NO20021701D0 - Fremgangsmåte for fremstilling av et konjugat av polyglutamat og et terapeutisk middel - Google Patents
Fremgangsmåte for fremstilling av et konjugat av polyglutamat og et terapeutisk middelInfo
- Publication number
- NO20021701D0 NO20021701D0 NO20021701A NO20021701A NO20021701D0 NO 20021701 D0 NO20021701 D0 NO 20021701D0 NO 20021701 A NO20021701 A NO 20021701A NO 20021701 A NO20021701 A NO 20021701A NO 20021701 D0 NO20021701 D0 NO 20021701D0
- Authority
- NO
- Norway
- Prior art keywords
- polyglutamate
- conjugate
- preparation
- therapeutic agent
- therapeutic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polyamides (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15913599P | 1999-10-12 | 1999-10-12 | |
| PCT/US2000/028109 WO2001026693A2 (en) | 1999-10-12 | 2000-10-12 | Manufacture of polyglutamate-therapeutic agent conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20021701D0 true NO20021701D0 (no) | 2002-04-11 |
| NO20021701L NO20021701L (no) | 2002-05-23 |
Family
ID=22571222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20021701A NO20021701L (no) | 1999-10-12 | 2002-04-11 | Fremgangsmåte for fremstilling av et konjugat av polyglutamat og et terapeutisk middel |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20020077279A1 (no) |
| EP (2) | EP1466627A1 (no) |
| JP (1) | JP2003511423A (no) |
| KR (1) | KR100821437B1 (no) |
| CN (2) | CN1607962A (no) |
| AU (1) | AU781735B2 (no) |
| BR (1) | BRPI0014652B1 (no) |
| CA (1) | CA2387611C (no) |
| HU (1) | HUP0203123A3 (no) |
| MX (1) | MXPA02003719A (no) |
| NO (1) | NO20021701L (no) |
| NZ (1) | NZ529789A (no) |
| PL (1) | PL354623A1 (no) |
| SG (1) | SG147286A1 (no) |
| WO (1) | WO2001026693A2 (no) |
| ZA (1) | ZA200202695B (no) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6685301A (en) | 2000-06-14 | 2001-12-24 | Corixa Corp | Prodrug compounds with isoleucine |
| US6872715B2 (en) | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
| KR100817232B1 (ko) | 2003-04-22 | 2008-03-27 | 소시에떼 더 콘세이유 더 레세르세 에 다플리까띠옹 시엔띠피끄, 에스.아.에스. | 펩타이드 벡터 |
| FR2855521B1 (fr) * | 2003-05-28 | 2005-08-05 | Flamel Tech Sa | Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques. |
| US7259156B2 (en) | 2004-05-20 | 2007-08-21 | Kosan Biosciences Incorporated | Geldanamycin compounds and method of use |
| US8614228B2 (en) | 2004-08-11 | 2013-12-24 | Arqule, Inc. | Quinone prodrug compositions and methods of use |
| WO2006020719A2 (en) | 2004-08-11 | 2006-02-23 | Arqule, Inc. | Aminoacid conjugates of beta - lapachone for tumor targeting |
| BRPI0515573A (pt) | 2004-09-22 | 2008-07-29 | Nippon Kayaku Kk | copolìmero por blocos, preparação de micela e agente anticáncer contendo a mesma como o ingrediente ativo |
| US20070128118A1 (en) | 2005-12-05 | 2007-06-07 | Nitto Denko Corporation | Polyglutamate-amino acid conjugates and methods |
| TWI322010B (en) * | 2005-12-06 | 2010-03-21 | Cell Therapeutics Inc | Estrogen cancer therapy |
| US7462627B2 (en) * | 2006-02-09 | 2008-12-09 | Enzon Pharmaceuticals, Inc. | Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers |
| US7671067B2 (en) * | 2006-02-09 | 2010-03-02 | Enzon Pharmaceuticals, Inc. | Treatment of non-hodgkin's lymphomas with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamtothecin |
| KR20080106254A (ko) | 2006-03-28 | 2008-12-04 | 니폰 가야꾸 가부시끼가이샤 | 탁산류의 고분자 결합체 |
