NO20022954D0 - Anvendelse av bioaktive metabolitter av gepiron for behandling av psykologiske forstyrrelser - Google Patents
Anvendelse av bioaktive metabolitter av gepiron for behandling av psykologiske forstyrrelserInfo
- Publication number
- NO20022954D0 NO20022954D0 NO20022954A NO20022954A NO20022954D0 NO 20022954 D0 NO20022954 D0 NO 20022954D0 NO 20022954 A NO20022954 A NO 20022954A NO 20022954 A NO20022954 A NO 20022954A NO 20022954 D0 NO20022954 D0 NO 20022954D0
- Authority
- NO
- Norway
- Prior art keywords
- gepirone
- psychological disorders
- treatment
- bioactive metabolites
- metabolites
- Prior art date
Links
- QOIGKGMMAGJZNZ-UHFFFAOYSA-N gepirone Chemical compound O=C1CC(C)(C)CC(=O)N1CCCCN1CCN(C=2N=CC=CN=2)CC1 QOIGKGMMAGJZNZ-UHFFFAOYSA-N 0.000 title abstract 3
- 230000000975 bioactive effect Effects 0.000 title abstract 2
- 229960000647 gepirone Drugs 0.000 title abstract 2
- 208000020016 psychiatric disease Diseases 0.000 title abstract 2
- 239000002207 metabolite Substances 0.000 title 1
- -1 3-OH gepirone (4 Chemical class 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000036470 plasma concentration Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17268499P | 1999-12-20 | 1999-12-20 | |
| US09/709,741 US6534507B1 (en) | 1999-12-20 | 2000-11-13 | Methods for treating psychological disorders using bioactive metabolites of gepirone |
| PCT/US2000/034131 WO2001045687A2 (en) | 1999-12-20 | 2000-12-18 | Use of bioactive metabolites of gepirone for the treatment of psychological disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20022954L NO20022954L (no) | 2002-06-19 |
| NO20022954D0 true NO20022954D0 (no) | 2002-06-19 |
| NO323304B1 NO323304B1 (no) | 2007-03-05 |
Family
ID=26868346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20022954A NO323304B1 (no) | 1999-12-20 | 2002-06-19 | Anvendelse av bioaktive metabolitter av gepiron for fremstilling av et medikament for behandling av psykologiske forstyrrelser og farmasoytisk sammensetning omfattende samme |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6534507B1 (no) |
| EP (1) | EP1242061B1 (no) |
| JP (1) | JP4236407B2 (no) |
| KR (1) | KR100602976B1 (no) |
| CN (1) | CN1411375A (no) |
| AT (1) | ATE294572T1 (no) |
| AU (1) | AU776409B2 (no) |
| CA (1) | CA2395458C (no) |
| CZ (1) | CZ300429B6 (no) |
| DE (1) | DE60019968T2 (no) |
| ES (1) | ES2241683T3 (no) |
| HU (1) | HU228963B1 (no) |
| IL (2) | IL150222A0 (no) |
| MX (1) | MXPA02006146A (no) |
| NO (1) | NO323304B1 (no) |
| NZ (1) | NZ519554A (no) |
| PL (1) | PL200378B1 (no) |
| PT (1) | PT1242061E (no) |
| RU (1) | RU2282448C2 (no) |
| WO (1) | WO2001045687A2 (no) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002016347A1 (en) * | 2000-08-22 | 2002-02-28 | Akzo Nobel N.V. | Active metabolite of gepirone |
| US20040002500A1 (en) * | 2002-06-28 | 2004-01-01 | Fabre Kramer Pharmaceutical, Inc. | Methods for treating attention deficit disorder |
| US20040000689A1 (en) * | 2002-06-28 | 2004-01-01 | Erh-Kun Lai | Dual-bit MONOS/SONOS memory structure with non-continuous floating gate |
| AU2003259086A1 (en) * | 2002-08-12 | 2004-02-25 | Bristol-Myers Squibb Company | Improved process for hydroxyazapirones |
| US20050004105A1 (en) * | 2003-01-29 | 2005-01-06 | Emer Leahy | Treatment for a attention-deficit hyperactivity disorder |
| TW200521125A (en) * | 2003-11-18 | 2005-07-01 | Bristol Myers Squibb Co | Continuous process for producing hydroxyazapirones by oxidation |
| EA013213B1 (ru) * | 2004-11-05 | 2010-04-30 | Фэйбр-Крэймер Холдингз, Инк. | Дозированная форма биоактивного метаболита гепирона с высокой дозировкой и длительным высвобождением, способ ее получения и способ лечения депрессии с ее использованием |
| BRPI0912516A2 (pt) * | 2008-05-08 | 2015-10-13 | Fabre Kramer Pharmaceuticals Inc | 3-hidróxi gepirona para o tratamento de distúrbio de défict de atenção e disfunção sexual |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4423049A (en) | 1981-12-28 | 1983-12-27 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines |
| US5185329A (en) * | 1988-08-30 | 1993-02-09 | Bristol-Myers Squibb Company | Method for treatment of substance addiction |
| CA2051399C (en) * | 1989-05-31 | 2003-12-30 | Chiu-Hong Lin | Therapeutically useful 2-aminotetralin derivatives |
| US4956368A (en) | 1989-07-24 | 1990-09-11 | Bristol-Myers Company | Metabolites and prodrug formulations of 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione |
| US5478572A (en) * | 1994-09-06 | 1995-12-26 | Bristol-Myers Squibb Co. | Gepirone dosage form |
-
2000
- 2000-11-13 US US09/709,741 patent/US6534507B1/en not_active Expired - Lifetime
- 2000-12-18 KR KR1020027007927A patent/KR100602976B1/ko not_active Expired - Lifetime
- 2000-12-18 NZ NZ519554A patent/NZ519554A/en not_active IP Right Cessation
- 2000-12-18 HU HU0301831A patent/HU228963B1/hu unknown
- 2000-12-18 RU RU2002119400/14A patent/RU2282448C2/ru active
- 2000-12-18 CZ CZ20022137A patent/CZ300429B6/cs not_active IP Right Cessation
- 2000-12-18 AU AU22687/01A patent/AU776409B2/en not_active Expired
- 2000-12-18 EP EP00986449A patent/EP1242061B1/en not_active Expired - Lifetime
- 2000-12-18 IL IL15022200A patent/IL150222A0/xx unknown
- 2000-12-18 ES ES00986449T patent/ES2241683T3/es not_active Expired - Lifetime
- 2000-12-18 AT AT00986449T patent/ATE294572T1/de active
- 2000-12-18 CA CA002395458A patent/CA2395458C/en not_active Expired - Lifetime
- 2000-12-18 DE DE60019968T patent/DE60019968T2/de not_active Expired - Lifetime
- 2000-12-18 WO PCT/US2000/034131 patent/WO2001045687A2/en not_active Ceased
- 2000-12-18 JP JP2001546426A patent/JP4236407B2/ja not_active Expired - Lifetime
- 2000-12-18 PL PL364936A patent/PL200378B1/pl unknown
- 2000-12-18 CN CN00817455A patent/CN1411375A/zh active Pending
- 2000-12-18 MX MXPA02006146A patent/MXPA02006146A/es active IP Right Grant
- 2000-12-18 PT PT00986449T patent/PT1242061E/pt unknown
-
2002
- 2002-06-13 IL IL150222A patent/IL150222A/en active IP Right Grant
- 2002-06-19 NO NO20022954A patent/NO323304B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1242061A2 (en) | 2002-09-25 |
| DE60019968D1 (de) | 2005-06-09 |
| JP2004500362A (ja) | 2004-01-08 |
| MXPA02006146A (es) | 2004-08-23 |
| JP4236407B2 (ja) | 2009-03-11 |
| ES2241683T3 (es) | 2005-11-01 |
| HUP0301831A2 (hu) | 2003-09-29 |
| KR100602976B1 (ko) | 2006-07-20 |
| IL150222A0 (en) | 2002-12-01 |
| ATE294572T1 (de) | 2005-05-15 |
| WO2001045687A2 (en) | 2001-06-28 |
| NO323304B1 (no) | 2007-03-05 |
| KR20020082470A (ko) | 2002-10-31 |
| CA2395458A1 (en) | 2001-06-28 |
| RU2282448C2 (ru) | 2006-08-27 |
| IL150222A (en) | 2009-09-22 |
| AU2268701A (en) | 2001-07-03 |
| AU776409B2 (en) | 2004-09-09 |
| PL364936A1 (en) | 2004-12-27 |
| PL200378B1 (pl) | 2008-12-31 |
| PT1242061E (pt) | 2005-09-30 |
| WO2001045687A3 (en) | 2002-04-25 |
| DE60019968T2 (de) | 2006-02-02 |
| US6534507B1 (en) | 2003-03-18 |
| NZ519554A (en) | 2005-01-28 |
| NO20022954L (no) | 2002-06-19 |
| CN1411375A (zh) | 2003-04-16 |
| RU2002119400A (ru) | 2004-01-27 |
| CA2395458C (en) | 2009-05-12 |
| CZ300429B6 (cs) | 2009-05-20 |
| EP1242061B1 (en) | 2005-05-04 |
| CZ20022137A3 (cs) | 2003-03-12 |
| HU228963B1 (en) | 2013-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |