NO20016381D0 - Dinukleotidkrystaller - Google Patents

Dinukleotidkrystaller

Info

Publication number: NO20016381D0
Authority: NO; Norway
Prior art keywords: dcp4u; present; monophosphate; raw material; ump
Prior art date: 1999-06-30

Application number

NO20016381A

Other languages

English (en)

Other versions

NO20016381L (no

NO321169B1 (no

Inventor

Kenya Mori

Takanori Miyashita

Hideaki Maeda

Hiroshi Sato

Yutaka Noda

Original Assignee

Yamasa Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-30

Filing date

2001-12-27

Publication date

2001-12-27

2001-12-27 Application filed by Yamasa Corp filed Critical Yamasa Corp

2001-12-27 Publication of NO20016381D0 publication Critical patent/NO20016381D0/no

2002-02-28 Publication of NO20016381L publication Critical patent/NO20016381L/no

2006-03-27 Publication of NO321169B1 publication Critical patent/NO321169B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO20016381A 1999-06-30 2001-12-27 Dinukleotidkrystaller NO321169B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP18495099		1999-06-30
PCT/JP2000/004336 WO2001002416A1 (en)	1999-06-30	2000-06-30	Dinucleotide crystals

Publications (3)

Publication Number	Publication Date
NO20016381D0 true NO20016381D0 (no)	2001-12-27
NO20016381L NO20016381L (no)	2002-02-28
NO321169B1 NO321169B1 (no)	2006-03-27

Family

ID=16162200

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20016381A NO321169B1 (no)	1999-06-30	2001-12-27	Dinukleotidkrystaller

Country Status (22)

Country	Link
US (1)	US6617444B1 (no)
EP (2)	EP1191032B1 (no)
JP (1)	JP3421666B2 (no)
KR (1)	KR100593723B1 (no)
CN (1)	CN1144811C (no)
AT (2)	ATE300551T1 (no)
AU (1)	AU767136B2 (no)
BR (1)	BR0012205A (no)
CA (1)	CA2376860C (no)
CZ (1)	CZ303172B6 (no)
DE (2)	DE60006814T2 (no)
EA (1)	EA004707B1 (no)
ES (2)	ES2245431T3 (no)
HU (1)	HU229225B1 (no)
IL (1)	IL147163A (no)
MX (1)	MXPA02000035A (no)
NO (1)	NO321169B1 (no)
NZ (1)	NZ516301A (no)
PL (2)	PL202200B1 (no)
SK (1)	SK284178B6 (no)
WO (1)	WO2001002416A1 (no)
ZA (1)	ZA200110468B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7223744B2 (en)	1997-02-10	2007-05-29	Inspire Pharmaceuticals, Inc.	Pharmaceutical formulation comprising dinucleoside polyphosphates and salts thereof
US6818629B2 (en)	1997-02-10	2004-11-16	Inspire Pharmaceuticals, Inc.	Pharmaceutical formulation comprising P1-(2'-deoxycytidine 5'-)P4-(uridine 5'-) tetraphosphate
US7078391B2 (en)	1997-02-10	2006-07-18	Inspire Pharmaceuticals, Inc.	Method of treating edematous retinal disorders
US6872710B2 (en)	1997-07-25	2005-03-29	Inspire Pharmaceuticals, Inc.	Di(uridine 5′)-tetraphosphate and salts thereof
US6548658B2 (en) *	1997-07-25	2003-04-15	Inspire Pharmaceuticals, Inc.	Di-(uridine 5′)-tetraphosphate and salts thereof
DE60006814T2 (de) *	1999-06-30	2004-05-19	Yamasa Corp., Choshi	Dinucleotid-kristalle
US6867199B2 (en)	2000-08-21	2005-03-15	Inspire Pharmaceuticals, Inc.	Dinucleoside polyphosphate compositions and their therapeutic use
US7161029B2 (en) *	2003-12-17	2007-01-09	Ajinomoto Co., Inc.	DiL-lysine monosulfate trihydrate crystal and method of making
CN100363376C (zh) *	2006-06-12	2008-01-23	南京工业大学	一种5’-核苷三磷酸钠盐的结晶方法
KR102116170B1 (ko) *	2015-06-29	2020-05-27	야마사 쇼유 가부시키가이샤	P1, p4-비스(5''-우리딜)테트라포스페이트 결정의 보관 방법
CA3039053C (en) *	2016-10-25	2021-04-20	Yamasa Corporation	Method for purifying p1,p4-di(uridine 5'-)tetraphosphate
CN111253456B (zh) *	2020-03-13	2021-05-11	广东先强药业有限公司	一种地纽福索钠的制备方法
CN111704637A (zh) *	2020-06-28	2020-09-25	南京工业大学	一种采用膜蒸馏结晶精制核苷酸的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07242685A (ja) *	1994-01-12	1995-09-19	Unitika Ltd	ジアデノシン四リン酸水和物の製造方法
US5837861A (en) *	1997-02-10	1998-11-17	Inspire Pharmaceuticals, Inc.	Dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency
US5900407A (en) *	1997-02-06	1999-05-04	Inspire Pharmaceuticals, Inc.	Method of treating dry eye disease with uridine triphosphates and related compounds
US6348589B1 (en)	1997-02-06	2002-02-19	Inspire Pharmaceuticals, Inc.	Certain dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency
US6596725B2 (en) *	1997-02-10	2003-07-22	Inspire Pharmaceuticals, Inc.	Use of certain dinucleotides to stimulate removal of fluid in retinal detachment and retinal edema
TW593331B (en) *	1997-07-25	2004-06-21	Inspire Pharmaceuticals Inc	Method for large-scale production of di(uridine 5')-tetraphosphate and salts thereof
NZ501696A (en) *	1997-07-25	2001-08-31	Inspire Pharmaceuticals Inc	Method for large-scale production of sodium and ammonium salts of di(uridine 5')-tetraphosphate
ATE232733T1 (de) *	1998-05-22	2003-03-15	Inspire Pharmaceuticals Inc	Therapeutische dinucleotide und deren derivate
CN1151166C (zh) *	1998-10-02	2004-05-26	雅玛山酱油株式会社	二尿苷四磷酸或其盐的晶体和其制备方法、以及制备该化合物的方法
WO2000039145A1 (en) *	1998-12-23	2000-07-06	The University Of North Carolina At Chapel Hill	Targeted gene transfer using g protein coupled receptors
DE60006814T2 (de) *	1999-06-30	2004-05-19	Yamasa Corp., Choshi	Dinucleotid-kristalle

2000
- 2000-06-30 DE DE60006814T patent/DE60006814T2/de not_active Expired - Lifetime
- 2000-06-30 PL PL352363A patent/PL202200B1/pl unknown
- 2000-06-30 EA EA200200109A patent/EA004707B1/ru not_active IP Right Cessation
- 2000-06-30 WO PCT/JP2000/004336 patent/WO2001002416A1/ja not_active Ceased
- 2000-06-30 EP EP00942412A patent/EP1191032B1/en not_active Expired - Lifetime
- 2000-06-30 EP EP03018399A patent/EP1362862B1/en not_active Expired - Lifetime
- 2000-06-30 BR BR0012205-0A patent/BR0012205A/pt not_active Application Discontinuation
- 2000-06-30 NZ NZ516301A patent/NZ516301A/en not_active IP Right Cessation
- 2000-06-30 PL PL384307A patent/PL202176B1/pl unknown
- 2000-06-30 CA CA002376860A patent/CA2376860C/en not_active Expired - Fee Related
- 2000-06-30 DE DE60021629T patent/DE60021629T2/de not_active Expired - Lifetime
- 2000-06-30 MX MXPA02000035A patent/MXPA02000035A/es active IP Right Grant
- 2000-06-30 CZ CZ20014502A patent/CZ303172B6/cs not_active IP Right Cessation
- 2000-06-30 AT AT03018399T patent/ATE300551T1/de not_active IP Right Cessation
- 2000-06-30 AU AU57067/00A patent/AU767136B2/en not_active Ceased
- 2000-06-30 US US09/700,728 patent/US6617444B1/en not_active Expired - Lifetime
- 2000-06-30 AT AT00942412T patent/ATE255123T1/de not_active IP Right Cessation
- 2000-06-30 ES ES03018399T patent/ES2245431T3/es not_active Expired - Lifetime
- 2000-06-30 JP JP2001507852A patent/JP3421666B2/ja not_active Expired - Fee Related
- 2000-06-30 KR KR1020017016184A patent/KR100593723B1/ko not_active Expired - Fee Related
- 2000-06-30 HU HU0201531A patent/HU229225B1/hu not_active IP Right Cessation
- 2000-06-30 ES ES00942412T patent/ES2211566T3/es not_active Expired - Lifetime
- 2000-06-30 CN CNB008097356A patent/CN1144811C/zh not_active Expired - Fee Related
- 2000-06-30 SK SK1870-2001A patent/SK284178B6/sk not_active IP Right Cessation
- 2000-06-30 IL IL14716300A patent/IL147163A/xx not_active IP Right Cessation
2001
- 2001-12-20 ZA ZA200110468A patent/ZA200110468B/en unknown
- 2001-12-27 NO NO20016381A patent/NO321169B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE255123T1 (de)	2003-12-15
ZA200110468B (en)	2003-04-04
MXPA02000035A (es)	2003-07-21
DE60021629T2 (de)	2006-01-05
JP3421666B2 (ja)	2003-06-30
IL147163A0 (en)	2002-08-14
EP1362862B1 (en)	2005-07-27
EA200200109A1 (ru)	2002-06-27
BR0012205A (pt)	2002-05-28
ES2211566T3 (es)	2004-07-16
CN1144811C (zh)	2004-04-07
EP1191032A1 (en)	2002-03-27
SK18702001A3 (sk)	2002-06-04
EP1191032A4 (en)	2002-07-17
ATE300551T1 (de)	2005-08-15
HUP0201531A2 (en)	2002-08-28
CN1359387A (zh)	2002-07-17
EA004707B1 (ru)	2004-06-24
HUP0201531A3 (en)	2005-02-28
DE60021629D1 (de)	2005-09-01
PL352363A1 (en)	2003-08-25
WO2001002416A1 (en)	2001-01-11
PL202200B1 (pl)	2009-06-30
CA2376860C (en)	2006-11-07
SK284178B6 (sk)	2004-10-05
KR20020028903A (ko)	2002-04-17
NO20016381L (no)	2002-02-28
NZ516301A (en)	2003-07-25
IL147163A (en)	2005-11-20
US6617444B1 (en)	2003-09-09
DE60006814T2 (de)	2004-05-19
KR100593723B1 (ko)	2006-06-30
ES2245431T3 (es)	2006-01-01
CZ303172B6 (cs)	2012-05-09
EP1362862A1 (en)	2003-11-19
PL202176B1 (pl)	2009-06-30
HU229225B1 (en)	2013-09-30
DE60006814D1 (de)	2004-01-08
EP1191032B1 (en)	2003-11-26
CA2376860A1 (en)	2001-01-11
AU5706700A (en)	2001-01-22
NO321169B1 (no)	2006-03-27
AU767136B2 (en)	2003-10-30
CZ20014502A3 (cs)	2002-05-15

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Legal Events

Date	Code	Title	Description
2015-05-11	CHAD	Change of the owner's name or address (par. 44 patent law, par. patentforskriften)	Owner name: MERCK SHARP & DOHME CORP, US
2018-01-22	MM1K	Lapsed by not paying the annual fees