NO20024775D0 - Hydroksyfenyl-piperidin-4-yliden-metyl-benzamidderivater til behandling av smerte - Google Patents

Hydroksyfenyl-piperidin-4-yliden-metyl-benzamidderivater til behandling av smerte

Info

Publication number: NO20024775D0
Authority: NO; Norway
Prior art keywords: ylidene; piperidin; hydroxyphenyl; pain; methyl
Prior art date: 2000-04-04

Application number

NO20024775A

Other languages

English (en)

Other versions

NO20024775L (no

Inventor

William Brown

Christopher Walpole

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-04-04

Filing date

2002-10-03

Publication date

2002-10-03

2002-10-03 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2002-10-03 Publication of NO20024775D0 publication Critical patent/NO20024775D0/no

2002-12-03 Publication of NO20024775L publication Critical patent/NO20024775L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

NO20024775A 2000-04-04 2002-10-03 Hydroksyfenyl-piperidin-4-yliden-metyl-benzamid derivater til behandling avsmerte NO20024775L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0001207A SE0001207D0 (sv)	2000-04-04	2000-04-04	Novel compounds
PCT/SE2001/000707 WO2001074804A1 (en)	2000-04-04	2001-03-30	Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatement of pain

Publications (2)

Publication Number	Publication Date
NO20024775D0 true NO20024775D0 (no)	2002-10-03
NO20024775L NO20024775L (no)	2002-12-03

Family

ID=20279146

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20024775A NO20024775L (no)	2000-04-04	2002-10-03	Hydroksyfenyl-piperidin-4-yliden-metyl-benzamid derivater til behandling avsmerte

Country Status (28)

Country	Link
US (1)	US6756387B2 (no)
EP (1)	EP1282616B1 (no)
JP (1)	JP2003529596A (no)
KR (1)	KR20020084285A (no)
CN (1)	CN1185228C (no)
AR (1)	AR027983A1 (no)
AT (1)	ATE269324T1 (no)
AU (1)	AU2001244981A1 (no)
BR (1)	BR0109816A (no)
CA (1)	CA2404386A1 (no)
CZ (1)	CZ20023289A3 (no)
DE (1)	DE60103889T2 (no)
DK (1)	DK1282616T3 (no)
EE (1)	EE200200571A (no)
ES (1)	ES2220748T3 (no)
HU (1)	HUP0300427A2 (no)
IL (1)	IL151890A0 (no)
IS (1)	IS6575A (no)
MX (1)	MXPA02009757A (no)
NO (1)	NO20024775L (no)
NZ (1)	NZ522142A (no)
PL (1)	PL357780A1 (no)
PT (1)	PT1282616E (no)
RU (1)	RU2002125495A (no)
SE (1)	SE0001207D0 (no)
SK (1)	SK14232002A3 (no)
WO (1)	WO2001074804A1 (no)
ZA (1)	ZA200207968B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW548271B (en)	1996-12-20	2003-08-21	Astra Pharma Inc	Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE0101769D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101770D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101773D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101765D0 (sv)	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101771D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101766D0 (sv)	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101768D0 (sv)	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101767D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0103313D0 (sv) *	2001-10-03	2001-10-03	Astrazeneca Ab	Novel compounds
TW200301701A (en)	2002-01-02	2003-07-16	Ardent Pharmaceuticals Inc	Method of treating sexual dysfunctions with delta opioid receptor agonist compounds
US8476280B2 (en) *	2002-05-09	2013-07-02	Versi Group, Llc	Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
SE0203301D0 (sv) *	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
SE0300104D0 (sv) *	2003-01-16	2003-01-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300105D0 (sv) *	2003-01-16	2003-01-16	Astrazeneca Ab	Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof
SE0300103D0 (sv) *	2003-01-16	2003-01-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300987D0 (sv) *	2003-04-03	2003-04-03	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301445D0 (sv) *	2003-05-16	2003-05-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301443D0 (sv) *	2003-05-16	2003-05-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301441D0 (sv) *	2003-05-16	2003-05-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301442D0 (sv) *	2003-05-16	2003-05-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations therof and uses thereof
JP2007503457A (ja) *	2003-05-16	2007-02-22	アストラゼネカ・アクチエボラーグ	ジアリールメチリデンピペリジン誘導体、その製造およびその使用
US7589103B2 (en) *	2003-06-27	2009-09-15	Janssen Pharmaceutica N.V.	Tricyclic-bridged piperidinylidene derivatives as 8-opioid modulators
SE0400026D0 (sv) *	2004-01-09	2004-01-09	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0402485D0 (sv)	2004-10-13	2004-10-13	Astrazeneca Ab	Polymorph of N,N-Diethyl-4-(3-Fluorophenyl-Piperidin-4-Ylidene-Methyl)-Benzamide Hydrochloride salt

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2898339A (en)	1957-07-29	1959-08-04	Wm S Merrell Co	N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine
US4581171A (en)	1983-07-27	1986-04-08	Janssen Pharmaceutica, N.V.	[[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders
US4816586A (en)	1987-07-29	1989-03-28	Regents Of The University Of Minnesota	Delta opioid receptor antagonists
US5140029A (en)	1989-01-09	1992-08-18	Janssen Pharmaceutica N.V.	2-aminopyrimidinone derivatives
US4939137A (en)	1989-06-28	1990-07-03	Ortho Pharmaceutical Corporation	Ring-fused thienopyrimidinedione derivatives
US5683998A (en)	1991-04-23	1997-11-04	Toray Industries, Inc.	Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
US5574159A (en)	1992-02-03	1996-11-12	Delta Pharmaceuticals, Inc.	Opioid compounds and methods for making therefor
GB9202238D0 (en)	1992-02-03	1992-03-18	Wellcome Found	Compounds
US5985880A (en) *	1996-06-05	1999-11-16	Delta Pharmaceuticals	Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds
SE9504661D0 (sv) *	1995-12-22	1995-12-22	Astra Pharma Inc	New compounds
TW548271B (en) *	1996-12-20	2003-08-21	Astra Pharma Inc	Novel piperidine derivatives having an exocyclic double bond with analgesic effects
ATE306472T1 (de) *	1997-12-24	2005-10-15	Ortho Mcneil Pharm Inc	(4)-(aryl(piperidin-4-yl) aminobenzamidderivate die an delta-opioid rezeptor binden

2000
- 2000-04-04 SE SE0001207A patent/SE0001207D0/xx unknown
2001
- 2001-03-28 AR ARP010101477A patent/AR027983A1/es not_active Application Discontinuation
- 2001-03-30 MX MXPA02009757A patent/MXPA02009757A/es unknown
- 2001-03-30 RU RU2002125495/04A patent/RU2002125495A/ru not_active Application Discontinuation
- 2001-03-30 HU HU0300427A patent/HUP0300427A2/hu unknown
- 2001-03-30 AT AT01918113T patent/ATE269324T1/de not_active IP Right Cessation
- 2001-03-30 AU AU2001244981A patent/AU2001244981A1/en not_active Abandoned
- 2001-03-30 EE EEP200200571A patent/EE200200571A/xx unknown
- 2001-03-30 CA CA002404386A patent/CA2404386A1/en not_active Abandoned
- 2001-03-30 WO PCT/SE2001/000707 patent/WO2001074804A1/en not_active Ceased
- 2001-03-30 DE DE60103889T patent/DE60103889T2/de not_active Expired - Fee Related
- 2001-03-30 EP EP01918113A patent/EP1282616B1/en not_active Expired - Lifetime
- 2001-03-30 ES ES01918113T patent/ES2220748T3/es not_active Expired - Lifetime
- 2001-03-30 PL PL01357780A patent/PL357780A1/xx not_active Application Discontinuation
- 2001-03-30 KR KR1020027013207A patent/KR20020084285A/ko not_active Withdrawn
- 2001-03-30 SK SK1423-2002A patent/SK14232002A3/sk not_active Application Discontinuation
- 2001-03-30 PT PT01918113T patent/PT1282616E/pt unknown
- 2001-03-30 JP JP2001572494A patent/JP2003529596A/ja active Pending
- 2001-03-30 DK DK01918113T patent/DK1282616T3/da active
- 2001-03-30 IL IL15189001A patent/IL151890A0/xx unknown
- 2001-03-30 NZ NZ522142A patent/NZ522142A/en unknown
- 2001-03-30 CN CNB018105939A patent/CN1185228C/zh not_active Expired - Fee Related
- 2001-03-30 US US10/240,038 patent/US6756387B2/en not_active Expired - Fee Related
- 2001-03-30 BR BR0109816-0A patent/BR0109816A/pt not_active IP Right Cessation
- 2001-03-30 CZ CZ20023289A patent/CZ20023289A3/cs unknown
2002
- 2002-09-30 IS IS6575A patent/IS6575A/is unknown
- 2002-10-03 ZA ZA200207968A patent/ZA200207968B/en unknown
- 2002-10-03 NO NO20024775A patent/NO20024775L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
PT1282616E (pt)	2004-10-29
DE60103889T2 (de)	2005-08-25
CA2404386A1 (en)	2001-10-11
HK1051690A1 (en)	2003-08-15
ZA200207968B (en)	2004-04-07
IL151890A0 (en)	2003-04-10
CN1432009A (zh)	2003-07-23
EP1282616A1 (en)	2003-02-12
NZ522142A (en)	2004-06-25
AR027983A1 (es)	2003-04-23
BR0109816A (pt)	2003-01-21
DK1282616T3 (da)	2004-09-20
DE60103889D1 (de)	2004-07-22
SK14232002A3 (sk)	2003-06-03
NO20024775L (no)	2002-12-03
RU2002125495A (ru)	2004-04-10
SE0001207D0 (sv)	2000-04-04
US20030187022A1 (en)	2003-10-02
EP1282616B1 (en)	2004-06-16
US6756387B2 (en)	2004-06-29
KR20020084285A (ko)	2002-11-04
ATE269324T1 (de)	2004-07-15
CN1185228C (zh)	2005-01-19
AU2001244981A1 (en)	2001-10-15
WO2001074804A1 (en)	2001-10-11
HUP0300427A2 (hu)	2003-06-28
MXPA02009757A (es)	2003-05-27
IS6575A (is)	2002-09-30
ES2220748T3 (es)	2004-12-16
JP2003529596A (ja)	2003-10-07
CZ20023289A3 (cs)	2003-03-12
PL357780A1 (en)	2004-07-26
EE200200571A (et)	2004-04-15

Publication	Publication Date	Title
NO20024775D0 (no)	2002-10-03	Hydroksyfenyl-piperidin-4-yliden-metyl-benzamidderivater til behandling av smerte
NO20014379L (no)	2001-11-07	Anvendelse av Xenon for behandling av Neurointoksikasjoner
NO20052894D0 (no)	2005-06-14	4-tetrazolyl-4-fenylpiperidin-derivater for behandling av smerte
NO20013369D0 (no)	2001-07-06	Arylpiperazinyl-cykloheksyl-indol-derivater for behandling av depresjon
NO20013380D0 (no)	2001-07-06	2-aminobenzoksazinonderivater for behandling av fedme
NO20031442L (no)	2003-05-26	Morfolin-acetamidderivater for behandling av inflammatoriske sykdommer
NO20013381D0 (no)	2001-07-06	2-oksybenzoksazinonderivater for behandling av fedme
NO20025792L (no)	2002-12-02	Kinazolinderivater for behandling av tumorer
NO20022087D0 (no)	2002-05-02	Fremgangsmåte for behandling av diabetes
IS6917A (is)	2003-08-18	Epóþílon afleiður til meðhöndlunar erfiðra æxla
NO20023482D0 (no)	2002-07-22	Fremgangsmåte for behandling av stoffmisbruk
NO20024776D0 (no)	2002-10-03	Hydroksyfenyl-piperazinyl-metyl-benzamidderivater til behandling av smerte
NO20024777L (no)	2002-12-03	Kinolinyl-piperidin-4-yliden-metyl-benzamid derivater til behandling av smerte
NO20033804D0 (no)	2003-08-26	Karbamatforbindelser for behandling av smerte
NO20026219L (no)	2003-02-17	Forbindelser for behandling av svekket fundisk relaksasjon
NO20020784L (no)	2002-02-18	Medikament for behandling av brudd
NO20030717D0 (no)	2003-02-14	Forbindelser for behandling av avhengighetsforstyrrelser
IS6020A (is)	2001-07-23	S-nítrósóþíól til meðferðar við blóðrásartruflunum
NO20014026L (no)	2001-10-17	Krampestillende derivater til behandling av betydelig skjelving
SE0300535L (sv)	2003-04-29	Behandling av brännskador
DK1286986T3 (da)	2005-05-09	Quinolinylpiperidin-4-ylidenmethylbenzamidderivater til behandling af smerte
HK1051687A (en)	2003-08-15	Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
NO996166L (no)	2000-06-15	FremgangsmÕte for behandling av avluter

Legal Events

Date	Code	Title	Description
2006-09-04	FC2A	Withdrawal, rejection or dismissal of laid open patent application