NO20030128L - Treatment of B cell malignancy using combination of B cell-reducing antibody and immunomodulatory antibody related applications - Google Patents
Treatment of B cell malignancy using combination of B cell-reducing antibody and immunomodulatory antibody related applicationsInfo
- Publication number
- NO20030128L NO20030128L NO20030128A NO20030128A NO20030128L NO 20030128 L NO20030128 L NO 20030128L NO 20030128 A NO20030128 A NO 20030128A NO 20030128 A NO20030128 A NO 20030128A NO 20030128 L NO20030128 L NO 20030128L
- Authority
- NO
- Norway
- Prior art keywords
- cell
- antibody
- treatment
- combination
- related applications
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 210000003719 b-lymphocyte Anatomy 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 230000002519 immonomodulatory effect Effects 0.000 title 1
- 230000036210 malignancy Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21770600P | 2000-07-12 | 2000-07-12 | |
| US09/772,938 US20020006404A1 (en) | 1999-11-08 | 2001-01-31 | Treatment of cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications |
| PCT/US2001/015677 WO2002004021A1 (en) | 2000-07-12 | 2001-05-16 | Treatment of b cell malignancies using combination of b cell depleting antibody and immune modulating antibody related applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20030128D0 NO20030128D0 (en) | 2003-01-10 |
| NO20030128L true NO20030128L (en) | 2003-03-12 |
Family
ID=26912176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20030128A NO20030128L (en) | 2000-07-12 | 2003-01-10 | Treatment of B cell malignancy using combination of B cell-reducing antibody and immunomodulatory antibody related applications |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1305045A1 (en) |
| JP (1) | JP2004502742A (en) |
| KR (2) | KR20080039547A (en) |
| CN (1) | CN1446104A (en) |
| AU (2) | AU2001264612C1 (en) |
| CA (1) | CA2415100A1 (en) |
| IL (1) | IL153764A0 (en) |
| MX (1) | MXPA03000306A (en) |
| NO (1) | NO20030128L (en) |
| SG (1) | SG136804A1 (en) |
| WO (1) | WO2002004021A1 (en) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL146005A0 (en) | 1999-05-07 | 2002-07-25 | Genentech Inc | Treatment of autoimmune diseases with antagonists which bind to b cell surface markers |
| WO2001097858A2 (en) * | 2000-06-20 | 2001-12-27 | Idec Pharmaceuticals Corporation | Cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination |
| MXPA03002262A (en) * | 2000-09-18 | 2003-10-15 | Idec Pharma Corp | Combination therapy for treatment of autoimmune diseases using b cell depleting/immunoregulatory antibody combination. |
| ATE391174T1 (en) | 2000-10-20 | 2008-04-15 | Chugai Pharmaceutical Co Ltd | MODIFIED TPO AGONIST ANTIBODY |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| AU2002243718B2 (en) * | 2001-01-31 | 2007-12-06 | Biogen Idec Inc. | Use of immunoregulatory antibodies in the treatment of neoplastic disorders |
| AU2002250352C1 (en) * | 2001-04-02 | 2009-04-30 | Genentech, Inc. | Combination therapy |
| AU2003210266A1 (en) * | 2002-02-14 | 2003-09-04 | Bioinvent International Ab | Treatment, diagnosis and imaging of disease |
| GB0210121D0 (en) * | 2002-05-02 | 2002-06-12 | Celltech R&D Ltd | Biological products |
| CN1729203B (en) | 2002-10-17 | 2014-02-19 | 根马布股份公司 | Anti-CD20 Human Monoclonal Antibody |
| WO2004056312A2 (en) | 2002-12-16 | 2004-07-08 | Genentech, Inc. | Immunoglobulin variants and uses thereof |
| JP2004279086A (en) | 2003-03-13 | 2004-10-07 | Konica Minolta Holdings Inc | Radiation image conversion panel and method for manufacturing it |
| EP1609803A4 (en) * | 2003-03-31 | 2006-05-24 | Chugai Pharmaceutical Co Ltd | MODIFIED ANTIBODY AGAINST CD22 AND ITS USE |
| BRPI0409534A (en) | 2003-04-09 | 2006-04-18 | Genentech Inc | methods for treating autoimmune disease and rheumatoid arthritis, method of reducing the risk of negative side effect, use of an antagonist that binds to a b-cell surface marker, and use of an cd20-binding antibody |
| PT2272868E (en) | 2003-06-05 | 2015-07-07 | Genentech Inc | Combination therapy for b cell disorders |
| NZ546173A (en) | 2003-10-16 | 2009-04-30 | Micromet Ag | Multispecific deimmunized CD3-binders |
| US8277810B2 (en) | 2003-11-04 | 2012-10-02 | Novartis Vaccines & Diagnostics, Inc. | Antagonist anti-CD40 antibodies |
| EP1684869B1 (en) * | 2003-11-04 | 2011-07-20 | Novartis Vaccines and Diagnostics, Inc. | Methods of therapy for b cell-related cancers |
| DK2380910T3 (en) | 2003-11-05 | 2015-10-19 | Roche Glycart Ag | Antigen binding molecules with increased Fc receptor binding affinity and effector function |
| US7850962B2 (en) | 2004-04-20 | 2010-12-14 | Genmab A/S | Human monoclonal antibodies against CD20 |
| CN102512675A (en) | 2004-06-04 | 2012-06-27 | 健泰科生物技术公司 | Method for treating multiple sclerosis |
| US8444973B2 (en) | 2005-02-15 | 2013-05-21 | Duke University | Anti-CD19 antibodies and uses in B cell disorders |
| EP2548575A1 (en) * | 2005-02-15 | 2013-01-23 | Duke University | Anti-CD19 antibodies that mediate ADCC for use in treating autoimmune diseases |
| EP3623473A1 (en) | 2005-03-31 | 2020-03-18 | Chugai Seiyaku Kabushiki Kaisha | Process for production of polypeptide by regulation of assembly |
| US9493569B2 (en) | 2005-03-31 | 2016-11-15 | Chugai Seiyaku Kabushiki Kaisha | Structural isomers of sc(Fv)2 |
| DK1874821T3 (en) | 2005-04-26 | 2013-07-08 | Trion Pharma Gmbh | Combination of antibodies with glycocorticoids to treat cancer |
| US7601335B2 (en) | 2005-05-20 | 2009-10-13 | Genentech, Inc. | Pretreatment of a biological sample from an autoimmune disease subject |
| KR101360671B1 (en) | 2005-06-10 | 2014-02-07 | 추가이 세이야쿠 가부시키가이샤 | Pharmaceutical compositions containing sc(Fv)2 |
| WO2006132363A1 (en) | 2005-06-10 | 2006-12-14 | Chugai Seiyaku Kabushiki Kaisha | Stabilizer for protein preparation comprising meglumine and use thereof |
| CN105012953B (en) | 2005-07-25 | 2018-06-22 | 阿普泰沃研发有限责任公司 | B- cells are reduced with CD37- specificity and CD20- specific binding molecules |
| US20080213273A1 (en) | 2005-07-25 | 2008-09-04 | Trubion Pharmaceuticals Inc. | Single dose use of CD20-specific binding molecules |
| ATE497392T1 (en) | 2005-08-18 | 2011-02-15 | Genmab As | THERAPY WITH ANTI-CD4 ANTIBODIES AND RADIATION |
| KR20080073725A (en) | 2005-11-01 | 2008-08-11 | 노파르티스 아게 | Use of anti-CD40 antibodies |
| WO2007062090A2 (en) | 2005-11-23 | 2007-05-31 | Genentech, Inc. | Methods and compositions related to b cell assays |
| ES2654040T3 (en) | 2006-03-31 | 2018-02-12 | Chugai Seiyaku Kabushiki Kaisha | Antibody modification method for the purification of bispecific antibodies |
| EP2019841A2 (en) | 2006-04-21 | 2009-02-04 | Novartis AG | Antagonist anti-cd40 antibody pharmaceutical compositions |
| KR101571027B1 (en) | 2006-06-12 | 2015-11-23 | 이머전트 프로덕트 디벨롭먼트 시애틀, 엘엘씨 | Single chain polyvalent binding protein with effector function |
| JP5687057B2 (en) | 2007-07-09 | 2015-03-18 | ジェネンテック, インコーポレイテッド | Prevention of disulfide bond reduction during recombinant production of polypeptides. |
| US8956611B2 (en) | 2007-10-16 | 2015-02-17 | Zymogenetics, Inc. | Combination of BLyS inhibition and anti-CD 20 agents for treatment of autoimmune disease |
| EP2077281A1 (en) | 2008-01-02 | 2009-07-08 | Bergen Teknologioverforing AS | Anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
| US7914785B2 (en) | 2008-01-02 | 2011-03-29 | Bergen Teknologieverforing As | B-cell depleting agents, like anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
| MX340204B (en) | 2008-04-11 | 2016-06-30 | Emergent Product Dev Seattle | Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof. |
| TW201014605A (en) | 2008-09-16 | 2010-04-16 | Genentech Inc | Methods for treating progressive multiple sclerosis |
| WO2010075249A2 (en) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | A method for treating rheumatoid arthritis with b-cell antagonists |
| MX2012001742A (en) | 2009-08-11 | 2012-03-21 | Genentech Inc | Production of proteins in glutamine-free cell culture media. |
| AU2011215900A1 (en) | 2010-02-10 | 2012-07-26 | Immunogen, Inc. | CD20 antibodies and uses thereof |
| SG10201501803YA (en) | 2010-03-12 | 2015-05-28 | Immunogen Inc | Cd37-binding molecules and immunoconjugates thereof |
| AR083847A1 (en) | 2010-11-15 | 2013-03-27 | Novartis Ag | FC VARIANTS (CONSTANT FRAGMENT) SILENCERS OF ANTI-CD40 ANTIBODIES |
| CA2925256C (en) | 2013-09-27 | 2023-08-15 | Chugai Seiyaku Kabushiki Kaisha | Method for producing polypeptide heteromultimer |
| MA41459A (en) | 2015-02-03 | 2017-12-12 | Als Therapy Development Inst | ANTI-CD40L ANTIBODIES AND METHODS FOR TREATING CD40L ILLNESSES OR DISORDERS |
| CA3225013A1 (en) | 2015-02-24 | 2016-09-01 | Bioatla, Llc | Conditionally active proteins |
| WO2016200676A1 (en) | 2015-06-08 | 2016-12-15 | Immunogen, Inc. | Anti-cd37 immunoconjugate and anti-cd20 antibody combinations |
| MY193078A (en) | 2015-06-24 | 2022-09-26 | Hoffmann La Roche | Anti-transferrin receptor antibodies with tailored affinity |
| CN108699144B (en) | 2015-08-28 | 2022-07-19 | 德彪发姆国际有限公司 | Antibodies and assays for detecting CD37 |
| HK1251480A1 (en) | 2015-09-21 | 2019-02-01 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
| RU2753390C1 (en) | 2015-10-02 | 2021-08-13 | Ф. Хоффманн-Ля Рош Аг | Bispecific antibodies to human cd20/human transferrin receptor and methods for their use |
| AR106189A1 (en) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | BIESPECTIFIC ANTIBODIES AGAINST HUMAN A-b AND THE HUMAN TRANSFERRINE RECEIVER AND METHODS OF USE |
| WO2017078839A1 (en) | 2015-11-02 | 2017-05-11 | Bioatla, Llc | Conditionally active polypeptides |
| KR102784832B1 (en) | 2015-12-28 | 2025-03-21 | 추가이 세이야쿠 가부시키가이샤 | Method for improving the efficiency of purification of Fc region-containing polypeptides |
| IL297519B2 (en) | 2016-04-27 | 2024-06-01 | Abbvie Inc | Methods of treatment of diseases in which il-13 activity is detrimental using anti-il-13 antibodies |
| JP2020510608A (en) | 2016-11-02 | 2020-04-09 | デビオファーム インターナショナル, エス. アー. | Method for improving anti-CD37 immunoconjugate therapy |
| JP7766392B2 (en) | 2017-05-24 | 2025-11-10 | エイエルエス・セラピー・デベロップメント・インスティテュート | Therapeutic anti-CD40 ligand antibodies |
| CN112218662A (en) | 2018-05-30 | 2021-01-12 | 德彪发姆国际有限公司 | anti-CD 37 immunoconjugate dosing regimen |
| EP4433506A1 (en) | 2021-11-16 | 2024-09-25 | Genentech, Inc. | Methods and compositions for treating systemic lupus erythematosus (sle) with mosunetuzumab |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5736137A (en) * | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| ATE196606T1 (en) * | 1992-11-13 | 2000-10-15 | Idec Pharma Corp | THERAPEUTIC USE OF CHIMERIC AND LABELED ANTIBODIES DIRECTED AGAINST A DIFFERENTIATION ANTIGEN WHICH EXPRESSION IS RESTRICTED TO HUMAN B LYMPHOCYTES, FOR THE TREATMENT OF B-CELL LYMPHOMA |
| US5595721A (en) * | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
| US6001358A (en) * | 1995-11-07 | 1999-12-14 | Idec Pharmaceuticals Corporation | Humanized antibodies to human gp39, compositions containing thereof |
-
2001
- 2001-05-16 KR KR1020087009742A patent/KR20080039547A/en not_active Ceased
- 2001-05-16 SG SG200500152-4A patent/SG136804A1/en unknown
- 2001-05-16 IL IL15376401A patent/IL153764A0/en unknown
- 2001-05-16 WO PCT/US2001/015677 patent/WO2002004021A1/en not_active Ceased
- 2001-05-16 CN CN01814063A patent/CN1446104A/en active Pending
- 2001-05-16 AU AU2001264612A patent/AU2001264612C1/en not_active Ceased
- 2001-05-16 AU AU6461201A patent/AU6461201A/en active Pending
- 2001-05-16 MX MXPA03000306A patent/MXPA03000306A/en not_active Application Discontinuation
- 2001-05-16 KR KR10-2003-7000429A patent/KR20030031957A/en not_active Ceased
- 2001-05-16 CA CA002415100A patent/CA2415100A1/en not_active Abandoned
- 2001-05-16 EP EP01939050A patent/EP1305045A1/en not_active Withdrawn
- 2001-05-16 JP JP2002508475A patent/JP2004502742A/en not_active Abandoned
-
2003
- 2003-01-10 NO NO20030128A patent/NO20030128L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001264612B2 (en) | 2007-02-22 |
| WO2002004021A1 (en) | 2002-01-17 |
| CA2415100A1 (en) | 2002-01-17 |
| JP2004502742A (en) | 2004-01-29 |
| IL153764A0 (en) | 2003-07-06 |
| EP1305045A1 (en) | 2003-05-02 |
| KR20080039547A (en) | 2008-05-07 |
| NO20030128D0 (en) | 2003-01-10 |
| WO2002004021A9 (en) | 2003-01-16 |
| CN1446104A (en) | 2003-10-01 |
| AU2001264612C1 (en) | 2007-11-22 |
| MXPA03000306A (en) | 2004-04-05 |
| AU6461201A (en) | 2002-01-21 |
| SG136804A1 (en) | 2007-11-29 |
| AU2001264612B8 (en) | 2007-02-22 |
| KR20030031957A (en) | 2003-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |