864A3 (en) 2004-01-14
PL360661A1 (en) 2004-09-20

Similar Documents

Publication Publication Date Title
NO20031356L (en) Novel polymorphic forms of 5- [4- [2- [N-methyl-N- (2-pyridyl] amino] ethoxy] benzyl] thiazolidine-2,4-dione maleate and process for preparing the same
NO20024307D0 (en) Hydrochloride salts of 5- [4- [2- (N-methyl-N- (2-pyridyl) amino) ethoxy] benzyl] thiazolidine-2,4-dione
MXPA01010821A (en) Polymorph of 5-[4-[2- (n-methyl-n-( 2-pyridyl)amino) ethoxy]benzyl] thiazolidine-2,4-dione, maleic acid salt.
NO20031020D0 (en) Hydrochloride salt of 5- [4- [2- (N-methyl-N- (2-pyridyl) amino) ethoxy] benzyl] thiazolidine-2,4-dione
DK1349855T3 (en) 5- (4- (2- (N-methyl-N- (2-pyridyl) amino) ethoxy) benzyl) thiazolidin-2,4-dionmesylatsalt
DE60212434D1 (en) ROSIGLITAZONE EDISYLATES AND THEIR USE AS ANTIDIABETICS
IL188116A0 (en) Sodium salts of 5-[4-[2-(n-methyl-n-(2-pyridyl) amino) ethoxy] benzyl] thiazolidine-2,4-dione
IL153280A0 (en) 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4 dione hydriodide as pharmaceutical
SI1265893T1 (en) Hydrochloride salts of 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione
HK1055294A (en) 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione hydriodide as pharmaceutical
SI1173435T1 (en) Polymorph of 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione maleic acid salt
HK1057209A (en) Novel polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino]ethoxy]benz yl]thiazolidine-2,4-dione maleic acid salt and process for their preparation
HK1059259A (en) Sodium salts of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
HK1068883A (en) 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione and pharmaceutical compositions comprising the same