| AU2007252678A1 (en) | 2006-05-18 | 2007-11-29 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of podophyllotoxin |
| EP2080779B1 (en) | 2006-11-06 | 2016-05-18 | Nippon Kayaku Kabushiki Kaisha | Polymeric derivative of nucleic acid metabolic antagonist |
| WO2008056654A1 (fr) | 2006-11-08 | 2008-05-15 | Nippon Kayaku Kabushiki Kaisha | Dérivé polymère d'un antagoniste métabolique d'acide nucléique |
| CN101209350B (zh) * | 2006-12-30 | 2011-09-07 | 中国人民解放军军事医学科学院毒物药物研究所 | 以氨基酸为连接子的多聚谷氨酸-药物偶合物 |
| KR20090108082A (ko) * | 2007-02-09 | 2009-10-14 | 엔존 파마슈티컬즈, 인코포레이티드 | 7-에틸-10-하이드록시캄토테신 다분지형 고분자 접합체를 이용한 내성 또는 불응성 암의 치료방법 |
| CN104800856A (zh) * | 2007-04-10 | 2015-07-29 | 日东电工株式会社 | 多功能聚谷氨酸盐药物载体 |
| BRPI0810717A2 (pt) | 2007-04-30 | 2016-05-24 | Arqule Inc | sulfonato hidroxi de composto de quinona e seus usos |
| EP2155253A2 (en) * | 2007-05-09 | 2010-02-24 | Nitto Denko Corporation | Polyglutamate conjugates and polyglutamate-amino acid conjugates having a plurality of drugs |
| US8197828B2 (en) * | 2007-05-09 | 2012-06-12 | Nitto Denko Corporation | Compositions that include a hydrophobic compound and a polyamino acid conjugate |
| CN101730549B (zh) * | 2007-05-09 | 2015-12-09 | 日东电工株式会社 | 与铂类药物结合的聚合物 |
| EP2206502B1 (en) | 2007-09-28 | 2018-09-12 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of steroid |
| CN104096236A (zh) * | 2008-03-06 | 2014-10-15 | 日东电工株式会社 | 用于治疗癌症的聚合物紫杉醇结合物和方法 |
| KR101589582B1 (ko) | 2008-03-18 | 2016-01-28 | 니폰 가야꾸 가부시끼가이샤 | 생리활성물질의 고분자량 결합체 |
| US9149540B2 (en) | 2008-05-08 | 2015-10-06 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of folic acid or folic acid derivative |
| WO2010025337A1 (en) * | 2008-08-29 | 2010-03-04 | Enzon Pharmaceuticals, Inc. | Method of treating ras associated cancer |
| CN105879044A (zh) * | 2008-10-07 | 2016-08-24 | 瑞沙恩医药公司 | Hpma-多西他赛或吉西他滨缀合物及其用途 |
| CA2739291A1 (en) * | 2008-10-15 | 2010-04-22 | Nitto Denko Corporation | Method of preparing polyglutamate conjugates |
| CA2738807A1 (en) * | 2008-10-21 | 2010-04-29 | Enzon Pharmaceuticals, Inc. | Treatment of neuroblastoma with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin |
| DE102008060549A1 (de) * | 2008-12-04 | 2010-06-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung |
| EP2431403B1 (en) | 2009-05-15 | 2016-09-28 | Nipponkayaku Kabushikikaisha | Polymer conjugate of bioactive substance having hydroxy group |
| MX2012004416A (es) | 2009-10-13 | 2012-05-08 | Rexahn Pharmaceuticals Inc | Sistemas polimericos para el suministro de agentes anticancer. |
| BR112012022337A2 (pt) * | 2010-03-11 | 2016-07-05 | Nitto Denko Corp | composição e respectivos método de preparação e uso de quantidade eficaz |
| EP4450523A3 (en) | 2010-04-02 | 2025-03-12 | Amunix Pharmaceuticals, Inc. | Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same |
| CA2816997A1 (en) | 2010-11-17 | 2012-05-24 | Nippon Kayaku Kabushiki Kaisha | Novel polymer derivative of cytidine metabolic antagonist |
| CN102649810A (zh) * | 2011-05-19 | 2012-08-29 | 东北林业大学 | 喜树碱衍生物、其制备方法和用途 |
| US8691284B2 (en) | 2011-07-07 | 2014-04-08 | Empire Technology Development Llc | Fluorinated block co-polymers |
| BR112014005452B1 (pt) | 2011-09-11 | 2021-03-16 | Nippon Kayaku Kabushiki Kaisha | método de produção de copolímero de bloco |
| US8383093B1 (en) | 2011-11-01 | 2013-02-26 | Serina Therapeutics, Inc. | Subcutaneous delivery of poly(oxazoline) conjugates |
| US8907045B2 (en) | 2012-04-03 | 2014-12-09 | Empire Technology Development Llc | Biocompatible adhesive polymers |
| US9839694B2 (en) | 2013-04-26 | 2017-12-12 | Nitto Denko Corporation | Reduction of endotoxins from polyanionic polymer conjugates |
| KR101507119B1 (ko) * | 2013-05-31 | 2015-03-30 | 주식회사 바이오리더스 | 점막 점착성 폴리감마글루탐산 나노마이셀 및 이를 이용한 약물 전달체 |
| CN106267227A (zh) * | 2016-08-12 | 2017-01-04 | 北京蓝贝望生物医药科技股份有限公司 | 抗肿瘤药物 |
| CN106750272B (zh) * | 2016-12-05 | 2019-05-28 | 福建卫生职业技术学院 | 一种水溶性蛇葡萄素聚合物 |
| CN110123748A (zh) * | 2019-04-22 | 2019-08-16 | 南京师范大学 | 一种叶酸介导的靶向双载药聚合物胶束及其制备方法和应用 |
| CN113773282A (zh) * | 2021-09-22 | 2021-12-10 | 无锡紫杉药业有限公司 | 一种10-乙酰紫杉醇的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4356166A (en) * | 1978-12-08 | 1982-10-26 | University Of Utah | Time-release chemical delivery system |
| US5629433A (en) * | 1994-07-18 | 1997-05-13 | Hauser, Inc. | Selective process for the deacylation and deacetylation of taxol and taxanes |
| CA2192725C (en) * | 1995-12-28 | 2004-04-20 | Kenji Tsujihara | Camptothecin derivatives |
| IL126179A (en) * | 1996-03-12 | 2003-04-10 | Pg Txl Co Lp | Pharmaceutical compositions containing anti-tumor drug conjugates |
| US6441025B2 (en) * | 1996-03-12 | 2002-08-27 | Pg-Txl Company, L.P. | Water soluble paclitaxel derivatives |
| CN1429121A (zh) * | 2000-03-17 | 2003-07-09 | 细胞治疗公司 | 聚谷氨酸－喜树碱结合物及其制备方法 |
-
2000
- 2000-10-12 MX MXPA02003719A patent/MXPA02003719A/es active IP Right Grant
- 2000-10-12 JP JP2001529754A patent/JP2003511423A/ja active Pending
- 2000-10-12 BR BRPI0014652A patent/BRPI0014652B1/pt not_active IP Right Cessation
- 2000-10-12 AU AU10793/01A patent/AU781735B2/en not_active Ceased
- 2000-10-12 NZ NZ529789A patent/NZ529789A/en not_active IP Right Cessation
- 2000-10-12 EP EP04013703A patent/EP1466627A1/en not_active Withdrawn
- 2000-10-12 EP EP00972079A patent/EP1225917A2/en not_active Withdrawn
- 2000-10-12 CN CNA008170290A patent/CN1607962A/zh active Pending
- 2000-10-12 KR KR1020027004640A patent/KR100821437B1/ko not_active Expired - Fee Related
- 2000-10-12 HU HU0203123A patent/HUP0203123A3/hu unknown
- 2000-10-12 WO PCT/US2000/028109 patent/WO2001026693A2/en not_active Ceased
- 2000-10-12 CN CNA2009101276554A patent/CN101507820A/zh active Pending
- 2000-10-12 CA CA2387611A patent/CA2387611C/en not_active Expired - Fee Related
- 2000-10-12 PL PL00354623A patent/PL354623A1/xx not_active IP Right Cessation
- 2000-10-12 SG SG200401981-6A patent/SG147286A1/en unknown
-
2001
- 2001-10-09 US US09/971,657 patent/US20020077279A1/en not_active Abandoned
-
2002
- 2002-04-05 ZA ZA200202695A patent/ZA200202695B/en unknown
- 2002-04-11 NO NO20021701A patent/NO20021701L/no not_active Application Discontinuation
-
2003
- 2003-04-02 US US10/404,152 patent/US7399860B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7399860B2 (en) | 2008-07-15 |
| US20030224971A1 (en) | 2003-12-04 |
| HUP0203123A3 (en) | 2004-12-28 |
| AU1079301A (en) | 2001-04-23 |
| MXPA02003719A (es) | 2002-08-30 |
| CA2387611C (en) | 2011-03-29 |
| BRPI0014652B1 (pt) | 2016-08-09 |
| BR0014652A (pt) | 2003-06-10 |
| US20020077279A1 (en) | 2002-06-20 |
| JP2003511423A (ja) | 2003-03-25 |
| EP1225917A2 (en) | 2002-07-31 |
| AU781735B2 (en) | 2005-06-09 |
| HUP0203123A2 (hu) | 2003-01-28 |
| NO20021701L (no) | 2002-05-23 |
| CN1607962A (zh) | 2005-04-20 |
| WO2001026693A3 (en) | 2001-12-27 |
| NZ529789A (en) | 2005-04-29 |
| KR100821437B1 (ko) | 2008-04-10 |
| PL354623A1 (en) | 2004-02-09 |
| WO2001026693A2 (en) | 2001-04-19 |
| ZA200202695B (en) | 2004-02-25 |
| EP1466627A1 (en) | 2004-10-13 |
| CN101507820A (zh) | 2009-08-19 |
| KR20020059616A (ko) | 2002-07-13 |
| CA2387611A1 (en) | 2001-04-19 |
| SG147286A1 (en) | 2008-11-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20021701D0 (no) | Fremgangsmåte for fremstilling av et konjugat av polyglutamat og et terapeutisk middel | |
| NO20014560D0 (no) | Quinasoliner og terapautisk anvendelse derav | |
| NO20016143D0 (no) | Amfifile legemiddel-oligomer-konjugater med hydrolyserbare lipofile komponenter og fremgangsmåter for fremstilling oganvendelse av det samme | |
| NO20015542D0 (no) | Fremgangsmåte for fremstilling og anvendelse av N- desmetylzopikloner | |
| NO963015L (no) | Tetracykliske derivater, fremgangsmåte for fremstilling og anvendelse | |
| NO20004098L (no) | FremgangsmÕter og preparater for behandling av makrofag- formidlede lidelser | |
| NO20013560L (no) | Polymorfer av telmisartan, fremgangsmåter for fremstilling derav og anvendelse derav for fremstilling av et medikament | |
| CY2013032I2 (el) | Συζυγη της εξενδινης-4 και η φαρμακευτικη τους χρηση | |
| NO20014013L (no) | 16-halogen-epotilonderivater, fremgangsmåter for fremstilling av disse og farmasöytisk anvendelse av dem | |
| NO20021379D0 (no) | Benzodiazepin-derivater, fremstilling og anvendelse derav | |
| NO20012567D0 (no) | Azepinoindolderivater, fremstilling og anvendelse derav | |
| PL349355A1 (en) | Diaryl derivatives and their application as therapeutic agents | |
| GB0004167D0 (en) | 1-piperidinyl-propan-2-ol derivatives and their use as therapeutic agents | |
| NO20011409D0 (no) | Farmasøytiske midler for behandling av Parkinsonssykdom, ADHD og mikroadenomer | |
| NO20012963L (no) | Fremgangsmåte for fremstilling av 3-alkanoylindoler og 3- alkylindoler | |
| NO994165D0 (no) | Anvendelse av deskarboetoksyloratadin for fremstilling av et medikament for behandling av urininkontinens, reisesyke og svimmelhet | |
| NO20021094L (no) | Profylaktiske og terapeutiske medikamenter for oftalmologiske sykdommer | |
| NO955326D0 (no) | Isokinolinderivater, fremgangsmåte for deres fremstilling og terapeutiske anvendelse | |
| DK1138677T3 (da) | Fremgangsmåde til fremstilling af 11-amino-3-chlor-6,11-dihydro-5,5-dioxo-6-methyl-dibenzo[c,f][1,2]-thiazepin og anvendelse til syntese af tianeptin | |
| NO983926L (no) | Farmas°ytisk kombinasjonspreparat av en inhibitor av natrium-hydrogen-veksler og et legemiddel for behandling av hjertekretsl°p-sykdommer | |
| NO20001909D0 (no) | Fremgangsmõte og anlegg for fremstilling av 1,2-dikloretan | |
| NO992676D0 (no) | 1,4-diazabicyklo[2,2,2]okt-2-ylmetylderivater, deres fremstilling og terapeutiske anvendelse | |
| PL363048A1 (en) | Azabicyclic derivatives and their therapeutic use | |
| NO20015848D0 (no) | Polymorfer av et krystallinsk azabicyclo(2,2,2)oktan-3- amincitrat og farmasöytiske preparater derav | |
| HUP0203468A3 (en) | Betha-d-5-thioxylose derivatives, preparation method and therapeutic use thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |